Clinical trials: Concussion (Diagnosis)
Mild Traumatic Brain Injury, Chronic Pain
Neuromodulation and Yoga for Mild Traumatic Brain Injury and Chronic Pain
The objectives of this VA SPiRE application are to develop a combined neuromodulation and yoga (iTBS+yoga) intervention for Veterans with mild traumatic brain injury (mTBI) and chronic pain, assess the intervention's feasibility…
- Trial name
- NCT04517604
- Testing
- Magventure MagProx100 with MagOption
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- VA Office of Research and Development
Mild Traumatic Brain Injury
Regulation of Emotion, Sleep Extension, and mTBI
Concussions are incredibly common, and often result in severe and long lasting symptoms, including, but not limited to, sleep deprivation and emotion dysregulation.
- Trial name
- RESET (NCT06883006)
- Testing
- Sleep Extension
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Merrimack College
Craniocerebral Trauma, Pediatrics
Study Assessing Evaluation of the Interest of Serum S100B Protein Determination in the Management of Pediatric Mild Traumatic Brain Injury
Mild traumatic brain injury (mTBI) is a very common reason for presentation to pediatric emergency departments. So as not to overlook the risk of complications, which occur at a rate of 0-7%, measures such as cranial computed…
- Trial name
- PROS100B (NCT02819778)
- Testing
- usual care, S100B
- Where
- 11 sites in France
- Volunteers
- 2,209 people
- Sponsor
- University Hospital, Clermont-Ferrand
Traumatic Brain Injury
Evaluation of Mild TBI in Collegiate Athletes
The purpose of this study is to evaluate blood-based biomarkers before and after sports-induced concussion using neuroimaging and head impact sensor technology.
- Trial name
- AWARE (NCT02189525)
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Banyan Biomarkers, Inc
Mild Traumatic Brain Injury
Graded Exposure Therapy for Fear Avoidance Behaviour After Concussion
Concussions are very common. Although many people recover well from concussion, some will have persistent symptoms and difficulties with daily activities.
- Trial name
- GET-FAB (NCT05365776)
- Testing
- Graded Exposure Therapy, Prescribed aerobic exercise, Enhanced usual care
- Where
- 7 sites in Canada
- Volunteers
- 220 people
- Sponsor
- University of British Columbia
Concussion, Brain, Traumatic Brain Injury
Ghrelin (OXE--103) for Acute Concussion Management
Concussions are the leading form of mild traumatic brain injury. Management of concussions and mild traumatic brain injury is a high priority medical focus, social concern, and research topic.
- Trial name
- NCT04558346
- Testing
- Ghrelin (OXE-103)
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- Michael Rippee
Concussion, Post-concussion Syndrome
Aerobic Training for Management of Post-Concussion Syndrome in Adolescents
Sports-related concussions are common in adolescent-athletes. Prolonged recovery after concussion or post-concussion syndrome (PCS) is a public health problem.
- Conditions
- Concussion, Post-concussion Syndrome, Sports Injury
- Trial name
- NCT02035579
- Testing
- Aerobic Training Intervention, Stretching Intervention
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Concussion, Mild
Use of CBT-I in Individuals With a Concussion
Sleep disturbances have been shown to contribute to poorer recovery from a concussion. Furthermore, sleep disturbances have been associated with more frequent and severe post-concussion symptoms including headache, vertigo…
- Trial name
- NCT04885205
- Testing
- cognitive behavioral therapy for insomnia (CBT-I)
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Kansas Medical Center
Brain Concussion
Effects of Early Vestibular Rehabilitation in Patients With Dizziness and Balance Disorders After Sport Concussion
This study examines the effect of early vestibular rehabilitation on reducing physical post-concussion symptoms (e.g. dizziness, balance problems) and improving the timeline to achieve medical clearance to return to activities…
- Trial name
- NCT02945605
- Testing
- Early Vestibular Rehabilitation, Standard of Care
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- University of Michigan
Dementia, Mild Cognitive Impairment
Video Games to Track Cognitive Health
The purpose of this study is to assess cognitive function using a rapid, portable, computerized neurocognitive testing device in a wide variety of clinical settings.
- Conditions
- Dementia, Mild Cognitive Impairment, Cognitive Impairment, Cognitive Decline
- Trial name
- NCT03608722
- Testing
- SLUMS, MMSE, MoCA
- Volunteers
- 2,500 people, healthy volunteers welcome
- Sponsor
- BrainCheck, Inc.
