Clinical trials: Concentration
Chronic Kidney Disease
Study of the Influence of Liver Function on Blood Concentrations of Runcaciguat in Participants With Different Degrees of Liver Impairment
Researchers are looking for a better way to treat people with chronic kidney diseases. Before a treatment can be approved for patients to take, researchers do clinical studies to better understand its safety and what happens to…
- Trial name
- NCT04820621
- Testing
- Runcaciguat (BAY1101042)
- Where
- Germany
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Bayer
Attention Deficit Disorder With Hyperactivity
Working Memory Training in Young ADHD Children
The purpose of this study is to investigate whether working memory training improves behavioral symptoms, neurocognitive performance, and neural functioning in young children with ADHD.
- Trial name
- NCT00819611
- Testing
- Cogmed Working memory training, Control version of Cogmed working memory training
- Where
- Netherlands
- Volunteers
- 51 people
- Sponsor
- Radboud University Medical Center
Attention, Memory
The Impact of Supplementation With Hericium Erinaceus (Lion's Mane) Extract on Cognitive Functioning
The goal of this study is to determine whether supplementation with Hericium erinaceus (Lion's Mane) extract enhances selected cognitive functions in healthy, actively working, middle-aged women.
- Conditions
- Attention, Memory, Cognitive Function and Well-Being
- Trial name
- HECOG (NCT07405632)
- Testing
- Hericium erinaceus Supplementation
- Where
- Poland
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- University of Social Sciences and Humanities, Warsaw
Attention Deficit Hyperactivity Disorder
Lisdexamfetamine's Effect In ADHD in the Brain and Cognition
The purpose of this study is to identify the effects of lisdexamfetamine (LDX) on the neural and behavioral subcomponents of self-control, that is cognitive control and reward functioning, in adolescents and young adults with…
- Trial name
- LEIA (NCT02170298)
- Testing
- Lisdexamfetamine
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- University of California, Davis
Attention Deficit Hyperactivity Disorder
Adults With Attention Deficit Hyperactivity Disorder (ADHD): Validation of a Clinical Interview and Screening Instruments in French
ADHD is a neurodevelopmental disorder that affects about 5% of school-age children and 3.5% of adults worldwide. This condition is under-recognised in France and other European countries and, therefore, under-diagnosed.
- Trial name
- NCT01553695
- Testing
- questionary
- Where
- France
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Nice
Affective Disorders, Anxiety Disorders
Cognitive Skills Training for Homeless Youth
Many young people who are homeless have cognitive deficits which impede their ability to secure and maintain employment. This study looks to see if targeting cognitive deficits can improve cognition and vocational outcome.
- Conditions
- Affective Disorders, Anxiety Disorders, Attention Deficit Disorder, Substance Abuse
- Trial name
- NCT01815398
- Testing
- Cognitive Remediation, Computer Skills Training
- Where
- United States
- Volunteers
- 188 people
- Sponsor
- New York State Psychiatric Institute
Healthy
A Study of Lazertinib (JNJ-73841937) in Healthy Participants
The purpose of this study is to evaluate the effect of steady-state concentrations of lazertinib on the single-dose pharmacokinetics (PK) of probe substrates (midazolam, rosuvastatin, and metformin) in healthy adult participants.
- Trial name
- NCT05076877
- Testing
- Lazertinib, Midazolam, Rosuvastatin
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Janssen Research & Development, LLC
Psoriasis, Colitis, Ulcerative
A Remotely Conducted Study to Assess Concentration of TREMFYA in Breast Milk of Lactating Women Who Are Receiving TREMFYA Therapeutically
The purpose of this post-marketing study is to assess the amount of guselkumab in breast milk of lactating women receiving guselkumab as part of their standard clinical care provided by their treating physician, for any of the…
- Conditions
- Psoriasis, Colitis, Ulcerative, Crohn Disease, Arthritis, Psoriatic
- Trial name
- NCT07654751
- Testing
- Breast Milk Sample Collection, Guselkumab
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Janssen Research & Development, LLC
ADHD, ADD
Intervention With Omega-3 in Children With Attention Deficit Hyperactivity Disorder(ADHD)
This study aims to determine if marine monounsaturated and polyunsaturated fatty acids can benefit children aged 6-16 years with ADHD and related symptoms.
- Trial name
- NCT02986672
- Testing
- Calanus oil, Medical Paraffin
- Where
- 2 sites in Norway
- Volunteers
- 332 people
- Sponsor
- University Hospital of North Norway
Ankylosing Spondylitis
Optimal Adalimumab Plasma Concentrations in Ankylosing Spondylitis Patients
The optimal plasma concentration range of adalimumab in Chinese patients with active ankylosing spondylitis remains unknown, the aims of this study is to determine the concentration-effect relationship, and explore the effect of…
- Trial name
- NCT04875299
- Testing
- The study is observational
- Where
- China
- Volunteers
- 480 people
- Sponsor
- The First Affiliated Hospital of Soochow University
Staphylococcus Aureus Infection
Study of the Nasal Decolonisation of Staphylococcus Aureus (SA) and the Safety and Tolerability of XF-73 Nasal Gel in Healthy Subjects
Study to determine the efficacy, safety and tolerability of two concentrations of XF-73 nasal gel in combination with body and face washing with chlorhexidine gluconate cloths in eradicating nasal carriage of Staphylococcus…
- Trial name
- NCT02282605
- Testing
- XF-73 nasal gel, Chlorhexidine gluconate 2% topical cloths
- Where
- United Kingdom
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Destiny Pharma Plc
Sevoflurane, Endotracheal Intubation
Effect of Head Position on MACEI of Sevoflurane in Children With Obstructive Airway
Children scheduled for tonsillectomy surgery were recruited into the study. General anesthesia was induced with 8% sevoflurane inhaled with 8 l.min-1 of oxygen via mask, followed by adjustment of inspired sevoflurane to the…
- Trial name
- MACEI (NCT03522402)
- Testing
- Sevoflurane
- Where
- China
- Volunteers
- 38 people
- Sponsor
- Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University
Attention Deficit Hyperactivity Disorder
Carnitine as an Adjunct to Methylphenidate for the Treatment of Attention Deficit Hyperactivity Disorder
Attention-deficit hyperactivity disorder (ADHD) is the most common neurobehavioural disorder of childhood. The investigators hypothesized that carnitine would be beneficial for treatment of ADHD, and this could be evaluated in a…
- Trial name
- NCT01099072
- Testing
- methylphenidate+carnitine
- Where
- Iran
- Volunteers
- 40 people
- Sponsor
- Tehran University of Medical Sciences
Coughing
Fractional Concentration of Exhaled NO(FENO) to Direct Montelukast Treatment of Sub-acute Cough
Cough is a common symptom of respiratory medicine clinic patients, which has complex etiology and wide-ranging. Cough is usually divided into three categories by time: acute cough, subacute cough and chronic cough.
- Trial name
- NCT02303600
- Testing
- Montelukast
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Beijing Chao Yang Hospital
Cardiovascular Diseases
The Acute Effect of 2 Different Serving Regimens of Theobromine on Physiological Effects
The main aim of this study is to determine whether there is a difference in the physiological effects of theobromine when provided via a single serving compared to multiple servings adding up to the same amount of theobromine…
- Trial name
- NCT01544829
- Testing
- Theobromine
- Where
- France
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Unilever R&D
Anesthesia
A Modeling of Changes in Tidal Volume With Concentration of Inhalational Anesthetics
modelling of tidal volume with inhalational anesthetic concentration
- Trial name
- NCT03491839
- Where
- South Korea
- Volunteers
- 50 people
- Sponsor
- Seoul National University Hospital
Adult Attention Deficit Hyperactivity Disorder
Duration and Efficacy of Azstarys on Adult ADHD Symptoms and Executive Function in Early Evening
This is a single-site study. One purpose of this trial is to extend the safety and efficacy evidence basis for Azstarys in adults with ADHD.
- Trial name
- NCT06000501
- Testing
- Serdexmethylphenidate/dexmethylphenidate
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- NYU Langone Health
Cigarette Smoking
Experimental Tobacco Marketplace in Regulating Flavored Tobacco Products in Menthol Cigarette Smokers
This trial uses an Experimental Tobacco Marketplace to study the purchase of tobacco products in menthol cigarette smokers. Determining the level of substitutability of both flavored and unflavored/tobacco flavored e-cigarettes…
- Trial name
- NCT03897530
- Testing
- Smoking Cessation Intervention, Functional Assessment, Questionnaire Administration
- Where
- United States
- Volunteers
- 103 people, healthy volunteers welcome
- Sponsor
- Roswell Park Cancer Institute
Attention Deficit Disorder With Hyperactivity
Children's Attention Deficit Disorder With Hyperactivity (ADHD) Telemental Health Treatment Study
While telemental health (TMH) programs are increasing nationally to address the inequity of access to psychiatric services, there are few reports of their efficacy, particularly with children.
- Trial name
- CATTS (NCT00830700)
- Testing
- CATMH intervention
- Where
- United States
- Volunteers
- 223 people
- Sponsor
- Seattle Children's Hospital
Attention Deficit Disorder, Hyperactivity Disorder
Neural Mechanisms of Attention Lapses in Adult ADHD
ADHD is a common disorder, leading to a significant disability that often persists in adulthood. ADHD is characterized by attentional disturbances that are difficult to asses with standard neuropsychological tests.
- Trial name
- AttLapse-TDA (NCT03948607)
- Testing
- Electroencephalography during sustained attention task.
- Where
- France
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- University Hospital, Strasbourg, France
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