Clinical trials: Complications; Cesarean Section
Postpartum Hemorrhage (Primary)
Effect of Co-administration of Carbetocin and Calcium Chloride on Uterine Tone in Patients Undergoing Elective Cesarean Delivery
Postpartum hemorrhage (PPH) is a leading cause of maternal mortality, and its severity has been increasing globally, including in high-income countries.
- Trial name
- NCT07187544
- Testing
- Calcium Chloride, Carbetocin
- Where
- Canada
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Surgical Site Infection, Surgery--Complications
Prophylaxis of Surgical Wound Infection With Topical Antibiotics
Surgical site infection (SSI) is the main complication of surgery. The prevention of superficial SSI by topical prophylaxis is controversial.
- Conditions
- Surgical Site Infection, Surgery--Complications, Colorectal Surgery, Cesarean Section; Infection
- Trial name
- NCT04476212
- Testing
- Topical antibiotic prophylaxis
- Where
- Spain
- Volunteers
- 560 people
- Sponsor
- Hospital de Granollers
Postoperative Pain
The Effect of Quran of Post Operative Pain
Postoperative pain management is crucial for surgical patients. Management of postoperative pain entails reducing painful symptoms, improving the quality of recovery and resuming normal daily living activities.
- Trial name
- NCT02589834
- Testing
- Quran group
- Where
- Egypt
- Volunteers
- 118 people
- Sponsor
- Assiut University
Tranexamic Acid Administration, Postpartum Hemorrhage
Tranexamic Acid for Reducing Blood Loss in High-Risk Cesarean Delivery
This randomized study evaluated whether prophylactic tranexamic acid (TXA) reduces perioperative blood loss in women at increased risk of postpartum hemorrhage undergoing elective cesarean delivery.
- Conditions
- Tranexamic Acid Administration, Postpartum Hemorrhage, Blood Transfusion, Perioperative Blood Loss
- Trial name
- TXA (NCT07870499)
- Testing
- Tranexamic Acid
- Where
- Turkey (Türkiye)
- Volunteers
- 84 people
- Sponsor
- Mert Yetgin
Postoperative Pain
A Novel Analgesic Method for Postoperative Pain Relief After Cesarean Section: Intraoperative Superior Hypogastric Block
Cesarean section is the most common inpatient surgical procedure in the United States with 1.3 million cesarean deliveries performed in 2015.
- Trial name
- NCT03897764
- Testing
- Intraoperative superior hypogastric plexus block
- Where
- Turkey (Türkiye)
- Volunteers
- 154 people, healthy volunteers welcome
- Sponsor
- Maltepe University
Postpartum Hemorrhage
Efficacy of Oxytocin vs. Carbetocin in Prevention of Postpartum Hemorrhage After Cesarean Section
Postpartum hemorrhage (PPH) is a common complication of childbirth and a leading cause of maternal morbidity and mortality. The prompt and effective treatment of subjects with PPH would reduce operation risks.
- Trial name
- NCT02079558
- Testing
- Carbetocin, Oxytocin
- Where
- Iran
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Shahid Beheshti University of Medical Sciences
Uterine Bleeding, Atony, Uterine
Questionnaire for Obstetricians and Anesthesiologist
The research was planned as a face-to-face survey evaluation. The questionnaire will be applied to obstetricians and anesthesiologists working in public and private hospitals.
- Conditions
- Uterine Bleeding, Atony, Uterine, Cesarean Section Complications
- Trial name
- NCT05089721
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people
- Sponsor
- Gazi University
Cesarean Section Complications, Scar; Deformity
Uterine Closure Techniques and Cesarean Scar Defect Risk
Cesarean operations are one of the most common obsetric operations and have an increasing trend in all over the world. However unfortunately the operation techniques have not been standardized yet.
- Trial name
- NCT05100147
- Testing
- Uterine closure during Cesarean section
- Where
- Turkey (Türkiye)
- Volunteers
- 43 people
- Sponsor
- Mersin University
Morbidly Adherent Placenta
Comparison Between Bladder Dissection Before and After Uterine Incision in Cesarean Section for Morbidly Adherent Placenta
Comparison between bladder dissection at the beginning of cesarean section For morbidly adherent placenta and between delaying dissection until planning for cesarean hysterectomy
- Trial name
- NCT03676855
- Testing
- bladder dissection
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Cesarean Section, Surgical Site Infection
Effect of Betadine Vaginal Cleansing Before Cesarean Section to Reduce Postoperative Infectious Morbidity
This randomized controlled trial aims to evaluate the efficacy of preoperative vaginal cleansing with 5% povidone-iodine in reducing postoperative infectious morbidity among women undergoing cesarean section.
- Conditions
- Cesarean Section, Surgical Site Infection, Endometritis
- Trial name
- NCT07715409
- Testing
- Povidone-iodine 5% solution
- Where
- Egypt
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Mohamed Mousa Mohamed Mousa
Cesarean Section Complications, Hemodynamic Instability
Impact of Carbetocin Administration on Heart Rate When Given as an Infusion Versus as a Bolus.
