Clinical trials: Condition
Prostate Cancer
Danish Prostate Cancer Consortium Study-1
The purpose of the study is to investigate if a new promising microRNA-based urine biomarker test for prostate cancer, called uCaP, is better than the current standard test (PSA) to identify men who would benefit from an MRI scan…
- Trial name
- DPCC-1 (NCT05767307)
- Where
- 3 sites in Denmark
- Volunteers
- 2,500 people
- Sponsor
- Aarhus University Hospital
Rheumatoid Arthritis
A Study of RoActemra/Actemra (Tocilizumab) in Combination With Methotrexate in Patients With Active Rheumatoid Arthritis Who Have an Inadequate Response to Disease-Modifying Antirheumatic Drugs (DMARDs) (ALABASTER)
This open-label, single arm study will assess the safety and efficacy of RoActem ra/Actemra (tocilizumab) in combination with methotrexate in patients with activ e moderate to severe rheumatoid arthritis who have an inadequate…
- Trial name
- NCT01235507
- Testing
- methotrexate, tocilizumab [RoActemra/Actemra]
- Where
- 3 sites in Bosnia and Herzegovina
- Volunteers
- 71 people
- Sponsor
- Hoffmann-La Roche
Bipolar Disorder
Extension Study of Asenapine [P06107 (NCT01244815)] for Pediatric Bipolar Disorder (P05898)
This study will investigate the safety and tolerability of a flexible dosing regimen of asenapine for the long-term treatment of manic or mixed episodes associated with bipolar disorder I in children and adolescents who completed…
- Trial name
- ADDRESS-98 (NCT01349907)
- Testing
- Asenapine, Rescue medication
- Volunteers
- 322 people
- Sponsor
- Organon and Co
Prostate Cancer, Prostate Adenocarcinoma
A Study of Enzalutamide Plus the Glucocorticoid Receptor Antagonist Relacorilant Versus Placebo for Patients With High-risk Localized Prostate Cancer
Researchers conducting this study hope to learn about the safety and effectiveness of combining two study drugs, relacorilant and enzalutamide, plus androgen deprivation therapy (ADT), also known as hormone therapy.
- Trial name
- NCT05726292
- Testing
- Relacorilant, Enzalutamide, Androgen Deprivation Therapy
- Where
- 4 sites in United States
- Volunteers
- 90 people
- Sponsor
- University of Chicago
Thromboembolic Disorders
A Trial to Learn How a New Liquid Form of Rivaroxaban Behaves and How Safe it is Compared to the Current Tablet Form of Rivaroxaban in Healthy Male Participants
Researchers were looking for another way to treat people with a blood clot in their veins. Before a treatment can be approved for people to take, researchers do clinical trials to better understand its safety and how it behaves.
- Trial name
- NCT04720092
- Testing
- Rivaroxaban (Xarelto, BAY59-7939)
- Where
- Germany
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Bayer
COVID-19, Olfactory Disorder
Efficacy of Gabapentin for Post-Covid-19 Olfactory Dysfunction
This study will investigate the efficacy of oral gabapentin in olfactory improvement following Covid-19- associated olfactory dysfunction. This is a randomized, double-blinded, placebo-controlled trial.
- Conditions
- COVID-19, Olfactory Disorder, Anosmia, Hyposmia
- Trial name
- GRACE (NCT05184192)
- Testing
- Gabapentin gelatin capsules 300mg
- Where
- United States
- Volunteers
- 68 people
- Sponsor
- Washington University School of Medicine
Tobacco Dependence
Single-dose Nicotine Pharmacokinetics With Three Oral Nicotine Replacement Products. A Study in Healthy Smokers.
Single-dose nicotine pharmacokinetics with three oral nicotine replacement products.
- Trial name
- NCT01234792
- Testing
- 6 mg Experimental nicotine gum, 4 mg Nicotine Gum/, 2 mg Nicotine Gum
- Where
- Sweden
- Volunteers
- 24 people
- Sponsor
- McNeil AB
Breast Cancer
Toxicity Outcomes of Simultaneous Integrated Boost in Adjuvant Breast Radiotherapy Acronym
This prospective study systematically evaluates toxicity outcomes in breast cancer patients treated with adjuvant radiotherapy using the simultaneous integrated boost (SIB) technique after breast-conserving surgery.
- Trial name
- SIB (NCT07407192)
- Testing
- Adjuvant Breast Radiotherapy With Simultaneous Integrated Boost (SIB)
- Where
- Slovenia
- Volunteers
- 93 people
- Sponsor
- Institute of Oncology Ljubljana
Ventricular Premature Complexes
Relativity Study Between Idiopathic Ventricular Arrhythmia and Sex Hormone Levels in Different Stages of Menstrual Cycle
The purpose of this study is to determine whether the occurrence of idiopathic right ventricular outflow tract(RVOT) arrhythmia is relative to sex hormone levels in different stages of female menstrual cycle
- Trial name
- NCT00606736
- Where
- China
- Volunteers
- healthy volunteers welcome
- Sponsor
- Harbin Medical University
Atrial Fibrillation
a Novel Individualized Substrate Modification Approach for the Treatment of Long-standing Persistent Atrial Fibrillation
The purpose of this study is to compare effectiveness of two substrate modification approaches in long-standing persistent atrial fibrillation patients, and hypothesized that a substrate-based, individualized substrate…
- Trial name
- NCT02477592
- Testing
- individualized substrate modification, stepwise ablation
- Where
- China
- Volunteers
- 220 people
- Sponsor
- RenJi Hospital
SIAD - Syndrome of Inappropriate Antidiuresis, Hyponatremia
Effects of Intravenous [Pyr1]Apelin-13 on Healthy Volunteers With Artificially Induced SIAD
Hyponatremia is a common electrolyte imbalance which often results from hormonal disregulation. The study aims to investigate whether the apelin hormone, which plays a role in regulating salt and water balance in the body, can be…
- Trial name
- ESCAPE (NCT06277336)
- Testing
- Apelin Low Dose, Apelin High Dose, Selected Apelin Dose
- Where
- Switzerland
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Bronchiectasis, Lung Disease
Evaluation of the Effect of AZD5069 in Patients With Bronchiectasis
The purpose of this study is to investigate the effect of AZD5069 in patients with bronchiectasis.
