Clinical trials: Comprehensive Care
Hypertensive Disorders of Pregnancy, Chronic Hypertension in Pregnancy
MH-Rx Study (Baby on Board: Check-in on You, Your Medication, & Your Blood Pressure)
This randomized controlled trial will evaluate whether adding Community Health Worker (CHW)/Social Worker (SW)-led support for non-medical health related needs (NMHRN) and clinician-led Medication Therapy Management (MTM) to…
- Conditions
- Hypertensive Disorders of Pregnancy, Chronic Hypertension in Pregnancy, Gestational Hypertension
- Trial name
- NCT07842341
- Testing
- Community Health Worker (CHW)/Social Worker (SW)-led non-medical health related needs (NMHRN) intervention + Clinician-Led Medication Therapy Management (MTM) with remote blood pressure monitoring, Active Comparator (Control group)
- Where
- United States
- Volunteers
- 158 people
- Sponsor
- Texas Southern University
Acute Heart Failure
Early and Comprehensive Care Bundle in Elderly for Acute Heart Failure: a Stepped Wedge Cluster Randomized Trial
This is a prospective multicentre (N=15), stepped-wedge randomized trial that aims to evaluate the benefit of a protocolised comprehensive care bundle for early management of acute heart failure in the ED.
- Trial name
- ELISABETH (NCT03683212)
- Testing
- Early intensive care bundle
- Where
- France
- Volunteers
- 503 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Surgery, Aging
Preparing Older Adults for Major Surgery With Preoperative Comprehensive Geriatric Assessments
The researchers will conduct observations, interviews, and focus groups with clinicians, staff and patients of the Perioperative Optimization of Senior Health (POSH) clinic, which conducts preoperative comprehensive geriatric…
- Conditions
- Surgery, Aging, Health Care Utilization, Frailty
- Trial name
- NCT06184919
- Testing
- Process Mapping: Observations, Process Mapping: Interviews, Process Mapping: Focus Group
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Wisconsin, Madison
Medicare Patients, High Risk of Hospitalizations
Comprehensive Care Physician: Integrated Inpatient and Outpatient Care for Patients at High Risk of Hospitalization
The investigators propose an innovative new model of care in which patients identified to be at high risk of hospitalization are offered care by a physician who will direct their care both in the hospital and in clinic but is…
- Trial name
- CCP (NCT01929005)
- Testing
- Comprehensive Care
- Where
- United States
- Volunteers
- 2,008 people
- Sponsor
- University of Chicago
Hypertension, Hyperglycemia
Prospective Exploratory Study on the Comprehensive Application Effectiveness of Exercise Prescription Decision Support Tools in the Management of Patients With "Four Highs" (Hypertension, Hyperglycemia, Hyperlipidemia, Hyperuricemia)
This study conducted a six-month exploratory clinical trial to evaluate the impact of an exercise prescription mini-program, based on the "Exercise Guidelines for the 'Four Highs'", on the physical activity levels and related…
- Conditions
- Hypertension, Hyperglycemia, Hyperlipidemia, Hyperuricemia
- Trial name
- NCT07400549
- Testing
- Enhanced Mini-Program Intervention, Enhanced Control
- Where
- China
- Volunteers
- 100 people
- Sponsor
- China National Center for Cardiovascular Diseases
Autism Spectrum Disorders
Pilot Study on Collaborative, Comprehensive, Multidimensional and Quality of Life Tools for Priority Definition, Shared Decision Making, Outcome Evaluation and Quality of Care Improvement in ASD Individuals and Programs in the Real World.
ASD is a very complex and lifelong disorder. Patients' functioning is influenced by multiple factors, including treatments, inclusion and life contexts.
- Trial name
- ASD Outcome (NCT07393152)
- Testing
- DD-CGAS (Wagner et al. 2007), Pediatric Quality of Life Inventory (PedsQL)., Child and Adolescent Needs and Strengths (CANS) (Lyons 2022)
- Where
- 3 sites in Italy
- Volunteers
- 400 people
- Sponsor
- Antonella Costantino
Surgical Complications, Sarcoma
Application of a Comprehensive Protocol Aimed at Reducing the Risk of Complications After Surgery for Sarcoma. Interventions Before, During and After Surgery for Known and Presumed Risk Factors Compared to Standard of Care in a Total of 300 Patients.
