Clinical trials: Condition
Colorectal Cancer, Colon Cancer
BESPOKE Study of ctDNA Guided Therapy in Colorectal Cancer
The BESPOKE CRC study will prospectively enroll patients who have undergone surgery for stage I to IV colorectal cancer (CRC) and who have residual formalin-fixed paraffin-embedded (FFPE) tissue available will provide FFPE and…
- Trial name
- NCT04264702
- Where
- United States
- Volunteers
- 1,788 people
- Sponsor
- Natera, Inc.
Pain, Muscle Rigidity
Investigation on a Topical Cosmetic Pain Lotion (Egyfil) for Stiffness and Pain Relief
The application of a novel topical formulation for the treatment of muscular pain and stiffness (Egyfil), containing hyaluronic acid, SH-Polypeptide-6 and SH-Oligopeptide-1, is investigated to evaluate efficacy and safety in 26…
- Trial name
- NCT05711953
- Testing
- Egyfil Pain Lotion
- Where
- Italy
- Volunteers
- 26 people
- Sponsor
- Contrad Swiss SA
Infective Disorder
Clinical Trial of Comparing DA-2902 and DA-2902-R in Healthy Adult Subjects
This study is to compare pharmacokinetics and safety profiles of DA-2902 and DA-2902-R in healthy adult subjects
- Trial name
- NCT07239453
- Testing
- DA-2902, DA-2902-R
- Where
- South Korea
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Dong-A ST Co., Ltd.
Osteoarthritic Knee Pain
Freedom-1 Study for Chronic Knee Pain
To demonstrate the potential benefits and risk of active sub-threshold stimulation in the treatment of chronic knee pain as compared to subjects that did not have active stimulation.
- Trial name
- NCT03877653
- Testing
- Wireless neuromodulation
- Where
- 13 sites in United States
- Volunteers
- 100 people
- Sponsor
- Curonix LLC
Asthma
A Study to Assess the Systemic Exposure of FLIXOTIDE™ (Fluticasone Propionate) and SERETIDE™ (Fluticasone Propionate and Salmeterol) Given With VENTOLIN™ Mini-Spacer Compared to the Aerochamber Plus Spacer
The VENTOLIN Mini-Spacer is being developed in order to support patients in the Emerging Markets and Asia Pacific regions who do not have access to affordable spacers.
- Trial name
- NCT02045953
- Testing
- VENTOLIN Mini-Spacer, Aerochamber Plus spacer
- Where
- United Kingdom
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Chronic Hepatitis B
A Clinical Study of HT-101 and HT-102 in Patients With Chronic Hepatitis B Virus Infection
This study is A multicenter, randomized, double-blind, placebo-controlled phase 2 clinical study to evaluate the efficacy and safety of HT-101 injection combined with HT-102 injection in patients with chronic hepatitis B.
- Trial name
- NCT07245953
- Testing
- HT-101, HT-102
- Where
- 12 sites in China
- Volunteers
- 60 people
- Sponsor
- Suzhou HepaThera Biotech Co., Ltd.
Allergic Rhinitis
Onset of Effect of Mometasone Nasal Spray in Induced Allergic Rhinitis (Study P03431)
This was a single-dose study to determine the time it takes for mometasone furoate nasal spray to go in effect, after a single dose of 2 sprays per nostril.
- Trial name
- NCT00783237
- Testing
- Mometasone
- Volunteers
- 340 people
- Sponsor
- Organon and Co
Colon Cancer
Study to Assess the Tolerability, Safety and Efficacy of an Adapted Gut Cleansing Solution in Routine Colon Cleansing Prior to Colonoscopies
It is particularly important that thorough gut cleansing is achieved prior to the colonoscopy for the procedure to be successful.
- Trial name
- NCT01251237
- Testing
- NRL0706
- Where
- Germany
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Norgine
Healthy Volunteers
Multiple Dose Pharmacokinetics of Canagliflozin/Metformin 150/1,000 mg Fixed Dose Combination
The purpose of this study is to evaluate the multiple dose pharmacokinetics of 2 Canagliflozin/extended release Metformin (CANA/MET XR) fixed dose combination tablets (150 mg/1,000 mg each) following once-daily oral dosing in…
- Trial name
- NCT02039245
- Testing
- CANA/MET XR FDC
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Janssen Research & Development, LLC
Lupus Nephritis, Systemic Lupus Erythematosus
US Zamto-cel Autoimmune Diseases
AID is a phase I multi-cohort study to assess the safety and tolerability of zamtocabtagene autoleucel (zamto-cel) in patients with refractory autoimmune diseases (SLE-Non renal, SLE-LN, SSc/dcSSc) after receiving standard…
- Conditions
- Lupus Nephritis, Systemic Lupus Erythematosus, Systemic Sclerosis (SSc), Diffuse Cutaneous Systemic Sclerosis
- Trial name
- NCT06708845
- Testing
- zamtocabtagene autoleucel, Cyclophosphamide, Fludarabine
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Miltenyi Biomedicine GmbH
Gastroesophageal Reflux, Gastric Ulcer
Safety of Rabeprazole in Patients Under Multiple Treatments
The purpose of this study is to evaluate the safety of rabeprazole 20mg/day in polymedicated patients and to examine the necessity of adjusted dosage in both therapies (rabeprazole and concomitant drug).
- Trial name
- NCT00511745
- Testing
- Rabeprazol
- Volunteers
- 2,157 people
- Sponsor
- Janssen-Cilag, S.A.
Rheumatoid Arthritis
VELVET, a Dose Range Finding Trial of Veltuzumab in Subjects With Moderate to Severe Rheumatoid Arthritis
This is a multi-national, multi-centre, placebo-controlled, double-blind, randomized, 4-arm parallel group trial, comparing three different dose levels (80 mg, 160 mg and 320 mg) of veltuzumab to placebo, administered weekly…
- Trial name
- VELVET (NCT01390545)
- Testing
- Veltuzumab
- Where
- 63 sites in United States, Argentina and 9 more
- Volunteers
- 300 people
- Sponsor
- Takeda
Dysmenorrhea
Assessment of a Vaginal Ring With Meloxicam in the Treatment of Dysmenorrhea
The investigators propose that the sustained administration of a vaginal ring would have a better response with respect to pain and a better safety profile than the oral administration of a non-steroidal anti-inflammatory drug.
- Trial name
- NCT02255045
- Testing
- Meloxicam, Diclofenac Potassium
- Where
- Chile
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Laboratorios Andromaco S.A.
Inflammatory Bowel Disease (IBD), Anemia
Study of DISC-0974-201 in Participants With IBD and Anemia
This is a Phase 2, multicenter, randomized, double-blind placebo-controlled study of DISC-0974 to evaluate safety, tolerability, and efficacy in participants with IBD and anemia of inflammation.
- Conditions
- Inflammatory Bowel Disease (IBD), Anemia, Inflammatory Bowel Disease (IBD); Anemia
- Trial name
- NCT07368972
- Testing
- DISC-0974
- Where
- 15 sites in United States
- Volunteers
- 21 people
- Sponsor
- Disc Medicine, Inc
Carcinoma, Renal Cell
Phase I Study of Pazopanib Alone and In Combination With Lapatinib in Japanese Patients With Solid Tumors
This is a two part phase I study in Japanese patients that will determine the safety, tolerability and pharmacokinetics of pazopanib monotherapy and of pazopanib in combination with lapatinib.
- Trial name
- NCT00516672
- Testing
- pazopanib, Lapatinib
- Where
- 2 sites in Japan
- Volunteers
- 30 people
- Sponsor
- GlaxoSmithKline
Erythropoietic Protoporphyria
Study of Bitopertin to Evaluate the Safety, Tolerability, Efficacy, and PPIX Concentrations in Participants With EPP
This is a Phase 2, multi-center, double-blind, placebo-controlled, parallel group study of bitopertin to evaluate the safety, tolerability, efficacy, and PPIX concentration change in participants with EPP.
- Trial name
- NCT05308472
- Testing
- DISC-1459
- Where
- 9 sites in United States
- Volunteers
- 75 people
- Sponsor
- Disc Medicine, Inc
Type 2 Diabetes Mellitus
An Investigational Drug Study in Adults With Type 2 Diabetes on Basal Insulin (MK-0941-006)
A study to assess safety, pharmacokinetics (PK), and pharmacodynamics (PD) of MK-0941 in Type 2 diabetics being treated with basal insulin.
- Trial name
- NCT00511472
- Testing
- MK-0941, LANTUS insulin
- Volunteers
- 70 people
- Sponsor
- Merck Sharp & Dohme LLC
PTSD
OM and Trauma Study
The primary purpose of this study is to use an unblinded, uncontrolled, 1-month interventional single group pilot study, to assess the possibility of Orgasmic Meditation practice being used as a possible intervention for PTSD.
- Trial name
- OMTP (NCT05577377)
- Testing
- Orgasmic Meditation
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Institute of OM Foundation
Androgenetic Alopecia
A Novel Approach to Treating Androgenetic Alopecia in Females With Low Level Laser Therapy
This study will acquire data on hair growth of the head that is the result of treatment with a non-heat generating, laser product.
- Trial name
- NCT01967277
- Testing
- Handi-Dome Laser, Incandescent red light source.
- Where
- 2 sites in United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Capillus, LLC
Pneumococcal Infectious Disease
Clinical Trial of PCV24 in Adults
A Phase I clinical trial of 24-valent pneumococcal conjugate vaccine (PCV24) developed by Sinovac Life Science Co., Ltd will be conducted in adults aged 18 years and older.
- Trial name
- NCT06474377
- Testing
- Sinovac PCV24 formulation 1, Sinovac PCV24 formulation 2, Pneumovax®
- Where
- China
- Volunteers
- 170 people, healthy volunteers welcome
- Sponsor
- Sinovac Life Sciences Co., Ltd.
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