Clinical trials: Complications; Cesarean Section
Complications; Cesarean Section
Comparison of Uterine Repair Methods for Cesarean Delivery
This study is designed to compare the exteriorization of the uterus versus the in situ repair for closure of the hysterotomy incision with a completely standardized anesthetic protocol.
- Trial name
- NCT02587013
- Testing
- Type A of uterine repair: In situ, Type B of uterine repair: Exteriorization
- Where
- Canada
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Maisonneuve-Rosemont Hospital
Postpartum Hemorrhage, Twin
Oxytocin at Elective Cesarean Deliveries: A Dose-finding Study in Women With Twin Pregnancy
Postpartum hemorrhage (PPH) due to uterine atony is a major cause of maternal morbidity and mortality. Uterotonic drugs are used to improve the muscle tone of the uterus after birth and these are effective at reducing the…
- Trial name
- NCT04025658
- Testing
- Oxytocin
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Pregnancy Complications
Risk of Cesarean Section in Primiparous Women Over 35 Years of Age.
The investigators reviewed Saint Thomas Maternity Hospital's database during a 5 year period and compared two cohorts of patients (primiparous women over 35 years of age and primiparous woman between 20 and 34 years of age).
- Trial name
- NCT03771976
- Testing
- Cesarean section, No cesarean section
- Where
- Panama
- Volunteers
- 572 people
- Sponsor
- Saint Thomas Hospital, Panama
Obstetric Labor Complications, Hemorrhage
Coagulation Factor Changes Associated With Postpartum Hysterectomies
The purpose of this study is to examine components of the coagulation system in women undergoing postpartum hysterectomy and to compare laboratory parameters of coagulation in these women to women at increased risk for a…
- Conditions
- Obstetric Labor Complications, Hemorrhage, Complications; Cesarean Section
- Trial name
- NCT00456547
- Testing
- Blood Draw
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Placenta Previa
Tranexamic Acid vs Vasopressin in Placenta Previa Trial
Placenta previa is a major obstetric condition associated with increased risk of excessive blood loss during cesarean section, leading to maternal morbidity and mortality.
- Trial name
- TXA-VASO-PP (NCT07423156)
- Testing
- Group A: Tranexamic acid, Group B: Vasopressin
- Where
- Pakistan
- Volunteers
- 58 people
- Sponsor
- Allama Iqbal Medical College
Cesarean Section Complications, Cesarean Section Niche
Effect of Decidual Sparing in cs Niche Formation
Assessing the impact of endometrial sparing at double-layer uterine closure as a specific surgical technique in CS to reduce the rate of post-cessarian delivery niche develoment
- Trial name
- NCT06324331
- Testing
- Decidual sparing, Non decidual sparing
- Volunteers
- 184 people, healthy volunteers welcome
- Sponsor
- Assiut University
Postpartum Hemorrhage
Comparison of IV Ergonovine With IM Carboprost, With Oxytocin IV, During Cesarean Section for Failure to Progress
Patients having Cesarean section after they have been in labor for many hours bleed much more, in average twice as much, as compared with patients having an elective Cesarean section.
- Trial name
- NCT01869556
- Testing
- Oxytocin, Ergot, Carboprost
- Where
- Canada
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Ceserean Section and Postoperative Pain
Transversus Abdominis and Transversalis Fascia Plane Block Combination for Cesarean Section
Cesarean delivery rates are rising globally, and effective postoperative analgesia is crucial for maternal recovery and newborn care.
- Trial name
- TAPTFPB (NCT06944912)
- Testing
- Transversalis fascia plane block and transversus abdominis plane block, Intrathecal Morphine
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Ataturk University
Postpartum Hemorrhage
The Efficacy of Tranexamic Acid in Preventing Postpartum Haemorrhage After Caesarean Section
This study seeks to determine if the using tranexamic acid prophylactically at caesarean section will prevent postpartum haemorrhage which is a major cause of maternal mortality in Zimbabwe and globally.
- Trial name
- ETAPPH (NCT04733157)
- Testing
- Tranexamic acid injection
- Where
- 2 sites in Zimbabwe
- Volunteers
- 1,226 people
- Sponsor
- University of Zimbabwe
Surgical Site Infection Following Cesarean Delivery, Cesarean Section Complications
Evaluation of an mHealth-CHW Tool for Post-c-section Follow-up in Rural Rwanda
Cesarean sections (c-sections) are one of the most common surgical procedures done globally. However, there has been an increase in the number of c-section related complications.
- Trial name
- NCT07369700
- Testing
- mHealth Community Health Worker Intervention for post-cesarean follow up
- Where
- Rwanda
- Volunteers
- 1,350 people
- Sponsor
- University of North Carolina, Chapel Hill
Postoperative Pain
Levobupivacaine to the Surgical Wound Following Cesarean
The postoperative period following cesarean is associated with moderate to severe pain that requires a considerable amount of analgesics that carry with them side-effects such as nausea, vomiting, fatigue and immobilization.
