Clinical trials: Compulsive Disorder
Obsessive-Compulsive Disorder
Treatment of Obsessive-Compulsive Disorder (OCD) in Children
The purpose of this study is to compare 3 treatments for children with OCD: medication (sertraline, SER) alone vs OCD-specific therapy (Cognitive Behavior Therapy, CBT) vs medication plus therapy.
- Trial name
- NCT00000384
- Testing
- Cognitive Behavior Therapy, Educational Support, Sertraline
- Where
- 2 sites in United States
- Sponsor
- University of Pennsylvania
Obsessive-Compulsive Disorder, Pediatric Psychiatric Disorder
Transcranial Direct Current Stimulation (tDCS) in Pediatric Obsessive Compulsive Disorder (OCD)
In this study, the investigators aim to understand the role of transcranial direct current stimulation (tDCS) in modulating aberrant neurocognitive processes implicated in pediatric patients with obsessive compulsive disorder…
- Trial name
- NCT04548609
- Testing
- Transcranial Direct Current Stimulation
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Massachusetts General Hospital
Hoarding Disorder, Virtual Reality Based Therapy
Non-Immersive Virtual Environments for the Treatment of Hoarding Disorder
This experimental trial investigates whether Virtual Reality Exposure (VRe) helps individuals reduce the difficulty of discarding personal possessions. It will also evaluate the psychological state impacts of the intervention.
- Conditions
- Hoarding Disorder, Virtual Reality Based Therapy, General Population (no Specific Condition or Disease)
- Trial name
- HD&VR (NCT07160543)
- Testing
- Imagination Exposure, Non-immersive Virtual Reality Exposure
- Where
- Italy
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Padova
Anxiety Disorders, Panic Disorder
Initial Severity and Antidepressant Efficacy for Anxiety Disorders: an Individual Patient Data Meta-analysis
Anxiety disorders are common disorders, which pose a major burden to society and the individual. An anxiety disorder may be treated with medication, in particular with antidepressants such as the selective serotonin reuptake…
- Conditions
- Anxiety Disorders, Panic Disorder, Obsessive-compulsive Disorder, Post-traumatic Stress Disorder
- Trial name
- NCT02476136
- Testing
- paroxetine, duloxetine, fluoxetine or venlafaxine
- Volunteers
- 8,800 people
- Sponsor
- prof. Peter de Jonge
Obsessive Compulsive Disorder
Tolerability, Safety and Efficacy of the HAC-Coil Deep Transcranial Magnetic Stimulation in Medication Resistance Obsessive Compulsive Disorder (OCD) Subjects
The purpose of this study is to test whether the combination of deep transcranial magnetic stimulation (DTMS) treatment with customary medication for obsessive compulsive disorder (OCD) patients is effective than treatment that…
- Trial name
- NCT01343732
- Testing
- Deep TMS
- Where
- Israel
- Volunteers
- 40 people
- Sponsor
- Brainsway
Internet Gaming Disorder
Mechanism of BCI-Based Dual-Target Neurofeedback Training in Improving Cognitive Control Deficits in Internet Gaming Disorder
Addressing the three core issues in research on cognitive control deficits in Internet Gaming Disorder (IGD)-unclear neural mechanisms, limited intervention targets, and poor patient compliance-this project innovatively…
- Trial name
- NCT07843615
- Testing
- "Activate Neural Circuits + Promote Social Rewards" Dual-target Neurofeedback Training, "Activate Only the Neural Circuits" Neurofeedback Training
- Where
- China
- Volunteers
- 120 people
- Sponsor
- The First Affiliated Hospital of Bengbu Medical University
Obsessive-Compulsive Disorder, Tricholemmoma
Neural Mechanisms of Response Inhibition Training for OCRD
The impaired ability to suppress an inappropriate but pre-potent response (response inhibition; RI) characterizes several debilitating clinical problems, including obsessive-compulsive and related disorders (OCRD) such as…
- Conditions
- Obsessive-Compulsive Disorder, Tricholemmoma, Skin-Picking
- Trial name
- OCRD (NCT05377125)
- Testing
- Computerized cognitive training
- Where
- United States
- Volunteers
- 118 people
- Sponsor
- University of Wisconsin, Milwaukee
Obsessive-compulsive Disorder
Internet-based vs Face-to-face Cognitive Behavioural Therapy for Obsessive-compulsive Disorder
Randomized controlled non-inferiority trial comparing therapist-guided Internet-based Cognitive behavioral therapy (ICBT), self-guided ICBT, and individual face-to-face (f2f) CBT for Obsessive-Compulsive Disorder (OCD) in adults.
