Clinical trials: Concentration
ADHD, Disruptive Behaviours
Biosignatures for the Development of Attention Deficit Hyperactivity Disorder
As an exploratory aim of this grant, we examined the extent to which a comprehensive psychosocial intervention conducted in the summer can improve young children with disruptive behavior challenges as it relates to their…
- Trial name
- AHEAD (NCT07381855)
- Testing
- Summer treatment program for children transitioning to and from kindergarten (STP-K)
- Volunteers
- 323 people, healthy volunteers welcome
- Sponsor
- Florida International University
Alcohol Abuse, Cognitive Deficit in Attention
Pilot Study on Training Emerging Adults Skills in Navigating College
Lifetime risk for developing an alcohol use disorder increases with earlier onset of alcohol consumption. This risk may reflect a tendency for escalated alcohol intake among youth due to immature executive control, leading to…
- Trial name
- SINC (NCT05560425)
- Testing
- Koru Mindfulness (KM) Training, Navigating College (NC) Training
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Acetaminophen-protein Adduct Formation
Acetaminophen-Protein Adduct Resolution
The purpose of this study is to better understand the pharmacokinetics of acetaminophen and further clinical interpretations of laboratory results that confirm the presence of acetaminophen-cys adducts.
- Trial name
- AR (NCT01021410)
- Where
- 2 sites in United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Denver Health and Hospital Authority
Attention Deficit Disorder With Hyperactivity
A Safety and Effectiveness Study of Methylphenidate HCl Extended-release Tablets in Adults With Attention Deficit Hyperactivity Disorder
The purpose of this study is to evaluate the effectiveness and safety of methylphenidate HCl extended-release tablets at five dose levels compared to placebo in adults with Attention Deficit Hyperactivity Disorder (ADHD)
- Trial name
- NCT00326391
- Testing
- methylphenidate hydrochloride extended-release tablets
- Volunteers
- 229 people
- Sponsor
- McNeil Consumer & Specialty Pharmaceuticals, a Division of McNeil-PPC, Inc.
Phenylketonuria
Phase 2 Study of Glycomacropeptide Versus Amino Acid Diet for Management of Phenylketonuria
For individuals with Phenylketonuria (PKU), the investigators hypothesize that glycomacropeptide will provide an acceptable form of low-phenylalanine dietary protein that will improve dietary compliance, blood phenylalanine…
- Trial name
- PKU (NCT01428258)
- Testing
- GMP Diet/GMP Medical Foods, AA Diet/AA Medical Foods
- Where
- 2 sites in United States
- Volunteers
- 32 people
- Sponsor
- University of Wisconsin, Madison
Vision, Healthy
Experiment 2: One Target in Many Situations
The goal is to look for qualitative differences in visual search behavior when one search is performed many times in a row compared to when multiple search tasks are intermixed. Four search tasks are tested.
- Conditions
- Vision, Healthy, Attention
- Trial name
- NCT06934148
- Testing
- Blocked Trials, Mixed trials
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Schizophrenia, Psychopathology
fMRI Study of Nicotinic Effect on Neurophysiology of Schizophrenia
Background: Individuals who have schizophrenia are significantly more likely to smoke than the general population, which leads to increased smoking-related illnesses and high rates of nicotine dependence.
- Conditions
- Schizophrenia, Psychopathology, Nicotine Dependence
- Trial name
- NCT01046526
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- National Institute on Drug Abuse (NIDA)
Adult ADHD
Emotional Dysregulation in Adult ADHD.
Attention deficit disorder in adults with or without hyperactivity (ADHD) is a common disorder, affecting around 3% of the population.
- Trial name
- EMO-TDA (NCT03494478)
- Testing
- Neuropsychological testing, Actimetry, Self-questionnaires on emotional topics
- Where
- 2 sites in France
- Volunteers
- 120 people
- Sponsor
- University Hospital, Strasbourg, France
Attention Deficit Disorder With Hyperactivity, Attention Deficit Disorder Without Hyperactivity
Emotional Information Processing in Attention Deficit Disorder With or Without Hyperactivity
The aim of this study is to analyse explicit and implicit emotional information processing abilities in children with attention deficit disorder with or without hyperactivity
- Trial name
- TIVE-TDA (NCT03861585)
- Testing
- Semantic group, Emotional group
- Where
- France
- Volunteers
- 54 people
- Sponsor
- Fondation Lenval
Pneumococcal Meningitis
Vancomycin Concentration in Cerebrospinal Fluid During Pneumococcal Meningitis
Adding vancomycin to the antibiotic regimen is recommended for the treatment of pneumococcal meningitis in adults. Use of dexamethasone as adjunct therapy has proved to reduce mortality and neurologic sequelae in adult patients…
- Trial name
- NCT00162578
- Where
- 3 sites in France
- Volunteers
- 14 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Attention Deficit Hyperactivity Disorder
Atomoxetine to Treat Korean Children and Adolescents With Attention-Deficit/Hyperactivity Disorder (ADHD)
The purpose of this study is to provide information regarding the relative effectiveness of three different atomoxetine doses in the treatment of Korean children and adolescents with Attention-Deficit/Hyperactivity Disorder (ADHD)
- Trial name
- NCT00568685
- Testing
- Atomoxetine Hydrochloride
- Where
- 3 sites in South Korea
- Volunteers
- 153 people
- Sponsor
- Eli Lilly and Company
TBI (Traumatic Brain Injury)
The Development of a Virtual Reality Program to Improve Attention in Individuals With TBI
The purpose of this research is to investigate the effectiveness of a technique designed to improve divided attention and set-shifting impairments in persons with a traumatic brain injury (TBI).