Concussion
Does Oral Micronized Progesterone Shorten Time of Symptoms From Concussion
Concussions are a common injury among athletes in the United States. The annual incidence of sports and recreational related traumatic brain injuries in the United States is 1.6 to 3.8 million, and the likelihood of an athlete in…
- Trial name
- NCT01809639
- Testing
- Progesterone
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Wake Forest University Health Sciences
Mild Traumatic Brain Injury, Concussion, Chronic Dizziness
Repetitive Transcranial Magnetic Stimulation Paired with Augmented Reality to Alter Concussion Symptoms
This study aims to determine whether the delivery of brain stimulation paired with a balance training task can improve symptoms of dizziness for individuals experiencing these symptoms due to concussion.
- Conditions
- Mild Traumatic Brain Injury, Concussion, Chronic Dizziness, Vestibular Problem
- Trial name
- NCT06735157
- Testing
- Repetitive transcranial magnetic stimulation, Augmented reality vestibular rehabilitation therapy
- Where
- 2 sites in Canada
- Volunteers
- 40 people
- Sponsor
- McMaster University
Concussion, Brain, Traumatic Injury
Sport Concussion Performance-Based Prevention Program
Sport-related concussions and traumatic lower body injuries (e.g., anterior cruciate ligament (ACL) tears) occur frequently in high-speed and contact/collision sports contributing to significant time loss from…
- Trial name
- NCT04992130
- Testing
- Pre-season supplementary neurologic training program
- Where
- Canada
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Post-Concussion Syndrome
Craniosacral Therapy for Concussion Symptoms
This study investigated the utilization of CranioSacral Therapy (CST) in patients with Post-Concussion Syndrome (PCS) and capture patient-reported perceptions of their lived experiences of treatment effect upon their symptoms.
- Trial name
- NCT04820192
- Testing
- Craniosacral Therapy
- Where
- United States
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Special Therapies, Inc.
Traumatic Brain Injury (TBI) Patients
Effect of Fixation Training With Colored Light Targets on Traumatic Brain Injury-Associated Photophobia
Many people develop intolerance to light after a head injury, leading to ambient light levels causing discomfort. We do not fully understand why this occurs and how it should be treated.
- Trial name
- NCT07606300
- Testing
- Fixation training using different colored fixation targets
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Ohio State University
Traumatic Brain Injury, Sports Concussion
A Evaluation Of Biomarkers Associated With Sports Induced Concussions In College Student Athletes
The purpose of this study is to study the biomarkers in subjects before and after sports-induced traumatic brain injury. The assay will be studied in a sample population of subjects over the age of 18 participating in college…
- Conditions
- Traumatic Brain Injury, Sports Concussion, Sports Injury
- Trial name
- GATOR (NCT01472042)
- Testing
- Banyan Biomarkers
- Where
- United States
- Volunteers
- 265 people, healthy volunteers welcome
- Sponsor
- Banyan Biomarkers, Inc
Concussion, Mild, Photophobia
Use of Tinted Contact Lenses for Concussion-Related Light Sensitivity
The purpose of this study is to gather pilot data on the effectiveness of daily disposable tinted contact lenses in reducing photophobia (light sensitivity) following a concussion, with the goal of facilitating the return to work…
- Conditions
- Concussion, Mild, Photophobia, Contact Lens
- Trial name
- NCT07223086
- Testing
- Narrow band (tinted) contact lenses, broad band (clear) contact lenses
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Alabama at Birmingham
Mild Traumatic Brain Injury
The Use of the VOMS Tool With Military Personnel to Track mTBI Recovery and RTD Status
The purpose of the proposed project is to determine if the VOMS is an effective screening tool to identify and track recovery of vestibular and ocular motor impairment and symptoms following mTBI, that corpsman-level medical…
- Trial name
- NCT02634944
- Testing
- Vestibular Ocular Motor Screening Tool (VOMS)
- Where
- United States
- Volunteers
- 452 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Concussion
Evaluation of an EEG Based Concussion System
This study will evaluate the accuracy of a new concussion system at detecting concussions. The investigators will be evaluating the degree to which data collected with the device agrees with a physician's determination of a…
- Trial name
- NCT03710109
- Testing
- EEG
- Where
- 2 sites in United States
- Volunteers
- 150 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Concussion, Mild
Impact of Instability Training on Vestibular Dysfunction in Postconcussion Combat Athletes
We are conducting RCT study on concussion on combat sports athlete and there is high incidence of on concussion in this sports and we will find the association between concussion and vestibular impairment and then we will apply…
- Trial name
- NCT07729761
- Testing
- Traditional Physical therapy, Instability training
- Where
- Pakistan
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Riphah International University