Clinical trials: Compulsive Behavior
Substance-related Disorders
Women's Treatment and Early Recovery
Approximately 25 million Americans struggle with alcohol or drug problems annually. Abuse of alcohol and drugs is costly to our nation, exacting more than $428 billion in costs related to crime, lost work productivity and health…
- Trial name
- MBRP-W (NCT02977988)
- Testing
- Mindfulness Meditation, Brain and Recovery (B&R)
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- University of Southern California
Internet Gaming Disorder
Effect of Computer-Based Game and HIIT Towards Symptoms, Executive Function and Neuroplasticity in Teens with IGD
The goal of this clinical trial is to learn how effective a combined therapy of computer-based game and also high-intensity interval training (HIIT) physical exercise to improve the clinical symptoms, executive function and…
- Trial name
- NCT06582979
- Testing
- Computer-Based Game Therapy, High-Intensity Interval Training
- Where
- Indonesia
- Volunteers
- 44 people
- Sponsor
- Universitas Indonesia
Trichotillomania, Excoriation (Skin-Picking) Disorder
Internet CBT for Trichotillomania and Skin Picking Disorder
The primary aim of the study is to test the feasibility, safety and efficacy of a manual based, Internet-delivered, behavior therapy (I-BT) for trichotillomania and skin picking disorder.
- Trial name
- NCT04559750
- Testing
- Internet delivered behavior therapy (I-BT)
- Where
- Sweden
- Volunteers
- 25 people
- Sponsor
- Karolinska Institutet
Cannabis Use
Impulsivity and Time Perception
Cannabis smokers having begun prematurely their consumption (before 16 years) present a persistent impulsivity much later after have stopped their consumptions.
- Trial name
- NCT03162640
- Where
- France
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- University Hospital, Strasbourg, France
Obsessive-Compulsive Disorder
ERP Plus Improv Group Therapy for OCD (IMPROVE Study)
The goal of this study is to pilot test a novel group therapy intervention for adults with OCD.
- Trial name
- NCT06265233
- Testing
- Group Improv sessions, Group Exposure and Response Prevention (ERP) Therapy
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Stanford University
Obsessive Compulsive Disorder
Modification of Cerebral Activity of Obsessive Compulsive Disorder (OCD) Patients During Cognitive and Behavioral Therapy
Obsessive compulsive Disorder (OCD) is a frequent psychiatric disorder. Obsessions and compulsions are the two manifestations of this disease.
- Trial name
- TOC TOC (NCT01331876)
- Testing
- Cognitive and behavioral Therapy
- Where
- France
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Alcohol Use Disorder, Obesity and Overweight
Tirzepatide for Alcohol Use Disorder
The objective of this Phase 2 randomized controlled trial is to evaluate the effects of weekly tirzepatide (vs. placebo) on alcohol consumption and cardiometabolic outcomes in adults with alcohol use disorder and overweight or…
- Conditions
- Alcohol Use Disorder, Obesity and Overweight, Alcohol
- Trial name
- NCT06994338
- Testing
- Tirzepatide
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- University of Southern California
Addiction, Behavioral Addiction
Mobile Health for Problematic Behaviors and Substance Use
The aim of the study is to evaluate the effectiveness of long-term and short-term app-based self-guided psychological interventions to reduce craving and lapse risk in problematic behaviors (compulsive sex, pornography…
- Conditions
- Addiction, Behavioral Addiction, Nicotine Addiction, Nicotine Dependence
- Trial name
- NCT05434429
- Testing
- mobile application
- Where
- Poland
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- PredictWatch
Trichotillomania (Hair-Pulling Disorder), Trichotillomania
Semaglutide (Wegovy) Treatment for Trichotillomania
This research study is testing the effectiveness and safety of semaglutide (Wegovy) in people with trichotillomania, also known as hair-pulling disorder.
- Conditions
- Trichotillomania (Hair-Pulling Disorder), Trichotillomania, Hair Pulling Disorder, Hair Pulling
- Trial name
- NCT07282769
- Testing
- Semaglutide
- Volunteers
- 10 people
- Sponsor
- University of Chicago
Drug Addiction
The Health of Women Monitored in the Addiction Department of the Strasbourg University Hospitals
The health of women suffering from addiction is little known and little explored in the literature. Indeed, they represent only 20% of addicted patients in general and are encountered primarily during pregnancy or complex…
- Trial name
- Santé-Fem (NCT07033728)
- Where
- France
- Volunteers
- 55 people
- Sponsor
- University Hospital, Strasbourg, France
Smartphone Addiction, Postural Disorders
Smartphone Addiction, Posture and Breathing Control in University Students
The aim of this study is to investigate the effects of smartphone addiction on postural problems and breathing control in healthy university students.