- Conditions
- Bronchiectasis, Lung Disease, Respiratory Diseases
- Trial name
- STRATUS (NCT01255592)
- Testing
- AZD5069
- Where
- 15 sites in Czechia, Poland and 1 more
- Volunteers
- 83 people
- Sponsor
- AstraZeneca
Cerebral Palsy
Evaluation of Functional Status and Mental Functions of Adult Cerebral Palsy Patients
In adult cerebral palsy patients , a questionnaire study will be conducted to determine the functional level and to determine the effect on quality of life.
- Trial name
- NCT03848936
- Testing
- Survey
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Istanbul Medeniyet University
Hepatitis B
Efficacy Study of Combined Hepatitis A and Hepatitis B Vaccine to Protect Against Hepatitis B in Hemodialysis Patients
Does vaccinating hemodialysis patients with Twinrix® (combination vaccine against hepatitis A and hepatitis B) result in a difference in hepatitis B antibody response in comparison to the monovalent hepatitis B vaccine? Hepatitis…
- Trial name
- NCT00186836
- Testing
- Engerix-B and Twinrix
- Where
- Canada
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- St. Joseph's Health Care London
Chronic Coccydynia, Alexithymia
Evaluation of Alexithymia and Its Relationship With Clinical Parameters in Patients With Chronic Coccydynia
This study aims to investigate the prevalence and levels of alexithymia in patients diagnosed with chronic coccydynia (tailbone pain lasting for 3 months or longer) and to explore its relationship with various clinical and…
- Trial name
- NCT07696260
- Where
- Turkey (Türkiye)
- Volunteers
- 15 people
- Sponsor
- Marmara University
Type 2 Diabetes, ObesityType 2 Diabetes Mellitus
The Impact of Laser Acupuncture on Type 2 Diabetes
Laser Acupuncture for Type 2 Diabetes and Body Shape The goal of this clinical trial is to learn if laser acupuncture can help improve body shape and overall health in women with Type 2 Diabetes (T2D).
- Trial name
- LA/ABSI (NCT07661160)
- Testing
- Laser Acupuncture
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Cairo University
Behavior Disturbance, Muscle Hypotonia
Effect of Massage Therapy in a Multisensory Environment for Intellectual Disabilities
The aim of this study is to evaluate the effectiveness of multisensory environment (MSE) and/or massage therapy (MT) in residents with severe and profound intellectual disabilities (ID) who received massage therapy in MSE…
- Trial name
- MT-MSE (NCT02120820)
- Testing
- Multisensory environment (MSE), Massage therapy (MT), Control group
- Where
- Hong Kong
- Volunteers
- 240 people
- Sponsor
- The Hong Kong Polytechnic University
Degenerative Disc Disease, Back Pain Lower Back Chronic
The SPINUS II Study: Spinal Fusion for Multilevel SPECT/CT Positive Lumbar Degeneration
The aim of the present study is to find out whether fusion of multilevel SPECT/CT positive lumbar degeneration leads to a significant improvement of pain and disability.
- Conditions
- Degenerative Disc Disease, Back Pain Lower Back Chronic, Facet Joint Arthropathy, Facet Syndrome of Lumbar Spine
- Trial name
- NCT04893720
- Testing
- Lumbar fusion
- Where
- 2 sites in Czechia
- Volunteers
- 30 people
- Sponsor
- Military University Hospital, Prague
Alzheimer Disease, Cognitive Dysfunction
A Study of JNJ-63733657 in Participants With Early Alzheimer's Disease
The primary purpose of this study is to evaluate the effect of JNJ-63733657 versus placebo on clinical decline as measured by the Integrated Alzheimer's Disease Rating Scale (iADRS), a composite of cognition and function.
- Conditions
- Alzheimer Disease, Cognitive Dysfunction, Dementia
- Trial name
- Autonomy (NCT04619420)
- Testing
- JNJ-63733657
- Where
- 122 sites in United States, Australia and 8 more
- Volunteers
- 523 people
- Sponsor
- Janssen Research & Development, LLC
Hemorrhage
Safety, Tolerability, PK and PD of BI 655075 and Establishment of BI 655075 Dose(s) Effective to Reverse Prolongation of Blood Coagulation Time by Dabigatran
To investigate safety, tolerability, PK and PD of BI 655075 and to establish the BI 655075 dose(s) effective to reverse prolongation of blood coagulation time by dabigatran
- Trial name
- NCT01955720
- Testing
- BI 655075
- Where
- Belgium
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
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