Clinical trials: Concentration
Myopia, Ear Acupressure Pellets
Effects of Auricular Point Pressing With Pellets in Children With Insufficient Hyperopia Reserve
This project aims to address the trend of early onset and high myopia among children in China by focusing on insufficient hyperopia reserve, a key early warning indicator for myopia.
- Conditions
- Myopia, Ear Acupressure Pellets, Hyperopia Reserve, Low-concentration Atropine Eye Drops
- Trial name
- NCT07475585
- Testing
- Ear acupoint pressure pellet intervention group, Atropine intervention group, Joint intervention Group
- Volunteers
- 380 people, healthy volunteers welcome
- Sponsor
- Fangbiao Tao
Chronic Pain, Major Depressive Disorder
The Internet Therapy for Depression Trial
The objective of this trial is to collect data on the feasibility, acceptability, and preliminary effectiveness of internet delivered Cognitive Beaviour Therapy (iCBT) and Acceptance and Commitment Therapy (iACT) interventions…
- Trial name
- INTEREST (NCT04009135)
- Testing
- internet delivered cognitive behavioural therapy (iCBT), online delivered acceptance and commitment therapy (iACT), Attention Control (AC)
- Where
- Canada
- Volunteers
- 12 people
- Sponsor
- Memorial University of Newfoundland
Attention Deficit Hyperactivity Disorder
Pharmacokinetic Study of DYANAVEL XR (Amphetamine) Extended-release Oral Suspension, in Children Aged 4 to 5 Years
The objective of this study was to evaluate the plasma amphetamine concentration/time profile of amphetamine extended release oral suspension in children aged 4 to 5 years with attention-deficit/hyperactivity disorder, following…
- Trial name
- NCT03610464
- Testing
- Amphetamine Extended Release Suspension [Dyanavel]
- Where
- United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Tris Pharma, Inc.
Attention Deficit Hyperactivity Disorder
Efficacy & Safety of KAPVAY™ Extended-Release in Children & Adolescents With Attention Deficit Hyperactivity Disorder
The purpose of this study is to determine the long-term efficacy and safety of KAPVAY™ (clonidine hydrochloride) extended-release in children and adolescents with Attention Deficit Hyperactivity Disorder (ADHD)
- Trial name
- NCT01439126
- Testing
- clonidine hydrochloride
- Volunteers
- 135 people
- Sponsor
- Concordia Pharmaceuticals Inc., Barbados
Attention Deficit Hyperactivity Disorder, Dyslexia
Implementation of Climb Up Program for Children With Attention Deficit Hyperactivity Disorder (ADHD) and Dyslexia in a School in India
A multimodal intervention was rolled out at a large public school in Najibabad, Uttar Pradesh (UP). The program identified elementary school children with ADHD and Dyslexia using standard screening of all children who had…
- Trial name
- ClimbUp (NCT01012778)
- Testing
- Climb Up ADHD and Dyslexia Program
- Where
- India
- Volunteers
- 76 people
- Sponsor
- Climb Up Kids
Cannabis, Memory
Cannabis Observations on Brain Waves, Retrieval, and Attention: Experiment 3
This study investigates the impact of ∆9-tetrahydrocannabinol (THC) and cannabidiol (CBD) on recognition memory in healthy, regular cannabis users.
- Conditions
- Cannabis, Memory, Electroencephalography
- Trial name
- COBRA 3 (NCT06669585)
- Testing
- Cannabis (smoked flower)
- Where
- United States
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- L. Cinnamon Bidwell
Otitis Media, Middle Ear Effusion
Middle Ear Disease Before Age 3, Treatment With Ear Tubes, and Literacy and Attentional Abilities at Ages 9 to 11
Middle-ear disease (infection and fluid) is the most common illness in young children after the common cold. Because hearing loss accompanies middle-ear disease, and because early life is a period of rapid development, concern…
- Trial name
- NCT00365092
- Testing
- Insertion of tympanostomy tubes
- Where
- United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Analgesia, Postoperative Pain
Volume vs Concentration: Quadratus Lumborum Blocks With High Volume/Low Concentration or Low Volume/ High Concentration in Nephrectomies
The quadratus lumborum has since 2016 become standard of care for abdominal and retroperitoneal surgeries at UPMC-Shadyside Hospital, replacing paravertebral blocks, and as part of a broader multimodal analgesia institutional…
- Conditions
- Analgesia, Postoperative Pain, Block
- Trial name
- NCT04077398
- Testing
- Ropivacaine 0.5% Injectable Solution
- Where
- United States
- Sponsor
- Bruce Ben-David
Subarachnoid Hemorrhage, Aneurysmal
Endothelin-1 and Methabolites Concentrations in Mycrodialysis and Cerebrospinal Fluid in Subarachnoid Hemorrhage Patients
Endothelin-1 (ET-1) seems to be involved in the pathogenesis of cerebral vasospasm after subarachnoid hemorrhage. However measurements of cerebrospinal fluid concentrations (CSF) of ET-1 are not sensitive enough to predict the…
- Trial name
- NCT01686763
- Volunteers
- 35 people
- Sponsor
- University of Turin, Italy
Attention
Lion's Mane Dosing on Attention and Mood
The primary purpose of the research is to evaluate in healthy adults the time course effects of varying dosages of Lion's mane mushroom on attention and mood.
