Clinical trials: Condition
Henoch-Schoenlein Purpura
The Research of Standard Diagnosis and Treatment for Severe HSP in Children
This study is performed to evaluate the efficacy and safety of various measures in the treatment of severe HSP in children.
- Trial name
- NCT02540720
- Testing
- Dexamethasone, Gamma globulin, Hemoperfusion
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Nanjing Children's Hospital
Streptococcus Pneumoniae Infection
Effect of Two Versus Three Pneumococcal Conjugate Vaccinations
Two( 2) or three (3) instead of four vaccinations before the age of 6 months with pneumococcal conjugate vaccine are presumed to protect children against invasive pneumococcal disease like meningitis, at least on the short term…
- Trial name
- MNOES (NCT00189020)
- Testing
- PCV7
- Volunteers
- 1,005 people, healthy volunteers welcome
- Sponsor
- UMC Utrecht
Ondansetron
Ondansetron and the QT Interval In Adult Emergency Department Patients
The purpose of this study is to assess the use of the medication ondansetron (zofran) in the emergency department. There are studies of the ability of ondansetron to cause a prolongation in the QT interval (a certain measurement…
- Trial name
- NCT01759420
- Testing
- Ondansetron
- Where
- 2 sites in United States
- Volunteers
- 28 people
- Sponsor
- C.R.Darnall Army Medical Center
Alzheimer's Disease
AC-1204 Long-term Efficacy Response Trial (ALERT Protocol)
The study will evaluate the safety \& efficacy of AC-1204, a ketogenic compound, administered orally on a daily basis for 6 months.
- Trial name
- ALERT (NCT01211782)
- Testing
- caprylic triglyceride, long-chain triglyceride
- Where
- United States
- Sponsor
- Cerecin
Stroke
Effect of Pilates Training on Cognitive Functions in Patients With Stroke
The purpose of the present study is to investigate the effect of pilates training on cognitive functions in patient with stroke
- Trial name
- NCT04157582
- Testing
- Pilates training, Conventional physical therapy
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- October 6 University
Heart Failure, Iron Deficiency
Iron in Congestive Heart Failure
The hypothesis to be tested is whether treatment with intravenous iron (ferric carboxymaltose) will improve left-ventricular ejection fraction in patients with heart failure and iron deficiency as determined by cardiac magnetic…
- Conditions
- Heart Failure, Iron Deficiency, Anemia
- Trial name
- iCHF (NCT01837082)
- Testing
- ferric carboxymaltose
- Where
- 3 sites in Germany
- Volunteers
- 18 people
- Sponsor
- University of Ulm
Obesity
Intranasal Glucagon and Energy Balance
People who are overweight often find it difficult to lose weight through diet and medications because weight loss reduces the amount of energy spent by the body and increases appetite.
- Trial name
- INGEB (NCT03650582)
- Testing
- Glucagon
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University Health Network, Toronto
Caries,Dental, Broken Teeth
Evaluation of CAD/CAM Onlays Fabricated by Subtractive Versus Additive Digital Manufacturing Techniques.
Aim of the study: The aim of this RCT is to evaluate CAD/CAM onlays fabricated by subtractive technique (brilliant crios) versus additive technique (varseosmile crown plus material), in terms of clinical functional evaluation…
- Conditions
- Caries,Dental, Broken Teeth, Fracture Tooth, Defective Dentition
- Trial name
- NCT05943782
- Testing
- onlay manufactured by milling, Onlay manufactured by 3D printing
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Atrial Septal Aneurysm
Transcatheter Exclusion of Atrial-septal-aneurysm (TEA)
This study aims to investigate the safety and efficacy of transcatheter exclusion of atrial septal aneurysm (ASA) via transseptal perforation in patients with ASA.
- Trial name
- TEA (NCT04561882)
- Testing
- Transcatheter exclusion of atrial septal aneurysm
- Where
- 2 sites in China
- Volunteers
- 70 people
- Sponsor
- China National Center for Cardiovascular Diseases
Depression, Anxiety
Evaluation of Text Message Engagement Support of Mindfulness Smartphone Applications
The aim of this study is to assess the usability of two mindfulness smartphone applications (apps) and to evaluate whether text message support can promote engagement with those apps through a 4-week trial comparing support vs.
- Trial name
- NCT03633682
- Testing
- Headspace - Meditation and Mindfulness App, Stop, Breathe, & Think - Meditation and Mindfulness App
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Northwestern University
Healthy
Cortical Pharyngeal Area: Excitability, Facilitation and Plasticity in Healthy Subjects
The aims of this study are in four experimental sessions. The aims are: to characterize the excitability of the cortical pharyngeal area with pharyngeal pressure and electromyograms (EMGs), at rest, in awake healthy subjects; to…
- Trial name
- NCT00213382
- Where
- France
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University Hospital, Rouen
Dental Caries
Evaluation of Clinical Success of Restorations Using Different Magnification Aids
This study aimed to investigate the effect of using a loupe and dental operating microscope with different magnifications on the success of class II direct composite restorations.
- Trial name
- NCT05959382
- Testing
- Dental Loupe, Dental Operation Microscope
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Ataturk University
Orthostatic Hypotension, Spinal Cord Injury
Safety and Efficacy of L-NAME and Midodrine to Increase MAP
After a spinal cord injury the brain is no longer completely in control of the body below the level of injury. This affects many organs and systems in the body, we are interested in understanding how a spinal cord injury affects…
- Trial name
- NCT00835224
- Testing
- L-NAME, Midodrine
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- US Department of Veterans Affairs
Cervical Cancer, Prevention
Primary HPV-based Cervical Cancer Screening Algorithms in Botswana
Primary high-risk human papillomavirus (HPV) testing has become first line screening for cervical cancer in high-income countries.
- Trial name
- NCT04242823
- Testing
- 8-type HPV genotype restriction
- Where
- Botswana
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Beth Israel Deaconess Medical Center
Knee Osteoarthristis
Feasibility of Resting Intervals During Exercise Programs for Individuals With Knee Osteoarthritis
This pilot randomize trial tests the feasibility of administering two different exercise programs in people with knee osteoarthritis.
- Trial name
- CaRE (NCT06857123)
- Testing
- Exercise with Rest, Exercise without Rest
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Pittsburgh
Urinary Bladder Neoplasms, Transurethral Resection of the Bladder
Postoperative Quality of Recovery After Transurethral Resection of the Bladder
Transurethral resection of the bladder (TURB) is often performed as an outpatient procedure so high-quality postoperative recovery is particularly important.
- Conditions
- Urinary Bladder Neoplasms, Transurethral Resection of the Bladder, Postoperative Recovery
- Trial name
- NCT02534623
- Testing
- Spinal anesthesia, General anesthesia, bupivacaine
- Where
- Croatia
- Volunteers
- 70 people
- Sponsor
- General Hospital Zadar
Brain and Central Nervous System Tumors
Poly-ICLC in Treating Patients With Recurrent or Progressive Anaplastic Glioma
RATIONALE: Biological therapies such as poly-ICLC use different ways to stimulate the immune system and stop tumor cells from growing.
- Trial name
- NCT00058123
- Testing
- poly ICLC
- Where
- 8 sites in United States
- Volunteers
- 55 people
- Sponsor
- Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Headache, Migraine
Study of Intramuscular Ropivacaine Injections for Treatment of Pediatric Headache
Objective: To determine if lower paracervical intramuscular ropivacaine injection is an effective treatment for pediatric headache in an emergency department setting.
- Trial name
- NCT00680823
- Testing
- Ropivacaine, Normal saline
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Robert Hickey
Treatment Resistant Depression
Neurobiological Analyses Within the FORESEE III Study
In this observational, non-invasive clinical study different neurobiological analyses will be performed in a group of patients with severe treatment resistant major depression participating in an efficacy study of deep brain…
- Trial name
- NCT04021823
- Where
- Germany
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University Hospital Freiburg
Substance-related Disorders
Project CHOICE: Efficacy Testing of CHOICE and CHOICE+Normative Feedback Interventions
This study will use a pilot test format to examine the efficacy of a brief Motivational Interviewing (MI) intervention developed by the investigator Dr.
- Trial name
- CHOICE (NCT02083523)
- Testing
- Motivational Interview with Normative Feedback, Motivational Interview
- Volunteers
- 48 people
- Sponsor
- University of Illinois at Urbana-Champaign
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