Clinical trials: Confusional State
Postoperative Delirium, Postoperative Pain
Effect of Electroencephalography Guided General Anesthesia on Postoperative Delirium in Children
Participants aged 4-10 years (92 patients), who came to the Hospital Operating Room at the University Faculty of Dentistry with an indication for dental treatment under general anesthesia due to lack of cooperation, will be…
- Trial name
- NCT06400706
- Testing
- EEG guided general anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Aydin Adnan Menderes University
Postoperative Delirium
Dexmedetomidine in Reducing Incidence of Emergence Agitation After Nasal Surgery
Various pharmacological interventions have been attempted previously to prevent postoperative EA with variable results. These include use of opioids, propofol, midazolam, ketamine, magnesium and alpha-2 agonists like clonidine…
- Trial name
- NCT05634148
- Testing
- Dexmedetomidine
- Where
- Saudi Arabia
- Volunteers
- 42 people
- Sponsor
- Security Forces Hospital
PREOPERATIVE SLEEP QUALITY ON POSTOPERATIVE DELIRIUM
Preoperative Sleep Quality and Postoperative Delirium
Background: Delirium is a neurocognitive illness that has lately been connected to sleep difficulties. It is a stressful condition. is still not fully understood.
- Trial name
- NCT06273358
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people
- Sponsor
- Konya City Hospital
Postoperative Delirium
Prevention of Postoperative Delirium in Elderly Patients
Prevention of Postoperative Delirium in the care of Elderly Patients. A Monocentric, Prospective Intervention Study With the Question of Whether the Incidence, Length and Severity of Postoperative Delirium Can be Reduced by…
- Trial name
- PODproject (NCT06248684)
- Testing
- standardized prevention and therapy measures
- Volunteers
- 15,000 people
- Sponsor
- Technical University of Munich
Delirium
Impact of Various Sedation Regimens on the Incidence of Delirium
Sedation drugs that are commonly used in ICU in treatment of ARDS, includes propofol, midazolam and dexmedetomidine . Among these, both dexmedetomidine and propofol have been reported to be used together with midazolam in ICU and…
- Trial name
- NCT02117726
- Testing
- Dexmedetomidine,midazolam, Propofol,midazolam
- Where
- 7 sites in China
- Volunteers
- 320 people
- Sponsor
- Shandong Provincial Hospital
Critical Illness
PICU Up!: A Pilot Stepped-wedge Trial of a Multicomponent Early Mobility Intervention for Critically Ill Children
Recent decreases in Pediatric Intensive Care Unit (PICU) mortality rates have been offset by increased morbidity and length of stay for vulnerable young patients.
- Trial name
- PICU Up! (NCT03860168)
- Testing
- PICU Up!
- Where
- United States
- Volunteers
- 2,500 people
- Sponsor
- Johns Hopkins University
Delirium, Agitation
The Effectiveness of Acupuncture for Complications in Critically Ill Patients
Introduction: Intensive care unit (ICU) is a special department in the health care facility. Although with high development of modern medicine nowadays, the average mortality rate in ICU is still around 7 to 20 %.
- Conditions
- Delirium, Agitation, Arrhythmia, Feeding Intolerance
- Trial name
- NCT04950738
- Testing
- pess tack acupuncture
- Volunteers
- 80 people
- Sponsor
- China Medical University Hospital
Postoperative Delirium
Effect of Electroacupuncture on the Incidence of Postoperative Delirium in Elderly Patients Undergoing the Major Surgery
1. Title: Effect of electroacupuncture on the incidence of postoperative delirium in elderly patients undergoing the major surgery. 2. Research center: Multicenter 3.
- Trial name
- NCT03606941
- Testing
- electroacupuncture treatment
- Where
- China
- Volunteers
- 1,100 people
- Sponsor
- Tianjin Nankai Hospital
Ophthalmology
Study on the Effect of Eye-covering Pretreatment on Acute Delirium After General Anesthesia in Pre-school Aged Children
Participants (preschool children), because their cognitive ability and anti pressure ability are obviously weaker than adults, most of the children who have this kind of operation and anesthesia stressors will have perioperative…
- Trial name
- NCT04973150
- Testing
- To explore whether pretreatment with eye covering can reduce the incidence of acute delirium and the score of delirium after general anesthesia in ophthalmology pre-age children.
- Where
- China
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Delirium
MusiC to Prevent deliriUm During neuroSurgerY
Rationale: Delirium is a common and severe complication after neurosurgical procedures. Music before, during and after surgical procedures has proven its effectiveness in reducing pain, anxiety, stress and opioid medication in…
- Trial name
- MUSYC (NCT04649450)
- Testing
- Music
- Where
- Netherlands
- Volunteers
- 189 people
- Sponsor
- Erasmus Medical Center
Older Patients, Orthopedic Surgery
Buccal Acupuncture for Delirium Treatment in Older Patients Recovering From Orthopedic Surgery
This study is designed to test the hypothesis that, for older orthopedic patients who developed postoperative delirium, combining buccal acupuncture with routine care will shorten delirium duration and relieve delirium severity.
- Conditions
- Older Patients, Orthopedic Surgery, Postoperative Delirium, Acupuncture
- Trial name
- NCT05537155
- Testing
- Buccal acupuncture in addition to routine care, Routine care
- Sponsor
- Peking University First Hospital
Postoperative Delirium
Postoperative Delirium: EEG Markers of Sleep and Wakefulness
Postoperative delirium is a condition in which patients develop temporary difficulties in maintaining attention and thinking clearly. These new problems can appear after surgery and change throughout the day.
- Trial name
- NCT03291626
- Where
- United States
- Volunteers
- 234 people
- Sponsor
- Washington University School of Medicine
Postoperative Delirium (POD), Gynecologic Cancers
Immunonutrition and Neuromonitoring for Postoperative Delirium in Gynecologic Oncology
Early postoperative delirium (POD) is a common and distressing neuropsychiatric complication frequently observed in elderly patients undergoing major surgical interventions, including radical and cytoreductive gynecologic…
- Conditions
- Postoperative Delirium (POD), Gynecologic Cancers, Malnutitrion
- Trial name
- NCT07877285
- Testing
- Preoperative Immunonutritional Scoring and Intraoperative Neuromonitoring
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Elazıg Fethi Sekin Sehir Hastanesi
Emergence Delirium, Anesthesia, Preschool Age Children
Influence of Intraoperative Auditory Intervention on Emergence Delirium in Preschoolers: A Randomised Controlled Clinical Trial
Emergence delirium (ED), characterized by disorientation and altered cognitive behavior, is a common postoperative complication in pediatric surgery.
- Conditions
- Emergence Delirium, Anesthesia, Preschool Age Children, Emergence Agitation
- Trial name
- NCT07630922
- Testing
- Classical Music Group, Mother's Heartbeat Recording Group, Mother's Lullaby Recording Group
- Where
- China
- Volunteers
- 96 people
- Sponsor
- Henan Provincial People's Hospital
Postoperative Delirium, Sevoflurane
Intraoperative EEG Monitoring and Postoperative Delirium in Elderly Patients With Sevoflurane Anesthesia
Delirium is an acute onset of attentional and cognitive impairment. BIS guided anesthesia can reduce the incidence of postoperative delirium.
- Conditions
- Postoperative Delirium, Sevoflurane, Electroencephalogram
- Trial name
- NCT04292561
- Testing
- Low MAC, High MAC
- Where
- China
- Volunteers
- 460 people
- Sponsor
- The First Affiliated Hospital of Anhui Medical University
Post-operative Delirium
Benzodiazepine-free Anesthetic for Reduction of Delirium (B-Free)
The purpose of this two-centre pilot research study is to establish the feasibility of conducting a full trial that seeks to determine if a cardiac anesthesia policy that uses alternatives to benzodiazepine medications is better…
- Trial name
- B-Free (NCT03053869)
- Testing
- Benzodiazepine - limited use strategy, Benzodiazepine - Ad libitum strategy
- Where
- 2 sites in Canada
- Volunteers
- 480 people
- Sponsor
- McMaster University
Postoperative Delirium
Cerebral Blood Supply During Cardiopulmonary Bypass
Postoperative delirium is an acute and fluctuating state of confusion and disorientation with an incidence of 25-70% after cardiac surgery.
- Trial name
- NCT03117712
- Testing
- Delirium Scores, Carotis duplex sonography, TCD for detection of HITS
- Where
- Austria
- Volunteers
- 40 people
- Sponsor
- Medical University of Vienna
Lower Extremity Problem, Delirium
Intraoperative Sedatives and Postoperative Deilirium
Delirium occurs commonly in elderly patients. Its incidence after orthopedic surgery has been reported to be 5-61%. Delirium is classified into three sub-types: Hypoactive, hyperactive, and mixed.
- Conditions
- Lower Extremity Problem, Delirium, Propofol, Dexmedetomidine
- Trial name
- NCT03251651
- Testing
- Propofol, Dexmedetomidine
- Where
- South Korea
- Volunteers
- 748 people
- Sponsor
- Seoul National University Bundang Hospital
General Anesthesia
The Relationship Between the SPI and the Postop ED
Surgical plethysmography index (SPI) is a device that can noninvasively monitor the balance between the nociception and ant-nociception using pulse photoplethysmographic amplitude (PPGA) and heart rate obtained through an oxygen…
- Trial name
- SPI_ED (NCT03328910)
- Testing
- SPI monitor (GE Healthcare, Helsinki, Finland)
- Where
- South Korea
- Sponsor
- Daegu Catholic University Medical Center
Delirium, Cognitive Impairment
Illuminating Neuropsychological Dysfunction and Systemic Inflammatory Mechanisms Gleaned After Hospitalization in Trauma-ICU Study
Cognitive skills are essential to live independently, manage finances, maintain employment, and function in society. Loss of these cognitive skills puts a tremendous burden on society as seen with dementias, Alzheimer's disease…
- Conditions
- Delirium, Cognitive Impairment, Alzheimer; Early Onset, Trauma
- Trial name
- INSIGHT-ICU (NCT03098459)
- Testing
- Non-interventional observational prospective cohort study
- Where
- United States
- Volunteers
- 432 people
- Sponsor
- Vanderbilt University Medical Center