Clinical trials: Complications Surgical
Overall Survival, Postoperative Complications
Standardization of Laparoscopic Surgery for Right Hemi Colon Cancer (SLRC)
To standardize the surgery for advanced right hemi colon cancer with laparoscopy and investigate whether extended lymphadenectomy (CME) could improve disease-free survival in patients with right colon cancer, compared with D3…
- Conditions
- Overall Survival, Postoperative Complications, Metastasis, Stage, Colon Cancer
- Trial name
- NCT02942238
- Testing
- CME, D3
- Volunteers
- 582 people
- Sponsor
- Ruijin Hospital
Hyponatremia, Syndrome of Inappropriate ADH (SIADH) Secretion
Tolvaptan Versus Fluid Restriction in SIADH
Context. The relevance of hyponatremia has been acknowledged by guidelines from the United States of America (2013) and Europe (2014). However, treatment recommendations differ due to limited evidence. Objective.
- Conditions
- Hyponatremia, Syndrome of Inappropriate ADH (SIADH) Secretion, Pituitary
- Trial name
- NCT04119206
- Volunteers
- 334 people
- Sponsor
- University of Erlangen-Nürnberg Medical School
Stress Urinary Incontinence (SUI), Female Stress Urinary Incontinence
Sling Insertion Angle and Outcomes in Single-Incision Midurethral Sling Surgery
This study aims to evaluate the effect of sling insertion angle on surgical outcomes and quality of life in women with stress urinary incontinence (SUI) undergoing single-incision midurethral sling surgery.
- Trial name
- SUI-SLING (NCT07530484)
- Where
- Taiwan
- Volunteers
- 184 people
- Sponsor
- Shin Kong Wu Ho-Su Memorial Hospital
Postoperative Pain
Effect of Psychosocial and Psychophysical Factors and Preemptive Analgesia on Postoperative Pain in Upper Limb Surgery
The purpose of this study is to define the role of preemptive systemic analgesia in combination with regional anesthetic techniques on postoperative pain following upper limb surgery in different subgroups of patients with…
- Trial name
- NCT05248152
- Testing
- Paracetamol and Ibuprofen, Pregabalin 150mg
- Where
- Slovenia
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University Medical Centre Ljubljana
Spondylolisthesis, Lumbar Disc Herniation
Erector Spinae Plane Block as Pain Management After Lumbar Fusion Surgery
Rationale: Lumbar spine surgery is associated with high postoperative pain scores and analgesic use, despite use of multimodal analgesia.
- Conditions
- Spondylolisthesis, Lumbar Disc Herniation, Lumbar Spinal Stenosis, Lumbar Disc Disease
- Trial name
- RCT-ESPB (NCT05345249)
- Testing
- Ropivacaine Hydrochloride Injection, Sodium chloride
- Where
- Netherlands
- Volunteers
- 76 people
- Sponsor
- Ilse van de Wijgert
Urinary Incontinence, Urinary Stress Incontinence
Pregnancy After Tension-free Vaginal Tape and Other Mid-urethral Sling Procedures
The purpose of this study is to determine the interactions between pregnancy and urinary stress incontinence in women with a mid-urethral sling (MUS).
- Conditions
- Urinary Incontinence, Urinary Stress Incontinence, Pregnancy Complications
- Trial name
- PregnanT (NCT02999347)
- Where
- Norway
- Volunteers
- 80 people
- Sponsor
- Oslo University Hospital
Postoperative Complications
The Effect of Telephone Nursing Education and Counseling Services Given to Satisfaction Level and Self-Care Strength
In the post-discharge period, it is important to follow the patients from home by telephone and to provide the necessary nursing education and counseling services, increasing the self-care powers of the patients, increasing their…
- Trial name
- NCT05487638
- Testing
- Nursing Education and Counseling Service Provided to Patients by Video Calling on the Phone
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ataturk University
Clear Cell Renal Cell Carcinoma
Neoadjuvant PD-L1 Inhibitor Plus Anlotinib for Kidney Preservation in Complex Renal Cell Carcinoma
This is a prospective, multicenter, single-arm phase II study evaluating the efficacy and safety of neoadjuvant PD-L1 inhibitor TQB2450 in combination with anlotinib in patients with locally advanced, high-complexity (RENAL score…
- Trial name
- NCT07602101
- Testing
- TQB2450 + Anlotinib
- Volunteers
- 33 people
- Sponsor
- RenJi Hospital
Thrombosis, Deep Vein Thrombosis
Thromboprophylaxis in Patients Undergoing Orthopedic Surgeries; Using Propensity Score Matching
Venous thromboembolism (VTE), including deep vein thrombosis (DVT) and pulmonary embolism (PE), is a common post-operative complication.
