Clinical trials: Computed Tomography Angiography
Coronary Artery Disease
A Coronary Computed Tomography Angiography-guided Intervention for High Risk Cardiovascular Disease Population in Rural China
The CARDIAC trial is a prospective, parallel, open-label cluster randomized trial that aims to determine the effectiveness of a coronary computed tomography angiography (CTA)-guided intensive intervention strategy, as compared…
- Trial name
- CARDIAC (NCT07416344)
- Testing
- CTA-guided Intensive Intervention Strategy, Comprehensive Intervention Strategy
- Where
- 16 sites in China
- Volunteers
- 14,980 people
- Sponsor
- Harbin Medical University
Pulmonary Embolism, Interstitial Lung Disease
Predictors of Pulmonary Embolism in Interstitial Lung Disease With Worsening Symptoms
People with interstitial lung disease (ILD) can sometimes experience a sudden and severe worsening of their breathing. While this can be caused by a flare-up of the lung disease itself, it can also be caused by a blood clot in…
- Conditions
- Pulmonary Embolism, Interstitial Lung Disease, Idiopathic Pulmonary Fibrosis, Connective Tissue Disease-associated Interstitial Lung Disease
- Trial name
- NCT07728448
- Volunteers
- 70 people
- Sponsor
- Assiut University
Coronary Artery Disease (CAD), Stable Angina Pectoris
Identification of Lesion Characteristics in Coronary Plaques Using Multimodality Intravascular Imaging and Novel Photon-counting CT in Stable Angina
Coronary artery disease, caused by the furring up of the heart arteries by atherosclerosis, is a major cause of death in the UK.
- Conditions
- Coronary Artery Disease (CAD), Stable Angina Pectoris, Ischaemic Heart Disease (IHD)
- Trial name
- ILUMINA (NCT07864025)
- Testing
- observational study
- Where
- United Kingdom
- Volunteers
- 70 people
- Sponsor
- Queen Mary University of London
Angina Pectoris, Coronary Heart Disease
Scottish COmputed Tomography of the HEART Trial
The primary objective of the study is to see if coronary artery calcium score and computed tomography coronary angiogram alters the proportion of patients diagnosed with angina due to coronary heart disease.
- Trial name
- SCOT-HEART (NCT01149590)
- Testing
- Computer Tomography Angiography
- Where
- 12 sites in United Kingdom
- Volunteers
- 4,138 people
- Sponsor
- University of Edinburgh
Cardiovascular Risk Factor
Peri-vascular Adipose Tissue Inflammation Evaluated Using Coronary CT Angiography
The P-VECT Study proposes to test the use of CCTA-derived FAI measurements in a group of patients with coronary artery inflammation, who will receive routinely-used statin and aspirin treatment.
- Trial name
- P-VECT (NCT04181749)
- Testing
- aspirin and atorvastatin
- Where
- 3 sites in United Kingdom
- Volunteers
- 200 people
- Sponsor
- University of Leicester
Aortic Valve Stenosis, Coronary Artery Disease
Evaluation of Fractional Flow Reserve Calculated by Computed Tomography Coronary Angiography in Patients Undergoing TAVR
The objective of this study is to evaluate the relationship between fractional flow reserve (FFR) derived from coronary computed tomography angiography (FFRct) before transcatheter aortic valve replacement (TAVR) and FFR after…
- Trial name
- FORTUNA (NCT03665389)
- Testing
- iFR / FFR measurement
- Volunteers
- 25 people
- Sponsor
- Kobe University
Coronary Angiography, Coronary Disease
Usefulness of Coronary CT Angiography in Patients With Inconclusive Stress Test Results
The purpose of this study is to evaluate the usefulness of performing a "cat scan" of the heart arteries in patients (without a known history of heart disease) seen by their physician for chest pain.
- Trial name
- IMPACCT (NCT00465335)
- Volunteers
- 200 people
- Sponsor
- Corewell Health East
Stable Ischemic Heart Disease, Coronary Artery Disease
Evaluation of Diagnostic Accuracy, Safety, and Cost-Effectiveness of the Non-Invasive Cardiolens FFR-CT Pro Method to Measure the Fractional Flow Reserve in Diagnostics of Chronic Coronary Syndromes Versus the Standard Diagnostic Modalities.
A multicentre, post-marketing, observational trial in 450 patients, whose standard diagnostic workup for chronic coronary syndromes provided for Invasive Coronary Angiography (ICA).
- Trial name
- NCT04777513
- Testing
- CCTA (Coronary Computed Tomography Angiography), ICA (Invasive Coronary Angiography), FFR (Fractional Flow Reserve)
- Where
- 11 sites in Poland
- Volunteers
- 450 people
- Sponsor
- Hemolens Diagnostics Sp. z o.o.
Coronary Artery Disease, Atherosclerosis
Coronary Artery Geometry and the Severity of Coronary Atherosclerosis
The purpose of this study is to investigate the potential association of coronary artery geometry, based on coronary CT angiography (CCTA), with the complexity and the severity of coronary atherosclerosis.
