Clinical trials: Comprehension, open to volunteers
Atopic Dermatitis
Investigating Participation Patterns of Patients in Atopic Dermatitis Clinical Trials
Clinical trials, specifically focused on atopic dermatitis, are crucial in assessing the safety and efficacy of new treatments. These trials serve as fundamental instruments in determining whether emerging medications outperform…
- Trial name
- NCT06174493
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- Power Life Sciences Inc.
Cancer
Visual Communication: Digital Tool to Improve the Understanding of Treatment Options for Patients With Cancer and Increase Satisfaction of the Overall Experience for Patients, Caregivers, and Providers
This is a study in patients with newly diagnosed cancer to prospectively evaluate the feasibility of integration of a visual communication tool for patients/caregivers/providers by determining whether such a tool can increase…
- Trial name
- NCT06927050
- Testing
- Visual Communication Tool
- Where
- United States
- Volunteers
- 86 people
- Sponsor
- NYU Langone Health
Chronic Kidney Disease (CKD), Health Communication
Patient-centered Precision Medicine Lab Result Communication for Older Adults
For adults ≥65 years and their providers, the investigators will test the usability and design of a tool to replace standard uniform reporting of lab results to patients and their providers with a new personalized Electronic…
- Conditions
- Chronic Kidney Disease (CKD), Health Communication, Patient Comprehension
- Trial name
- NCT07391904
- Testing
- Chronic Kidney Disease (CKD) Lab Result Communication Tool
- Where
- United States
- Volunteers
- 255 people
- Sponsor
- University of California, Los Angeles
Depression, Anxiety Disorders
Understanding the Person, Exploring Change Across Psychotherapies
Identifying predictors and understanding mechanisms of change will inform referral to psychotherapy, triage and right-siting by helping clinicians to understand how their patients are likely to benefit from clinical…
- Trial name
- Xchange (NCT04106713)
- Testing
- Individual Psychotherapy, Internet-delivered Cognitive Behavioural Therapy (iCBT), Group Cognitive Behavioural Therapy (group CBT)
- Where
- Singapore
- Volunteers
- 250 people
- Sponsor
- Institute of Mental Health, Singapore
Healthy Adult
Ivabradine for Heart Rate Reduction During Exercise in Healthy Adults
During exercise, working muscles require more oxygen. The heart meets this demand in two ways: by beating faster (heart rate) and by pumping more blood with each beat (stroke volume).
- Trial name
- NCT07717710
- Testing
- Ivabradine (single oral dose)
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
PTSD
Facilitating Transition to Recommended PTSD Treatment
Cognitive processing therapy (CPT) and prolonged exposure therapy (PE) were widely disseminated as recommended posttraumatic stress disorder (PTSD) treatments.
- Trial name
- NCT05165940
- Testing
- Treatment As Usual, New Health Services Intervention
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- VA Office of Research and Development
Hepatic Encephalopathy
Revealing Engagement Patterns Among Hepatic Encephalopathy Patients
This study aims to investigate the influences behind patient choices regarding involvement, discontinuation, or re-engagement in hepatic encephalopathy clinical trials.
- Trial name
- NCT06201988
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- Power Life Sciences Inc.
22q11.2 Deletion Syndrome
Understanding of Psychotic Disorders in Children With 22q11.2DS
The study PremiCeS22 will investigate the prodromal signals at the onset of psychotic disorders of children with 22q11.2 deletion syndrome
- Trial name
- PremiCeS22 (NCT04639388)
- Testing
- neuropsychological testing, questionnaires and experimental tasks
- Where
- France
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Hôpital le Vinatier
Communication
Client Understanding, Expectations, and Intern Performance in Occupational Therapy
This study aims to investigate psychiatric clients' understanding of occupational therapy (OT), the reasonableness of their expectations regarding OT services, and OT interns' performance in Occupational Therapy Knowledge (OTK)…
- Trial name
- NCT07333794
- Testing
- Clinical Interview and Occupational Therapy Knowledge (OTK) Health Education Session
- Where
- Taiwan
- Volunteers
- 139 people
- Sponsor
- Chang Gung Memorial Hospital
Healthy Volunteers, Heart Failure
A Study Understanding How Much CDR132L Enters the Bloodstream After Injection Under the Skin Compared to Injection Into a Vein in Healthy Participants
This study is being done to understand how much of the medicine (CDR132L) enters the bloodstream after injection under the skin compared to injection into a vein in healthy people.
- Trial name
- NCT07656454
- Testing
- CDR132L (i.v.), CDR132L (s.c.)
- Where
- Germany
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Novo Nordisk A/S
Arrhythmia, Cardiomyopathy
Genetic Characterization of Patients With Arrhythmia-Induced Cardiomyopathy
The goal of this observational study is to learn about the genetic insights of arrhythmya-induced cardiomyopathy and its clinical prognosis. The main questions it aims to answer are: I.