- Trial name
- NCT03605017
- Testing
- Virtual Reality Executive Function Training (VREFT)
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Kessler Foundation
Mental Fatigue, Cognitive Performance
Predicting Declines in Attention and Memory During a Prolonged Mental Task
This study will investigate whether heart activity and changes in the skin's ability to conduct electricity can help predict performance during a demanding computer task.
- Trial name
- COG-PRED (NCT07877389)
- Testing
- Individually Calibrated Time Load Dual-back Task With Seated Rest
- Where
- Poland
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- DSW Ideis University
Cervical Myelopathy, Radiculopathy
Bone Marrow Aspirate Concentration in Posterior Cervical Fusion
The purpose of this research is to test if that combining bone marrow aspirate (removing bone marrow with a needle) concentration with locally harvested (collected) autograft (patient's own bone from another part of the body) for…
- Trial name
- BMAC (NCT02068547)
- Testing
- locally harvested autograft, demineralized bone matrix, and cadaveric allograft, Bone Marrow Aspirate
- Where
- 2 sites in United States
- Volunteers
- 8 people
- Sponsor
- Washington University School of Medicine
Attention Deficit Hyperactivity Disorder
Effects of HIIT VR Exergame on Attention and Executive Function in Young People With ADHD
The goal of this clinical trial is to learn if the "Move Sapiens" exergame in Virtual Reality (VR), incorporated with a short model of High-Intensity Interval Training (HIIT), works as an intervention tool for adolescents with…
- Trial name
- VRADHD (NCT06632249)
- Testing
- Practice with the virtual reality game
- Where
- 2 sites in Brazil
- Volunteers
- 98 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Attention Deficit Disorder With Hyperactivity (ADHD)
ADHD Medication and Predictors of Treatment Outcome
ADHD medication of children and adolescents is becoming increasingly common. Clinical experience and scientific studies have proven that approximately 30% of children/adolescents with ADHD do not benefit from this treatment.
- Trial name
- ADAPT (NCT02136147)
- Testing
- methylphenidate medication, atomoxetine medication, lisdexamphetamine medication
- Where
- Sweden
- Volunteers
- 632 people
- Sponsor
- Karolinska Institutet
Gestational Age
Urine and Serum Concentrations of Pregnancy-Associated Compounds During Gestation
Investigators will collect serum and urine specimens from pregnant patients along the full pregnancy continuum, assay each specimen for selected placental proteins, and examine the relationships between concentrations of the…
- Trial name
- NCT03552055
- Testing
- Non-interventional Study
- Where
- 2 sites in United States
- Volunteers
- 245 people
- Sponsor
- Gynuity Health Projects
Hypertension
The Effect of Beetroot Juice on Plasma Trimethylamine N-oxide Concentration
The primary aim of the current study is to determine the effect of beetroot juice consumption on plasma trimethylamine N-oxide concentration.
- Trial name
- BRJ_TMAO (NCT05004935)
- Testing
- beetroot juice, nitrate
- Where
- Poland
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Poznan University of Physical Education
Attention Deficit Hyperactivity Disorder (ADHD)
The MEASURE Study - A Phase 3 Study of MDX 1400 mg Daily Compared With Placebo in Adults With ADHD
This study is a multi-center, randomized, double-blind, placebo-controlled, phase 3 study of MDX (1400 mg daily) for 10 weeks compared with placebo in adults with ADHD.
- Trial name
- NCT02477748
- Testing
- MDX
- Where
- 38 sites in United States, Israel
- Volunteers
- 283 people, healthy volunteers welcome
- Sponsor
- Alcobra Ltd.
Menopause, Brain Activity
LDX and Functional Magnetic Resonance Imaging (fMRI in Menopausal Women
This study seeks to assess the effects of lisdexamfetamine (trademark name: Vyvanse; LDX) on executive function and prefrontal cortex activation in menopausal women ages 45-57, who report subjective cognitive difficulties.
- Conditions
- Menopause, Brain Activity, Cognition
- Trial name
- NCT01977625
- Testing
- Lisdexamfetamine
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
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