Clinical trials: Comprehension
Sleep
Memory Consolidation in Pharmacologically Enhanced Naps
This study will examine whether various drugs affecting sleep cycles can improve different kinds of memory.
- Trial name
- NCT00777829
- Testing
- zolpidem
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Anxiety, Anxiety Disorders
Anxiety, Inflammation, Stress, and Cannabinoids
This study investigates whether the anxiolytic effects and anti-inflammatory properties of cannabis vary as a function of the ratio of CBD to THC, with the goal that these effects may shed light on the mixed data linking cannabis…
- Conditions
- Anxiety, Anxiety Disorders, Anxiety Generalized, Anxiety Chronic
- Trial name
- NCT03491384
- Testing
- Cannabis (smoked flower, ingested edible)
- Where
- United States
- Volunteers
- 361 people
- Sponsor
- University of Colorado, Boulder
Decision Aid
Using Visual Arrays to Support Understanding of Genetic Risk
The goal of this study is to understand how people understand risk from genetic testing. The investigators want to understand what visual aid best helps people accurately assess risk.
- Trial name
- NCT06994832
- Testing
- Visual Array, Narrative Visual Array, Choice
- Where
- United States
- Volunteers
- 1,045 people, healthy volunteers welcome
- Sponsor
- Stephanie B. Seminara, MD
Hepatitis B Virus
A Study to Provide a Better Understanding of Baraclude's Pharmacokinetic Properties in a Real World Clinical Setting
A Pharmacokinetics study of Baraclude in a real world clinical setting in Japan.
- Trial name
- NCT03083821
- Testing
- Baraclude
- Where
- Japan
- Volunteers
- 6 people
- Sponsor
- Bristol-Myers Squibb
Malnutrition
The Dietetic Consultation: an Illuminative Evaluation
This study aims to understand the experience of the dietetic consultation from the perspective of nutritionally vulnerable older patients receiving oral nutrition support and dietitians, as well as other key stakeholders involved…
- Trial name
- NCT03509116
- Testing
- Observations, documents, Interviews, key stakeholders, documents
- Where
- United Kingdom
- Volunteers
- 45 people
- Sponsor
- King's College London
Cannabis Use Disorder
Understanding Effects of Cannabis Use and Abstinence on Neural Glutamate Homeostasis
This study will be the first in vivo human multimodal neuroimaging study exploring the relationship between mGluR5 availability (PET), neural oscillations (EEG), and cognitive function in people with CUD.
- Trial name
- NCT05664763
- Testing
- [18F]FPEB with PET, Cannabis abstinence
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Yale University
Sleep Apnea Syndromes, Sleep Initiation and Maintenance Disorders
Understanding the Sleep Apnea/Insomnia Interaction
Nearly half of all patients with obstructive sleep apnea have insomnia symptoms, and in some, but not all cases, these insomnia symptoms are caused by the obstructive sleep apnea.
- Trial name
- NCT01824472
- Testing
- CPAP, CBT, CC
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- University of Pennsylvania
Hypertension
Understanding the Exercise-Hypertension Paradox
Hypertension affects 37% of the Veteran population, making it the most common medical condition treated by the VA Health Care System. Physical activity is the first line of defense in the treatment and management of hypertension.
- Trial name
- NCT02034422
- Testing
- Oral Antioxidant, Exercise rehabilitation
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Rheumatoid Arthritis
Enhancing Patient Ability to Understand and Utilize Complex Information Concerning Medication Self-management
The aim of the proposed project is to compare the effectiveness of two strategies designed to enhance patient understanding of medication risks/benefits: (1) Medication Guides, mandated for many medications by the Food and Drug…
- Trial name
- NCT02820038
- Testing
- Medication Guides, SMART Program, Drug Facts Boxes
- Where
- United States
- Volunteers
- 286 people
- Sponsor
- University of North Carolina, Chapel Hill
Stroke, Hemiparesis
Perinatal Stroke: Understanding Brain Reorganization
The incidence of perinatal stroke is relatively common, as high as 1 in 2,300 births, but little is known about the resulting changes in the brain that eventually manifest as cerebral palsy (CP).
- Trial name
- NCT02743728
- Testing
- Magnetic Resonance Imaging, Transcranial Magnetic Stimulation, General Movement Assessment
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Minnesota
Preterm Birth, Child Development
Preemie Tots: A Pilot Study to Understand the Effects of Prematurity in Toddlerhood
The purpose of this study is to examine whether supplementation with certain polyunsaturated fatty acids can help development and behavior of children born preterm.
- Conditions
- Preterm Birth, Child Development, Child Behavior
- Trial name
- NCT01683565
- Testing
- LCPUFA oil supplement
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- Sarah Keim
Schizophrenia, Negative Type; Schizophrenic
Using Transcranial Magnetic Stimulation (TMS) to Understand 'Negative' Symptoms of Schizophrenia
The main purpose of this study is to learn how transcranial magnetic stimulation (TMS) helps improve negative symptoms of schizophrenia.
- Conditions
- Schizophrenia, Negative Type; Schizophrenic, Schizo Affective Disorder
- Trial name
- NCT03648268
- Testing
- repetitive Transcranial Magnetic Stimulation (rTMS)
- Where
- United States
- Volunteers
- 47 people
- Sponsor
- Beth Israel Deaconess Medical Center
Gender Dysphoria
Understanding Perceived Access and Receipt of Gender-affirming Treatments Among Transgender Veterans
Transgender Veterans (trans Vets) frequently experience gender dysphoria or distress related to discord between their gender identity and birth sex.
- Trial name
- NCT06615401
- Where
- United States
- Volunteers
- 986 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Mental Health Issue, Hiv
Healthy Mothers: an Intervention to Support Perinatal Women Living With HIV in Kenya
The investigators will recruit 40 pregnant women living with HIV divided into 2 groups (n=20 intervention group, n=20 control group).
- Conditions
- Mental Health Issue, Hiv, Breastfeeding, Exclusive
- Trial name
- NCT05219552
- Testing
- personalized lactation support
- Where
- 2 sites in Kenya
- Volunteers
- 40 people
- Sponsor
- University of California, San Francisco
Healthy
A Study to Understand the Effect of a Study Medicine Called ARV-471 on Rosuvastatin in Healthy Adults
The purpose of this study is to understand if ARV-471 affects how a BCRP substrate (rosuvastatin) gets into the body in healthy adults.
- Trial name
- NCT05652660
- Testing
- ARV-471, Rosuvastatin
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Pfizer
Spine Fusion
Understanding Non-Response in Spine Fusion Surgery
To identify patient characteristics associated with non-response after spine fusion surgery for the treatment of degenerative disc disease (DDD).
- Trial name
- NCT02611479
- Where
- 4 sites in United States
- Volunteers
- 184 people
- Sponsor
- University of Washington
Physical Disability
Understanding Disparities in Healthcare and Primary Care Provider Quality
The project proposes to fill gaps in the understanding of disparities in healthcare and primary care provider (PCP) quality from the perspectives of adult Medicare beneficiaries with disabilities compared to those without…
- Trial name
- NCT02626910
- Where
- United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
COVID-19
A Study to Understand is the COVID-19 Vaccine BNT162b2 is Safe in Indonesia People
The purpose of this study is to characterize descriptively the BNT162b2 vaccination safety experience among the Indonesian people.
- Trial name
- NCT05621239
- Testing
- BNT162b2
- Where
- Indonesia
- Volunteers
- 260 people
- Sponsor
- Pfizer
Hidradenitis Suppurativa
Evaluating the Effect of a Written Action Plan on Comfort and Understanding of Hidradenitis Suppurativa
This study is being conducted to evaluate if a written action plan for hidradenitis suppurativa (HS) will help patients with hidradenitis suppurativa gain a better understanding of the condition and how to manage the condition on…
- Trial name
- NCT04600375
- Testing
- Verbal consultation, Written Action Plan
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- University of Arkansas
Hepatic Impairment, Healthy Volunteers
A Study to Understand How the Study Medicine (PF-07081532) is Processed in People With Liver Dysfunction
The purpose of this study is to understand the effects of liver functional impairment on the study medicine (PF-07081532). People with liver functional impairment may process the study medicine differently from healthy people.
- Trial name
- NCT05478603
- Testing
- PF-07081532
- Where
- 2 sites in United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Pfizer