Clinical trials: Compulsion
Pathological Gambling
Cognitive Control Training in Online Problem Gambling
An online single blinding, randomized, comparative therapeutic web-based, controlled trial. The main objective of the study is to assess the clinical efficacy of an online computerized cognitive training program targeted on…
- Trial name
- TRAIN-ONLINE (NCT03673800)
- Testing
- Experimental Group, Control Group
- Where
- France
- Volunteers
- 200 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Cocaine Dependence
Cocaine Use Reduction With Buprenorphine
The aim of this study is to investigate the safety and effectiveness of buprenorphine in the presence of naltrexone for the treatment of cocaine dependence.
- Trial name
- CURB (NCT01402492)
- Testing
- Buprenorphine + Naltrexone
- Where
- 11 sites in United States
- Volunteers
- 302 people
- Sponsor
- University of California, Los Angeles
Food Addiction
Ultra Crave: An Investigation of Ultra-Processed Food
This study experimentally investigates whether a reduction in ultra-processed (UP) food intake (1) causes aversive withdrawal symptoms in humans, (2) increases the motivational salience of UP food cues and, if so, (3) whether…
- Trial name
- NCT06044285
- Testing
- Low UP (meals provided), Low UP (self-guided), Active Control
- Where
- United States
- Volunteers
- 210 people
- Sponsor
- University of Michigan
Substance Use Disorders, Posttraumatic Stress Disorder
Written Exposure Therapy for Veterans With SUD and PTSD
The proposed project will evaluate the efficacy of written exposure therapy (WET) among Veterans engaged in substance use disorder (SUD) treatment, who present with co-occurring posttraumatic stress disorder (PTSD).
- Trial name
- WET (NCT05327504)
- Testing
- Written Exposure Therapy, Neutral Topic Writing
- Where
- United States
- Volunteers
- 170 people
- Sponsor
- VA Office of Research and Development
Smoking Cessation, Smoking, Tobacco
Helping Poor Smokers Quit
Using a 2x2 randomized factorial design, we will conduct a statewide field trial in Missouri to compare the relative and combined effects of these two strategies for augmenting an existing, evidence-based tobacco quitline…
- Conditions
- Smoking Cessation, Smoking, Tobacco, Smoking, Cigarette, Smoking, Pipe
- Trial name
- NCT03194958
- Testing
- Specialized Quitline, Basic Needs Navigator
- Where
- United States
- Volunteers
- 1,944 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Addiction
Effects of rTMS and tDCS Treatment on Brain Function, Craving and Relapse Prevention
Addiction is known as a chronic relapsing brain disorder that has a high cost to patients, family and society. Its ranking in cause of death is 8th globally, and substance abuse contributes 5.4% of the total global burden of…
- Trial name
- NCT03549065
- Testing
- Brain Stimulation
- Sponsor
- Medical University of South Carolina
Internet Addiction Level, Perceived Stres Level
Horticultural Practices for Children
The study was conducted with a parallel group randomized controlled experimental design to determine the effect of horticultural practices on internet addiction, social skills and stress levels in children.
- Conditions
- Internet Addiction Level, Perceived Stres Level, Social Skill Level
- Trial name
- NCT06489405
- Testing
- Horticultural practices
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Gazi University
Cannabis Dependence
Neural Indices Associated With Relapse in Cannabis Dependence
The aim of this fMRI study is to investigate neural indices of relapse in cannabis dependence. The development and maintenance of drug addictions have been associated with deficits in cognitive control, craving and impaired…
- Trial name
- NCT02801422
- Testing
- fMRI
- Where
- Germany
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- University of Electronic Science and Technology of China
Alcohol Use Disorder (AUD)
Renewed Recovery: a Pilot Test of a Web-Based Mindfulness-Based Relapse Prevention Continuing Care Intervention for Alcohol Use Disorder
This study aims to design, implement, and evaluate a pilot test of a web-based Mindfulness-Based Relapse Prevention (MBRP) continuing care intervention to support individuals with alcohol use disorder (AUD) exiting standard…
- Trial name
- NCT06987526
- Testing
- Mindfulness-Based Relapse Prevention
- Where
- 2 sites in United States
- Volunteers
- 30 people
- Sponsor
- University of Georgia
Obsessive-Compulsive Disorder
Study to Determine the Efficacy and Safety of Adjunctive Topiramate in the Treatment of Obsessive-Compulsive Disorder
The purpose of this study is to determine if a drug called topiramate is safe and effective as an add-on therapy in the treatment of Obsessive-Compulsive Disorder (OCD).
- Trial name
- NCT00187928
- Testing
- Topiramate
- Where
- United States
- Volunteers
- 96 people
- Sponsor
- University of Florida
Autism Spectrum Disorder
Pimavanserin for Rigid-compulsive Symptoms in Autism Spectrum Disorder
This Phase 2 study examines the safety, tolerability, and preliminary efficacy of pimavanserin in individuals with Autism Spectrum Disorder.