- Trial name
- NCT02541968
- Testing
- Cognitive-behavioral therapy (face-to-face), Internet-based Cognitive-behavioral therapy, Internet-based Cognitive-behavioral therapy without therapist support
- Where
- Sweden
- Volunteers
- 120 people
- Sponsor
- Karolinska Institutet
Obsessive-Compulsive Disorder
Transcranial Magnetic Stimulation (TMS) and Obsessive Compulsive Disorder (OCD)
This study will evaluate the clinical efficacy of functional Magnetic Resonance Imaging (fMRI) guided 1 Hz repetitive Transcranial Magnetic Stimulation (rTMS) applied to the Supplementary Motor Area (SMA) in OCD patients who have…
- Trial name
- NCT00106249
- Testing
- Repetitive Transcranial Magnetic Stimulation (rTMS)
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- New York State Psychiatric Institute
Alcohol Use Disorder, Post Traumatic Stress Disorder
Piloting "Signs of Safety": A Deaf-Accessible Therapy Toolkit for Alcohol Use Disorder and Trauma
The U.S. Deaf community - more than 500,000 Americans who communicate using American Sign Language (ASL) - experiences nearly triple the rate of lifetime problem drinking and twice the rate of trauma exposure as compared to the…
- Trial name
- NCT03845985
- Testing
- Seeking Safety + Signs of Safety toolkit
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- University of Massachusetts, Worcester
Obsessive-Compulsive Disorder
Refining the Target for Deep Brain Stimulation (DBS) in Severe, Treatment Refractory Obsessive Compulsive Disorder (OCD)
In select, therapy resistent patients with Obsessive Compulsive Disorder (OCD) Deep Brain Stimulation (DBS) has been used as a treatment.
- Trial name
- NCT01985815
- Testing
- VC/VS stimulation
- Where
- Belgium
- Volunteers
- 6 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Internet Addiction
WeChat-based Intervention for Internet Addiction
The study aims to design an integrated model which combined self-initiated online learning and personalized interactive behavioral support delivered via WeChat for university students to reduce internet addiction level.
- Trial name
- NCT05906108
- Testing
- Self-initiated learning, Personalized and interactive behavioural support, General health information
- Where
- Hong Kong
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Prof. Wang Man-Ping
Social Media Addiction
4-STEP Training Program for Social Media Addiction, Cognitive Fatigue, Psychological Distress, Academic Burnout and Procrastination Among Students
This study aims to evaluate the effectiveness of a structured four-step training program for reducing social media addiction and its associated psychological and academic difficulties among school and university students.
- Trial name
- 4-STEP-TPS (NCT07821489)
- Testing
- 4-STEP-TPS
- Where
- Pakistan
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Government College University Faisalabad
Alcohol Use Disorder, Couples
Building and Pilot Testing a Couples-based Smartphone Systems to Address Alcohol Use Disorder
This project will develop and pilot test a new smartphone-based system for AUD patients, their partners, and clinicians called PartnerCHESS. PartnerCHESS will integrate key features of ABCT and A-CHESS.
- Conditions
- Alcohol Use Disorder, Couples, Behavior, Addictive
- Trial name
- NCT04059549
- Testing
- PartnerCHESS, A-CHESS
- Where
- United States
- Volunteers
- 68 people
- Sponsor
- University of Wisconsin, Madison
Problematic Smartphone Use, Perceived Stress
The Effect of Mindfulness-Based Stress Reduction Programme on Smartphone Addiction, Stress and Quality of Life in University Students
This study examined whether a brief mindfulness-based stress reduction program could help university students reduce problematic smartphone use and perceived stress and improve their quality of life.
- Conditions
- Problematic Smartphone Use, Perceived Stress, Health-Related Quality of Life
- Trial name
- Mindfulness (NCT06819540)
- Testing
- Brief Mindfulness-Based Stress Reduction (MBSR) Program
- Where
- Turkey (Türkiye)
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- Hasan Kalyoncu University
Addiction
Prognosis of Behavioral Addiction in Parkinson's Disease
Our hypothesis is that the conventional treatment of Behavioral Addiction in Parkinson's disease is often not effective, and that affects the motor aspects (worsening akinéto-rigid syndrome and / or worsening of dyskinesia due to…
- Trial name
- PROBA-PD (NCT02671240)
- Where
- France
- Volunteers
- 164 people
- Sponsor
- University Hospital, Strasbourg, France
Pediatric Acute-onset Neuropsychiatric Syndrome (PANS)
Pediatric Acute-Onset Neuropsychiatric Syndrome (PANS)
Background: PANS is an illness that comes on suddenly in children. The full name is Pediatric Acute-Onset Neuropsychiatric Syndrome. It can cause sudden obsessive-compulsive behaviors.
- Trial name
- NCT03507218
- Where
- 8 sites in United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Alcoholic Liver Disease
French National MICMAF Cohort
Excessive alcohol consumption is a major public health problem, particularly in France. It is the leading cause of cirrhosis and hepatocellular carcinoma.
- Trial name
- MICMAF (NCT05895890)
- Testing
- Sequential sampling (stool, saliva, serum) .
- Where
- France
- Volunteers
- 1,000 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Obsessive Compulsive Disorder
Attention Training for Childhood Obsessive Compulsive Disorder: An Open Case Series
Pediatric Obsessive Compulsive Disorder (OCD) is a chronic, impairing condition that accrues significant concurrent and long-term risk to affected youth.
- Trial name
- AMPOCD (NCT01708226)
- Testing
- Attention Modification Program
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- University of California, Los Angeles
Obsessive-compulsive Disorder, Depression
Rechargeable Neurostimulators in Deep Brain Stimulation for Psychiatric Disorders
From 1999 onwards, Deep Brain Stimulation [DBS] has been proposed as an alternative to capsulotomy in refractory cases of Obsessive-Compulsive Disorder [OCD].
- Trial name
- NCT02685280
- Testing
- Medtronic Restore Advanced 37713
- Volunteers
- 12 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven