Clinical trials: Concentration
HIV Infections
Cerebrospinal Fluid (CSF) Raltegravir Substudy
The purpose of this study is to measure concentrations of Raltegravir in cerebrospinal fluid. The hypotheses are: Raltegravir concentrations in CSF will be measurable Raltegravir concentrations in CSF will remain constant, while…
- Trial name
- NCT00718029
- Volunteers
- 4 people
- Sponsor
- University of California, San Diego
ADHD
A Peer-Delivered High School Preparatory Intervention for Students With ADHD
This study will test whether a peer-delivered intervention for high school students with ADHD outperforms enhanced school services as usual.
- Trial name
- Summer STRIPES (NCT04571320)
- Testing
- Summer STRIPES, Enhanced School Services as Usual
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- Seattle Children's Hospital
Chronic Kidney Failure, Graft vs Host Disease
Study Evaluating Sirolimus in End Stage Renal Disease in High Risk Kidney Transplant Recipients
The incidence of efficacy failure at 12 months between two regimens.
- Conditions
- Chronic Kidney Failure, Graft vs Host Disease, Kidney Transplantation
- Trial name
- NCT00044720
- Testing
- Rapamune
- Volunteers
- 484 people
- Sponsor
- Wyeth is now a wholly owned subsidiary of Pfizer
Attention-deficit/Hyperactivity Disorder
An Open-Label Treatment With Randomization Observation, Investigator-Initiated Study, on the Duration and Efficacy of Jornay PM (Methylphenidate Hydrochloride Extended-Release Capsules) on Adult ADHD Symptoms and Executive Function and Emotional Regulation Throughout the Day Into Early Evening
The goal of this study is to extend the efficacy evidence of sustained release methylphenidate compound (JornayPM) in adults with Attention-deficit/hyperactivity disorder (ADHD).
- Trial name
- NCT06577779
- Testing
- Methylphenidate Hydrochloride Extended Release Capsule
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- NYU Langone Health
Infertility, Female
Impact of Serum Progesterone in Modified Natural Cycles and Stimulated Cycles on Ongoing Pregnancy Rate
Prospective cohort unicentric study including infertile patients undergoing an embryo transfer in the context of natural or stimulated cycles and receiving luteal phase support with vaginal natural progesterone following the…
- Trial name
- CORPUS-LUTEUM (NCT04259996)
- Testing
- PROGESTERONE AND ESTRADIOL SERUM CONCENTRATION MEASUREMENT
- Where
- Spain
- Volunteers
- 488 people, healthy volunteers welcome
- Sponsor
- Instituto Valenciano de Infertilidad, IVI VALENCIA
Attention Deficit Disorder With Hyperactivity, Sensory Integration Disorder
Effect of ASI on Sensory, Motor, Cognitive, Behavioral Skills and Social Participation in Children With ADHD
Attention Deficit Hyperactivity Disorder (ADHD) is a very common neurodevelopmental disorder in childhood characterized by short attention span, impulsivity and hyperactivity.
- Conditions
- Attention Deficit Disorder With Hyperactivity, Sensory Integration Disorder, Motor Activity, Cognitive Deficit in Attention
- Trial name
- ASI-ADHD (NCT05718427)
- Testing
- Ayres Sensory Integration Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Pharmacokinetics of Mirabegron and Tolterodine, Healthy
Post-marketing Study to Evaluate the Effect of Mirabegron on the Plasma Concentration of Tolterodine
To assess the effect of multiple doses of mirabegron to postmenopausal adult female subjects on the pharmacokinetics (PK) of tolterodine and its metabolites. In addition, the safety of these products will be assessed.
- Trial name
- NCT01964183
- Testing
- tolterodine, mirabegron
- Where
- Japan
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Astellas Pharma Inc
Attention Deficit Hyperactivity Disorder, Disruptive Mood Dysregulation Disorder
Children With ADHD and Emotional Dysregulation
Studies have shown that children with Attention Deficit Hyperactivity Disorder (ADHD) and emotional dysregulation are characterized by high severity of ADHD, comorbid behavior disorders and increased risk of chronic difficulties.
- Trial name
- MOODY (NCT03944083)
- Testing
- Treatment as usual for ADHD
- Where
- Norway
- Volunteers
- 200 people
- Sponsor
- Oslo University Hospital
Attention Deficit, Hyperactivity Disorder
Brain Activity Associated With Inhibition of Action in Attention-deficit
Inhibitory control allows individuals to suppress unwanted actions and to resist irrelevant stimuli. It is thought to be a core deficit in Attention-deficit/hyperactivity disorder (ADHD).
- Trial name
- INHIB'MOV (NCT04768556)
- Testing
- EEG experimental sessions 1, EEG experimental sessions 2
- Where
- France
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University Hospital, Toulouse
Healthy
Differential Effects of Oral and Intranasal Oxytocin on Attention Control
The main aim of the present study is to investigate whether oxytocin (24IU) via different routes have divergent effects on attention control in a social-emotional saccade/antisaccade eye-tracking paradigm.
