Clinical trials: Conduct
Procedural Sedation, Behavior Disorders
The Use of Dexmedetomidine for EEG Sedation in Children With Behavioural Disorders
Children's compliance during diagnostic or therapeutic procedures is a challenge, often requiring the use of sedative and/or analgesic drugs.
- Trial name
- NCT03799783
- Testing
- dexmedetomidine
- Where
- Italy
- Volunteers
- 19 people
- Sponsor
- Azienda Ospedaliera di Padova
Preventable Disease, Vaccine, Health Care Utilization
Effect of Varied Outreach Methods on Appointment Scheduling, Appointment Completion, and Receipt of MMR Vaccination
Our objective is to determine the effectiveness of varied outreach methods (e.g. automated reminder calls/text messages with or without personalized calls/texts) to children age 12-14 months or 4 years old who are due for a WCC…
- Trial name
- NCT04567342
- Testing
- 1 automated message, 2 automated messages, No personal contact attempt
- Where
- United States
- Volunteers
- 1,312 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Alcoholism
A Study on the Biobehavioral Mechanisms of Baclofen and Alcohol Drinking
This pilot trial has the goal to demonstrate the feasibility of a study to test the effects of baclofen in a laboratory experiment using cue-reactivity and alcohol-self administration paradigms in non-treatment seeking…
- Trial name
- NCT01076283
- Testing
- Baclofen, Cyproheptadine
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Brown University
Childhood Traumatic Grief, Post Traumatic Stress
Randomized Controlled Trial of Trauma-focused CBT in Tanzania and Kenya
The primary goal is to study the effectiveness of Trauma-focused Cognitive Behavioral Therapy (TF-CBT) in treating traumatic grief and traumatic stress for orphaned children and young adolescents in two East African sites with…
- Conditions
- Childhood Traumatic Grief, Post Traumatic Stress, Post Traumatic Stress Disorder, Depressive Symptoms
- Trial name
- NCT01822366
- Testing
- Trauma-focused Cognitive Behavioral Therapy
- Where
- 3 sites in United States, Kenya and 1 more
- Volunteers
- 1,280 people
- Sponsor
- Duke University
Posttraumatic Stress Disorder, PTSD
D-cycloserine Adjunctive Treatment for Posttraumatic Stress Disorder (PTSD) in Adolescents
The purpose of this study is to show whether D-cycloserine in combination with cognitive behavioral therapy (CBT) is more effective than CBT plus placebo to reduce symptoms of posttraumatic stress disorder (PTSD) in 13-18…
- Trial name
- NCT01157429
- Testing
- D-cycloserine, CBT
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Tulane University School of Medicine
Alzheimer's Disease and Related Dementias
Pilot Testing Dementia-Enhanced Training and Tool for Home Hospice Clinicians
The purpose of this study is to pilot test the feasibility, acceptability, and preliminary efficacy of a clinically useful, inclusive dementia-enhanced training and tool for use by home hospice clinicians to improve care and…
- Trial name
- EDITH-HC (NCT05719077)
- Testing
- EDITH-HC
- Where
- United States
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey
Chronic Disease, Medication Adherence
Impact of Pillboxes on Medical Adherence
This study uses an experimental design to test the impact of different types of pillboxes on medication adherence. Participants in this study will randomized to receive one of the three pillbox interventions: 1) A standard seven…
- Trial name
- NCT03861845
- Testing
- Standard off-the-shelf pillbox, Custom off-the-shelf pillbox, Custom designed and manufactured pillbox
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Florida International University
Schizophrenia, Impulsive Behavior
Effects of Transdermal Nicotine on Response Inhibition to Emotional Cues in Schizophrenia
The purpose of this study is to test whether nicotine, a drug that activates receptors called nicotinic acetylcholine receptors in the brain, improves the ability to make or withhold responses to faces that are either emotionally…
- Trial name
- NCT03838484
- Testing
- Nicotine Patch, 7 Mg/24 Hr
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Agitation
Acupuncture to Improve Comfort of Children on a Ventilator in the Intensive Care Unit
The purpose of this study is to determine whether acupuncture is effective at improving comfort in children on a ventilator in the intensive care unit.
- Trial name
- NCT01848158
- Testing
- acupuncture
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Seattle Children's Hospital
Energy Intake, Food Intake
The Acute Effect of Vaping on Food Intake
This study assesses the acute effects of a standardized 20-minute vaping episode compared to a non-vaping control condition on ad libitum food intake during a 30-minute buffet meal, occurring approximately 45 minutes after the…
- Conditions
- Energy Intake, Food Intake, E-Cig Use, Appetite
- Trial name
- NCT04219189
- Testing
- Vaping condition, Control condition
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Virginia Commonwealth University
Major Depressive Disorder
Safety and Efficacy of Levomilnacipran ER (F2695 SR) in Major Depressive Disorder
The purpose of this study is to evaluate the efficacy, safety, and tolerability of Levomilnacipran ER versus placebo in the treatment of outpatients with major depressive disorder.
- Trial name
- NCT00969150
- Testing
- Levomilnacipran ER
- Where
- 25 sites in United States
- Volunteers
- 362 people
- Sponsor
- Forest Laboratories
Older Adults, Anxiety
Behavioral Activation and Medication Optimization for Perioperative Mental Health Feasibility Study
Inadequate management of preoperative mental health disorders often contributes to poor postoperative outcomes, including increased rates of readmission, delirium, falls, and mortality.
- Conditions
- Older Adults, Anxiety, Depression, Cardiac Surgery
- Trial name
- NCT05110690
- Testing
- Behavioral Activation, Medication Optimization
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Washington University School of Medicine
Child Development
Early Literacy Promotion Intervention
This study is testing the effects of early literacy promotion compared to standard literacy promotion at The Children's Hospital of Philadelphia.
- Trial name
- ELPI (NCT02713659)
- Testing
- Early Literacy Promotion, Standard Literacy Promotion
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Philadelphia
Hand Hygiene
ProvodineTM Decreases Hand Contamination
The purpose of this study is to see whether Provodine, an FDA approved product, provides long-lasting protection on the hands of staff who provide anesthesia for patients.
- Trial name
- NCT04023682
- Testing
- Provodine Hand Sanitizer
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Sundara Reddy
Sexual Behavior, Alcohol Drinking
Men's Sexual Risk Behaviors: Alcohol, Sexual Aggression, and Emotional Factors
Although correct, consistent condom use can greatly reduce sexually transmitted infections and unplanned pregnancies, resistance of condom use is common among young adults.
- Conditions
- Sexual Behavior, Alcohol Drinking, Sexual Aggression, Emotions
- Trial name
- NCT03900650
- Testing
- High provocation manipulation, Low provocation manipulation, Alcoholic beverage
- Where
- United States
- Volunteers
- 420 people
- Sponsor
- Arizona State University
Depression, Major Depressive Episode
Study Comparing Magnetic Seizure Therapy (MST) to Electroconvulsive Therapy (ECT) for Depression in Older Adults
To evaluate the feasibility, tolerability and efficacy of Magnetic Seizure Therapy (MST) in elderly patients with a major depressive episode, who are randomly assigned to receive an acute course of MST or ECT.
- Conditions
- Depression, Major Depressive Episode, Bipolar Disorder
- Trial name
- MSTvsEST (NCT01869374)
- Testing
- MagVenture MagPro MST, RUL ECT
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- New York State Psychiatric Institute
Schizophrenia, Schizophreniform Disorder
DECIFER: Depression and Citalopram In First Episode Recovery
This study seeks to examine the effectiveness of citalopram added to treatment with any oral or injectable second-generation antipsychotic plus standardized psychoeducation in first episode schizophrenia patients.
- Trial name
- DECIFER (NCT01041274)
- Testing
- Citalopram, Psychoeducation, Cognitive Behavioral Therapy (CBT)
- Where
- United States
- Volunteers
- 95 people
- Sponsor
- NYU Langone Health
Anxiety Depression, Disability Physical
Exploratory Study for Toivoa-001 on Human Factors
The Study will evaluate Rauha as an experimental digital therapeutic for persons with Disabilities suffering from anxiety and/or depression.
- Trial name
- NCT06477913
- Testing
- Rauha
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Toivoa Inc
Depression, Anxiety
Community Intervention to Improve Depressive Symptoms Among Older Adults (VIDACTIVA)
The goal of this pilot trial is to test how feasible is to conduct a large clinical trial that evaluate both implementation and effectiveness outcomes of a community-based interventions for older adults with depression in…
- Trial name
- VIDACTIVA1 (NCT06065020)
- Testing
- VIDACTIVA sessions, Standard Care
- Where
- Peru
- Volunteers
- 72 people
- Sponsor
- Universidad de San Martín de Porres
Suicide
Suicide Prevention Intervention for Vulnerable Emerging Adult Sexual Minorities
Emerging adult sexual minorities (EASM) are vulnerable to stressors that increase risk for suicidal ideation and behaviors. The investigators will examine a mobile application that leverages skills coaching and peer mentoring to…
- Trial name
- NCT05018143
- Testing
- STARS, Control condition
- Where
- United States
- Volunteers
- 64 people
- Sponsor
- University of Pennsylvania
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