Clinical trials: Concentration
Heparin, Perioperative
Effects of Different Concentrations of Pressurized-heparin Flushing Fluid on Coagulation and Platelet Function Monitored by the Sonoclot Analyzer
Heparin diluent or normal saline is generally used as the arterial tube flushing in clinical practice, but there is no consensus on the choice of flushing fluid.
- Trial name
- NCT04355273
- Testing
- Heparin, normal saline
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Yangzhou University
Attention Deficit Hyperactivity Disorder
An Effectiveness and Safety Study Evaluating OROS Methylphenidate Hydrochloride (HCl), Ritalin (Methylphenidate HCl) and Placebo in Children With Attention Deficit Hyperactivity Disorder
The purpose of this study is to provide data on the effectiveness of the OROS Methylphenidate Hydrochloride (HCl) formulation compared to placebo and standard immediate-release Ritalin with respect to improving attention and…
- Trial name
- NCT00269776
- Testing
- OROS (methylphenidate HCl), Ritalin (methylphenidate)
- Sponsor
- Alza Corporation, DE, USA
Attention Deficit Hyperactivity Disorders, Neurodevelopmental Disorders
Good Night Project: Behavioural Sleep Interventions for Children With ADHD: A Randomised Controlled Trial
The study aims to implement and evaluate an RCT of behavioural sleep interventions for children aged 5-12 years with ADHD, and their primary caregivers, (women) in Saudi Arabia to address the following questions: 1.
- Conditions
- Attention Deficit Hyperactivity Disorders, Neurodevelopmental Disorders, Attention Deficit Disorder With Hyperactivity
- Trial name
- NCT02871674
- Testing
- Good Night Project
- Volunteers
- 60 people
- Sponsor
- University of Leeds
Stress, Psychological
Training Parents of Children With ADHD by Mindfulness-based Stress Reduction for Reducing Stress
The study aimed at comparing the effects of 8-week MBSR programme intervention group with usual care group in reducing parental stress and improving quality of life of parents of children with ADHD in Chinese culture.
- Trial name
- NCT06210113
- Testing
- Mindfulness-based Stress Reduction
- Where
- Hong Kong
- Volunteers
- 36 people
- Sponsor
- The Hong Kong Polytechnic University
Sars-CoV2
Concentration-effect Relationship of Enoxaparin for Thromboembolic Prevention
Patients with COVID-19 have special demographic characteristics including thromboembolic risk factors . The pharmacokinetics of enoxaparin administered subcutaneously in the intensive care unit patient are not described.
- Trial name
- COV-ENOX (NCT04520620)
- Testing
- Lovenox 40 MG in 0.4 mL Prefilled Syringe, Ultrasound of the lower limbs
- Where
- 4 sites in France
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
End-stage Renal Disease
Sodium Chloride and Protein-Bound Toxin Removal in Hemodiafiltration
An increase of the free fraction may allow a better removal of of protein-bound uremic toxins during dialysis. During predilution hemodiafiltration, the sodium chloride (NaCl) concentration will be increased in the infusion fluid…
- Trial name
- NCT01923961
- Testing
- HDF NaCl, Hemodialysis, Standard Predilution Hemodiafiltration
- Where
- Germany
- Volunteers
- 8 people
- Sponsor
- EXcorLab GmbH
Requiring Sedation by Sevoflurane in ICU, Adult Patients
Evaluation of Richmond Agitation Sedation Scale According to Alveolar Concentration of Sevoflurane During a Sedation With Sevoflurane in ICU Patients
Describe the Richmond Agitation Sedation Scale (RASS) values corresponding to the values of Minimum alveolar concentration of sevoflurane during sedation of patients in ICU
- Conditions
- Requiring Sedation by Sevoflurane in ICU, Adult Patients, Patients Covered by French Health Care System, Patients Who Have Given Their Consent
- Trial name
- SEVORASS (NCT02202720)
- Testing
- Sevoflurane
- Where
- France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Clermont-Ferrand
Gestational Diabetes
MTHFR Mutation and Concentration of B12,Folic Acid,Homocysteine and HS CRP in the Blood of Pregnant Women With GDM.
Research hypothesis: pregnant women with gestational diabetes have elevated serum CRP values and homocysteine compared to pregnant women with normal glucose metabolism Elevated CRP and homocysteine values are associated with…
- Trial name
- NCT04952324
- Testing
- Blood sampling and determination of MTHFR mutation,vitamin B12, folic acid, homocystein and HS CRP
- Where
- 2 sites in Bosnia and Herzegovina
- Volunteers
- 100 people
- Sponsor
- University of Mostar
Nicotine Dependence
Nicotine Replacement Therapy (NRT) and Bupropion Mechanisms of Effectiveness in Smokers
The purpose of this study is to better characterize differences in mood, attention, brain activation patterns underlying the beneficial effects of pharmacological treatments previously demonstrated to be help individuals…
- Trial name
- NCT01048944
- Testing
- Bupropion SR, Nicotine Patch
- Where
- United States
- Volunteers
- 197 people
- Sponsor
- Southern Illinois University Carbondale
Stroke, Brain Injuries
Efficacy of an Attentional Process Training Using Competitive Versus Non Competitive Strategies
Within a prospective, randomised, controlled study 60, selected patients with chronic (> 6 months) stroke or traumatic brain injury will be randomised to 30 1-hour sessions of competitive versus non-competitive attentional…
- Trial name
- NCT02220816
- Testing
- Competitive training, Non-Competitive Training
- Where
- Spain
- Volunteers
- 60 people
- Sponsor
- Hospitales Nisa
Sepsis, Infection
Meropenem and Piperacillin Plasma Concentrations During CRRT
This observational study reports meropenem and piperacillin plasma concentrations in patients treated with either antibiotic and simultaneous continuous renal replacement therapy (CRRT).
- Conditions
- Sepsis, Infection, Antibiotic, Renal Replacement Therapy
- Trial name
- ABC2 (NCT04203784)
- Testing
- Plasma concentration measurements
- Where
- Sweden
- Volunteers
- 135 people
- Sponsor
- Karolinska University Hospital
Pre-myopia
PROTECT-Study: Prospective Research on Optimizing Atropine Concentration Escalation for Children's Myopia Prevention
A prospective multicenter study design was adopted. Children aged 6-9 years with premyopia who met the criteria were screened and administered after completion of baseline assessment. Phase I: 0-24 weeks (0-6M).
- Trial name
- PROTECT (NCT07449247)
- Testing
- 0.01% Atropine
- Volunteers
- 233 people, healthy volunteers welcome
- Sponsor
- Tianjin Medical University Eye Hospital
Attention Deficit Hyperactivity Disorder
A Study of Atomoxetine for Attention Deficit and Hyperactive/Impulsive Behaviour Problems in Children With ASD
The primary purpose of this study is to evaluate the tolerability and effectiveness of atomoxetine in the treatment of attention problems, hyperactivity, and impulsivity in children with ASD, and secondarily, to evaluate the…
- Trial name
- NCT00485849
- Testing
- Atomoxetine Hydrochloride
- Where
- Netherlands
- Volunteers
- 12 people
- Sponsor
- Eli Lilly and Company
Exercise Intervention
Exercise Intervention on Conflict Monitoring in Children With Attention-deficit Hyperactivity Disorder
The study mainly investigates the effect of high-intensity interval training on conflict monitoring in children with ADHD by using event-related potential and sLORETA techniques.
- Trial name
- ADHD (NCT04112758)
- Testing
- High-intensity interval training
- Where
- Taiwan
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- National Taiwan Normal University
Autism, Challenging Behavior
Testing a Measurement Feedback App to Improve Data Quality, Supervision & Outcomes in Behavioral Health
The goal of this clinical trial is to test whether a smartphone-based data collection and feedback application ("Footsteps") improves the quality of behavioral data collected by one-to-one aides and leads to better youth mental…
- Conditions
- Autism, Challenging Behavior, ADHD, Oppositional Defiant Disorder
- Trial name
- Footsteps (NCT07042347)
- Testing
- Behavioral economics strategies, Electronic platform
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Feeding Difficulties, Aspiration
The Use of High Bile-binding Foods to Reduce Upper Gastrointestinal Bile Acid Concentrations (Aim 1)
We will perform an acute physiology study comparing three different diets-an amino acid-based formula, a low bile acid-binding blenderized diet, or a high bile acid-binding blenderized diet administered through gastrostomy tube.
- Conditions
- Feeding Difficulties, Aspiration, Gastrostomy
- Trial name
- NCT07303738
- Testing
- amino acid based formula (e.g. Elecare Jr), low bile acid binding blenderized diet (e.g. Kate Farms), high bile acid binding blenderized diet
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Boston Children's Hospital
Attention Deficit Hyperactivity Disorder, Autism Spectrum Disorder
Neural Mechanisms of Sensory Processing Anomalies
To assess sensory processing anomalies in neurotypical children, children with autism spectrum disorder, and attention-deficit hyperactivity disorder, particularly within the vibrotactile and auditory sensory modalities.
- Conditions
- Attention Deficit Hyperactivity Disorder, Autism Spectrum Disorder, Sensory Processing Disorder
- Trial name
- NCT06234033
- Testing
- Discrimination Acuity test, Transiently Evoked Otoacoustic Emission, Questionnaires
- Where
- Denmark
- Volunteers
- 75 people
- Sponsor
- Aalborg University
Color, Bleaching Sensitivity
Whitening Efficacy and Tooth Sensitivity of Different Concentrations of Hydrogen Peroxide Photoactivated With Violet or Blue LEDs
This is a randomized, controlled, double-blind and repeated-measures clinical trial evaluated the photoactivation of hydrogen peroxide gels in different concentrations with blue or violet LED in terms of whitening efficacy and…
- Trial name
- NCT06165458
- Testing
- 6% hydrogen peroxide gel + violet LED, 6% hydrogen peroxide gel + blue LED, 35% hydrogen peroxide gel + violet LED
- Where
- Brazil
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Universidade Federal do Para
COVID-19, Chronic Heart Failure
Intermittent Hypoxic-hyperoxic Training in Patients With Cardiovascular Pathology After COVID-19 Infection.
Aim of this prospective, interventional, single-center, randomized study is to evaluate the efficacy and safety of intermittent hypoxic-hyperoxic training (IHHT) as a rehabilitation method in patients with cardiovascular…
- Conditions
- COVID-19, Chronic Heart Failure, Hypertension, Arrhythmia
- Trial name
- NCT05379608
- Testing
- Intermittent hypoxic-hyperoxic training, Intermittent hypoxic-hyperoxic training/control
- Where
- Russia
- Volunteers
- 43 people
- Sponsor
- I.M. Sechenov First Moscow State Medical University
Diverticulosis, Colonic, Rectal Neoplasms
Concentration of Ertapenem in Colorectal Tissue
The purpose of this study is to determine the tissue kinetics of ertapenem in colonic tissue from three hours up to six hours (25% of dosing interval) after administration of ertapenem.
- Conditions
- Diverticulosis, Colonic, Rectal Neoplasms, Colonic Neoplasms
- Trial name
- NCT00535652
- Testing
- Ertapenem
- Where
- Germany
- Volunteers
- 23 people
- Sponsor
- University of Ulm
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