- Conditions
- Coronary Artery Disease, Atherosclerosis, Atherosclerotic Plaque, Stable Angina
- Trial name
- GEOMETRY-CTA (NCT04185493)
- Testing
- CCTA
- Where
- Greece
- Volunteers
- 100 people
- Sponsor
- Aristotle University Of Thessaloniki
Atherosclerosis
Incident COronary EveNts Identified by Computed Tomography
The Incident COronary EveNts Identified by Coronary Tomography (ICONIC) trial is a nested, case-control study derived from the dynamic CONFIRM registry, and is based on propensity scoring methods to match subjects with (cases) or…
- Trial name
- ICONIC (NCT02959099)
- Where
- 13 sites in United States, Austria and 6 more
- Volunteers
- 476 people
- Sponsor
- Weill Medical College of Cornell University
Enhancement of Aorta and Pulmonary Artery, Radiation Exposure
The Best Parameters for Imaging Agent Injection and Scanning Methods in Computed Tomography Angiography
Background: The contrast time-enhancement profiles of pulmonary artery (PA) and the aorta differ by using computed tomography (CT) angiography.
- Trial name
- NCT04832633
- Testing
- Different contrast media injection methods
- Where
- Taiwan
- Volunteers
- 101 people
- Sponsor
- Mackay Memorial Hospital
Nerve Compression Syndrome, Abdominal Pain
Visualizing ACNES and LUCNES With DIRT
Anterior cutaneous nerve entrapment syndrome (ACNES) is caused by nerve entrapment in the abdominal wall. Recently de Weerd and Weum have suggested lumbar cutaneous nerve entrapment syndrome (LUCNES) as a name for a similar…
- Conditions
- Nerve Compression Syndrome, Abdominal Pain, Lower Back Pain
- Trial name
- NCT05080452
- Testing
- Dynamic infrared thermography (DIRT)
- Where
- Norway
- Volunteers
- 50 people
- Sponsor
- University Hospital of North Norway
Arteriosclerosis of Arterial Coronary Artery Bypass Graft
Long Term Follow-up of Open Versus Endoscopic Radial Artery Harvest With CT Angiography
The objectives of the study are two-fold: 1. To determine the mean 5 year patency rate of the radial artery graft (Open vs. Endoscopic) of patients who have already had CABG surgery and who previously participated in the centre's…
- Trial name
- NCT01559376
- Where
- 2 sites in Canada
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Coronary Artery Disease
Assessment of Patients With Suspected Coronary Artery Disease (CAD): What is the Best Initial Imaging Strategy?
Patients who present with chest pain are investigated with tests designed to confirm or exclude the presence of Coronary Artery Disease (CAD), as well as determine risk of poor outcome.
- Trial name
- IMAGE-CAD (NCT01668290)
- Where
- Canada
- Volunteers
- 173 people
- Sponsor
- Harald Becher
Coronary Artery Disease
Risk Evaluation by COronary CTA and Artificial IntelliGence Based fuNctIonal analyZing tEchniques - II
This study is a multicenter, prospective clinical cohort study. The study intends to continuously enroll patients with coronary heart disease.
- Trial name
- RECOGNIZE-II (NCT05856110)
- Where
- 9 sites in China
- Volunteers
- 2,000 people
- Sponsor
- Ruijin Hospital
Acute Coronary Syndromes
High-risk Features of Coronary Lesions in CTA and OCT
This study is a multicenter and retrospective study. ACS patients who underwent CCTA or OCT from 1 months to 3 years prior to the event will be retrospectively identified.
- Trial name
- NCT06089343
- Testing
- Coronary CT angiography
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Shanghai Zhongshan Hospital
Pulmonary Artery Embolism, Pulmonary Embolism (PE)
Repositioning the Bolus Tracking ROI to the Superior Vena Cava in CTPA Facilitates Contrast Volume Reduction
This randomized controlled trial evaluates a protocol optimization for Computed Tomography Pulmonary Angiography (CTPA). The study investigates the impact of repositioning the bolus-tracking region-of-interest (ROI) from the…
- Trial name
- NCT07342374
- Testing
- Optimized CTPA Protocol
- Where
- Malaysia
- Volunteers
- 72 people
- Sponsor
- Hospital Queen Elizabeth, Malaysia
Cardiovascular Diseases, Kidney Transplant; Complications
Cardiovascular Risk Assessment For Kidney Transplantation - Utility of Computed Tomography Coronary Angiography in the Assessment of Patients Awaiting Kidney Transplantation
Cardiovascular disease (for example, heart attack, stroke, heart failure) is the commonest complication of kidney failure. Kidney transplantation reduces cardiovascular risk but cardiovascular disease remains the commonest cause…
- Trial name
- CRAFT-CTCA (NCT06234410)
- Testing
- Computed tomography coronary angiography (CTCA)
- Where
- 2 sites in United Kingdom
- Volunteers
- 332 people
- Sponsor
- University of Edinburgh
Coronary Artery Disease
Augmented-Reality CTA Plus Angiography vs Angiography Alone for Guiding PCI in Coronary Lesions - Randomized Study
The purpose of this study is to compare revascularization strategy and its immediate results after augmented-reality computed tomography angiography (CTA) guided vs.
- Trial name
- AR-PCI (NCT03531424)
- Testing
- Angiographic guided PCI, Augmented-Reality CTA guided PCI
- Where
- Netherlands
- Volunteers
- 60 people
- Sponsor
- Paul Knaapen
Coronary Artery Disease
A Study of Computed Tomography (CT) for Evaluation of Coronary Artery Blockages in Typical or Atypical Chest Pain
To compare computed tomography (CT) images (pictures) of the coronary arteries using the General Electric (GE) LightSpeed VCT scanner with x-ray coronary angiography in patients with typical or atypical chest pain suspected of…
- Trial name
- NCT00348569
- Testing
- 64 Channel VCT
- Where
- United States
- Volunteers
- 245 people
- Sponsor
- GE Healthcare