Sarcoma is a rare malignancy made up by several sub types that can occur throughout the body. Roughly speaking, the division into soft tissue sarcoma (STS) and skeletal sarcoma (SS) can be made.
- Trial name
- NCT06968884
- Testing
- Protocol based, Control (Standard treatment)
- Where
- Sweden
- Volunteers
- 300 people
- Sponsor
- Region Stockholm
Osteoporosis, Frailty
Spitex-SpiTal-Autonomie-Reha-Kraft
The primary purpose of this study is to test if the STARK comprehensive autonomy health care package improves lower extremity function over time at 6 weeks, 3, 6 and 12 months after hip or pelvis fracture compared to the standard…
- Conditions
- Osteoporosis, Frailty, Hip Fractures
- Trial name
- STARK (NCT03154684)
- Testing
- STARK intervention, Standard of Care
- Where
- Switzerland
- Volunteers
- 5 people
- Sponsor
- University of Zurich
Bladder Cancer, Radical Cystectomy
Comprehensive Optimization At-time of Radical Cystectomy Intervention
The proposed study is aimed at a comprehensive optimization at-time of radical cystectomy (COARC) intervention that focuses on patient optimization throughout the perioperative continuum, from the pre-operative setting to the…
- Trial name
- COARC (NCT05714826)
- Testing
- Preop Intervention and Monitored Recovery, Usual Care
- Sponsor
- University of Texas Southwestern Medical Center
Depressive Disorder, Major
Study to Evaluate the Efficacy and Safety of 3 Fixed Doses of Intranasal Esketamine in Addition to Comprehensive Standard of Care for the Rapid Reduction of the Symptoms of Major Depressive Disorder, Including Suicidal Ideation, in Pediatric Participants Assessed to be at Imminent Risk for Suicide
The purpose of this study is to assess the efficacy of a single (first) dose of 3 fixed doses of intranasal esketamine {28 milligram (mg), 56 mg, and 84 mg} compared with psychoactive placebo (oral midazolam) in rapidly reducing…
- Trial name
- NCT03185819
- Testing
- Midazolam, Esketamine
- Where
- 51 sites in United States, Belgium and 7 more
- Volunteers
- 147 people
- Sponsor
- Janssen Research & Development, LLC
Urologic Diseases, Urinary Tract Infections
Effect of Comprehensive Spa Care on Kidney and Urological Conditions: A Clinical Study in Adult Patients
This is a single-arm, pretest-posttest study evaluating the effects of a 21-day comprehensive spa care (Komplexní lázeňská léčebně rehabilitační péče, KLP) on patients with nephrological and urological conditions treated at a spa…
- Conditions
- Urologic Diseases, Urinary Tract Infections, Nephrolithiasis, Nephrocalcinosis
- Trial name
- Uro-Nefro (NCT07435844)
- Testing
- Comprehensive Spa Care, Exercise Therapy, Dietotherapy
- Where
- Czechia
- Volunteers
- 150 people
- Sponsor
- Institute of Spa and Balneology, public research institution
Older People, Non-Communicable Chronic Diseases
A Personalized Prevention Program (PPP) Based on the Comprehensive Geriatric Assessment (CGA) for the Prevention of Multidimensional Frailty Related to Non-communicable Chronic Diseases (NCDs) in Older People
Non-Communicable Diseases (NCDs) can accelerated the aging process and increase the frailty condition The Comprehensive Geriatric Assessment (CGA) is the gold standard in the geriatric clinical context Recently, in Italy the…
- Trial name
- PrimaCare_P3 (NCT06224556)
- Testing
- Brief-MPI assessment (based on the Comprehensive Geriatric Assessment); Personalized Prevention Program
- Where
- 4 sites in Italy
- Volunteers
- 1,216 people
- Sponsor
- Alberto Pilotto
Breastfeeding, Exclusive
MILC: A Comprehensive Mobile Application That Addresses the Breastfeeding Challenges of Low-income Hispanic Mothers
The innovative platform MILC is designed to provide an integrated and comprehensive professional and social support network with personalized breastfeeding (BF) education to target exclusive breastfeeding (EBF) and any BF…
- Trial name
- MILC (NCT06520696)
- Testing
- MILC application, Usual care
- Where
- 3 sites in United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Benten Technologies, Inc.
