Clinical trials: Condition
Depressive Disorder, Major
Does Nurse Semi Structured Interview Added to a rTMS Improve Patients With Major Depressive Disorder?
Repeated Transcranial Magnetic Stimulation - R.TMS - is currently part of the treatment for depressive illness. This non-invasive technique is designed to stimulate certain areas of the cerebral cortex involved in this pathology.
- Trial name
- DESTIMCARE (NCT03436823)
- Testing
- nurse semi-structured interview, Music & Relaxation with eyes closed
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Rennes University Hospital
Interstitial Lung Disease, Idiopathic Pulmonary Fibrosis
Prospective Validation of Cough, Dyspnea, and Quality of Life Questionnaires in Patients With IPF
The purpose of this study is to test cough, dyspnea (shortness of breath), and quality of life (QOL) questionnaires for their accuracy, sensitivity, and ability to reliably measure the severity of cough, breathlessness, and…
- Trial name
- NCT01874223
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Stanford University
Parkinson Disease
A Study of the Efficacy of IAMT as an Assessment Tool for Prediction of Progression of Parkinson's Disease
The primary objective of this proposal is to examine the efficacy of Improvised Active Music Therapy (IAMT) sessions as an early novel tool for cognitive and motor assessment for individuals with Parkinson's Disease (PD) in…
- Trial name
- Music Therapy (NCT05971459)
- Testing
- Improvised Active Music Therapy
- Where
- Canada
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Wilfrid Laurier University
Autoimmune Diseases
JY231(Internal Clinical Drug Code) Injection for the Treatment of Refractory Autoimmune Diseases
Early exploratory clinical study of the safety, tolerability and initial efficacy of JY231 injection in the treatment of refractory autoimmune diseases
- Trial name
- JY231、ADs (NCT06243159)
- Testing
- JY231
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Shanxi Bethune Hospital
Stone, Kidney
Endoscopic Combined Intrarenal Surgery Versus Multi-Tract Percutaneous Nephrolithotomy for Complex Renal Stones:
The aim of this study is to compare outcomes of endoscopic combined intrarenal surgery (ECIRS) with the multi-tract percutaneous nephrolithotomy for management of complex renal stones.
- Trial name
- NCT05460559
- Testing
- Group A (p-PCNL) procedure, Group B (s-ECIRS) procedure
- Where
- Egypt
- Volunteers
- 110 people
- Sponsor
- Mansoura University
Covid19
Safety and Preliminary Efficacy of the Combination of Niclosamide and Camostat
Niclosamide (2000 mg QD) and Camostate (600 mg QID) are expected to be safe and well-tolerated as a combination therapy and to show clinically beneficial for COVID-19 patients.
- Trial name
- NICCAM (NCT04750759)
- Testing
- Niclosamide + Camostat
- Where
- Germany
- Volunteers
- 4 people
- Sponsor
- Charité Research Organisation GmbH
Chronic Kidney Disease
The Effect of Citrasate Dialysate on Heparin Dose in Hemodialysis
An alternative to systemic heparin anticoagulation for HD is citrate dialysate (CD). CD contains a small amount of citric acid rather than acetic acid as the acidifying agent.
- Trial name
- NCT01466959
- Testing
- citrate dialysate (CD), acetic-acid based dialysate (AD)
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- University of Calgary
Type 2 Diabetes
Cognitive Protective Effect of Newer Antidiabetic Drugs
The proposed study aims to: 1. Explore the cognitive protective effects of SGLT2 inhibitors and DPP-4 inhibitors in patients attending diabetic clinics in Alexandria 2.
- Trial name
- NCT05347459
- Testing
- Dapagliflozin, Empagliflozin, Canagliflozin
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Lung Ultrasound, Heart Failure
B-lines-guided Heart Failure Management in Heart Failure Patients
Background：About 50% of subclinical heart failure (Sub-HF) patients might have residual lung ultrasound B-lines (LUS-BL). Sub-HF is insensitive to widely used imaging examinations, like x-ray or echocardiography, but lung…
- Trial name
- IMP-OUTCOME (NCT05035459)
- Testing
- lung ultrasound
- Where
- China
- Volunteers
- 320 people
- Sponsor
- Xiangtan Central Hospital
Adenocarcinoma of the Rectum, Stage II Rectal Cancer
Bevacizumab, Fluorouracil, and External-Beam Radiation Therapy in Treating Patients With Stage II or Stage III Rectal Cancer
This phase I trial is studying the side effects and best dose of bevacizumab when given together with fluorouracil and external-beam radiation therapy in treating patients with stage II or stage III rectal cancer.
- Conditions
- Adenocarcinoma of the Rectum, Stage II Rectal Cancer, Stage III Rectal Cancer
- Trial name
- NCT00052559
- Testing
- bevacizumab, fluorouracil, external beam radiation therapy
- Where
- 2 sites in United States
- Volunteers
- 32 people
- Sponsor
- National Cancer Institute (NCI)
Non-small Cell Lung Cancer
Nimotuzumab in Combination With Paclitaxel Liposome and Carboplatin (TP Regimen) for the Advanced NSCLC Patients
Nimotuzumab (hR3) is an IgG1 humanized monoclonal antibody that recognized an epitope located in the extra cellular domain of the human epidermal growth factor receptor (EGFR).
