Clinical trials: Conduct
Solid Tumor, Childhood, Brain Tumor, Pediatric
Social Emotional Development in Young Children With Cancer
Many children with cancer are diagnosed in early childhood, and as such, will likely miss key social experiences such as participation in preschool or kindergarten, playing on playgrounds, and other normative experiences.
- Trial name
- NCT03086421
- Testing
- Questionnaires
- Where
- United States
- Volunteers
- 119 people
- Sponsor
- St. Jude Children's Research Hospital
Substance Use Disorder (SUD), Treatment Adherence
Dynamic Multilevel Processes of Recovery in Therapeutic Communities in Mexico (DICO Model)
This study aims to develop and empirically evaluate the Dinámica Integral Conductual Comunitaria (DICO) model, a multilevel framework that conceptualizes recovery from substance use disorders as a dynamic process emerging from…
- Trial name
- DICO (NCT07588516)
- Testing
- Ecological Momentary Assessment (EMA)
- Where
- Mexico
- Volunteers
- 60 people
- Sponsor
- Under The Tree Therapeutic Community
Adherence, Tobacco Use Cessation
Smoking Cessation for Young Adults Who Binge Drink - 1
The purpose of this study is develop and test the success of a new smoking cessation intervention that includes a component to eliminate binge drinking.
- Conditions
- Adherence, Tobacco Use Cessation, Alcohol & Drug Use, Nicotine Transdermal System
- Trial name
- NCT00218452
- Testing
- Lifestyle counseling
- Where
- 3 sites in United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Suicide, Suicide Attempt
Lock and Protect: Reducing Adolescent Access to Lethal Means of Suicide
The primary goal is to determine the acceptability and feasibility of implementing the Lock and Protect decision aid. The secondary goals are to identify the potential short-term impact of Lock and Protect on home firearm and…
- Conditions
- Suicide, Suicide Attempt, Adolescent Suicidality, Suicide Ideation
- Trial name
- NCT07111052
- Testing
- Lock and Protect is a self-administered, web-based decision aid for caregivers of adolescents at risk for suicide.
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Columbia University
Depression
Trial to Determine the Maximum Tolerated Dose (MTD) Based on Safety and Tolerability, of Org 26576 in Participants With Major Depressive Disorder (174001/P05704/MK-8777-001)
Trial to determine the maximum tolerated dose (MTD) based on safety and tolerability of MK-8777 (Org 26576, SCH 900777) in participants with major depressive disorder.
- Trial name
- NCT00610649
- Testing
- MK-8777
- Volunteers
- 54 people
- Sponsor
- Merck Sharp & Dohme LLC
Cognitive/Functional Effects, Delirium
Donepezil and Vitamin E to Prevent Side Effects Caused By Radiation Therapy to the Head in Patients Receiving Treatment for Small Cell Lung Cancer
RATIONALE: Donepezil and vitamin E may be able to decrease side effects caused by radiation therapy given to prevent brain metastases in patients with small cell lung cancer.
- Conditions
- Cognitive/Functional Effects, Delirium, Depression, Lung Cancer
- Trial name
- NCT00006349
- Testing
- vitamin E, donepezil hydrochloride
- Where
- 15 sites in United States
- Volunteers
- 9 people
- Sponsor
- Alliance for Clinical Trials in Oncology
Transsexualism, Transgenderism
Effects of Cross-sex Hormone Therapy on Eating Behavior, Metabolism, Energy Balance and Cardiovascular System
Current study aims to characterize five highly interconnected physiological systems in patients undergoing cross-sex hormone therapy - namely glucose and lipid metabolism, energy balance, eating behavior, functional brain…
- Conditions
- Transsexualism, Transgenderism, Adiposity, Eating Behavior
- Trial name
- HHS (NCT04838249)
- Where
- Germany
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Leipzig
Well-Being, Psychological, Engagement
The Impact of the Family Room App on Caregivers
Engaging families in patient care during serious illness can enhance care quality, reduce social isolation, boost satisfaction, and lower healthcare costs.
- Conditions
- Well-Being, Psychological, Engagement, Satisfaction, Consumer
- Trial name
- NCT06463158
- Testing
- Family Room Application
- Where
- 2 sites in United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Nebraska
Mild Cognitive Impairment, Cognitive Decline
Exercise in Adults With Mild Memory Problems
This study evaluates the effects of physical exercise on cognition, functional status, brain atrophy and blood flow, and cerebrospinal fluid biomarkers of Alzheimer's disease in adults with a mild memory impairment.
- Conditions
- Mild Cognitive Impairment, Cognitive Decline, Memory Impairment
- Trial name
- EXERT (NCT02814526)
- Testing
- Aerobic exercise, Stretching/balance/range of motion exercise
- Where
- 14 sites in United States
- Volunteers
- 296 people
- Sponsor
- Alzheimer's Disease Cooperative Study (ADCS)
Primary Insomnia, Depressive Disorders With Insomnia
Enhancing Performance of Cognitive Behavioral Therapy for Insomnia With an Integrative Mobile Platform
Cognitive Behavioral Therapy for Insomnia (CBT-I) has been proven as an effective intervention for the non-pharmacological treatment of insomnia.
- Trial name
- NCT01978626
- Testing
- App modules, Traditional CBT-I
- Where
- Taiwan
- Volunteers
- 120 people
- Sponsor
- National Taiwan University Hospital
Insomnia Chronic, Insomnia
Effects of Insomnia Treatment on Metabolism in Patients With Depression
This project will examine changes in metabolism and depressive symptoms after receiving CBT-I in 30 subjects with insomnia disorder and MDD.
- Conditions
- Insomnia Chronic, Insomnia, Insomnia, Primary, Depression
- Trial name
- NCT04719143
- Testing
- Cognitive Behavioral Therapy for Insomnia (CBT-I)
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Pennsylvania
Develop a New Group Version of the Becker-DeGroot-Marsckek (BDM) Auction to Measure Willingness to Pay of Compound Members for Shared Hardware., Develop a New Survey Instrument to Measure Behavioural Determinants of Hand Washing and Water Treatment Like Disgust and Shame or Social Pressure.
Disgust and Shame Based Safe Water and Handwashing Promotion
An estimated 2.2 million children under the age of 5 years die from diarrheal disease each year. Most of the burden of diarrheal disease is thought to be preventable with improvements in sanitation, water quality, and hygiene.
- Conditions
- Develop a New Group Version of the Becker-DeGroot-Marsckek (BDM) Auction to Measure Willingness to Pay of Compound Members for Shared Hardware., Develop a New Survey Instrument to Measure Behavioural Determinants of Hand Washing and Water Treatment Like Disgust and Shame or Social Pressure., Identify New Methods for Measuring Hand Washing and Water Treatment Behaviour., Compare the Effectiveness of the Disgust and Shame Based Interventions With Standard Public Health Interventions.
- Trial name
- NCT02037243
- Testing
- Standard Public Health Intervention with Water Treatment, Standard Public Health Intervention with Water Treatment & Hand Washing
- Where
- Bangladesh
- Volunteers
- 420 people, healthy volunteers welcome
- Sponsor
- International Centre for Diarrhoeal Disease Research, Bangladesh
Rejection Sensitivity
Endogenous Opioid Mechanisms for Rejection Sensitivity
This project hypothesizes that the brain's opioid system determines rejection sensitivity, a personality trait that is a vulnerability factor and feature of several psychiatric disorders.
- Trial name
- NCT02189785
- Where
- United States
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- Stony Brook University
Diabetes Mellitus, Type 2
Progressive Relaxation Exercise on Sleep Quality in Patients With Type 2 Diabetes
The purpose of this study is to evaluate the effect of progressive relief exercise on sleep quality in patients with type 2 diabetes.
- Trial name
- NCT05956743
- Testing
- progressive relaxation exercise sessions
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Mersin University
Disruptive Global Behavior During Previous Treatment Visits
Behavior Management Using Audiovisual Tools
The aim of the study was to assess whether the behavior, anxiety, and pain of pediatric patients during dental treatment improves when a cartoon film is viewed or a videogame is played as methods of distraction.
- Trial name
- NCT01643915
- Testing
- No distraction method, Distraction method
- Where
- Spain
- Volunteers
- 224 people, healthy volunteers welcome
- Sponsor
- Universitat Internacional de Catalunya
Child, Preschool
Fit, Healthy and Smart Preschool Children: PREFIT-Chile
Introduction: Investigating the interrelationship between physical condition, non-invasive health markers and executive function in preschoolers, is based on the current health and cognitive development situation of this…
- Trial name
- PREFIT-Chile (NCT04269135)
- Where
- Chile
- Volunteers
- 868 people, healthy volunteers welcome
- Sponsor
- Playa Ancha University
Emotional Distress, Burnout, Professional
A Self-directed Mobile Mindfulness Intervention to Address Distress and Burnout in Frontline Healthcare Workers
This is a pilot randomized waitlist control trial assessing if the feasibility of using a mobile mindfulness app to treat emotional distress and burnout amongst nurses taking care of COVID-19 patients.
- Conditions
- Emotional Distress, Burnout, Professional, Stress, Job, Anxiety
- Trial name
- LIFT-HCW (NCT04816708)
- Testing
- LIFT Mindfulness
- Where
- United States
- Volunteers
- 102 people
- Sponsor
- Duke University
Chronic Low Back Pain (CLBP)
Neuroimmune Responses to Exercise in Chronic Back Pain
The goal of this mechanistic clinical trial is to learn how physical exercise affects the body and brain in people with chronic low back pain.
- Trial name
- eCLBP (NCT07497425)
- Testing
- Physical Exercise
- Where
- Canada
- Volunteers
- 216 people, healthy volunteers welcome
- Sponsor
- McGill University
Breast Cancer Female, Mammography Screening
Investigating Barriers for Decision Making in a Danish Breast Cancer Screening Context
The aim is to investigate potential barriers to informed decision making in a breast cancer screening context. This is a necessary step prior to developing and investigating improved information or decision aids in a Danish…
- Conditions
- Breast Cancer Female, Mammography Screening, Decision Making, Information Seeking Behavior
- Trial name
- NCT05444725
- Testing
- Stage of Decision Making, Choice framing, Opportunity Framing
- Where
- Denmark
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Diet, Healthy, Eating Behavior
SEP and the Impact of Portion Size on Daily Energy Intake
Reducing food portion size is a potential strategy to reduce energy intake. There is some evidence to suggest that individuals with lower socioeconomic position (SEP) intend to eat more from larger portions, suggesting that the…
- Conditions
- Diet, Healthy, Eating Behavior, Obesity
- Trial name
- NCT05173376
- Testing
- Portion size manipulation
- Where
- United Kingdom
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- University of Liverpool
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