Prospective, randomized and controlled study who will be conducted at Maisonneuve-Rosemont hospital with the following objectives: To determine if an infusion of carbetocin over 10 minutes will reduce hemodynamic side effects…
- Trial name
- NCT03404544
- Testing
- Carbetocin bolus, Carbetocin infusion
- Where
- Canada
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Ciusss de L'Est de l'Île de Montréal
Opioid-use Disorder, Pain, Postoperative
BRIDGE Percutaneous Nerve Stimulation for Cesarean Delivery Pain Control
This is a randomized, placebo controlled and natural-history controlled trial to investigate the effectiveness of NSS-2 BRIDGE® for postpartum women with AND without opioid use disorder (OUD).
- Trial name
- NCT04365465
- Testing
- NSS-2 Bridge, Inactive NSS-2 Bridge, Active control
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Grace Lim, MD, MS
Postoperative Pain, Recovery After Cesarean Delivery
Kinesio Taping for Pain and Recovery After Cesarean Delivery
This study examined whether elastic therapeutic tape, known as kinesio tape, applied to the lower abdomen after cesarean delivery could reduce pain and improve recovery when added to standard postoperative care.
- Trial name
- NCT07855809
- Testing
- Kinesio Taping
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people
- Sponsor
- Ibrahim Ethem Kirez
Isthmocele, Cesarean Scar Defect
Clinical Impact of Uterine Repair During Cesarean Section with Barbed Suture on the Incidence of Isthmocele
Pregnant women, irrespective of their pregnancy risk, who undergo a cesarean section for any reason will be randomized to one of two suturing techniques: conventional suture or barbed suture for uterine repair after the cesarean…
- Conditions
- Isthmocele, Cesarean Scar Defect, Pelvic Pain, Spotting
- Trial name
- CESARIS (NCT06691750)
- Testing
- Barbed suture, Conventional smooth suture
- Where
- Spain
- Volunteers
- 364 people, healthy volunteers welcome
- Sponsor
- Hospital Clinic of Barcelona
Cesarean Section, Pain, Postoperative
RCT (Randomized Controlled Trial) of IV Acetaminophen for Post Cesarean Pain Relief
This study is being done to evaluate the scheduled use of intravenous (IV) acetaminophen among cesarean section patients. The study hopes to find out if patients who receive scheduled IV acetaminophen for 48 hours following…
- Trial name
- NCT02046382
- Testing
- IV Acetaminophen
- Where
- United States
- Volunteers
- 132 people
- Sponsor
- TriHealth Inc.
Postpartum Hemorrhage
Effect of Ephedrine, Phenylepinephrine, and Norepinephrine on Myometrial Contractility in Pregnant People With Type II and Gestational Diabetes During Cesarean Section: An In-vitro Study
The goal of this study is to learn about how medication that is used to help treat low blood pressure during a Cesarean delivery (CD) can cause changes to the uterine muscle tissue and its ability to contract, in patients with…
- Trial name
- NCT06285396
- Testing
- Ephedrine, Phenylephrine, Norepinephrine
- Where
- Canada
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Pre-Eclampsia, Cesarean Section
Combined Colloids And Crystalloids Versus Crystalloids in Women With Preeclampsia Undergoing Cesarean Delivery
This study will compare between combination of colloids/crystalloids and crystalloids in women with preeclampsia undergoing elective cesarean delivery under spinal anesthesia
- Trial name
- NCT03252496
- Testing
- Spinal Anesthesia, Intrathecal Bupivacaine, Intrathecal Fentanyl
- Where
- Egypt
- Volunteers
- 140 people
- Sponsor
- Mansoura University
Preecalmpsia
Incidence of Postoperative Diaphragmatic Dysfunction in Pregnant Women With Preeclampsia
Preeclampsia with severe features remains a leading contributor to maternal morbidity and mortality, particularly in low- and middle-income countries.
- Trial name
- NCT07443345
- Where
- Egypt
- Volunteers
- 52 people
- Sponsor
- Cairo University
Pregnancy Related, Cesarean Section
Fascial Closure and Post-caesarean Pain
This study will evaluate post-operative pain in patients undergoing elective caesarean sections based on the method of fascial closure.
- Conditions
- Pregnancy Related, Cesarean Section, Post-operative Pain, Fascial Closure
- Trial name
- NCT04999670
- Testing
- Fascial closure method during caesarean section via pfannenstiel incision.
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Sunnybrook Health Sciences Centre
Cesarean Section Complications, Cesarean Section Pain
Insufficient Regional Anesthesia and Conversion to General Anesthesia for Cesarean Section A Qualitative Multicenter Study
Background In Denmark, approximately 20% of all children are born via cesarean section (C-section), making it the most common surgical procedure (also internationally).
- Conditions
- Cesarean Section Complications, Cesarean Section Pain, Regional Anesthesia
- Trial name
- NCT06669156
- Where
- 7 sites in Denmark
- Volunteers
- 21 people
- Sponsor
- Sygehus Lillebaelt
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