- Conditions
- Smartphone Addiction, Postural Disorders, Dysfunctional Breathing
- Trial name
- NCT07615322
- Testing
- Observational Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Istanbul Medeniyet University
Tiletamine Use Disorder, Substance Use Disorder (SUD)
The Efficacy of Transcutaneous Auricular Vagus Nerve Stimulation in Individuals With Tiletamine Use Disorder
Participants diagnosed with tiletamine use disorder will be assigned to active or sham taVNS for 5 days. Clinical outcomes ( e.g., behavioral paradigms measures and clinical scales ) and physiological markers (e.g., EEG and ECG)…
- Conditions
- Tiletamine Use Disorder, Substance Use Disorder (SUD), Drug Craving
- Trial name
- taVNS-Tiletami (NCT07689981)
- Testing
- Transcutaneous Auricular Vagus Nerve Stimulation
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Shanghai Mental Health Center
Substance Dependence
GSK618334 Repeat Dose Study
The proposed study will evaluate the safety, tolerability, pharmacokinetics (PK) and pharmacodynamics of repeated oral doses of GSK618334 in healthy male and female volunteers.
- Trial name
- NCT01036061
- Testing
- GSK618334 Low Dose, GSK618334 PET subjects, GSK618334 Medium Dose
- Where
- United Kingdom
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
HIV Infection, Pain
Targeting Effective Analgesia in Clinics for HIV - Patient Cohort
The TEACH patient cohort will characterize a clinic sample of HIV-infected patients on chronic opioid therapy (COT) by describing basic demographics and health status, including characteristics of pain (severity and…
- Conditions
- HIV Infection, Pain, Drug Dependence
- Trial name
- TEACH (NCT02525731)
- Where
- 2 sites in United States
- Volunteers
- 170 people
- Sponsor
- Boston Medical Center
Alcohol Use Disorder
Lacosamide Effects on Alcohol Self Administration and Craving in Heavy Drinkers
This is a double-blind, randomized, placebo-controlled, crossover design trial tested the effect of lacosamide on alcohol self-administration and craving following a priming dose of alcohol.
- Trial name
- NCT03271528
- Testing
- Lacosamide
- Where
- United States
- Volunteers
- 66 people
- Sponsor
- Boston Medical Center
Health Services Research, Quality of Life
Quality of Life and Addiction Among Hospital Night Workers
The current context of the Covid-19 health crisis leads to an over-solicitation of health systems, with hospital staff in the front line.
- Conditions
- Health Services Research, Quality of Life, Addiction, Substance-Related Disorders
- Trial name
- ALADDIN (NCT04291534)
- Where
- 2 sites in France
- Volunteers
- 1,800 people
- Sponsor
- University Paris 7 - Denis Diderot
Addiction, Opioid
Role of High Frequency RTMS in Management of Opioid Use Disorder
This study aims to evaluate the role of repetitive Transcranial Magnetic Stimulation (rTMS) applied to the left dorsolateral prefrontal cortex (DLPFC) in reducing pain, decreasing craving, alleviating withdrawal symptoms…
- Conditions
- Addiction, Opioid, RTMS
- Trial name
- NCT06689072
- Testing
- rTMS, Psychotherapy
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Assiut University
Food Addiction, Obesity, Morbid
Deep Transcranial Magnetic Stimulation (dTMS) of the Medial Prefrontal Cortex in Food Addiction and Obesity
This experiment is based on a unique technique of deep Transcranial magnetic stimulation (dTMS) of the brain's cortex, aiming to produce weight loss in food-addicted severely obese adults.
- Trial name
- FAOB-mPFC (NCT04692909)
- Testing
- dTMS with mPFC stimulation
- Where
- Israel
- Volunteers
- 24 people
- Sponsor
- Soroka University Medical Center
Smartphone Addiction, Thumb Injury
Smartphone Addiction on the Biomechanical Properties of Thumb Muscles and Thumb Sensory Sensitivity
This study will aim to assess the effects of smartphone addiction on thumb muscle biomechanics and sensory sensitivity among university students.
- Trial name
- NCT07040267
- Testing
- Thumb evaluations
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people
- Sponsor
- Saglik Bilimleri Universitesi
Obsessive Compulsive Disorder
Computer Assisted Cognitive Behavior Therapy for Obsessive Compulsive Disorder: A Comprehensive Stepped-Care Approach
The goal of this project is to improve access to effective treatments for obsessive compulsive disorder (OCD) through the use of web-based cognitive behavioral therapy (CBT) treatment.
- Trial name
- NCT01522287
- Testing
- Computer-Assisted Cognitive Behavior Therapy (BT STEPS)
- Where
- United States
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Center for Psychological Consultation