- Trial name
- NCT04815395
- Testing
- Oxytocin
- Where
- China
- Volunteers
- 151 people, healthy volunteers welcome
- Sponsor
- University of Electronic Science and Technology of China
High-flow Nasal Cannula, Exercise Capacity
Study on Optimal Oxygen Concentration During Pulmonary Rehabilitation
The purpose of this study is to compare the exercise capacity between high SpO2 (Minimum SpO2 94-96%) value during pulmonary rehabilitation and low SpO2 (Minimum SpO2 84-86%) value during pulmonary rehabilitation for the patients…
- Conditions
- High-flow Nasal Cannula, Exercise Capacity, Chronic Respiratory Failure, Optimal SpO2 Value
- Trial name
- NCT04481295
- Testing
- High-flow nasal cannula, Low SpO2
- Where
- Japan
- Volunteers
- 32 people
- Sponsor
- National Hospital Organization Minami Kyoto Hospital
Stress Disorders
Allostatic Load Assessment Using Hair Cortisol and Dehydroepiandrosterone Sulfate Concentration in Patients Affected by Periodontal Disease
This study was designed with a double-blind observation design on a population of patients with different periodontal conditions.
- Trial name
- NCT07443605
- Testing
- stressed periodontal patients
- Where
- Italy
- Volunteers
- 42 people
- Sponsor
- University of Trieste
Attention Deficit Hyperactivity Disorder (ADHD)
A Comparison of Group Cognitive Behavioural Therapy (CBT) and Structured Activity Group for Adults With Attention Deficit Hyperactivity Disorder (ADHD)
Many adults with attention deficit hyperactivity disorder (ADHD) experience difficulties with inattention, planning and impulsivity that impacts work and social life negatively also after treatment with medication.
- Trial name
- NCT06604845
- Testing
- Group cognitive behavioural therapy (CBT), Activity group
- Where
- Sweden
- Volunteers
- 226 people
- Sponsor
- Vastra Gotaland Region
Attention Deficit Disorder With Hyperactivity
Safety & Tolerability of MTS in Children Aged 6-12 Diagnosed With ADHD & Previously Treated With Extended-Release Methylphenidate Therapy
This study will assess the safety and tolerability of MTS while attempting to establish the appropriate starting dose for subjects previously on an existing long-acting methylphenidate product.
- Trial name
- NCT00151983
- Testing
- Methylphenidate Transdermal System
- Where
- 18 sites in United States
- Volunteers
- 175 people
- Sponsor
- Noven Therapeutics
Hip Arthroplasty, Hip Pain
Optimizing Local Anesthetic Concentration for Continuous Lumbar Plexus Nerve Blocks
This is a research study to determine if the concentration of local anesthetic through a catheter next to the nerves that go to the hip that is undergoing surgery, affects muscle strength and sense of touch experienced after…
- Trial name
- NCT00912873
- Testing
- 0.1% Ropivacaine, 0.4% Ropivacaine
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of California, San Diego
Colitis, Ulcerative, Crohn's Disease
Postmarketing Vedolizumab Milk-Only Lactation Study in Lactating Women With Active Ulcerative Colitis or Crohn's Disease
The purpose of this study is to assess the concentration of vedolizumab in breast milk of lactating women with active ulcerative colitis (UC) or Crohn's disease (CD) who are receiving vedolizumab therapeutically.
- Trial name
- NCT02559713
- Testing
- Vedolizumab
- Where
- 7 sites in United States
- Volunteers
- 11 people
- Sponsor
- Takeda
Other Conditions That May Be A Focus of Clinical Attention
Effect of Age on the Renal Clearance of Adefovir
Healthy African American subjects with normal hepatic and renal function will be administered 10mg adefovir dipivoxil in a fasting state.
- Trial name
- NCT00187746
- Testing
- Adefovir dipivoxil
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of California, San Francisco
ADHD
An Open-Label Study to Assess the Long-Term Safety of Solriamfetol in Children and Adolescents With ADHD
This study is a Phase 3, multi-center, open-label trial to evaluate the long-term safety of solriamfetol in children and adolescents with ADHD.
- Trial name
- NCT07773883
- Testing
- Solriamfetol
- Where
- 7 sites in United States
- Volunteers
- 300 people
- Sponsor
- Axsome Therapeutics, Inc.
Attention Deficit Hyperactivity Disorder
Effectiveness and Duration of Effect of Open Treatment in Attention Deficit Hyperactivity Disorder (ADHD) Patients Treated With Lisdexamfetamine Dimesylate(Vyvanse)
The purpose of this study is to examine the effectiveness and length of effect of Vyvanse on lessening Attention-Deficit/Hyperactivity Disorder symptoms in adults.
- Trial name
- NCT01070394
- Testing
- LDX Treatment
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- NYU Langone Health
Attention-deficit Hyperactivity
Pharmacist Management of Attention Deficit Hyperactivity Disorder Medication Refill Requests
This cluster randomized trial will compare pharmacist management of secure message requests for refills of attention deficit hyperactivity medications with primary care physician management regarding quality of care, timeliness…
- Trial name
- NCT06388694
- Testing
- Pharmacist Care, Primary Care Physician Care
- Where
- United States
- Volunteers
- 315 people
- Sponsor
- Kaiser Permanente
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