- Trial name
- NCT01458431
- Testing
- Levobupivacaine, NaCl
- Where
- Spain
- Volunteers
- 70 people
- Sponsor
- Manuel Ángel Gómez-Ríos
Hemorrhage of Cesarean Section and/or Perineal Wound, Postpartum Hemorrhage
Role of Tranexamic Acid Versus Uterine Cooling at Caesarean Section
This study aims to compare role of a prophylactic predefined intravenous Tranexamic Acid dose versus intraoperative Uterine Cooling in reducing blood loss and incidence of postpartum hemorrhage at secondary CS.
- Conditions
- Hemorrhage of Cesarean Section and/or Perineal Wound, Postpartum Hemorrhage, Uterine Atony
- Trial name
- NCT02780245
- Testing
- Tranexamic Acid, Intraoperative Uterine Cooling
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Talkha Central Hospital
Pregnancy Complications, Cesarean Section Complications
A Quality Improvement Project - Peripartum Operating Room Leveling System
Investigators propose a four-category triaging system to delineate and facilitate the communication and action plan for all types of obstetric OR cases via a multidisciplinary approach.
- Conditions
- Pregnancy Complications, Cesarean Section Complications, Morbidity;Perinatal
- Trial name
- NCT03552419
- Volunteers
- 1,380 people
- Sponsor
- Johns Hopkins University
Complications; Cesarean Section
Preoperative Cesarean Section Intravenous Acetaminophen and Postoperative Pain Control
To evaluate the use of maternal opiates for pain control post cesarean delivery in those patients that received intravenous acetaminophen 1000 mg in 150 mL of normal saline, infused 30 minutes prior to incision compared to…
- Trial name
- NCT02694653
- Testing
- Acetaminophen
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Tennessee Graduate School of Medicine
Pain, Postoperative
Effect of Adding Hyaluronidase to Bupivacaine in Transversus Abdominis Plane Block for Cesarean Section
Since TAP block needs to affect several nerves in single tissue plane with a single prick, hyaluronidase is expected to aid greatly in the spread of the LA and help the block.
- Trial name
- NCT05671172
- Testing
- Hyaluronidase, Bupivacaine Injection
- Where
- Egypt
- Volunteers
- 114 people
- Sponsor
- Benha University
Postpartum Hemorrhage (Primary)
OBS-QoR-10 in Patients With and Without Postpartum Hemorrhage
Postpartum hemorrhage (PPH) remains a leading cause of maternal death and morbidity. Moreover, it also contributes to psychological trauma such as depression and post-traumatic stress disorder.
- Trial name
- NCT07199803
- Testing
- Obstetric Quality of Recovery-10 (ObsQoR-10©) Scoring Tool
- Where
- Canada
- Volunteers
- 136 people, healthy volunteers welcome
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Wound Heal, Cesarean Section Complications
The Effect of Suturing Material on Scar Healing
We want to compare the effects of 2 suture materials (monofilament and multifilament) on healing of the uterine scar after a cesarean delivery.
- Conditions
- Wound Heal, Cesarean Section Complications, Cesarean Wound Disruption, Suture Related Complication
- Trial name
- NCT03968783
- Testing
- Monofilament suture, Multifilament suture
- Where
- Turkey (Türkiye)
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Cesarean Section Complications, Attachment Disorder
Attachment Predicts Post Cesarean Pain
The Adult Attachment Style (AAS) is a questionnaire designed to measure how an adult generally feels in their close personal relationships.
- Conditions
- Cesarean Section Complications, Attachment Disorder, Post Operative Recovery
- Trial name
- NCT04863651
- Where
- Canada
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Western University, Canada
Cesarean Section, Post Operative Pain
Ilioinguinal Iliohypogastric Nerve Block as Adjunct to Spinal Anesthesia for Cesarean Section
The aim of the present controlled randomized study is to compare between ilioinguinal/iliohypogastric nerve block (IINB) and morphine as adjuncts to spinal anesthesia for cesarean section regarding quality of post-operative…
- Trial name
- NCT06108895
- Testing
- ilio-inguinal/ilio-hypogastric nerve block (IINB), intrathecal morphine
- Where
- Egypt
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Tanta University
Cesarean Section Complications, Pain, Postoperative
Analgesic Efficacy of Surgeon-administered Transversus Abdominis Plane Blocks for Caesarean Section.
The purpose of this research study is to evaluate whether or not adding a Transversus Abdominis Plane Block (TAP block) improves pain control for patients having a cesarean section.
- Trial name
- NCT06324942
- Testing
- Surgeon-administered Transversus Abdominis Plane Block 0.25% bupivicaine 0.25 mL/kg
- Where
- Canada
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Calgary
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