Clinical trials: Computer-aided Diagnosis
Pathologic Processes, Disease
Diagnostic Reasoning With Customized GPT-4 Model
This study will assess the impact of immediate access to a customized version of GPT-4, a large language model, on performance in case-based diagnostic reasoning tasks.
- Trial name
- NCT06911645
- Testing
- Immediate access to customized version of GPT-4, Access to customized version of GPT-4 following use of conventional resources
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Stanford University
Cleft Lip and Palate
Use of Computer Aided Design and 3D Printing for Anesthesiology Management in a Pediatric Patient With Cleft Facial Defect (3D Obturator) - Pilot Trial
Congenital malformations of the orofacial area are the most common congenital malformations in children with an incidence of 1.8 children with orofacial cleft per 1000 healthy births in the Czech Republic.
- Trial name
- Pilobtur (NCT04422964)
- Testing
- 3D Obturator
- Where
- Czechia
- Volunteers
- 40 people
- Sponsor
- Brno University Hospital
Ovarian Cancer
CADx - Radiomics to Distinguish the Origin of Ovarian Tumors
In women with an ovarian tumor, it is often unclear whether the tumor is benign or malignant. To differentiate, tumor markers (CA125 and CEA), a transvaginal ultrasound and, depending on the ultrasound image and the CA125…
- Trial name
- CADx (NCT05174377)
- Testing
- CT-scan algorithm
- Where
- 5 sites in Netherlands
- Volunteers
- 600 people
- Sponsor
- Gynaecologisch Oncologisch Centrum Zuid
Pulmonary Fibrosis, Interstitial Lung Disease
Retrospective Validation of AccuPulmo CT Portal for Detecting Pulmonary Fibrosis on Chest CT
This retrospective observational study evaluates the diagnostic performance of AccuPulmo CT Portal, an artificial intelligence-assisted medical imaging software, for detecting pulmonary fibrosis on pre-existing chest computed…
- Trial name
- ACCUPULMO-FIBR (NCT07761377)
- Testing
- AccuPulmo CT Portal
- Where
- Taiwan
- Volunteers
- 900 people
- Sponsor
- Taichung Veterans General Hospital
Breast Cancer
Case Collection Study for Collecting Images for the Development and Validation of Computer Aided Detection Software
The study objective is to assess the performance of the MammoDetector Pro to correctly mark biopsy-proven breast cancers imaged on the Siemens Mammomat Novation FFDM system compared to conventional film-screen mammography.
- Trial name
- NCT00756834
- Testing
- Screening
- Where
- United States
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- Siemens Medical Solutions
Ventilation, ARDS
Respiratory Knowledge Portal Computer and Phone Application to Improve Quality of Mechanical Ventilation by Reducing the Number of Ventilator Associated Events, Injury Created by the Ventilator and Unsafe Setting of Alarms.
Ventilator associated events (VAE) is a quality metric defined by 48 hours of stability followed by 48 hours of escalation of ventilator settings within the ICU.
- Conditions
- Ventilation, ARDS, Respiratory Failure, Mechanical Ventilation
- Trial name
- NCT06737432
- Testing
- RKP Monitoring Software
- Where
- United States
- Volunteers
- 875 people
- Sponsor
- The University of Texas Medical Branch, Galveston
Polyps, Adenoma Colon
CADDIE Trial - Computer Aided Diagnosis and Detection for Intelligent Endoscopy
Background: Colonoscopy is accepted to be the gold standard for screening of colorectal cancer (CRC). Most CRCs develop from adenomatous polyps, with colonoscopy accepted to be the gold standard for screening of CRC.
- Conditions
- Polyps, Adenoma Colon, Colorectal Polyp, Colon Polyp
- Trial name
- CADDIE (NCT04325815)
- Testing
- CADDIE- Computer Aided (AI) Device used in Endoscopy
- Where
- United Kingdom
- Volunteers
- 739 people
- Sponsor
- University College, London
Malocclusion, Abnormalities, Jaw
Personalized Titanium Plates vs CAD/CAM Surgical Splints in Maxillary Repositioning of Orthognathic Surgery
The purpose of this study is to determine whether personalized titanium plates can achieve better accuracy than CAD/CAM surgical splint in maxilla repositioning in orthognathic surgery, and evaluate the feasibility of this…
- Trial name
- NCT02914431
- Testing
- 3D Printing Personalized Titanium Plate
- Where
- China
- Volunteers
- 64 people
- Sponsor
- Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University
Pneumoconiosis
Evaluation of Pneumoconiosis High Risk Early Warning Models
Precaution of pneumoconiosis is more important than treatment. However, the current process can't early warn the high-risk dust exposed workers until they are diagnosed with pneumoconiosis.
- Trial name
- NCT04952675
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Peking University Third Hospital
Colo-rectal Cancer, Polyp of Colon
Computer Aided Detection of Polyps During Colonoscopy Procedures
The focus of the study is to evaluate impact on Adenomas Per Colonoscopy (APC) with a Computer Aided Detection (CAD) software assisting the gastroenterologist during a colonoscopy procedure.
- Conditions
- Colo-rectal Cancer, Polyp of Colon, Adenomatous Polyps
- Trial name
- NCT04195646
- Testing
- EndoVigilant CAD Software
- Where
- 2 sites in United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- EndoVigilant Inc
Prostate Cancer Diagnosis
PROVIZ - a Machine Learning Software, to Support Targeting of Prostate Biopsies on MR Images in Biopsy-naive Patients
To perform a traditional feasibility clinical investigation, as defined in ISO 14155:2020, to investigate preliminary feasibility, safety, and clinical performance information of a near-final design of the investigational…
- Trial name
- NCT06000046
- Testing
- Automatic image analysis
- Where
- Norway
- Volunteers
- 82 people
- Sponsor
- Norwegian University of Science and Technology
Pancreatitis
Abstats: Computer-aided, Non-invasive, Acoustic Gastrointestinal Surveillance (AGIS) in Acute Pancreatitis
The purpose of this study is to conduct a pilot test of an abdominal acoustic sensor on patients with acute pancreatitis to determine the correlation of acoustic signals with symptoms reported by the patient.
- Trial name
- NCT02412826
- Testing
- Abstats sensor
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Cedars-Sinai Medical Center
Colorectal Polyp, Colorectal Cancer
Computer-aided Detection During Screening Colonoscopy
Nowadays, colonoscopy is considered the gold standard for the detection of lesions in the colorectal mucosa. However, around 25% of polyps may be missed during the conventional colonoscopy.
- Conditions
- Colorectal Polyp, Colorectal Cancer, Colorectal Adenoma
- Trial name
- NCT05734820
- Testing
- HD- colonoscopy, HD-colonoscopy assisted by AI
- Where
- Ecuador
- Volunteers
- 312 people
- Sponsor
- Instituto Ecuatoriano de Enfermedades Digestivas
Colon Polyp
Computer Aided Diagnosis of Colorectal Neoplasms During Colonoscopic Examination
An NBI-based diagnosis requires training and experience. We are developing a system of computerized image recognition, which can detect possible NBI features of polyps, and provide a more objective diagnosis, which allows…
- Trial name
- NCT03069833
- Testing
- Computer-aided diagnosis
- Where
- Taiwan
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Tri-Service General Hospital (TSGH)
Tooth Erosion, Teeth Erosion Due to Vomiting
Clinical Evaluation of Ultrathin Occlusal Veneers for the Treatment of Severe Dental Erosion
Ultra-thin bonded posterior occlusal veneers represent a conservative alternative to traditional onlays and complete coverage crowns for the treatment of severe erosive lesions.
- Conditions
- Tooth Erosion, Teeth Erosion Due to Vomiting, Teeth Erosion Limited to the Enamel, Teeth Erosion Extending Into the Dentine
- Trial name
- UOVTDE (NCT03112278)
- Testing
- Ceramic ultrathin occlusal veneers, Composite resin ultrathin occlusal veneers
- Volunteers
- 10 people
- Sponsor
- Universidade Federal do Rio de Janeiro
Glioma, Glioma (Diagnosis)
AI-driven Processing and Analysis of Glioma Imaging Data
GLIOMAID is a scientific research project focused on improving how brain tumors, specifically gliomas, are diagnosed and managed. It uses Artificial Intelligence (AI) to analyze MRI brain scans and patient data.
- Trial name
- GLIOMAID (NCT07703761)
- Testing
- AI-driven analysis of brain MRI data for early, non-invasive detection, segmentation, and histological characterization of gliomas using retrospective clinical and imaging records.
- Where
- Italy
- Volunteers
- 700 people
- Sponsor
- Università degli Studi di Trento
Airway Disease
Treatment of Central Airway Stenoses Using Computer-Assisted Customized 3d Stents TATUM
Airway stenting is usually efficient to treat central airway obstruction but can lead to severe and potentially lethal complications (stent migration, obstructive granuloma, perforation, and hemoptysis).
- Trial name
- TATUM (NCT04848025)
- Testing
- Custom-designed tracheobronchial prostheses
- Where
- France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Toulouse
Osteogenic Sarcoma
Accuracy of Deep-learning Algorithm for Detection and Risk Stratification of Lung Nodules
Osteosarcoma is regarded as most common malignant bone tumor in children and adolescents. Approximately 15% to 20% of patients with osteosarcoma present with detectable metastatic disease, and the majority of whom (85%) have…
- Trial name
- NCT04022512
- Testing
- computed tomography
- Where
- Hong Kong
- Volunteers
- 100 people
- Sponsor
- Chinese University of Hong Kong
Cleft Lip and Palate
Evaluation of the Clinical Effectiveness of Naso-alveolar Molding (NAM) Versus Computer Aided Design NAM (CAD/NAM) in Infants With Bilateral Cleft Lip and Palate: A Randomized Clinical Trial
Bilateral cleft lip and palate neonates will be randomly assigned to one of two groups: (gp1 presurgical Naso-alveolar molding (NAM) using Grayson method, gp 2 computer aided design NAM (CAD/NAM).
- Trial name
- NCT02881606
- Testing
- Naso-alveolar molding (NAM), Computer aided design NAM (CAD/NAM)
- Where
- Egypt
- Volunteers
- 28 people
- Sponsor
- Cairo University
Colonic Adenoma, Colonic Polyp
Endocuff With or Without AI-assisted Colonoscopy
Colonoscopy is considered the gold standard for diagnosis of colonic polyps. However, it was reported that colonoscopy could still miss colonic polyps. Many attempts have been made to improve the detection rate of colonoscopy.
- Conditions
- Colonic Adenoma, Colonic Polyp, Colonic Cancer
- Trial name
- NCT05133544
- Testing
- Endocuff with AI, AI alone
- Where
- Hong Kong
- Volunteers
- 656 people
- Sponsor
- The University of Hong Kong