Clinical trials: Compulsion
Tobacco Smoking, Harm Reduction
Smoking Harm Reduction Using E-cigarettes and Cytisine
Smoking remains the leading cause of preventable death globally, with high prevalence in disadvantaged populations despite access to free nicotine replacement therapy (NRT) and counseling through Ontario's STOP Program.
- Conditions
- Tobacco Smoking, Harm Reduction, Nicotine
- Trial name
- SHRECC (NCT07274475)
- Testing
- E-cigarette e-liquid, Cytisine
- Volunteers
- 6,000 people
- Sponsor
- Centre for Addiction and Mental Health
Repetitive Compulsive Behavior
tDCS and Urge in BFRBs
The goal of this study is to find out if brain stimulation can help people stop skin-picking or nail-biting. The study wants to answer two main questions: 1.
- Trial name
- NCT07019571
- Testing
- Wireless Multichannel Transcranial Current Stimulator (tDCS), Cue exposure, Boredom induction
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- Gopalkumar Rakesh
PTSD, Addiction
The Course and Outcome of Integreated Trauma and Addiction Treatment Between PTSD and CPTSD
In the ICD-11 post-traumatic stress disorder (PTSD) and complex PTSD (CPTSD) are distinguished. CPTSD is associated with early childhood traumatization and more severe symptom patterns.
- Trial name
- NCT06588309
- Testing
- Eye movement desensitization and reprocessing (EMDR), CRA
- Where
- Netherlands
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- IrisZorg
Vaping, Addiction
The Use of tDCS for Vaping Reduction
Project Summary - tDCS for Vaping Reduction Background: While the prevalence of tobacco smoking has plateaued over the last several years, the prevalence of nicotine vaping (e-cigarettes) continues to increase exponentially in…
- Conditions
- Vaping, Addiction, Transcranial Direct Current Stimulation(tDCS)
- Trial name
- NCT06885606
- Testing
- Active tDCS
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- Centre for Addiction and Mental Health
Cigarette Smoking, Addiction
Electronic Cigarettes as a Harm Reduction Strategy in Individuals With Substance Use Disorder
Patients in addiction treatment have exceptionally higher rate of cigarette smoking and very low quit rates compared to the general population.
- Conditions
- Cigarette Smoking, Addiction, E Cig Use
- Trial name
- NCT04063267
- Testing
- E cigarettes, Nicotine Replacement Therapy
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Mental Health, Substance-Related Disorders
First Face Training Evaluation in Tribal Communities
The goal of this study is to evaluate a culturally grounded training curriculum, First Face for Mental Health, in Tribal communities, using a waitlist controlled trial design.
- Trial name
- NCT05998005
- Testing
- First Face Training Program
- Where
- 9 sites in United States
- Volunteers
- 554 people, healthy volunteers welcome
- Sponsor
- Cambridge Health Alliance
Sexual Addiction, Hypersexualism
tDCS in Treatment of Craving in Sexual Addiction
In patients with addiction to a substance, an increase in activity in the prefrontal cortex induced by transcranial Direct Current Stimulation -tDCS (non-invasive technique, modulating cortical activity by applying low-intensity…
- Trial name
- CAS (NCT04923451)
- Testing
- Active Trans-cranial direct current stimulation (tDCS)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier St Anne
Autistic Disorder
Citalopram for Children With Autism and Repetitive Behavior (STAART Study 1)
This study will determine the efficacy and safety of citalopram compared to placebo in the treatment of children with autism.
- Trial name
- NCT00086645
- Testing
- citalopram hydrobromide
- Where
- 6 sites in United States
- Volunteers
- 149 people
- Sponsor
- Boston University
Addiction, Opioid-use Disorder
Comprehensive CBT (Cognitive Behavioral Therapy) Via reSET App
This research is being done to find out whether an app based cognitive behavior therapy called reSET improves the adherence to and outcome of buprenorphine treatment for opioid use disorder (OUD) in the setting of a Hub and Spoke…
- Trial name
- NCT03826966
- Testing
- reSET
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Milton S. Hershey Medical Center
Addiction Psychological, Healthy
The Turkish Version of the Smartphone Impact Scale
Smartphone Impact Scale (SIS) was originally developed in English to determine the cognitive, affective, social, and behavioral impacts of smartphones in everyday life.
