Clinical trials: Compression Fracture, active
Kyphoplasty, Vertebroplasty
A Prospective, Single-center, Observational Clinical Outcomes Study for Vertebral Compression Fractures Treated With the OsteoPearl Biological Allograft Implants
The primary objective of this observational study is to evaluate fracture stability through longitudinal assessment of subject-reported pain following treatment with the OsteoPearl Biological Allograft in men and women aged ≥50…
- Conditions
- Kyphoplasty, Vertebroplasty, Vertebral Compression Fracture, Allograft
- Trial name
- PEARL ONE (NCT07561489)
- Testing
- Allograft
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Lenoss Medical
BKP, Osteoporotic Vertebral Compression Fracture
Randomized Controlled Trial of Internal Fixation Reconstruction With Stent Screw in the Treatment of Kummell's Disease
This study is a multicenter, prospective, double-blind, randomized controlled trial using a parallel two-arm design to investigate whether the postoperative 6-month quality of life, vertebral stability, complication of patients…
- Conditions
- BKP, Osteoporotic Vertebral Compression Fracture, Kummell's Disease, Stent-screw-assisted Internal Fixation
- Trial name
- NCT06093087
- Testing
- SAIF, BKP
- Volunteers
- 70 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Osteoporotic Vertebral Compression Fractures, Vertebroplasty
Standardized Study Protocol of Percutaneous Vertebroplasty Based on Pedicle Nine-Grid Zoning Method
The goal of this clinical trial is to verify the safety and efficacy of the pedicle "Nine-grid Zoning Method" in assisting percutaneous vertebroplasty (PVP) for the treatment of lumbar osteoporotic vertebral compression fractures…
- Trial name
- NCT07616583
- Testing
- Nine-grid Area Division Method Assisted PVP, Traditional Standard Percutaneous Vertebroplasty (PVP)
- Where
- China
- Volunteers
- 68 people
- Sponsor
- Beijing Friendship Hospital
Vertebral Compression Fracture, Compression Fracture
STAND - Study of the AGN1 LOEP SV Kit Compared to PMMA in Patients With Vertebral Compression Fractures
This is a multicenter, single-blinded, randomized controlled clinical trial evaluating the safety and efficacy of the AGN1 LOEP SV Kit for the treatment of painful vertebral compression fragility fractures (VCFs).
- Conditions
- Vertebral Compression Fracture, Compression Fracture, Vertebral Compression
- Trial name
- NCT04835428
- Testing
- Treatment Group: AGN1 LOEP SV Kit, Control Group: PMMA bone cement
- Where
- 12 sites in United States
- Volunteers
- 408 people
- Sponsor
- AgNovos Healthcare, LLC
Vertebral Compression Fractures, Pathological Fracture
Prospective Evaluation of Therapeutic Combination in Treating Vertebral Compression Fractures
The purpose of this study is to collect clinical and radiographic outcomes in patients undergoing vertebroplasty procedures for the treatment of osteoporotic or pathological fractures of the vertebral body to understand the role…
- Conditions
- Vertebral Compression Fractures, Pathological Fracture, Facet Joint Arthropathy
- Trial name
- PROTECT (NCT06670404)
- Testing
- Vertebroplasty
- Where
- Switzerland
- Volunteers
- 130 people
- Sponsor
- Prof Nicolas Theumann
Vertebral Compression Fracture
Investigating Bone Cement With or Without Inossia® Cement Softener for Vertebral Compression Fractures
The overall purpose of conducting this study is to evaluate the safety and efficacy of V-Flex and V-Steady for augmentation of osteoporotic vertebral compression fractures and to verify that adding a cement softener into a PMMA…
- Trial name
- SOFTBONE (NCT05676320)
- Testing
- V-Flex, V-Steady
- Where
- 9 sites in Canada, Germany and 2 more
- Volunteers
- 203 people
- Sponsor
- Inossia AB
Anterior Mandibular Fracture
Evaluation of Condylar Position After Anterior Mandibular Fracture Fixation Using Plates Versus Headless Compression Screws
This study compares two methods for fixing fractures of the front part of the lower jaw: Conventional plates and screws Headless compression screws Patients are randomly assigned to one of the two treatment groups.
- Trial name
- fracture (NCT07826403)
- Testing
- headless compression screw, conventional plates
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Cairo University
Fracture of Neck of Femur
Medial Enhancement Technique for the Treatment of Old Femoral Neck Fractures
A prospective, multi-center, randomized controlled study was conducted to validate the safety and effectiveness of employing the medial augmentation technique (incorporating the dynamic condylar screw and medial support plate)…
- Trial name
- NCT06713031
- Testing
- cannulated compression screws + iliac bone graft, DCS + medial support plate + iliac bone graft
- Where
- China
- Volunteers
- 400 people
- Sponsor
- Chinese PLA General Hospital
Thoracolumbar Compression Fractures
Effect of 60-day Peripheral Nerve Stimulation (PNS) in Alleviating Pain and Improving Function After Acute Thoracolumbar Compression Fracture
The purpose of this study is to track and investigate the outcomes of female patients with acute thoracolumbar compression fractures, focusing on pain management and functional improvement.
- Trial name
- NCT07079865
- Testing
- SPRINT PNS modulation system
- Where
- 4 sites in United States
- Volunteers
- 15 people
- Sponsor
- Saint Peters University Hospital
Medial Malleolus Fracture, Lisfranc Injury
Performance and Safety Evaluation of Inion CompressOn Screw in Foot and Ankle Surgeries. PMCF Investigation
The study in question is a post market clinical follow up (PMCF) study to evaluate the safety and performance of bioabsorbable headless compression screw Inion CompressOn in selected fracture, osteotomy and arthrodeses operations…
- Conditions
- Medial Malleolus Fracture, Lisfranc Injury, Lisfranc Fracture, Talus Fracture
- Trial name
- NCT05555459
- Testing
- Operation
- Where
- Finland
- Volunteers
- 125 people
- Sponsor
- Inion Oy
Clinical Decision Support System
Development and Application of a Clinical Decision Support System for Exercise Rehabilitation in Patients With Osteoporotic Vertebral Compression Fractures
This study aims to develop a clinical decision support system for exercise rehabilitation in patients with osteoporotic vertebral compression fractures, based on evidence-based recommendations for postoperative exercise…
- Trial name
- NCT07623304
- Testing
- Decision Support System: A clinical decision support system for exercise rehabilitation in patients with osteoporotic vertebral compression fractures, Basic Postoperative Care, Conventional Postoperative Care
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Jiawei Jiang
Ankle Fracture, Ankle Arthrodesis
Compression Therapy for Swelling Management Following Ankle Injury
After an injury or undergoing foot/ankle surgery, patients often experience swelling in the injured area. Under current standard of care, plaster casts are removed at six weeks and patients are put in a walking boot.
- Trial name
- NCT06772649
- Testing
- Compression sleeve
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- Nova Scotia Health Authority
Traumatic Vertebral Fractures, Compression Fractures of the Spine
Comparison of Three Treatment Strategies for Traumatic AO Type A1 Vertebral Fractures
This retrospective study evaluates three different treatment approaches used for traumatic AO Spine Type A1 (A1) vertebral fractures: orthopedic bracing, percutaneous vertebroplasty, and spinal arthrodesis.
- Conditions
- Traumatic Vertebral Fractures, Compression Fractures of the Spine, AO Type A1 Vertebral Fracture, Spinal Trauma
- Trial name
- TRAUMA-A1 (NCT07471568)
- Where
- Spain
- Volunteers
- 146 people
- Sponsor
- University of Valencia
Osteoporosis, Osteoporotic Vertebral Compression Fractures
Safety and Efficacy Clinical Trial of the Vessel-X® Bone Filling Container System
Osteoporotic vertebral compression fractures (OVCFs) are a common and serious complication of osteoporosis, particularly among elderly and postmenopausal patients.
- Trial name
- CMT-VX (NCT07665424)
- Testing
- CMT Vessel-X® Bone Filling Container System, CMT Manual Orthopedic Surgical Instruments
- Where
- 2 sites in Taiwan
- Volunteers
- 146 people
- Sponsor
- Juin-Hong Cherng
Fracture of Femoral Neck
Clinical Study of a Novel Sliding Compression Locking Plate in the Treatment of Fresh Femoral Neck Fractures
To verify the safety and efficacy of sliding compression locking plates in the treatment of fresh femoral neck fractures
- Trial name
- NCT06713291
- Testing
- Sliding compression locking plate, Three cannulated compression screws
- Where
- 3 sites in China
- Volunteers
- 1,150 people
- Sponsor
- Chinese PLA General Hospital
Thoracolumbar Low-energy Vertebral Compression Fractures
Large-Scale Evaluation of a Clinical Decision Tree for the Management of Low-Energy Thoracic and Lumbar Vertebral Compression Fractures.
Percutaneous vertebroplasty is widely used for low-energy vertebral compression fractures, but its clinical benefits remain debated.
- Trial name
- PALMTREE (NCT07706439)
- Where
- France
- Volunteers
- 400 people
- Sponsor
- University Hospital, Grenoble
Vertebral Compression Fracture
Vertebral Augmentation Using VCFix Spinal System in Stand-alone Configuration
This study will review the safety and possibility of the VCFix Spinal System. This is a proof-of-concept study and an initial review of the surgical procedure and how well the VCFix device works, to who that the VCFix is safe and…
- Trial name
- NCT07259811
- Testing
- VCFix Spinal System in stand-alone configuration
- Where
- 2 sites in Germany
- Volunteers
- 10 people
- Sponsor
- Amber Implants B.V.
Osteoporotic Vertebral Compression Fractures
Continuous Mobility and Physical Activity in Vertebroplasty vs Sham for Osteoporotic Vertebral Fracture
The aim of this clinical trial is to determine if vertebroplasty is an effective treatment for acute, painful vertebral fractures due to osteoporosis.
- Trial name
- VOPE2 COMPAS (NCT06776003)
- Testing
- Vertebroplasty
- Where
- Denmark
- Volunteers
- 64 people
- Sponsor
- Spine Centre of Southern Denmark
Pain
Cannulated Bone Bolt® Screw System Versus Standard Cannulated Screw System Fixation for Pelvic Fractures
The investigators aim is to determine if the cannulated Bone Bolt® screw system will provide improved post-operative pain control as compared to standard cannulated screw system fixation for the operative treatment of LC1…
- Trial name
- NCT07209280
- Testing
- Cannulated Bone Bolt® Screw System, Standard Cannulated Screw System
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Utah
Thoracolumbar Compression Fractures
Short Segment Versus Long Segment Transpedicular Screw Fixation in the Correction and Preservation of AO-Type B Thoracolumbar Fracture Alignment: A Comparative Study
To compare the radiological, clinical and functional outcomes of short-segment versus long-segment transpediclular screw fixation in patients with thoracolumbar fractures AO-type B.
- Trial name
- NCT07777653
- Testing
- Short Segment Versus Long Segment Transpedicular Screw Fixation in the Correction and Preservation of AO-Type B Thoracolumbar Fracture Alignment: A Comparative Study
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Assiut University