- Conditions
- Thrombosis, Deep Vein Thrombosis, Surgery--Complications
- Trial name
- NCT03483181
- Testing
- Xarelto (rivaroxaban), Lovenox (enoxaparin)
- Where
- Vietnam
- Sponsor
- Hanoi Medical University
Laparoscope, Malignant Ovarian Tumor
Clinical Effect Evaluation of Laparoscopic Surgery for Ovarian Benign Tumors by Different Approaches
Main purpose: To compare the intraoperative and postoperative recovery of laparoscopic surgery for ovarian benign tumors through different approaches; Secondary objective: Will vNOTES increase the risk of cesarean section during…
- Conditions
- Laparoscope, Malignant Ovarian Tumor, Single-site Surgery
- Trial name
- NCT06047730
- Testing
- operation ways
- Where
- China
- Volunteers
- 173 people
- Sponsor
- Yingchun Ma
Postoperative Wound Infection, Postoperative Outcome
Effect of Perioperative Hemodynamic Optimization on the Immune Function Parameters of Peripheral Blood Monocytes After Cardiac Surgery
Cardiac surgery patients have a high risk to suffer from postoperative infections. Some studies have shown, that humoral and cellular factors are associated with perioperative immunodysfunction and can increase the risk of…
- Trial name
- Algebra (NCT01184430)
- Testing
- Pulse contour cardiac output device
- Where
- Germany
- Volunteers
- 40 people
- Sponsor
- Charite University, Berlin, Germany
Clavicle Fracture
The Scandinavian Displaced Lateral Clavicle Trial
A multicentre multinational RCT to investigate whether non-surgical treatment is non-inferior to surgical treatment for displaced extraarticular lateral clavicle fractures in adults.
- Trial name
- ScanDiLaC (NCT06981065)
- Testing
- Simple Sling and Physiotherapy, Surgical treatment
- Where
- 11 sites in Denmark, Finland and 2 more
- Volunteers
- 96 people
- Sponsor
- Uppsala University
Postoperative Vomiting
Effect of Intravenous Fluid Therapy on Postoperative Vomiting in Children Undergoing Otorhinolaryngological Surgery
The purpose of this randomized clinical trial is to evaluate the interaction of intravenous fluid therapy during otorhinolaryngological surgery, on postoperative vomiting.
- Trial name
- NCT01575600
- Testing
- Intraoperative lactated Ringer's solution
- Where
- Chile
- Volunteers
- 100 people
- Sponsor
- Ignacio Cortínez F.
Haemorrhoidal Disease, Post-operative Pain
Mesoglycan for Pain Control After Open Excisional HAEMOrrhoidectomy
Haemorrhoidal disease (HD) is the most common proctological disease, with a prevalence that can reach up to 39% of the population.
- Conditions
- Haemorrhoidal Disease, Post-operative Pain, Thrombosis
- Trial name
- MeHAEMO (NCT04481698)
- Testing
- Mesoglycan
- Where
- Italy
- Volunteers
- 398 people
- Sponsor
- Societa Italiana di Chirurgia ColoRettale
Benzodiazepines, Bladder Cancer
Impact of Remimazolam on Prognosis After Bladder Cancer Surgery
Bladder cancer is one of the most common genitourinary cancers. Transurethral resection of bladder tumor (TURBT) is the standard therapy for nonmuscle invasive bladder cancer.
- Conditions
- Benzodiazepines, Bladder Cancer, Delirium, Surgery
- Trial name
- NCT04532606
- Testing
- Remimazolam, Propofol
- Where
- 6 sites in China
- Volunteers
- 1,128 people
- Sponsor
- Peking University First Hospital
Perioperative Red Blood Cell Transfusion
Blood Transfusion Strategies During Major Surgery
The goal of this randomized clinical trial is to address the uncertainty surrounding blood transfusion strategies in the operating room for adult patients undergoing major surgery.
- Trial name
- TOPGUN (NCT07748663)
- Testing
- Restrictive Transfusion, Liberal transfusion
- Where
- 2 sites in Canada
- Volunteers
- 5,058 people
- Sponsor
- Ottawa Hospital Research Institute
Postoperative Pain, Shoulder Surgery
Cervical Erector Spinae Block for Shoulder Surgery
Arthroscopic shoulder surgery is often associated with moderate to severe postoperative pain that may interfere with patients' early mobilization, recovery and quality of life.
- Trial name
- NCT04397549
- Testing
- Cervical erector spinae plane block, Intravenous morphine patient controlled analgesia device
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Konya Necmettin Erbakan Üniversitesi
Postoperative Pain
Comparison of Paravertebral Versus Epidural Block for Post-thoracotomy Pain Control
This is a randomized, assessor-blinded, non-inferiority clinical trial comparing continuous thoracic paravertebral block (BPV) versus continuous thoracic epidural block (BPD) for postoperative pain control in adult patients…
- Trial name
- NCT07763249
- Testing
- Continuous Thoracic Paravertebral Block, Continuous Thoracic Epidural Block
- Where
- Brazil
- Volunteers
- 80 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Postoperative Cognitive Dysfunction
POCD: Correlations With the Gene Polymorphism and the Concentrations of Plasma Homocysteine, Folic Acid and Vitamin B12.
To study on the Postoperative Cognitive Dysfunction: Correlations With the Gene Polymorphism and the Concentrations of Plasma Homocysteine, Folic Acid and Vitamin B12.
- Trial name
- NCT03084393
- Where
- China
- Volunteers
- 215 people, healthy volunteers welcome
- Sponsor
- Xuzhou Medical University
Postoperative Pain, Acute
Erector Spinae Plane Block Versus Quadratus Lumborum Block for Open Renal Surgeries in Children
Open renal surgeries are associated with significant postoperative pain; early control of the perioperative pain is associated with decrease of hemodynamic variations during the surgery, early mobilization, better quality of…
- Trial name
- NCT05386121
- Testing
- Ultrasound-guided Erector Spinae Plane Block, Ultrasound-guided Quadratus Lumborum Block, Ultrasound Machine
- Volunteers
- 60 people
- Sponsor
- Cairo University