- Conditions
- Addiction Psychological, Healthy, Addiction
- Trial name
- NCT04337775
- Where
- Turkey (Türkiye)
- Volunteers
- 264 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Social Media Addiction, Anxiety
Change in Social Media Use and Well-being Among College Students Receiving a Two-week Exercise or Mindfulness Intervention
The investigators will be randomizing 300 college student participants with high levels of social media use into either a 1) control condition (no intervention), a 2) mindfulness meditation cognitive intervention, or 3) a social…
- Conditions
- Social Media Addiction, Anxiety, Depression Disorder, Wellbeing
- Trial name
- SMUS (NCT07097545)
- Testing
- Mindfulness, Social Media Reduction, Exercise
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Video Game Addiction
The Effect of Telerehabilitation-Based Structured Exercise Program in Video Game-Addicted Adults
The increasing use of computers and mobile devices due to advancing technology has brought with it some negative consequences such as video game addiction.
- Trial name
- NCT06079489
- Testing
- Brochure-Based Exercise Program, Telerehabilitation-Based Structured Exercise Program
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people
- Sponsor
- Biruni University
Nicotine Withdrawal, Tobacco Abstinence
Effects of Transcranial Direct Current Stimulation on Tobacco Withdrawal Symptoms
We hypothesize that transcranial direct current stimulation will reduce tobacco withdrawal symptoms of tobacco dependent smokers abstinent from smoking for more than 10 hours.
- Trial name
- tDCSsmokers (NCT01567982)
- Testing
- tDCS, prefrontal cortex and parietal cortex
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Yale University
Opioid-Related Disorders, Behavior, Addictive
Adolescent Community Reinforcement Approach in Combination With Buprenorphine/Naloxone for Severe Opioid Use
The study assesses whether adding a behavioral intervention, known as the Adolescent Community Reinforcement Approach (A-CRA), to the treatment of individuals already receiving buprenorphine/naloxone can improve treatment success…
- Trial name
- A-CRA/MAT (NCT03287180)
- Testing
- Adolescent Community Reinforcement Approach (A-CRA), Combination of buprenorphine/naloxone 4/1
- Sponsor
- Emory University
Smartphone Addiction
French Language Validation of Questionnaires for the Evaluation of Problematic Screen Use.
The main objective of this research is to linguistically validate the Smartphone Addiction Scale, Nomophobia Questionnaire, The Problematic Use of Mobile Phones scale, Smartphone Addiction Proneness Scale, Digital Addiction Scale…
- Trial name
- VALSCREEN (NCT05585723)
- Testing
- Questionnaires completion
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University Hospital, Grenoble
Addiction
Virtual Reality Relaxation for Addiction Inpatients
This trial examines the immediate session effect of Virtual Reality (VR) relaxation, when used at an addiction inpatient ward for adolescents.
- Trial name
- NCT04293978
- Testing
- CalmPlace
- Where
- Sweden
- Volunteers
- 40 people
- Sponsor
- Karolinska Institutet
Tobacco Use Disorder, Addiction Nicotine
Accelerated dTMS Smoking Cessation
The goal of this clinical trial is to examine whether a 5-day course of bilateral accelerated deep transcranial magnetic stimulation (aTMS) is a feasible treatment to help adults (18-65) with Tobacco Use Disorder to quit smoking.
- Trial name
- NCT07292883
- Testing
- Bilateral deep accelerated repetitive transcranial magnetic stimulation
- Where
- 2 sites in Canada
- Volunteers
- 40 people
- Sponsor
- Waypoint Centre for Mental Health Care
Substance Dependence
Effects of the D3 Antagonist GSK598809 on Food Reward and Reinforcement
This novel compound is a new experimental treatment that may help people to stop compulsive overeating. Compulsive overeating or binge eating is one of the main reasons why people are overweight or obese.
- Trial name
- NCT01039454
- Testing
- GSK598809 Capsules
- Where
- 2 sites in United Kingdom
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Smartphone Addiction
Smartphone Addiction and Temporomandibular Dysfunction
The aim of this study was to investigate the effect of smartphone addiction on temporomandibular dysfunction with the determinants of pain threshold, head posture and neck disability level.
- Trial name
- NCT06818318
- Testing
- Temporomandibular disorder, Smartphone Addiction Scale-Short Form, Neck Disability Index
- Where
- Turkey (Türkiye)
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Bandırma Onyedi Eylül University
Orthopaedic Fractures, Socioeconomic Factors
Trial of Social Work Services in Fracture Clinic Setting
Every year, many Canadians sustain a fracture that requires surgical treatment and results in a long recovery period. During this recovery period, patients may experience new or worsening mental health issues including…
- Trial name
- SWRCT (NCT06973655)
- Testing
- Social Work support
- Where
- 2 sites in United States, Canada
- Volunteers
- 2,000 people
- Sponsor
- Sheila Sprague