Clinical trials: Congenital Aniridia
Aniridia
Correlation of Gene Abnormalities and Clinical Manifestations of Aniridia
This study will examine specific gene changes in patients with aniridia, a disease in which the iris (colored part of the eye) is absent or partially absent, and will correlate the changes with clinical manifestations of the…
- Trial name
- NCT00265590
- Where
- 3 sites in United States
- Volunteers
- 100 people
- Sponsor
- National Eye Institute (NEI)
Aniridia
Proteomic Study of Tears From Patients With a PAX6 Mutation
This is a single-center prospective pilot study involving the ophthalmology and medical genetics departments of the Montpellier University Hospital, and the proteomics platform of the Montpellier University Hospital.
- Trial name
- PLAPAX6 (NCT05562115)
- Testing
- Tear collection
- Where
- France
- Volunteers
- 5 people
- Sponsor
- University Hospital, Montpellier
Eye Abnormalities
Modeling Ocular Developmental Diseases From 3D Cultures of Optic Vesicle Organoids Derived From hiPSCs of Patients With Ocular Malformations
Ocular morphogenesis is a complex process starting as early as the 4th week of embryonic life, involving interactions between varioustissues of different origin and conserved genes.
- Trial name
- OrganoEye (NCT06408701)
- Testing
- Blood sampling
- Where
- 2 sites in France
- Volunteers
- 20 people
- Sponsor
- University Hospital, Toulouse
Aniridia, Eye Abnormality
Abnormalities of the Eye's Anterior Chamber, Iris, Cornea and Lens
This study will investigate congenital or developmental eye abnormalities that affect the iris, cornea and lens, and are usually accompanied by elevated pressure within the eye.
- Conditions
- Aniridia, Eye Abnormality, Ocular Hypertension, Open Angle Glaucoma
- Trial name
- NCT00001161
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- National Eye Institute (NEI)