Clinical trials: Concentration
Caries
Total Salivary Fluoride Concentration of Healthy Adult Subjects Following Toothbrushing With Different Formulations of Fluoridated Toothpastes With and Without Post-brushing Water Rinsing.
Caries prevalence has declined significantly since the introduction of fluoridated toothpastes. Since then, different toothpaste formulations and concentrations have been introduced to the market with varying levels of efficacy.
- Trial name
- NCT02740803
- Testing
- Sodium fluoride toothpaste 1,450 ppmF, sodium monofluorophosphate toothpaste 1,450 ppmF, stannous fluoride combined with sodium fluoride toothpaste 1,450 ppmF
- Where
- United Kingdom
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Leeds
Healthy
The Effects of Vasopressin on Attention Control
The main aim of the present study is to investigate whether intranasal vasopressin (20IU) could influence attention control in a social-emotional saccade/antisaccade eye-tracking paradigm.
- Trial name
- NCT04493554
- Testing
- Vasopressin
- Where
- China
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- University of Electronic Science and Technology of China
Rotator Cuff Tear, Bone Marrow
Autologous Bone Marrow Concentration for Rotator Cuff Tear
This study aims to evaluate the effect of bone marrow concentration on healing of rotator cuff tear by comparing clinical and imaging outcomes between patients receiving arthroscopic repair with intraoperative bone marrow…
- Trial name
- NCT03792594
- Testing
- arthroscopic repair with bone marrow concentration, arthroscopic repair
- Where
- Taiwan
- Volunteers
- 40 people
- Sponsor
- Pei-Yuan Lee, MD
Attention Deficit Hyperactivity Disorder
Response Variability in Children With Attention Deficit Hyperactivity Disorder (ADHD)
Children with Attention Deficit Hyperactivity Disorder (ADHD) have numerous areas of neuropsychological dysfunction including response inhibition, working memory, and attention.
- Trial name
- NCT01238822
- Testing
- Methylphenidate
- Where
- United States
- Volunteers
- 96 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Rheumatoid Arthritis
Association Between Methotrexate Erythrocyte Polyglutamate Concentration and Biological Drug Concentration and Clinical Response in Rheumatoid Arthritis Patients Treated With Subcutaneous Injectable Methotrexate and a First Biological Drug
The combination of methotrexate (MTX) with a biological disease-modifying antirheumatic drugs (bDMARD) is the next step in treatment with MTX monotherapy in rheumatoid arthritis (RA).
- Trial name
- POLYbio (NCT04470453)
- Testing
- Blood sample, CRQ
- Where
- France
- Volunteers
- 16 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
ADHD
Placebo-Controlled Trial With GlyTI-M Among Children With Attention Deficit Hyperactivity Disorder (ADHD)
Although psychostimulant is the first line of drug to treat Attention Deficit Hyperactivity Disorder, (ADHD), actually there are 10-20% ADHD patient do not response well to current medication.
- Trial name
- NCT01725737
- Testing
- GlyTI-M
- Where
- Taiwan
- Volunteers
- 116 people
- Sponsor
- Mackay Memorial Hospital
Infertility
Assessment of Two Methods for Progesterone Dosage During IVF
Nowadays, 1/7 couple consult because of infertility and some of them will need in vitro fertilization +/- intracytoplasmic sperm injection (IVF+/- ICSI).
- Trial name
- SALIPROG (NCT05987657)
- Testing
- Salivary and blood progesterone dosage
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Hospices Civils de Lyon
Attention Deficit Disorder With Hyperactivity
Hyperactivity Assessment in Children With Attention-deficit Hyperactivity Disorder
Attention-deficit hyperactivity disorder (ADHD) is a neurodevelopmental disorder characterized by inattention, hyperactivity, and impulsivity.
- Trial name
- NCT05810636
- Testing
- Garmin Vivosmart wearable device
- Where
- Taiwan
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Cancer-related Problem/Condition, Cognitive Impairment
Memory and Attention Adaptation Training-Geriatrics (MAAT-G)
Cancer-related cognitive dysfunction (CRCD) affects up to 75% of patients receiving chemotherapy and older adults are at greater risk of developing CRCD, which can negatively affect their functional independence and quality of…
- Trial name
- NCT04230941
- Testing
- MAAT-G
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- University of Rochester
Childhood Disruptive Behavior Disorders, Oppositional Defiant Disorder
Child and Family Outcomes and Consumer Satisfaction for Online vs Staff-Delivered Parenting Intervention
This trial addresses a serious and all-too-frequent public health problem, namely early-onset disruptive behavior problems in young children.
- Conditions
- Childhood Disruptive Behavior Disorders, Oppositional Defiant Disorder, Conduct Disorder, Attention Deficit Hyperactivity Disorder
- Trial name
- TPAS (NCT02121431)
- Testing
- Triple P--Positive Parenting Program
- Where
- 2 sites in United States
- Volunteers
- 334 people
- Sponsor
- University of South Carolina
Attention-Deficit/Hyperactivity Disorder
Inflammation in Children With Attention-Deficit/Hyperactivity Disorder
The aim of this study is to investigate the inflammatory response in children with this disorder.
- Trial name
- ADHD_CYTO (NCT00391495)
- Testing
- Blood drawing
- Where
- Israel
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Tel-Aviv Sourasky Medical Center
ADHD
A Double Blind Randomized Controlled Evaluation of the HBLPADD-coil Transcranial Magnetic Stimulation (TMS) Device - Efficacy and Safety In Subjects With ADHD.
Objectives:The purpose of the study is to explore the efficacy and safety of HBLPADD Coil deep brain TMS in subjects with ADHD. Patient Population: The intention is to treat 40 patients diagnosed with ADHD.
- Trial name
- NCT01723319
- Testing
- HBLPADD coil deep TMS
- Where
- Israel
- Volunteers
- 40 people
- Sponsor
- Shalvata Mental Health Center
Adult Attention Deficit Hyperactivity Disorder
Researching the Effectiveness of Attexis, a Digital Health Application for Adults With Attention Deficit Hyperactivity Disorder
In this randomized controlled clinical trial, 326 patients with ADHD will be investigated regarding the effectiveness of a digital therapeutic for improved ADHD symptomatology, the unguided online intervention attexis.
- Trial name
- READ-ADHD (NCT06221930)
- Testing
- attexis
- Where
- Germany
- Volunteers
- 337 people
- Sponsor
- Gaia AG
Diquat Poisoning, Blood Purification
Leveraging Plasma Concentration Levels to Optimize Extracorporeal Treatment in Acute Diquat Poisoning
This study aimed to evaluate the clinical value of plasma diquat concentration in guiding personalized extracorporeal treatment regimens for patients with acute diquat poisoning.
- Trial name
- NCT06807151
- Testing
- Extracorporeal Treatment
- Where
- China
- Volunteers
- 163 people
- Sponsor
- The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
Blood Glucose Concentration, Blood Glucose Self Monitoring
Effect of Low Water Intake on Glucose Regulation Measured Using Continuous Glucose Monitoring
This clinical trial aims to learn if increasing water intake for five days can lower blood glucose in healthy, free-living individuals.
- Trial name
- NCT06645431
- Testing
- Water Intake
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- California Polytechnic State University-San Luis Obispo
Attention Deficit Hyperactivity Disorder, Neurodevelopmental Disorders
Treatment of ADHD Using High and Low Frequency Paired Associative Deep Transcranial Magnetic Stimulation
This study investigates the effects of high and low-frequency paired associative deep transcranial magnetic stimulation (dTMS) on adults with Attention Deficit Hyperactivity Disorder (ADHD).
- Conditions
- Attention Deficit Hyperactivity Disorder, Neurodevelopmental Disorders, Prefrontal Cortex Dysregulation, Cortical Arousal Imbalance
- Trial name
- NCT07105475
- Testing
- Paired Associative Transcranial Magnetic Stimulation (TMS)
- Where
- Israel
- Volunteers
- 90 people
- Sponsor
- Ben-Gurion University of the Negev
Measure of Nociception
Composite Variability Index and Propofol Remifentanil Anesthesia
The purpose of the study is to determine if the new Composite Variability Index (CVI) is capable of detecting changing effect compartment concentrations of remifentanil.
- Trial name
- NCT01234194
- Testing
- rising remifentanil concentrations, falling remifentanil concentrations
- Where
- Germany
- Volunteers
- 24 people
- Sponsor
- University Hospital, Bonn
Thiazide-induced Hyponatremia (TIH)
Urinary Prostaglandin as a Potential Predictive Marker for Thiazide-induced Hyponatremia
Thiazides and thiazide-like diuretics are one of the five major classes of antihypertensive drugs. This study is to investigate whether urinary PGE2 concentration at baseline (prior to thiazide initiation) is associated with the…
- Trial name
- PROPHECY (NCT05542056)
- Testing
- Data and biosample collection
- Where
- 3 sites in Spain, Switzerland
- Volunteers
- 232 people
- Sponsor
- University Hospital, Basel, Switzerland
Stroke, Action Speed
Diagnostic and Prognostic Value of New Quick Tests of Action Slowing in Stroke and in Cognitive Neurodegenerative Disease
A large series of recent studies have documented the frequency of the slowing of the action in brain diseases, especially vascular and neurodegenerative diseases.
- Conditions
- Stroke, Action Speed, Dementia Mild Cognitive Impairment, Alzheimer Disease
- Trial name
- QTOAS (NCT05785156)
- Testing
- quick tests
- Where
- France
- Volunteers
- 129 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Parkinson's Disease
A Safety, Tolerability, and Plasma Concentration Study of Levodopa/Carbidopa Subcutaneous Solution (ND0612) in Parkinson's Disease (PD) Patients
In this Phase I/IIa study, the effect of continuous subcutaneous administration of LD/CD solution (ND0612) on the safety and PK profile of LD will be examined.
- Trial name
- NCT01725802
- Testing
- Levodopa/carbidopa solution for SC administration
- Where
- Israel
- Volunteers
- 8 people
- Sponsor
- NeuroDerm Ltd.
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