Clinical trials: Computed Tomography Angiography
Coronary Artery Disease
Determination of Fractional Flow Reserve by Anatomic Computed Tomographic Angiography
This is a prospective, multi-center trial conducted at up to 20 US, Canadian, European and Asian centers designed to determine the diagnostic performance of CT-FLOW (the investigational technology) by coronary computed…
- Trial name
- DeFACTO (NCT01233518)
- Testing
- FFR
- Where
- United States
- Volunteers
- 285 people
- Sponsor
- HeartFlow, Inc.
Coronary Artery Disease
Xenetix® 350: Comparative Assessment of Image Quality for Coronary CT Angiography
The purpose of this study is to demonstrate the (statistical) non-inferiority of iobitridol (Xenetix® 350) when compared to contrast agents with higher iodine concentrations, iopromide (Ultravist® 370) and iomeprol (Iomeron® 400)…
- Trial name
- X-ACT (NCT01255722)
- Testing
- iobitridol, iopromide, iomeprol
- Where
- 23 sites in France, Germany and 3 more
- Volunteers
- 468 people
- Sponsor
- Guerbet
Myocardial Infarction, Coronary Artery Disease
PET/CT Study in the Diagnosis of Coronary Plaque
This study is being done to determine if a picture taking test of the heart, positron emission tomography/computed tomography (or cardiac PET/CT), can identify the blockages in the heart arteries that lead to heart attacks when…
- Conditions
- Myocardial Infarction, Coronary Artery Disease, Cardiac Catheterization
- Trial name
- PET/CT (NCT00850473)
- Testing
- PET/CT
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Washington University School of Medicine
Atherosclerosis
Rivaroxaban Versus Warfarin in the Evaluation of Progression of Coronary Calcium
Current oral anti-coagulation for atrial fibrillation is most commonly performed with warfarin. Warfarin is a vitamin K antagonist that has been shown in non-randomized trials to increase vascular calcification.
- Trial name
- NCT02376010
- Testing
- rivaroxaban, Warfarin
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center
Liver Blood Supply
3T MR Angiography of the Hepatic Vasculature
This study plans to learn more about the two Magnetic Resonance Angiography (MRA) techniques.
- Trial name
- NCT02299934
- Testing
- Magnetic Resonance Imaging (MRI), Compurtized Tomgraphy (CT)
- Volunteers
- 13 people
- Sponsor
- University of Colorado, Denver
Coronary Artery Disease
Screening For Asymptomatic Obstructive Coronary Artery Disease Among High-Risk Diabetic Patients Using CT Angiography, Following Core 64
Patients with a known history of diabetes mellitus and no prior documented evidence of cardiovascular disease will be evaluated for inclusion in the study.
- Trial name
- faCTor-64 (NCT00488033)
- Testing
- CT Angiography
- Where
- United States
- Volunteers
- 900 people
- Sponsor
- Intermountain Health Care, Inc.
Thoracic Aortic Aneurysm
Thoracoabdominal Arortic CTA Study
The purpose of this study is to compare the contrast agents and imaging techniques used for thoracoabdominal aortic imaging in CT.
- Trial name
- NCT02291718
- Testing
- Isovue
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Duke University
Arteriovenous Malformations
Treating Arteriovenous Malformation With Stereotactic Radiosurgery Using CT Angiography for Treatment Planning
Evaluate whether a treatment plan based on CT angiography can accurately and precisely identify the target nidus as compared to standard cerebral arteriography fused to MRI.
- Trial name
- NCT03559556
- Testing
- CT angiography
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- University of Texas Southwestern Medical Center
Coronary Artery Disease
Deep-Learning Image Reconstruction in CCTA
Cardiac CT allows the assessment of the heart and of the coronary arteries by use of ionising radiation. Although radiation exposure was significantly reduced in recent years, further decrease in radiation exposure is limited by…
- Trial name
- NCT03980470
- Testing
- TrueFidelity
- Where
- Switzerland
- Volunteers
- 50 people
- Sponsor
- University of Zurich
Coronary Artery Disease
Comparison of DSCT With IB-IVUS and Angiography in the Assessment of Coronary Artery Disease
The purpose of this study is to compare different methods of looking at atherosclerotic plaques in heart arteries. Identifying the characteristics of these plaques noninvasively would be very valuable.
- Trial name
- NCT00622167
- Testing
- Integrated Backscatter IVUS, Dual Source Computed Tomography
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Massachusetts General Hospital
Coronary Heart Disease, Coronary Artery Disease
Cardiogoniometry for Detecting Coronary Artery Disease by CT Angiography
Cardiogoniometry is a technique to process and evaluate vectorcardiography from regular ECG acquisitions. Vectorcardiography has a long tradition in cardiology for providing comprehensive information on myocardial function and…
- Conditions
- Coronary Heart Disease, Coronary Artery Disease, Ischemic Heart Disease
- Trial name
- NCT02725671
- Testing
- Explorer
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Johns Hopkins University
Coronary Artery Disease
Clinical Impact of Cardiac Photon-Counting Detector CT
The purpose of this research trial is to determine whether images taken using a Photon Counting Detector CT scanner (PCD-CT) provide clinically important information about the severity of suspected coronary artery disease and…
- Trial name
- NCT05240807
- Testing
- Photon-counting detector computed tomography (PCD-CT)
- Where
- United States
- Volunteers
- 276 people
- Sponsor
- Mayo Clinic
Coronary Artery Disease
Effects of Sublingual and Transdermal Administration of Nitroglycerin for Coronary CT Angiography on Image Quality
To evaluate image quality of coronary CT angiography (cCTA) after sublingual and transdermal administration of Nitroglycerin. Aim of this prospective research study is to investigate equivalence on image quality after sublingual…
- Trial name
- NCT02961946
- Testing
- Nitroglycerin
- Where
- United States
- Volunteers
- 198 people
- Sponsor
- Massachusetts General Hospital
Heart Disease, Coronary, Chest Pain
The Computed Tomography-derived Fractional Flow Reserve STAT Trial
This study is designed to directly compare Standard Care and CT fractional flow reserve (CTFFR) for diagnosis of chest pain patients with definite coronary artery disease (CAD) on heart computed tomography (CT) scans.
- Conditions
- Heart Disease, Coronary, Chest Pain, Acute Coronary Syndrome
- Trial name
- CTFFR-STAT (NCT03263806)
- Testing
- CTFFR-Guided Group Management, SOC Group Management
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Corewell Health East
Coronary Artery Disease
Stress CT Perfusion in Patients With Chest Pain
Our hypothesis is that quantitative 3D analysis of cardiac CT images obtained during vasodilator stress can accurately identify patients presenting at the emergency department with acute chest pain due to underlying…
- Trial name
- NCT01969916
- Testing
- Regadenoson
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- University of Chicago