Clinical trials: Conditioning Therapy
Eating Disorder
Treatment Outcome in Eating Disorders
Do the current eating disorder treatments, i.e., Family-based Treatment (FBT) and Enhanced Cognitive behavioral therapy (CBT-E), offered at the Center for the Treatment of Eating Disorders (CTED) demonstrate effectiveness?…
- Trial name
- NCT03599921
- Testing
- Family-based treatment, Enhanced Cognitive behavioral therapy, Family-based treatment modified for ARFID
- Volunteers
- 275 people
- Sponsor
- Children's Hospitals and Clinics of Minnesota
Overweight, Obesity
Sharing Digital Self-Monitoring Data With Others to Enhance Long-Term Weight Loss
Adults attempting weight loss through lifestyle modification (LM) typically find maintenance of behavior change difficult. Outcomes might be improved if participants are provided with sustained sources of accountability and…
- Trial name
- FitLink (NCT05180448)
- Testing
- Coach Share On, Group Share On, Friend/Family Share On
- Where
- United States
- Volunteers
- 321 people, healthy volunteers welcome
- Sponsor
- Drexel University
Primary Insomnia, Depressive Disorders With Insomnia
Enhancing Performance of Cognitive Behavioral Therapy for Insomnia With an Integrative Mobile Platform
Cognitive Behavioral Therapy for Insomnia (CBT-I) has been proven as an effective intervention for the non-pharmacological treatment of insomnia.
- Trial name
- NCT01978626
- Testing
- App modules, Traditional CBT-I
- Where
- Taiwan
- Volunteers
- 120 people
- Sponsor
- National Taiwan University Hospital
Obsessive-Compulsive Disorder
Effectiveness of Sertraline and Cognitive Behavioral Therapy in Treating Pediatric Obsessive-Compulsive Disorder
This study measures the occurrence of certain side effects linked to antidepressant use and evaluates the effectiveness of the medication sertraline plus cognitive behavioral therapy to treat people with obsessive-compulsive…
- Trial name
- NCT00382291
- Testing
- Regular Titration, Slow Titration
- Where
- 2 sites in United States
- Volunteers
- 56 people
- Sponsor
- University of Florida
Anorexia Nervosa, Caregiver Burden
Online FBT-DBT Caregiver Intervention for Caregivers of Individuals With Anorexia Nervosa
Anorexia nervosa (AN) is a severe psychiatric disorder characterized by a chronic and relapsing course. Caregivers of individuals with AN often experience substantial caregiving burden, emotional distress, and impairment in…
- Trial name
- NCT07734779
- Testing
- Online FBT-DBT Intervention, Online Supportive Psychological Intervention
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Shanghai Mental Health Center
Acute Myeloid Leukemia, Acute Undifferentiated Leukemia
Chemotherapy (Decitabine in Combination With FLAG-Ida) and Total-Body Irradiation Followed by Donor Stem Cell Transplant for the Treatment of Adults With Myeloid Malignancies at High Risk of Relapse
This phase I/II trial studies the safety, side effects, and best dose of decitabine in combination with fludarabine, cytarabine, filgrastim, and idarubicin (FLAG-Ida) and total body irradiation (TBI) followed by a donor stem cell…
- Conditions
- Acute Myeloid Leukemia, Acute Undifferentiated Leukemia, Mixed Phenotype Acute Leukemia, Recurrent Acute Myeloid Leukemia
- Trial name
- NCT06928662
- Testing
- Decitabine, Bone Marrow Aspiration, Bone Marrow Biopsy
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Fred Hutchinson Cancer Center
Multiple Sclerosis
Study of Behavioral Modification Program and Mirabegron to Improve Urinary Urgency in Multiple Sclerosis
The purpose of this study is to determine if treatment with Mirabegron will improve urinary urgency control beyond that achieved with pelvic floor exercises alone
- Trial name
- MIRROR (NCT02086188)
- Testing
- Mirabegron
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- Theodore R. Brown, MD MPH
Rumination, Cognitive Avoidance
The Effectiveness of Dialectical Behavior Therapy on Rumination and Cognitive Avoidance in Teachers
This randomized controlled trial evaluated the effectiveness of Dialectical Behavior Therapy (DBT) skills training in reducing rumination and cognitive avoidance among middle-school teachers in Isfahan, Iran.
- Trial name
- NCT07650617
- Testing
- Dialectical Behavior Therapy Skills Training
- Where
- Iran
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Islamic Azad University, Sanandaj
Autism Spectrum Disorder
Parent-mediated Developmental Behavioral Intervention
This study explores the effectiveness of two intervention programs: "Long-distance developmental behavioral intervention" and "developmental behavioral interventions" for children with autism spectrum disorder or multiple…
- Trial name
- PDBI (NCT03812068)
- Testing
- Long-distance developmental behavioral intervention, Developmental behavioral intervention
- Where
- Taiwan
- Volunteers
- 120 people
- Sponsor
- National Taiwan University Hospital
Depression, Anxiety
Preventing Depression and Anxiety: A Cystic Fibrosis-Specific Cognitive Behavioral Therapy Intervention
Individuals with Cystic Fibrosis (CF) are at high risk for depression and anxiety, with negative consequences for quality of life, ability to carry out daily CF treatments, and health.
- Trial name
- NCT03992027
- Testing
- CF-CBT: A Cognitive-Behavioral Skills-Based Program to Promote Emotional Well-Being for Adults wtih Cystic Fibrosis, Waitlist Control
- Where
- 4 sites in United States
- Volunteers
- 60 people
- Sponsor
- Massachusetts General Hospital
Online CBT Targeting Cardiac Anxiety
Online Cognitive Behavioral Therapy Targeting Cardiac Anxiety
The purpose of the present study is to evaluate an internet-delivered exposure-based cognitive behavioral therapy (CBT) protocol tailored for patients following myocardial infaction (MI) to increase Quality of Life (Qol) and…
- Trial name
- MI-CBT (NCT05580718)
- Testing
- MI-CBT
- Where
- Sweden
- Volunteers
- 96 people
- Sponsor
- Karolinska Institutet
HIV Infections, Depression
Effectiveness of a Telephone-Delivered Behavioral Treatment to Improve the Quality of Life of Older Adults With HIV
This study will evaluate the effectiveness of a telephone-delivered coping improvement group intervention in improving quality of life in older adults with HIV.
- Trial name
- NCT00365690
- Testing
- Telephone-administered coping improvement therapy, Telephone-administered supportive-expressive therapy, Individual therapy
- Where
- United States
- Volunteers
- 360 people
- Sponsor
- Ohio University
Pelvic Floor Disorders, Anxiety
Enhancing Behavioral Treatment for Women With Pelvic Floor Disorders
The purpose of this proposal is to test a novel behavioral treatment - Unified Protocol Cognitive-Behavior Therapy (UP-CBT)1 - to enhance quality of life in women with pelvic floor disorders.
- Conditions
- Pelvic Floor Disorders, Anxiety, Urinary Urgency, Urinary Incontinence
- Trial name
- NCT03623880
- Testing
- Unified Protocol, Supportive Therapy
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- Northwestern University
Functional Gastrointestinal Disorders
Internet-delivered CBT for Children With Functional Gastrointestinal Disorders - an Open Pilot Study
This pilot-study aims to evaluate the effect size and feasibility of internet-delivered cognitive behavior therapy (ICBT) for children (age 8-12 years) with pain-predominant functional gastrointestinal disorders (e.g.
- Trial name
- NCT02475096
- Testing
- Internet-delivered CBT
- Where
- 2 sites in Sweden
- Volunteers
- 31 people
- Sponsor
- Karolinska Institutet
Pancreatitis, Chronic Pancreatitis
Internet-Delivered Pain Self-Management for Persons With Acute Recurrent and Chronic Pancreatitis Pain
Severe and disabling abdominal pain is common in individuals with chronic pancreatitis. Although pain is associated with reduced quality of life and high economic and societal costs, there are limited effective options for pain…
- Conditions
- Pancreatitis, Chronic Pancreatitis, Acute Recurrent Pancreatitis
- Trial name
- IMPACT-2 (NCT06386224)
- Testing
- Internet-delivered pain self-management (CBT Condition), Education Program
- Where
- United States
- Volunteers
- 280 people
- Sponsor
- Seattle Children's Hospital
End-of-life, Depression, Anxiety
Improve Mental Health and Emotional Labor Among Nurses Who Care the End-of-life Patients
CBT: cognitive behavioural therapy MBT: mindfulness-based therapy
- Trial name
- NCT05541523
- Testing
- cognitive behavioural therapy, mindfulness-based therapy
- Where
- 2 sites in China
- Volunteers
- 100 people
- Sponsor
- Huichao Zhang
Chronic Insomnia
A Remote, 9-week Insomnia Treatment Trial to Collect Real World Data for a Digital Therapeutic
The purpose of the study is to collect data in a real-world environment, for a digital therapeutic that delivers CBT-I through a decentralized clinical trial, open to participants with chronic insomnia.
- Trial name
- DREAM (NCT04325464)
- Testing
- PEAR-003A
- Where
- United States
- Volunteers
- 1,590 people
- Sponsor
- Pear Therapeutics, Inc.
Depression, Trauma
Group-integrated Cognitive Behavioural Therapy (Gi-CBT) to Aid Communities' Reintegration of Former Terrorists in Nigeria: A Randomised Control Trial
The project aims to make significant contributions that change the conversation in communities and policy circles through promoting knowledge of nonviolent peace strategies using the Group integrated Cognitive Behavioural Therapy…
- Conditions
- Depression, Trauma, Anxiety, Fear
- Trial name
- NCT05640921
- Testing
- Gi-CBT, Media Orientation
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Teesside University
Chronic Insomnia Disorder, Chronic Insomnia
A Randomized, Single-Blind Study Evaluating the Efficacy and Cost-Effectiveness of Brief Behavioral Therapy for Chronic Insomnia Patients Under Medication Treatment At Nguyen Trai Hospital, Ho Chi Minh City
Insomnia disorder is considered quite common and is recognized as a risk factor for psychiatric disorders. In industrialized countries, chronic insomnia disorder is estimated to affect about 5-10% of the population, with some…
- Conditions
- Chronic Insomnia Disorder, Chronic Insomnia, BBT-I, CBT-I
- Trial name
- NCT06727916
- Testing
- BBT-I, Non BBT-I
- Volunteers
- 100 people
- Sponsor
- Nguyen Trai Hospital
Functional Aging, Subjective Cognitive Concerns
A Multidimensional Behavioral Intervention for Those at Risk for Alzheimer's Dementia
This intervention is designed to promote enhanced use of compensation strategies including calendar and task list use, and organization systems, as well as increased engagement with brain health activities including physical…
- Conditions
- Functional Aging, Subjective Cognitive Concerns, Compensation Strategies, Brain Health Activities
- Trial name
- NCT03549078
- Testing
- Intervention
- Where
- United States
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- University of California, Davis