Clinical trials: Compulsion
Hepatitis C, Medication Adherence
Intensive Models of HCV Care for Injection Drug Users
Injection drug users (IDUs) constitute 60% of the approximately 5 million people in the U.S. infected with hepatitis C virus (HCV). HCV treatment leading to sustained viral response (SVR) is associated with increased survival.
- Trial name
- NCT01857245
- Testing
- Intensive Models (mDOT and CGT) of HCV Care
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Prisma Health-Upstate
Cocaine Dependence
Therapeutic Cocaine Vaccine: Human Laboratory Study
Clinical data demonstrate that a cocaine vaccine (TA-CD: Celtic Pharmaceutical) produces selective anti-cocaine antibodies, yet the impact of these antibodies on cocaine's direct effects is unknown.
- Trial name
- NCT00965263
- Testing
- Cocaine vaccine (TA-CD)
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- New York State Psychiatric Institute
Obsessive Compulsive Disorder
Duloxetine for the Treatment of Obsessive Compulsive Disorder (OCD)
The purpose of this study is to assess the efficacy of Duloxetine in the treatment of obsessive compulsive disorder.
- Trial name
- FIJ-MC-1003 (NCT00464698)
- Testing
- Duloxetine
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Massachusetts General Hospital
Methamphetamine Dependence
Modafinil vs Placebo for the Treatment of Methamphetamine Dependence
Modafinil is a non-amphetamine type stimulant that acts as a wakefulness-promoting drug, and is approved for managing symptoms of narcolepsy (i.e., daytime somnolence).
- Trial name
- Modafinil (NCT00469508)
- Testing
- Modafinil
- Where
- United States
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Cocaine Dependence, Alcohol Dependence
VIVITROL as a Treatment for Cocaine and Alcohol Dependence
To evaluate the efficacy of VIVITROL (naltrexone for extended-release injectable suspension) for the treatment of co-occurring cocaine and alcohol dependence
- Trial name
- NCT00777062
- Testing
- VIVITROL (Naltrexone extended-release injectable suspension)
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- University of Pennsylvania
Substance-Related Disorders, Opioid-Related Disorders
Incentives to Decrease Opioid Use - Pilot
The purpose of this study is to address two key questions in the literature on incentives for substance use. The first question is whether it is more effective to directly incentivize the outcome of interest - drug abstinence …
- Conditions
- Substance-Related Disorders, Opioid-Related Disorders, Behavior Therapy
- Trial name
- NCT04235582
- Testing
- App + Inputs Contingency Management, App + Outcomes Contingency Management
- Where
- 3 sites in United States
- Volunteers
- 36 people
- Sponsor
- Wake Forest University Health Sciences
Methamphetamine Dependence
Clinical Efficacy of Atomoxetine for Methamphetamine Dependence
The purpose of this study is to examine the ability of atomoxetine compared to placebo to increase time to relapse in methamphetamine dependent volunteers.
- Trial name
- ATM (NCT01557569)
- Testing
- Atomoxetine
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Arkansas