- Trial name
- NCT05999240
- Testing
- Pimavanserin Tartrate 34 Mg ORAL CAPSULE [NUPLAZID]
- Where
- 2 sites in United States
- Volunteers
- 30 people
- Sponsor
- New York State Psychiatric Institute
Dental Pain and Sensation Disorder, Anesthesia, Local
Impact of Tramadol Addiction On Dental Anesthesia Success
The aim is to investigate and to find a correlation between tramadol addiction misuse among Algerian males and Dental Local Anesthesia success while performing dental care and oral surgeries.
- Conditions
- Dental Pain and Sensation Disorder, Anesthesia, Local, Addiction, Opioid
- Trial name
- NCT05908305
- Testing
- articaine@ (4% 1:100000 epinephrine) dental anesthesia
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University of Algiers
Opioid Dependence, Opioid Use Disorder
Increasing Patient Knowledge of the Signs of Opioid Overdose and Naloxone in a Suburban Treatment Program
The purpose of this study is to determine the effect that an educational intervention has on patient knowledge of the signs of opioid overdose and appropriate use of naloxone in a suburban outpatient treatment program.
- Trial name
- NCT02120612
- Testing
- Naloxone Education Intervention
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Edward Hospital
Suicidal Ideation, Psychiatric Disorder
A Brief Mindfulness-Based Intervention for Suicidal Ideation
The primary aim of this study is to determine whether a Brief Mindfulness-Based Intervention for Suicidal Ideation (MB-SI) is feasible and safe to implement.
- Conditions
- Suicidal Ideation, Psychiatric Disorder, Addiction
- Trial name
- MB-SI (NCT04099173)
- Testing
- Brief Mindfulness Based Intervention
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- VA Salt Lake City Health Care System
Substance Abuse
Computer-assisted Delivery of Cognitive Behavioral Therapy for Mental Health and Addictions in Canada
Computer-based Training for Cognitive Behavioural Therapy (CBT4CBT) is a new on-line addiction treatment developed by Dr Kathleen Carroll at the Yale School of Medicine in New Haven, Connecticut.
- Trial name
- NCT03230669
- Testing
- cbt4cbt
- Where
- Canada
- Volunteers
- 148 people, healthy volunteers welcome
- Sponsor
- University of Prince Edward Island
Food Addiction, Obesity
Validation of a Food Addiction Screening Test
Food addiction (FA) is a behavioral addiction characterized by a high consumption of palatable foods, which markedly activate the reward system, despite adverse consequences.
- Trial name
- FAST - FR (NCT04126239)
- Testing
- Online survey - questionnaire
- Where
- France
- Volunteers
- 1,610 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Technology Literacy, Reading Habits
Factors Linked to AI Literacy in University Students
This study investigates the relationships between artificial intelligence (AI) literacy and factors such as academic achievement, reading habits, smartphone addiction, and internet addiction among university students.
- Conditions
- Technology Literacy, Reading Habits, Smartphone Addiction, Internet Addiction
- Trial name
- NCT06689319
- Testing
- Assessment of Artificial Intelligence Literacy
- Where
- Turkey (Türkiye)
- Volunteers
- 184 people
- Sponsor
- Nagihan Acet
Craving, Depression, Anxiety
Repetitive Transcranial Magnetic Stimulation in Amphetamine Addiction
The study aims to test whether transcranial magnetic stimulation (TMS) improves the craving, depression, anxiety and cognitive function during the abstinent period of methamphetamine users.
- Conditions
- Craving, Depression, Anxiety, Amphetamine Addiction
- Trial name
- NCT04993300
- Testing
- transcranial magnetic stimulation (TMS)
- Where
- Taiwan
- Volunteers
- 5 people
- Sponsor
- National Taiwan University Hospital
Methamphetamine Addiction
A Pilot Trial of Dextroamphetamine for Methamphetamine Dependence
The purpose of this study is to assess the safety and effectiveness dextroamphetamine to help methamphetamine users quit or cut down on their use. The study lasts for 9 weeks.
- Trial name
- 1D (NCT00630682)
- Testing
- Dextroamphetamine
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- California Pacific Medical Center Research Institute
Risk Behavior, Social Media Addiction
Effect of Solution-Focused Approach on the Internet,Social Media Addiction and Self-Efficacy Levels OfNursing Students
The purpose of this research; is to determine the effect of solution-oriented approach on internet, social media addiction and self-efficacy levels of nursing students.
- Conditions
- Risk Behavior, Social Media Addiction, Internet Addiction
- Trial name
- NCT06674746
- Testing
- SOLUTION FOCUSED APPROACH
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cumhuriyet University