Clinical trials: Confusion Postoperative
Delirium
Different Doses of Sevoflurane During Induction of Anesthesia on Emergence Delirium in Children
The investigators aim to reduce the incidence of emergence delirium in children aged 2-7 years old by using two different doses of sevoflurane during inhalatory induction of anesthesia.
- Trial name
- NCT02707016
- Testing
- Sevoflurane 8%, Sevoflurane 5%
- Where
- Chile
- Volunteers
- 80 people
- Sponsor
- Pontificia Universidad Catolica de Chile
Nasal Surgery
Performance of EEG During Emergence Agitation in Nasal Surgery.
The purpose of the study is to evaluate the relationship between perioperative electroencephalogram and emergence agitation in the nasal surgery.
- Trial name
- NCT05654311
- Testing
- Nasal surgery
- Where
- South Korea
- Volunteers
- 55 people
- Sponsor
- Gangnam Severance Hospital
Neuromuscular Blockade, Delayed Emergence From Anesthesia
Sugammadex Timing and Recovery Profile in Pediatric Adenotonsillectomy
Sugammadex is routinely used to reverse rocuronium-induced neuromuscular blockade in children. In clinical practice, it is given either while the child is still deeply anesthetized or after the anesthetic has lightened.
- Conditions
- Neuromuscular Blockade, Delayed Emergence From Anesthesia, Emergence Agitation
- Trial name
- SUGA-PED (NCT07902193)
- Where
- Turkey (Türkiye)
- Volunteers
- 140 people
- Sponsor
- Namik Kemal University
Emergence Delirium, Anesthesia, Child
Melatonin vs Midazolam in Children Undergoing Tonsillectomy
Used as a premedication to decrease anxiety (Caumo et al., 2007). Midazolam, though has several drawbacks (McCann and Kain, 2001). Hence, an alternative premedication to midazolam will definitely have a widespread appeal.
- Conditions
- Emergence Delirium, Anesthesia, Child, Anxiety, Midazolam Premedication
- Trial name
- NCT07336095
- Testing
- Melatonin group, Midazolam group, Control group
- Volunteers
- 195 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Delirium, Postoperative, Delirium in Old Age
The SCOPE Trial: Sleep, Cognition, and Pain Bundle vs. ERAS-cardiac for Postoperative Delirium
Sleep disturbances, cognitive reserve, and continuing pain and inflammation are other risk factors contributing to delirium (confusion and agitation) and neurocognitive decline (in the long term) following heart surgery.
- Trial name
- SCOPE (NCT06721819)
- Testing
- Sleep Hygiene, Brain Game, and IV Acetaminophen Intervention, Control
- Where
- 3 sites in United States
- Volunteers
- 406 people
- Sponsor
- Beth Israel Deaconess Medical Center
Postoperative Delirium, Postoperative Cognitive Dysfunction
The Impact of Repetitive Transcranial Magnetic Stimulation on the Prognosis of Elderly Surgical Patients
Exploring the effects of repeated transcranial magnetic stimulation (rTMS) during the perioperative period on the incidence of postoperative delirium, postoperative cognitive dysfunction, and chronic postoperative pain in elderly…
- Conditions
- Postoperative Delirium, Postoperative Cognitive Dysfunction, Chronic Post-surgical Pain
- Trial name
- NCT06392919
- Testing
- Repetitive Transcranial Magnetic Stimulation
- Where
- China
- Volunteers
- 352 people
- Sponsor
- Affiliated Hospital of Nantong University
Anesthesia Recovery Period, Delirium, Dementia, Cognitive Disorders
Postanesthesia Cognitive Recovery and Neuropsychologic Complications
The study proposes to analyze the difference in the rapidity of the recovery of post operative cognition immediately after extubation and 20, 40 and 60 minutes post extubation and neuropsychological complications (delirium) after…
- Conditions
- Anesthesia Recovery Period, Delirium, Dementia, Cognitive Disorders, Neurobehavioural Manifestation, Mental Competency
- Trial name
- NCT00507195
- Testing
- Hypnotics: propofol, sevoflurane, desflurane,desflurane,midazolam
- Where
- Italy
- Volunteers
- 1,200 people
- Sponsor
- University of Roma La Sapienza
Postoperative Delirium, Elderly Patient
Automated Administration of Intravenous Compared With Inhalatory Anesthesia on the Occurrence of Postoperative Delirium
The intravenous administration of anesthetic agents by a controller automatically-guided by an index of cerebral activity (i.e. the bispectral index) decreases the incidence of postoperative delirium, compared with an…
- Conditions
- Postoperative Delirium, Elderly Patient, General Anesthetic Drug Adverse Reaction
- Trial name
- AG-DPO (NCT03705728)
- Testing
- Propofol, Sevoflurane, Remifentanil automatic
- Where
- France
- Volunteers
- 1,000 people
- Sponsor
- Centre Clinical, France
Femoral Neck Fracture
The Effect of Periarticular Multi-Drug Regimen on Pain After Partial Hip Replacement
This prospective randomized study aims to evaluate the effectiveness of periarticular multi-drug regimen injection on the relief of pain in patients undergoing partial hip replacement.
- Trial name
- NCT01112436
- Testing
- periarticular injection of multidrug regimen, none of medication preoperatively and intraoperatively
- Where
- South Korea
- Volunteers
- 258 people
- Sponsor
- Chung-Ang University Hospital
Emergence Agitation
Effect of Induction Method in Post Operative Agitation
To compare the effect of two different induction method; mask ventilation and intravenous cannulation on emergence agitation on pediatric adenotonsillectomy
- Trial name
- NCT03252405
- Testing
- mask ventilation, intravenous cannulation
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Ahi Evran University Education and Research Hospital
Delirium on Emergence
Ketofol for Preventing Postoperative Delirium in Elderly Patients
Delirium is a cognitive disturbance characterized by acute and fluctuating impairment in attention and awareness. Although its incidence in the general surgical population is 2-3%, it has been reported to occur in up to 10-80% of…
- Trial name
- NCT04816162
- Testing
- ketofol, dexmedetomidine, normal saline
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Zagazig University
Emergence Delirium, Emergence Agitation
Postoperative Neurocognitive Dysfunction: Is There Any Place for Emergency Agitation: A Prospective Cohort Trial
Perioperative neurocognitive disorders (PND) have been studying by clinicians, particularly by anesthesiologists, pretty long, however the most inspiring advancements were achieved during the last few decades.
- Conditions
- Emergence Delirium, Emergence Agitation, Postoperative Delirium
- Trial name
- PoD (NCT04820595)
- Testing
- RASS, CAM-ICU
- Where
- 2 sites in Russia
- Volunteers
- 200 people
- Sponsor
- Negovsky Reanimatology Research Institute
Delirium
Acetylcholinesterase in Postoperative Delirium
The level of acetylcholinesterase is suspected to correlate with postoperative delirium. The investigators therefore score patients once preoperatively and twice postoperatively with the german version of the delirium-score…
- Trial name
- NCT02315846
- Where
- Germany
- Volunteers
- 120 people
- Sponsor
- Heidelberg University
Cognitive Disorders, Delirium
The Impact of Ketamine on Postoperative Cognitive Dysfunction, Delirium, and Renal Dysfunction
Ketamine is a commonly used anesthetic medication which is used for induction of anesthesia as well as as an analgesic. It has been shown to have anti-inflammatory properties which may decrease post-operative complications…
- Conditions
- Cognitive Disorders, Delirium, Acute Kidney Injury
- Trial name
- NCT02554253
- Testing
- Ketamine, Propofol
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- Mayo Clinic
Postoperative Delirium
Dexmedetomidine vs Midazolam in Coronary Artery By-pass Surgery
The aim is to compare the incidence of postoperative delirium following coronary artery bypass grafting (CABG) between patients receiving dexmedetomidine and those receiving midazolam infusions.
- Trial name
- NCT07411794
- Testing
- Intravenous Dexmedetomidine infusion + Standard Anesthesia, intravenous midazolam infusion + Standard anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Cumhuriyet University
Delirium, Awakening, Post-Anesthesia Delayed
Validation and Reliability of the Turkish 4AT Scale for Post-Anesthesia Awakening Delirium
Background: Delirium is a common and serious condition in hospitalized patients that often leads to extended hospital stays and increased healthcare costs. Accurate and timely detection is essential for optimal patient outcome.
- Conditions
- Delirium, Awakening, Post-Anesthesia Delayed, Delirium, Postoperative, Nurse's Role
- Trial name
- NCT06187389
- Testing
- 1 Grups
- Where
- Turkey (Türkiye)
- Volunteers
- 188 people, healthy volunteers welcome
- Sponsor
- Kilis 7 Aralik University
Postoperative Delirium, Aortic Valve Stenosis
Assessing the Incidence of Postoperative Delirium Following Aortic Valve Replacement
Our primary aim in this observational study is to identify the incidence of POD in the first five postoperative days by using the 3-minute Diagnostic confusion assessment method (3D-CAM), the derived version for intensive care…
- Trial name
- IPOD-AV (NCT03950440)
- Where
- Belgium
- Volunteers
- 250 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven