Clinical trials: Compulsion
Smoking Cessation, Smoking Behaviors
ACT Lung Health Intervention: Phase Two
This study aims to test a counseling and educational program designed to improve lung health through smoking cessation for Chinese and Korean American smokers at high risk for lung cancer.
- Conditions
- Smoking Cessation, Smoking Behaviors, Smoking, Tobacco, Smoking, Cigarette
- Trial name
- NCT06945120
- Testing
- ACT Lung Health Intervention
- Where
- 2 sites in United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Dana-Farber Cancer Institute
Addiction, Risk Reduction Behaviour
The Effectiveness of Skill-Based HIV Psychoeducation in IV-Drug Abuser for Reducing High-risk Behavior
The Effectiveness of Skill-Based HIV Psychoeducation in IV-Drug abuser for reducing high-risk behavior
- Trial name
- NCT00935103
- Testing
- Psychoeducation
- Volunteers
- 120 people
- Sponsor
- Iran University of Medical Sciences
Drug Abuse
The Effects of Expectation on Natural and Drug -Induced Rewards
Background: Environmental cues frequently induce expectancies in individuals that may strongly influence the actual experience associated with the cue.
- Trial name
- NCT01036230
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- National Institute on Drug Abuse (NIDA)
Behavior, Addictive, College Student
The Experience of Short Video Addiction Among College Students
This qualitative study aims to explore the experience of short-video addiction among college students using a directed content analysis approach grounded in the integrated framework of the Stimulus-Organism-Response (S-O-R)…
- Trial name
- NCT07574021
- Testing
- Semistructured interview
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Sun Yat-sen University
Methamphetamine Abuse, Methamphetamine-dependence
Clinical Trial of High Dose Lisdexamfetamine and Contingency Management in MA Users
The goal of this clinical trial is to learn if administering a high dose stimulant with Contingency Management reduces days of use in adults who use methamphetamine better than the usual treatment provided by the clinic.
- Conditions
- Methamphetamine Abuse, Methamphetamine-dependence, Addiction, Substance, Addiction
- Trial name
- NCT05854667
- Testing
- Treatment as Usual plus lisdexamfetamine (LDX-01), Treatment as Usual plus lisdexamfetamine (LDX-01) plus Contingency Management
- Where
- 4 sites in Canada
- Volunteers
- 440 people, healthy volunteers welcome
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Substance-Related Disorders
Addictology Expert Patients' Fields of Intervention
Although there are many publications concerning the benefit of the interventions of the self-help movements and peer health mediators in psychiatry, no studies have described the intervention specific to patients with expertise…
- Trial name
- HAPEX (NCT04458987)
- Testing
- Expert patient in addictology
- Where
- France
- Volunteers
- 69 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Substance Use Disorders, Posttraumatic Stress Disorder
Written Exposure Therapy for Veterans With SUD and PTSD
The proposed project will evaluate the efficacy of written exposure therapy (WET) among Veterans engaged in substance use disorder (SUD) treatment, who present with co-occurring posttraumatic stress disorder (PTSD).
- Trial name
- WET (NCT05327504)
- Testing
- Written Exposure Therapy, Neutral Topic Writing
- Where
- United States
- Volunteers
- 170 people
- Sponsor
- VA Office of Research and Development
Stimulant Dependence
Mindfulness Based Relapse Prevention for Stimulant Users
The broad, long-term objective of the current research is to improve treatment for stimulant use disorders by augmenting traditional relapse prevention therapy with innovative meditation-based strategies to promote affect…
- Trial name
- MBRP (NCT01094223)
- Testing
- Mindfulness Based Relapse Prevention, Health Education
- Where
- United States
- Volunteers
- 62 people
- Sponsor
- University of California, Los Angeles
Alcohol Use Disorder (AUD)
AAT-App Outpatient Trial
Cognitive biases contribute to the difficulty experienced by heavy drinkers wishing to reduce their alcohol use. Recent interventions designed to reduce cognitive biases demonstrate efficacy for Approach Bias Modification (ApBM).
- Trial name
- AAT-App (NCT05120856)
- Testing
- AAT-App, Minimal AAT-App
- Where
- 6 sites in Australia
- Volunteers
- 82 people
- Sponsor
- Turning Point
Addiction
Linking fMRI to Mobile Technologies in Addiction Research: Pathophysiology of Executive Deficits, Craving and Substance Use
120 individuals with alcohol, cannabis or nicotine dependence as well as healthy controls will be administered a whole-brain imaging exam.
- Trial name
- MobiCogIm (NCT02334956)
- Testing
- Brain MRI
- Where
- 2 sites in France
- Volunteers
- 107 people, healthy volunteers welcome
- Sponsor
- University Hospital, Bordeaux
Smoking, Nicotine
Impact of Daridorexant on Sleep, Daytime Alertness, and Smoking
Tobacco use is the leading cause of preventable death in the U.S., with 480,000 deaths per year and 7.7 million deaths globally.
- Conditions
- Smoking, Nicotine, Tobacco, Addiction
- Trial name
- NCT07328594
- Testing
- Daridorexant 50 mg
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- Legacy Health System
Methamphetamine Use Disorder
Psilocybin for Methamphetamine Addiction
The primary purpose of this study is to preliminarily determine if the use of psilocybin to promote abstinence from methamphetamine is feasible and well tolerated in populations such as those found in Northern Louisiana.
- Trial name
- NCT06899594
- Testing
- Psilocybin 25 mg
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Kevin Murnane
Cannabis Use, Cannabis Dependence
Neuroimaging of Adolescent Cannabis Use Treatment
This study is testing whether brain activity related to learning can help predict how well teens respond to a treatment program designed to reduce cannabis use.
- Conditions
- Cannabis Use, Cannabis Dependence, Cannabis Use Disorder, Cannabis Abuse
- Trial name
- ACT (NCT07340554)
- Testing
- Contingency Management, Elastic Net Regression
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Indiana University
HIV Infection, Pain
Targeting Effective Analgesia in Clinics for HIV - Patient Cohort
The TEACH patient cohort will characterize a clinic sample of HIV-infected patients on chronic opioid therapy (COT) by describing basic demographics and health status, including characteristics of pain (severity and…
- Conditions
- HIV Infection, Pain, Drug Dependence
- Trial name
- TEACH (NCT02525731)
- Where
- 2 sites in United States
- Volunteers
- 170 people
- Sponsor
- Boston Medical Center
Addiction
Reducing the Abuse Liability of Prescription Opioids
Opioid (commonly called narcotic) pain medicines are, after marijuana, the most commonly abused substances in the United States.
- Trial name
- NCT04587115
- Testing
- Risperidone, Ziprasidone, Oxycodone
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center at San Antonio
Alcohol Drinking, Cannabis Use
Cannabis' Impact on Alcohol Consumption
This study employs a repeated measures experimental design to examine the effect of THC-dominant dose of cannabis and CBD-dominant dose of cannabis, relative to placebo, on subsequent drinking in an alcohol choice task in which…
- Conditions
- Alcohol Drinking, Cannabis Use, Cannabis, Alcohol Use Disorder
- Trial name
- NCT05389930
- Testing
- THC-dominant cannabis, CBD-dominant cannabis, Alcohol
- Where
- United States
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- Brown University
Alcoholism
Sleep Disturbance and Relapse in Individuals With Alcohol Dependence: An Exploratory Mixed Methods Study
Despite research establishing the relationship between sleep disturbances and alcohol use, there is no clear understanding or model for what occurs once individuals who seek inpatient alcoholism treatment are discharged from…
- Trial name
- NCT02181569
- Where
- United States
- Volunteers
- 198 people
- Sponsor
- National Institutes of Health Clinical Center (CC)
Social Exclusion, Chronic Disease
Protocol for a Low Threshold Exercise Intervention for Women Experiencing Homelessness and Addiction.
Background: Frailty is a complex multi-dimensional state of increased vulnerability to adverse health outcomes and is usually associated with older age but there is growing evidence of accelerated ageing and frailty in…
- Conditions
- Social Exclusion, Chronic Disease, Physical Disability, Addiction
- Trial name
- LEAP-W (NCT06264895)
- Testing
- Exercise
- Where
- Ireland
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Dublin, Trinity College
Addiction, Psychiatric Disorder
Validating Promoted Spiritual Experience
This pilot study of 16 patients will demonstrate a specific psychologically focused intervention to affect a spiritual aspect of psychological health and will measure (1) its effects on general distress, depression, anxiety and…
- Trial name
- NCT05485181
- Testing
- Spiritual Intervention
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey
Cocaine Addiction, Cocaine Dependence
Brain Imaging Study of the Effects of Modafinil in Cocaine Addiction
-Context: Study objectives Primary: impact of modafinil versus placebo on DAT density modifications in the striatal and extra-striatal regions in cocaine dependent subjects hospitalised from D3 to D21.
- Trial name
- CAIMAN (NCT00701532)
- Testing
- Modafinil and PET (brain imaging)
- Where
- 2 sites in France
- Volunteers
- 29 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris