Clinical trials: Confusion Postoperative
Postoperative Pain, Postoperative Delirium
Multimodal Versus Opioid aNalgesia in carDiAc Surgery
To compare standard "Fentanyl - Tramadol - Paracetamol - Oxycodone" regimen to a multimodal painmanagement "pregabalin- minimal fentanyl-ketamine-lidocain-dexmedetomidine- paracetamol" to determine which therapy provides the most…
- Trial name
- MONDAY (NCT04987372)
- Testing
- Dexmedetomidine
- Where
- Belgium
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University Hospital, Ghent
Postoperative Delirium
Dexmetomedine for Post Operative Delirium in Elderly Patients Undergoing Elective Total Knee Replacement Under Spinal Anesthesia
Postoperative delirium is a geriatric syndrome occurring after anesthesia and surgery which manifests as acute alterations in mental status, involving changes in cognition, attention, and levels of consciousness that tend to…
- Trial name
- NCT05707741
- Testing
- dexmetomedine infusion
- Where
- Egypt
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Menoufia University
Remimazolam, Emergence Delirium
Remimazolam for Emergence Delirium Prevention in Patients Undergoing Rhinoseptoplasty, FESS or Septoplasty
The aim of this research is to confirm the effectiveness of remimazolam in preventing delirium during recovery from anesthesia in adult patients who have undergone one of the rhinological surgeries (septoplasty, rhinoseptoplasty…
- Conditions
- Remimazolam, Emergence Delirium, Rhinoplasty
- Trial name
- NCT06398275
- Testing
- Remimazolam 20 MG Injection [Byfavo], NaCl 0.9%
- Where
- Croatia
- Volunteers
- 80 people
- Sponsor
- University Hospital of Split
Delirium
The Effect of Melatonin on Postoperative Delirium in Elderly ICU Patients
Delirium in older patients is associated with increased mortality and health care costs. And delirium is frequent in intensive care unit (ICU).
- Trial name
- NCT02588742
- Testing
- Melatonin
- Where
- South Korea
- Volunteers
- 3 people
- Sponsor
- Yonsei University
Postoperative Delirium, Postoperative Cognitive Dysfunction
fMRI Connectivity in Fracture Hip Patients
The long-term goal of this study is to evaluate cognitive function preoperatively and develop techniques of intervention in the perioperative period which would optimize brain function and functional recovery following surgery.
- Trial name
- NCT02997930
- Testing
- fMRI, Montreal Cognitive Assessment (MoCA), Digital Clock Drawing Test Command and Copy
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- University of Florida
Femoral Neck Fractures, Postoperative Complications
Postoperative Recovery in Elderly Patients Undergoing Hip Hemi-arthroplasty
Hip fractures incidence grows rapidly with the aging of the population. After indicated surgical treatment, hip fracture patients experience high rates of postoperative complications, postoperative delirium (PD), postoperative…
- Conditions
- Femoral Neck Fractures, Postoperative Complications, Inflammatory Response, Postoperative Delirium
- Trial name
- NCT01934049
- Testing
- hip arthroplasty, Total Intravenous Anesthesia and Peripheral nerve blocks
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Chinese PLA General Hospital
Postoperative Delirium, Postoperative Pain
Effect of Electroencephalography Guided General Anesthesia on Postoperative Delirium in Children
Participants aged 4-10 years (92 patients), who came to the Hospital Operating Room at the University Faculty of Dentistry with an indication for dental treatment under general anesthesia due to lack of cooperation, will be…
- Trial name
- NCT06400706
- Testing
- EEG guided general anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Aydin Adnan Menderes University
Fasting
The Effects of Carbohydrate-electrolyte Solution on Metabolic Responses in Paediatric Patients
The aim of this study is to evaluate the effects of oral administration of carbohydrate-electrolyte-containing fluid, compared to standard clear fluid during preoperative fasting on metabolic responses, preoperative anxiety and…
- Trial name
- NCT05729100
- Testing
- Oral carbohydrate-electrolyte solution, Control
- Where
- Indonesia
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Delirium in Old Age, Anaesthetic
Impact of Propofol Versus Sevoflurane on Incidence of Postoperative Delirium in Elderly Patients After Spine Surgery
Postoperative delirium in older adults is a common and costly complication after surgery. Propofol and sevoflurane are commonly used anesthetics to maintain sedation during spine surgery, and have different sedative and…
- Trial name
- NCT05158998
- Testing
- propofol infusion, sevoflurane inhalation
- Where
- 2 sites in China
- Volunteers
- 298 people
- Sponsor
- Qianfoshan Hospital
Cohort Studies
The Impact of Preoperative Depression on Postoperative Delirium in Elderly Chinese Patients: A Retrospective Multicenter Observational Study
This study is a retrospective analysis of a large-scale multicentre prospective cohort study that investigates the impact of preoperative depression on the incidence of postoperative delirium among elderly Chinese patients…
- Trial name
- NCT07744282
- Volunteers
- 8,000 people
- Sponsor
- Chinese PLA General Hospital
Emergence Agitation, Vocal Cord Polyps
Intranasal Dexmedetomidine Combined With Esketamine for Emergence Quality After Suspension Laryngoscopy
This is a single-center, prospective, single-blinded, randomized controlled trial conducted at The First Hospital of Jilin University.
- Trial name
- NCT07880938
- Testing
- Dexmedetomidin, Esketamine
- Where
- China
- Volunteers
- 134 people
- Sponsor
- The First Hospital of Jilin University
Postoperative Delirium
The Comparison of Incidence and Risk Factors of Postoperative Delirium in Elderly Patients After Lower Extremity Surgery
The aim of this study is to compare the risk factors and the incidence of delirium following orthopedic surgery under the general or regional anesthesia in elderly patients.
- Trial name
- NCT02360982
- Testing
- propofol and esmeron(rokuronyum), marcaine and fentanyl
- Volunteers
- 120 people
- Sponsor
- Cukurova University
Postoperative Delirium
Perioperative Dexmedetomidine on Postoperative Delirium in Patients With Brain Tumors
Neurosurgery is a risk factor for delirium. Dexmedetomidine might reduce delirium by reducing neuroinflammation, improving postoperative analgesia and sleep quality.
- Trial name
- NCT06164314
- Testing
- Dexmedetomidine
- Where
- China
- Volunteers
- 366 people
- Sponsor
- Beijing Tiantan Hospital
Donor Site Complication, Delirium
s100β, NSE n GFAP in Living Donor Hepatectomy and Delirium
The post-operative delirium picture is a serious and common complication seen after any major surgery, including hepatic resection.
- Conditions
- Donor Site Complication, Delirium, Uremic Encephalopathy, Neurologic Manifestations
- Trial name
- NCT04422925
- Testing
- Living Donor Hepatectomy
- Where
- Turkey (Türkiye)
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Akdeniz University
Hearing Loss, Hearing Loss, Age-Related
Sight and Hearing Investigation Into Effects on Delirium
The goal of this observational study is to learn about sensory loss in hospital patients with delirium. The main questions it aims to answer are: Are hearing and vision loss related to increased risk of having delirium? Do…
- Conditions
- Hearing Loss, Hearing Loss, Age-Related, Hearing Disability, Delirium
- Trial name
- SHIELD (NCT06176625)
- Testing
- Communication Signage, Amplifier Use
- Where
- United States
- Volunteers
- 1,543 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Neurosurgery, Delirium - Postoperative
Electroencephalogram Predicts Post-operative Delirium
The goal of this observational study is to investigate the predictive value of sub-hairline electroencephalography (EEG) during anesthesia recovery for postoperative delirium (POD).
- Conditions
- Neurosurgery, Delirium - Postoperative, Brain Tumor Adult
- Trial name
- EPOD (NCT06894238)
- Testing
- Sub-hairline EEG Monitoring
- Where
- 2 sites in China
- Volunteers
- 137 people
- Sponsor
- Beijing Sanbo Brain Hospital
Postanesthetic Excitement, Cesarean Section
Dexmedetomidine Compared to Ondansetron for Postanaesthetic Shivering in Patients Undergoing a Cesarean Section
Evaluate the efficiency of management with intravenous dexmedetomidine compared to intravenous ondansetron to achieve the disappearance of post-anesthetic shivering in a shorter time in the obstetric patient undergoing cesarean…
- Trial name
- NCT06289335
- Testing
- saline solution
- Where
- Mexico
- Volunteers
- 40 people
- Sponsor
- Hospital Central "Dr. Ignacio Morones Prieto"
Delirium, Postoperative Cognitive Deficit (POCD)
Neuroprotection With Dexmedetomidine in Patients Undergoing Elective Cardiac or Abdominal Surgery (Neuprodex)
The drug Dexmedetomidine will be investigated in 72 patients (men and women) undergoing elective cardiac or abdominal surgery. The study medication will be administered perioperatively by intravenous infusion continuously (at the…
- Trial name
- NCT02096068
- Testing
- Dexmedetomidine (Dexdor®), 0.9% Sodium Chloride
- Where
- Germany
- Volunteers
- 78 people
- Sponsor
- Claudia Spies
Postoperative Delirium (POD)
Perioperative Dezocine Administration and Postoperative Delirium in Elderly Cardiac Surgery Patients
Postoperative delirium (POD) is a common complication in elderly patients undergoing cardiac surgery and is associated with prolonged hospitalization, increased morbidity, and poor recovery.
- Trial name
- NCT07768150
- Testing
- Dezocine, Normal Saline (NS)
- Where
- 2 sites in China
- Volunteers
- 640 people
- Sponsor
- Chinese Academy of Medical Sciences, Fuwai Hospital
Emergence Delirium
The Effect of Binaural Sound on the Occurrence of Emergence Delirium in Children Undergoing Strabismus Surgery
The hypothesis of this study is that providing continuous binaural beats with a phase difference in alpha frequency during anesthesia can reduce the incidence of emergence agitation in pediatric patients.
- Trial name
- NCT05883280
- Testing
- Binaural beats
- Where
- South Korea
- Volunteers
- 74 people
- Sponsor
- Seoul National University Hospital