Clinical trials: Conduct
Low Anterior Resection Syndrome
Paula Method of Exercises in Patients With LARS Syndrome:Randomized Controlled Trial
Sphincter sparing rectal resection surgery, either total mesorectal excision (TME) with a temporary loop ileostomy or partial mesorectal excision (PME), is the mainstay of rectal cancer treatment , however, these treatments are…
- Trial name
- NCT05682157
- Testing
- Paula Method of muscle exercises
- Where
- 2 sites in Israel
- Volunteers
- 62 people
- Sponsor
- Hadassah Medical Organization
Procrastination
How to Help Students Overcome Academic Procrastination
The purpose of this study is to evaluate two different treatment methods in a sample of procrastinating students of the University of Basel and the University of Applied Sciences and Arts Northwestern Switzerland.
- Trial name
- NCT05730101
- Testing
- Cognitive-behavioral treatment (CBT), Imaginary pill treatment (IP)
- Where
- Switzerland
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Medication Adherence
Effect of Community Pharmacist Intervention on Adherence to Long-Term Medications
The 4-arm factorial design RCT tested the impact of a behavioral intervention (SBI or BI), a reminder device (Pillbox), and the combination of the two on adherence in adult patients who filled a prescription for oral medications…
- Trial name
- ECO-PHIL (NCT02604901)
- Testing
- Screening and Brief Intervention (BI), Pill Box (PB)
- Where
- 2 sites in United States
- Volunteers
- 1,091 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Educational Activities
The Effect Of Education Given According to Meleıs' Transitional Theory to Patients With Pacemaker
This study will be carried out to determine the effect of training given according to Meleis's Transition Theory to patients with pacemaker implantation on anxiety, depression and self-efficacy levels.
- Trial name
- NCT06204601
- Testing
- Education According to Meleis' Transitional Theory to Patients With Pacemaker
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Ordu University
Anxiety, Depression
Electroencephalographic Study of the Mechanisms of Inhibition of Emotional Memories in Young Healthy Subjects
Forgetfulness has long been considered a pathology of memory. However, the brain's voluntary suppression of certain unpleasant memories is essential for building a healthy memory.
- Conditions
- Anxiety, Depression, Cognitive Control
- Trial name
- ENGRAMME (NCT06891612)
- Testing
- Cognitive Assessments, Eye-tracking, Electroencephalography (EEG)
- Where
- France
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Non-cardiac Chest Pain, Cardiac Anxiety
Internet-delivered CBT for Patients With NCCP
Non-cardiac chest pain (NCCP) is common and has substantial impact on patients' psychological wellbeing, quality of life and healthcare use.
- Trial name
- IKSIT (NCT03336112)
- Testing
- Internet-delivered cognitive behavioral therapy (I-CBT), Information program
- Where
- Sweden
- Volunteers
- 109 people
- Sponsor
- Linkoeping University
Cancer, Anxiety
Group Metacognitive Therapy for Anxiety and Depression in Cancer Survivors
This study aims to test the potential of group metacognitive therapy in alleviating emotional distress in cancer survivors. The investigators aim to find out if a group based approach is acceptable to patients and feasible to…
- Conditions
- Cancer, Anxiety, Depression, Quality of Life
- Trial name
- GMAC (NCT03424512)
- Testing
- Group Metacognitive Therapy
- Where
- United Kingdom
- Volunteers
- 15 people
- Sponsor
- University of Liverpool
Malaligned Teeth, Crowding of Teeth
Effect of Different Adhesive Systems on White Spot Lesions During Fixed Orthodontic Treatment
The primary goal of this study is to compare the number of white spot lesions during fixed appliance therapy between self-etch and one-step bonding systems.
- Trial name
- NCT07753512
- Testing
- Self-etch adhesive, One-Step Adhesive, Conventional Bonding Technique
- Where
- Pakistan
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Foundation University Islamabad
Breast Cancer, Mastectomy; Lymphedema
Examining the Cosmetic Results, Quality of Life and Patient Satisfaction Achieved With Skin Reducing Nipple Sparing Mastectomy and Implant Based Breast Reconstruction, and Comparing it to Classic Skin- Sparing Mastectomy and Implant- Based Breast Reconstructive Surgeries
This is a response-adaptive (RAR) prospective randomized study with a long-term follow-up and the aim of this clinical study is to measure with qualitative and quantitative indicators the changes in cosmetic results, quality of…
- Conditions
- Breast Cancer, Mastectomy; Lymphedema, Quality of Life, Patient Satisfaction
- Trial name
- NCT04345081
- Testing
- Skin Reducing Nipple Sparing Mastectomy and Implant Based Breast Reconstruction, Skin- Sparing Mastectomy and Implant- Based Breast Reconstructive Surgery
- Where
- Hungary
- Volunteers
- 110 people
- Sponsor
- National Institute of Oncology, Hungary
Heart Failure
Exercise Training in Heart Failure: Changes in Cardiac Structure and Function
This is a research study being conducted to better understand the impact of exercise training on changes on the structure and function of the heart.
- Trial name
- NCT02275819
- Testing
- Exercise
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- VA Office of Research and Development
Behavior, Health
Parent-Child Memory Study: Improving Future Thinking Among Mothers
Parents of children from impoverished communities are disproportionately more likely to engage in harsh physical discipline, which can lead to serious clinical outcomes, including suicidal ideation and attempts.
- Trial name
- NCT06145919
- Testing
- Episodic Future Thinking (EFT), Episodic Recent Thinking (ERT)
- Where
- United States
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Henry Ford Health System
Depression
To Demonstrate the Relative Bioavailability of Cyclobenzaprine HCl Tablets
To demonstrate the relative bioavailability of Cyclobenzaprine HCl tablets.
- Trial name
- NCT00913419
- Testing
- Cyclobenzaprine HCl Tablets 10 mg, Cord Laboratories, Cyclobenzaprine HCl Tablets 10 mg, Merck Sharp & Dohme
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Sandoz
Kidney Diseases, Kidney Transplant Failure and Rejection
The Microbiota in Kidney Donation and Transplantation
The human gastrointestinal tract harbours ~40 trillion microbial cells, far outnumbering the cell number, and therefore the genetic content of its host.
- Conditions
- Kidney Diseases, Kidney Transplant Failure and Rejection, Urinary Tract Infections
- Trial name
- NCT04388930
- Testing
- Pre-operative assessment - blood, urine, & faecal sample, Post-operative day 3 assessment - blood, urine, & faecal sample, Post-operative week 4-6 assessment - blood, urine, & faecal sample
- Where
- United Kingdom
- Volunteers
- 130 people
- Sponsor
- Royal Free Hospital NHS Foundation Trust
Low Back Pain
The Effects of Telerehabilitation and Supervised Stabilization Exercises in Individuals With Nonspecific Chronic Low Back Pain
This study aims to investigate the effects of telerehabilitation and supervised stabilization exercises on pain, functionality, kinesophobia and quality of life in individuals with non-specific chronic low back pain.
- Trial name
- NCT04759430
- Testing
- Supervised Group, Telerehabilitation group
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people
- Sponsor
- Bahçeşehir University
Mild Cognitive Impairment
Effects of an Empowerment-based Psycho-behavioral Program on Persons With Mild Cognitive Impairment
This study aims to evaluate the effects of a 13-week empowerment-based psycho-behavioral program to improve neuropsychiatric symptoms, cognitive functions, and health-related quality of life among persons with mild cognitive…
- Trial name
- NCT04723667
- Testing
- 13-week multimodal intervention, 5-week health education programme
- Where
- 2 sites in Hong Kong
- Volunteers
- 171 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Schizophrenia, Schizoaffective Disorder
Effect of Varenicline on Cognitive Function in Cigarette Smokers With Schizophrenia
Smokers with schizophrenia have more difficulties quitting smoking than smokers without a mental disorder. Varenicline (Champix) is a new stop smoking medication with a unique mechanism of action.
- Trial name
- NCT01093365
- Testing
- Varenicline
- Where
- Canada
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Centre for Addiction and Mental Health
Anxiety, Depression
Using Neuroimaging to Understand Children's Mental Health and Treatment Outcomes
The study will compare the impact of Child STEPs versus usual school-based therapy on neural and companion behavioral measures of self-regulation.
- Conditions
- Anxiety, Depression, Trauma, Behavior Problems
- Trial name
- NCT03112265
- Testing
- Modular Approach to Therapy for Children with Anxiety, Depression, Trauma, and Conduct Problems, Monitoring and Feedback System, Treatment as usual
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Harvard University
Headache, Migraine, Migraine
Mind and Body Approaches to Pain Reduction in Youth With Migraine
The overarching objective of this protocol is to identify and understand the neural and pain processing mechanisms by which youth with migraine improve in response to preventive treatment.
- Conditions
- Headache, Migraine, Migraine, Migraine Disorders, Headache
- Trial name
- NCT03472092
- Testing
- Cognitive Behavioral Therapy (CBT), Amitriptyline, Biofeedback-Assisted Relaxation Training (BART)
- Where
- United States
- Volunteers
- 132 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Depression and Suicide Ideation
Development and Feasibility of a Metaverse-based Blended Online Intervention to Prevent Employees' Depression
The goal of this feasibility study is to develop a new metaverse-based blended online intervention using an online program and coaching via metaverse to prevent depression among Generation MZ Employees in South Korea.
- Trial name
- NCT06426342
- Testing
- metaverse-based blended online intervention
- Where
- South Korea
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Ewha Womans University
Obstructive Sleep Apnea, Comorbid Insomnia and Sleep Apnea
Does the Timing of Insomnia Therapy (CBT-i) Impact the Usage and Compliance of Upper Airway Stimulation (UAS) Treatment of Obstructive Sleep Apnea (OSA)
Obstructive sleep apnea, or OSA, affects over 1 billion adults worldwide. OSA is one of many sleep disorders. Individuals can suffer from more than one sleep disorder at a time.
- Conditions
- Obstructive Sleep Apnea, Comorbid Insomnia and Sleep Apnea, Insomnia
- Trial name
- CBT-i and UAS (NCT07838870)
- Testing
- Digital Cognitive Behavioral Therapy (CBT-i)-COAST
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Thomas Kaffenberger
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.