- Trial name
- NCT07759687
- Testing
- Lion's Mane fruiting bodies extract
- Where
- United Kingdom
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Northumbria University
Infertility, Pregnancy Rate, Live Birth
Live Births With Low Oxygen Blastocyst Culture
The potentially damaging effect of free O2 radicals to cultured embryos may be reduced by adding scavengers to the culture media or by reducing the incubator O2 levels.
- Conditions
- Infertility, Pregnancy Rate, Live Birth, In Vitro Fertilization
- Trial name
- Oxygen (NCT00708487)
- Testing
- Embryo incubator oxygen concentration
- Where
- United States
- Volunteers
- 230 people
- Sponsor
- Texas Health Resources
ADHD - Attention Deficit Disorder With Hyperactivity, Bipolar Affective Disorder; Remission in
Psychophysiological Responses to Six Single-Session Self-Regulation Interventions in a Female Adult With ADHD and Stabilized Bipolar Disorder
This study aims to explore how six short, 15-minute self-regulation techniques affect the body and brain in a female adult with ADHD and stabilized bipolar disorder.
- Trial name
- NCT07437833
- Testing
- Moderate-Intensity Aerobic Exercise on Cycloergometer, Cyclic Sighing, Aromatherapy
- Where
- Poland
- Volunteers
- 1 people
- Sponsor
- Poznan University of Physical Education
Cholelithiasis
Endovenous Lidocaine and Serum Cytokines Concentration
Ineffective treatment of postoperative pain may cause organic damage and chronic pain. Nevertheless, opioids, the leading drugs used for this purpose, present side effects that sometimes restrict their usability.
- Trial name
- NCT02363699
- Testing
- Lidocaine, Saline solution
- Volunteers
- 44 people
- Sponsor
- Universidade Federal de Santa Maria
Erythematotelangiectatic Rosacea
Dose-Finding Study of CD07805/47 Topical Gel in Subjects With Erythematotelangiectatic Rosacea
This is a randomized, double-blind, parallel-group, vehicle-controlled, dose-finding study to investigate the pharmacodynamics and the safety of three dosages of CD07805/47 topical gel (0.07%, 0.18%, and 0.50%), after a single…
- Trial name
- NCT00989014
- Testing
- CD07805/47
- Where
- 5 sites in United States
- Volunteers
- 122 people
- Sponsor
- Galderma R&D
Pharmacokinetics, Anti-Bacterial Agents
Population Pharmacokinetics and Pharmacodynamics of Beta-lactams of Interest in Adult Patients From Intensive Care Units
Antibiotics are still most often administered on an empiric fashion, as defined for the general population with dosages only adapted based on weight and renal and/or hepatic functions.
- Conditions
- Pharmacokinetics, Anti-Bacterial Agents, Infection, Bacterial, Infections, Respiratory
- Trial name
- Pop-PK/PD (NCT03440216)
- Testing
- blood sampling, Tissue sampling (lung), Collection of fluid samples
- Where
- Belgium
- Volunteers
- 20 people
- Sponsor
- Université Catholique de Louvain
HIV - Human Immunodeficiency Virus, Cognitive Impairment
Cognitive Training for the Remediation of Functional Brain Health in HIV
Cognitive deficits in HIV reflect degraded brain network functioning that may be amenable to remediation through cognitive training.
- Trial name
- NCT02571504
- Testing
- Plasticity-based Adaptive Cognitive Remediation (PACR)
- Where
- Canada
- Volunteers
- 81 people
- Sponsor
- McGill University
Healthy, Cardiovascular Diseases
Effect of Phosphatidylcholine on Plasma Homocysteine in Healthy Volunteers
The purpose of this study is to determine whether supplementation with phosphatidylcholine lowers plasma homocysteine concentrations in healthy men.
- Trial name
- NCT00102232
- Testing
- supplementation with phosphatidylcholine
- Where
- 2 sites in Netherlands
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Wageningen Centre for Food Sciences
Healthy
Study to Determine the Sensitizing Potential of PEP005 Topical Gel in Healthy Volunteers Using a Repeat Insult Patch Test Design
To determine the sensitisation potential of PEP005 Topical Gel (0.01% concentration) on normal skin To evaluate skin irritation
- Trial name
- NCT00357916
- Testing
- PEP005 Topical Gel (0.01% concentration)
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Peplin
Attention Deficit Disorder With Hyperactivity
The Role of Adverse Environment Factors, Family Functioning and Parental Psychopathology in the Response to Treatment With Methylphenidate in Children and Adolescents With Attention Deficit/Hyperactivity Disorder
The purpose of this study is to investigate the association of adverse environmental factors, parental psychopathology, family functioning and genetic factors and the response to methylphenidate treatment in children and…
- Trial name
- NCT00773916
- Testing
- Methylphenidate
- Where
- Brazil
- Volunteers
- 130 people
- Sponsor
- Federal University of Rio Grande do Sul
Anesthesia
Prediction of Propofol Effect-Site Concentration Associated With Deep Anesthesia
The goal of this observational study is to explore the variability of the concentration at the effect site (Ce) of propofol to reach deep anesthesia (DA) during induction of general anesthesia in adults.
- Trial name
- PRESCOD-AI (NCT06346158)
- Testing
- Cognitive testing, electroencephalogram, High density electroencephalogram
- Where
- Canada
- Volunteers
- 110 people
- Sponsor
- Ciusss de L'Est de l'Île de Montréal
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