- Trial name
- NSCLC (NCT01393080)
- Testing
- Nimotuzumab and TP regimen, TP regimen
- Where
- China
- Volunteers
- 160 people
- Sponsor
- Tianjin Medical University Cancer Institute and Hospital
Stress Urinary Incontinence
Effects of Therapies in Women With Stress Urinary Incontinence
Purpose: This study aims to evaluate how surgical and medical treatments affect quality of life, depression status, and social participation in women with stress urinary incontinence (SUI).
- Trial name
- NCT06912880
- Testing
- trans obturator tape surgery
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people
- Sponsor
- Eastern Mediterranean University
Hyponatremia With Normal Extracellular Fluid Volume
Multicenter, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Efficacy and Safety of Oral Lixivaptan Capsules in Subject With Euvolemic Hyponatremia
The present study is designed to confirm and extend the observation from previous studies that lixivaptan therapy corrects hyponatremia, in euvolemic subject, including subjects with SIADH.
- Trial name
- NCT00660959
- Testing
- lixivaptan
- Where
- 71 sites in United States, Belgium and 4 more
- Volunteers
- 106 people
- Sponsor
- CardioKine Inc.
Asthma (Diagnosis)
Changing Lifestyle to Improve Quality of Life in Spanish Adolescents With Asthma
The goal of this clinical trial is to evaluate if a multicomponent lifestyle intervention can improve health-related quality of life in adolescents with asthma.
- Trial name
- CLiQ-Asthma (NCT07870980)
- Testing
- Lifestyle-change intervention
- Volunteers
- 96 people
- Sponsor
- Universitat Internacional de Catalunya
Hematological Toxicity, Targeted Therapy
Real-world Study on the Management of Hematological Toxicities Associated With Targeted Therapies for Breast Cancer
This multicenter, real-world, observational study will retrospectively and prospectively collect real-world data related to the investigational drugs.
- Conditions
- Hematological Toxicity, Targeted Therapy, Breast Cancer
- Trial name
- NCT06503380
- Testing
- No intervenrion.
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Fudan University
Relapsed/Refractory Systemic Light Chain Amyloidosis
A Trial to Learn if Linvoseltamab is Safe and Works in Adults With Relapsed or Refractory Systemic Light Chain Amyloidosis (AL Amyloidosis)
This study is researching an experimental drug called linvoseltamab ("study drug"). This study is focused on patients who have AL amyloidosis that has returned or have failed other therapies and need to be treated again.
- Trial name
- LINKER-AL2 (NCT06292780)
- Testing
- Linvoseltamab
- Where
- 21 sites in United States, Greece and 4 more
- Volunteers
- 220 people
- Sponsor
- Regeneron Pharmaceuticals
Sturge-Weber Syndrome
Trial of Sirolimus for Cognitive Impairment in Sturge-Weber Syndrome
The purpose of this research study is to gain a preliminary understanding of the safety of sirolimus in Sturge-Weber syndrome (SWS) and determine best outcomes to be used to assess the utility of sirolimus for the treatment of…
- Trial name
- NCT03047980
- Testing
- Sirolimus
- Where
- 2 sites in United States
- Volunteers
- 10 people
- Sponsor
- Anne Comi, MD
Asthma
A Single Dose Study to Assess the Regional Absorption and Bioavailability of 100mg GSK2190915A
GSK2190915 is a high affinity 5-lipoxygenase-activating protein (FLAP) inhibitor that attenuates the production of leukotrienes through the blockage of the first step in the leukotriene pathway, 5-lipoxygenase (5-LO) activation.
- Trial name
- NCT01318980
- Testing
- GSK2190915 100mg milled tablet, [14C] radiolabelled GSK2190915 solution, GSK2190915 100mg milled tablet administered to the proximal small bowel.
- Where
- United Kingdom
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Type 2 Diabetes Mellitus
Efficacy and Safety of Dorner Tablets and Aspirin for Prevention of Arteriosclerosis Progress in Type 2 Diabetes Mellitus Patients
The objective was to evaluate the efficacy and safety of combination of beraprost and aspirin for prevention of arteriosclerosis progress in type 2 diabetes mellitus patients.
- Trial name
- NCT02786979
- Testing
- Beraprost, Aspirin
- Where
- 6 sites in China
- Volunteers
- 190 people
- Sponsor
- Astellas Pharma Inc
Chronic Hepatitis C
CIFN and IFN γ-1b With or Without Ribavirin for Treatment of Chronic Hepatitis C (Nonresponders)
To evaluate the safety and tolerability of two different doses of Consensus Interferon-Alpha and Interferon Gamma-1b with or without ribavirin in patients with chronic hepatitis C who are non-responders to PEG-IFN-a 2a or…
- Trial name
- NCT00084279
- Testing
- Consensus Interferon-Alpha, Interferon Gamma-1b, Ribavirin
- Where
- United States
- Volunteers
- 81 people
- Sponsor
- InterMune
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.