- Conditions
- Arrhythmia, Cardiomyopathy, Arrhythmia-induced Cardiomyopathy (AiCM)
- Trial name
- UNCHAINED-I (NCT06896266)
- Where
- 4 sites in Spain
- Volunteers
- 109 people
- Sponsor
- Hospital Universitario 12 de Octubre
Dermatomyositis, Polymyositis
A Study to Understand How the Study Medicine Dazukibart Works in People With Idiopathic Inflammatory Myopathies
The purpose of this study is to understand how the study medicine, dazukibart, works in people with active idiopathic inflammatory myopathies (dermatomyositis [DM] or polymyositis [PM]).
- Trial name
- NCT06698796
- Testing
- Dazukibart
- Where
- 26 sites in United States, Argentina and 10 more
- Volunteers
- 211 people
- Sponsor
- Pfizer
Oesophageal Cancer
Understanding the Variation of Modern Endoscopic Ultrasound Use in Patients With Oesophageal Cancer (VALUE)
This is an observational trial that will look at patients undergoing endoscopic ultrasound (EUS) in patients with oesophageal cancer and to determine the proportion of cases in which EUS changes disease management in these…
- Trial name
- VALUE (NCT06440174)
- Testing
- endoscopic ultrasound
- Where
- 14 sites in United Kingdom
- Volunteers
- 160 people
- Sponsor
- University Hospital Southampton NHS Foundation Trust
Migraine, Migraine in Adolescence
Headache Education and Awareness vs. Daily Mindfulness Strategies - Understanding Pain
The goal of this study (supported by and included in the NIH HEAL Initiative: https://heal.nih.gov/) is to learn if a fully virtual study comparing two telehealth group interventions for adolescents with migraine is feasible and…
- Trial name
- HEADS-UP (NCT07513662)
- Testing
- BREATHE with Headache (BREATHE-HA), Enhanced Standard-of-Care: Headache Education
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- University of Colorado, Denver
Acute Lymphoblastic Leukemia, Lymphoblastic Lymphoma
Mobile Health Intervention to Support Oral Chemotherapy Adherence in Adolescents and Young Adults With Leukemia
This is a small-scale micro-randomized clinical trial of a new mobile just-in-time adaptive intervention (JITAI) designed to promote oral chemotherapy adherence in adolescents and young adults (AYA) with acute lymphoblastic…
- Trial name
- NCT03932903
- Testing
- ADAPTS (ADherence Assessments and Personalized Timely Support).
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Northwestern University
Systemic Lupus Erythematosus
Subgrouping SLE - a New Approach to Understand the Pathogenesis and Improve Treatment
The goal of this observational study is to investigate different phenotypes among patients with SLE and to compare with matched general population controls.
- Trial name
- SLEsubgroups (NCT07102030)
- Where
- Sweden
- Volunteers
- 900 people
- Sponsor
- Region Stockholm
Healthy Controls
Temporal Interference Stimulation for Social Cognition
The long-term goal of this project is to evaluate whether a procedure termed transcranial interference stimulation (tIS) may be useful in the future in the treatment of severe neuropsychiatric disorders such as schizophrenia.
- Trial name
- TISSC (NCT06607432)
- Testing
- Transcranial Interference Stimulation (tIS)
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Columbia University
Lung Carcinoma, Metastatic Lung Carcinoma
Novel INPUT Screening Tool to Improve Illness Understanding in Patients With Metastatic or Incurable Lung Cancer
This clinical trial compares the use of a new screening tool designed to evaluate patients' information needs, preferences, and illness understanding to the usual care to improve illness understanding in patients with lung cancer…
- Conditions
- Lung Carcinoma, Metastatic Lung Carcinoma, Stage IV Lung Cancer AJCC v8
- Trial name
- NCT06743308
- Testing
- Best Practice, Questionnaire Administration
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- M.D. Anderson Cancer Center
Aphasia
Criterion-learning Naming Treatment For Addressing Comprehension Deficits in Aphasia
Aphasia is a disorder of spoken and written language, most commonly following a stroke. It is estimated that between 2.5 and 4 million Americans are living with aphasia today.
- Trial name
- NCT07179458
- Testing
- Criterion-learning practice
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Albert Einstein Healthcare Network
Cutaneous Leihmaniasis
Study Comparing Several Drugs to Understand Which Work Against Cutaneous Leishmaniasis (CL)
MAMS4CL comprises a clinical trial with three embedded sub-studies designed to comprehensively evaluate the administered treatments and assess the impact of CL treatment on patients and the healthcare system.
- Trial name
- NCT07463040
- Testing
- Sodium Stibogluconate (SSG), Miltefosine, Miltefosine + Paromomycin
- Where
- 3 sites in Ethiopia
- Volunteers
- 900 people
- Sponsor
- Institute of Tropical Medicine, Belgium