Type 2 Diabetes Mellitus
Preventive Effectiveness of Primary Care Physician-led CGM-supported Comprehensive Intervention on Cardio-metabolic-immune Diseases in Community Patients With Type 2 Diabetes (Community Diabetes Control Project)
This community-based trial evaluates whether primary care physicians, equipped with continuous glucose monitoring (CGM) and trained under a standardized protocol with specialist backup, can improve diabetes outcomes through…
- Trial name
- CDCP (NCT07885904)
- Testing
- comprehensive intervention
- Where
- China
- Volunteers
- 15,400 people
- Sponsor
- Xiangya Hospital of Central South University
Palliative Care, Primary Care
Introducing the Palliative Care Comprehensive Tool in Family Medicine
The purpose of this study is to pilot the introduction of a newly developed palliative care tool to clinicians in a family health team.
- Conditions
- Palliative Care, Primary Care, Satisfaction
- Trial name
- NCT03267706
- Testing
- Palliative Care Comprehensive Tool
- Where
- Canada
- Volunteers
- 149 people
- Sponsor
- McMaster University
Alzheimer Disease, Dementia
Care Coordination System for People With Dementia
Dementia, a chronic disease of aging, is characterized by progressive cognitive decline that interferes with independent functioning.
- Conditions
- Alzheimer Disease, Dementia, Dementia Alzheimers
- Trial name
- NCT04308512
- Testing
- Active Nili device, Passive Nili system
- Where
- United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Bijan Najafi, PhD
COPD
Sputum-guided Treatment With Comprehensive Care Management in COPD - A Randomized-controlled Trial
Chronic obstructive pulmonary disease (COPD) is a lung condition affecting 1 in 6 Canadians and does not have a cure. Flare-ups of COPD are the most common reason someone goes to hospital in Canada.
- Trial name
- STRIVE (NCT04890938)
- Testing
- Sputum-guided management and comprehensive care management, Usual Care
- Where
- 2 sites in Canada
- Volunteers
- 128 people
- Sponsor
- McMaster University
Hypertension
Study of a Comprehensive Intelligent Hypertension managEment SyStem
This cluster randomized controlled trial aims to evaluate the efficacy of a comprehensive intelligent hypertension management system (CHESS) in blood pressure lowering in primary health care (PHC) settings of China.
- Trial name
- CHESS (NCT05605418)
- Testing
- CHESS intervention
- Where
- China
- Volunteers
- 1,666 people
- Sponsor
- China National Center for Cardiovascular Diseases
Frailty
SOLAR- Frailty Screening and Multidisciplinary Assessment of Older Adults in the Emergency Department
SOLAR is a randomised control trial exploring the role of Comprehensive Geriatric Assessment (CGA) in older adults who screen positive for frailty based on the Identification of Seniors at Risk (ISAR) tool the the Emergency…
- Trial name
- SOLAR (NCT04629690)
- Testing
- SOLAR
- Where
- Ireland
- Volunteers
- 229 people
- Sponsor
- University of Limerick
Geriatrics, Comprehensive Geriatric Assessment
Effectiveness of CGA on QoL in Older Patients With Cancer Receiving Systemic Therapy
The G-oncoCOACH study aims to evaluate the effectiveness of the Comprehensive Geriatric Assessment (CGA) process coordinated by a geriatric team in combination with intensive patient coaching compared to the current standard of…
- Trial name
- G-oncoCOACH (NCT04069962)
- Testing
- CGA coordination by geriatric team including intensive patient coaching and follow-up
- Where
- Belgium
- Volunteers
- 204 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven