Clinical trials: Compression
Carpal Tunnel Syndrome
Splinting After Mini-Open Carpal Tunnel Release
The purpose of this study is to determine if any difference exists among 3 different postoperative splinting regimens- no splint, removable splint, and plaster non-removable splint- following mini-open carpal tunnel release (CTR)…
- Trial name
- NCT02885701
- Testing
- No Splint, Removable Splint, Non-removable Splint
- Volunteers
- 249 people, healthy volunteers welcome
- Sponsor
- Anthony L. Logli
Varicose Ulcer
Negative Pressure Vs. Compression in Venous Ulcers
This study randomises patients with venous leg ulcers, to be managed either using conventional compression bandages or a bridged vacuum assisted closure system under compression.
- Trial name
- NCT03688841
- Testing
- Bridged V.A.C.® with compression therapy, Conventional Compression Therapy
- Where
- Ireland
- Volunteers
- 50 people
- Sponsor
- Western Vascular Institute, Ireland
Asthma
Effects of Compression Stockings in Asthma Symptoms at Night
Nocturnal worsening of asthma is common. It is characterized by overnight exacerbation of asthma symptoms such as shortness of breath, chest tightness, coughing, and wheezing, increased need of asthma medications and airway…
- Trial name
- NCT03303586
- Testing
- Compression Stockings, Control
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University Health Network, Toronto
Chronic Venous Insufficiency
Efficacy of Active Versus Passive Methods in Chronic Venous Insufficiency
The aim of our study was to compare the effectiveness of active and passive practices in patients with CVI.
- Trial name
- NCT05383469
- Testing
- Exercise Training, Massage, Neuromuscular Electrical Stimulation
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people
- Sponsor
- Istanbul University - Cerrahpasa
Peripheral Artery Disease
Intermittent Pneumatic Compression With and Without Exercise to Improve Functioning in Peripheral Artery Disease
The INTERCEDE randomized trial will establish whether six-months of intermittent pneumatic compression combined with walking exercise improves walking endurance at six-month follow-up, compared to walking exercise + sham…
- Trial name
- INTERCEDE (NCT03871075)
- Testing
- intermittent pneumatic compression, exercise, Health Education
- Where
- 4 sites in United States
- Volunteers
- 211 people
- Sponsor
- Northwestern University
Fracture of Neck of Femur
Medial Enhancement Technique for the Treatment of Old Femoral Neck Fractures
A prospective, multi-center, randomized controlled study was conducted to validate the safety and effectiveness of employing the medial augmentation technique (incorporating the dynamic condylar screw and medial support plate)…
- Trial name
- NCT06713031
- Testing
- cannulated compression screws + iliac bone graft, DCS + medial support plate + iliac bone graft
- Where
- China
- Volunteers
- 400 people
- Sponsor
- Chinese PLA General Hospital
Carpal Tunnel Syndrome, Patient Satisfaction
Postoperative Care After Carpal Tunnel Release Using Short Educational Videos
The goal of this clinical trial is to learn if a patient-directed postoperative care program, using short educational videos, can improve patient satisfaction and reduce healthcare resource utilization in patients undergoing…
- Trial name
- VIDEO (NCT06647719)
- Testing
- Educational Videos
- Where
- United States
- Volunteers
- 84 people
- Sponsor
- Carilion Clinic
Carpal Tunnel Syndrome (CTS)
Open vs. Ultrasound-Guided Carpal Tunnel Release
Carpal Tunnel Syndrome (CTS) is the most prevalent entrapment neuropathy. Open Surgical Carpal Tunnel Release (OSCTR) remains the gold standard, while minimally invasive Ultrasound-Guided Carpal Tunnel Release (USGCTR) offers…
- Trial name
- NCT07814547
- Testing
- Open Surgical Carpal Tunnel Release (OSCTR), Ultrasound-Guided Carpal Tunnel Release (USGCTR)
- Where
- 2 sites in Austria
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- AUVA General Trauma Hospital Salzburg
Rectal Cancer, Sigmoid Cancer
Adaptive Anastomosis for Anterior Resection in Sigmoid and Proximal Rectal Cancer or Premalignant Lesions
Background: Anastomotic leakage (AL) after colorectal surgery remains a significant challenge, associated with increased morbidity, mortality, poor oncological outcomes, and reduced quality of life.
- Conditions
- Rectal Cancer, Sigmoid Cancer, Premalignant Lesion, Colorectal Cancer
- Trial name
- ADAPT (NCT07056374)
- Testing
- C-REX RectoAid Cath
- Where
- Netherlands
- Volunteers
- 165 people
- Sponsor
- Amsterdam UMC, location VUmc
Chronic Edema, Lymphedema
Boosted Compression for Lower Limb Chronic Edema
Patients: Patients targeted in this proposal comprise individuals afflicted by chronic edema/lymphedema of the lower limbs. Intervention: The intervention entails the incorporation of boosted compression alongside standard care…
- Trial name
- BECOME (NCT07708662)
- Testing
- Conservative edema treatment (complex decongestive therapy), Conservative edema treatment with boosted compression therapy
- Where
- 4 sites in Belgium
- Volunteers
- 160 people
- Sponsor
- Universiteit Antwerpen
Neonatal Resuscitation, Airway Management
Success of Laryngeal Mask Airway (LMA) Insertion During Continuous Chest Compressions in Neonatal Resuscitation: A Randomized Crossover Simulation Study
The purpose of this study is to evaluate the time required for laryngeal mask airway (LMA) insertion, first-attempt success rates, and airway sealing quality (air leak) during neonatal resuscitation with and without interrupting…
- Conditions
- Neonatal Resuscitation, Airway Management, Asphyxia Neonatorum, Cardiopulmonary Resuscitation (CPR)
- Trial name
- NCT07681960
- Testing
- Size 1 ProSeal™ LMA
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Kahramanmaras Sutcu Imam University
Bone Metastases
Study of Denosumab vs. Zoledronic Acid to Treat Bone Metastases in Subjects With Advanced Cancer or Multiple Myeloma.
The purpose of this study is to determine if denosumab is non-inferior to zoledronic acid (Zometa®) in the treatment of bone metastases (lytic bone lesions from multiple myeloma) in subjects with advanced cancer and multiple…
- Trial name
- NCT00330759
- Testing
- Denosumab, Zoledronic Acid
- Volunteers
- 1,779 people
- Sponsor
- Amgen
Lymphocele
Use of Compression Bandages in the Prevention of Post-mastectomy Lymphoceles
Lymphocele secondary to a mastectomy whether or not associated with a lymph node procedure (sentinel lymph node or axillary dissection) is an almost systematic consequence observed in the postoperative situation in this type of…
- Trial name
- BANDOCELE (NCT04819542)
- Testing
- Bandage, No bandage
- Where
- France
- Volunteers
- 84 people
- Sponsor
- University Hospital, Toulouse
Primary Osteoarthritis Patients Scheduled for Total Knee Replacement Surgery
Cold and Compression Post TKA
The purpose of this study is to compare pain score (Patient-Reported Outcomes Measurement Information System: PROMIS NRS Pain Subscale) between the control and cold/compression groups pre-surgically, daily after surgery for 14…
- Trial name
- NCT07023185
- Testing
- Cold and Compression, SOC (Standard of care)
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Ochsner Health System
Lymphedema
Therapeutical Assessment of Compression Armsleeves for Lymphatic Indications
Examination of therapeutical effects of different types of armsleeves in treating lymphatic diseases after breast cancer surgery during maintenance phase 1. thesis: all types should be equal regarding volume reduction 2.
- Trial name
- BF09-PH-01 (NCT01318785)
- Testing
- Compression Armsleeves
- Where
- 4 sites in Austria, Belgium and 2 more
- Volunteers
- 40 people
- Sponsor
- University Medicine Greifswald
Evaluable
Effects of Continuous Anterior Chest Compression
The aim is to test the physiological effects of continuous anterior chest compression in patients with severe to moderate ARDS.
- Trial name
- StrapVent (NCT05876468)
- Testing
- Continuous anterior chest compression
- Where
- France
- Volunteers
- 20 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Urothelial Carcinoma, Advanced Solid Tumors
Compression Stockings to Prevent Peripheral Neuropathy Caused by Antibody-Drug Conjugates in Urothelial Carcinoma Patients
This multicenter, prospective phase II clinical trial aims to evaluate the efficacy and safety of medical compression stockings in preventing peripheral neuropathy induced by antibody-drug conjugates (ADCs) containing monomethyl…
- Conditions
- Urothelial Carcinoma, Advanced Solid Tumors, Chemotherapy-Induced Peripheral Neuropathy, Antibody-drug Conjugates
- Trial name
- NCT07164950
- Testing
- Medical-grade compression stocking
- Where
- China
- Volunteers
- 58 people
- Sponsor
- Sheng Zhang
Stroke, Complex Regional Pain Syndrome
Contrast Compression Therapy for Post-Stroke Complex Regional Pain Syndrome
This study aims to evaluate the effectiveness of contrast compression therapy as an adjunct to conventional rehabilitation in patients diagnosed with complex regional pain syndrome (CRPS) following stroke.
- Conditions
- Stroke, Complex Regional Pain Syndrome, Hemiplegia
- Trial name
- NCT07062913
- Testing
- Conventional Rehabilitation, Contrast Compression Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people
- Sponsor
- Meltem Gunes Akinci
Obstructive Sleep Apnea Syndrome
Osteopathy and Obstructive Sleep Apnea Syndrome II
The main objective is to evaluate an osteopathic compression of pterygopalatine node in healthy subjects and patients suffering from obstructive apnea syndrome (OSA).
- Trial name
- OSTEOSAOSII (NCT01822743)
- Testing
- Osteopathic manipulative treatment
- Where
- France
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Radiculopathy, Cervical, Myelopathy Cervical
Cervical Arthroplasty Cost Effectiveness Study (CACES)
To date, no consensus exists on which anterior surgical technique is more cost-effective to treat cervical degenerative disc disease (CDDD).
- Conditions
- Radiculopathy, Cervical, Myelopathy Cervical, Myelopathy, Compressive, Radiculopathy, Cervical Region
- Trial name
- CACES (NCT04623593)
- Testing
- ACDF, ACDA
- Where
- Netherlands
- Volunteers
- 198 people
- Sponsor
- Valérie Schuermans
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