Clinical trials: Congenital Ichthyosis
Congenital Ichthyosis
A Vehicle Controlled Study to Evaluate Safety and Efficacy of Topical TMB-001 for Treatment of Congenital Ichthyosis
The purpose of this study is to investigate the efficacy and safety of two concentrations of topically applied ointment formulation of isotretinoin called TMB-001 (0.05% and 0.1% isotretinoin) in subjects 9 years of age and older…
- Trial name
- NCT04154293
- Testing
- Isotretinoin, Vehicle
- Where
- 11 sites in United States, Australia
- Volunteers
- 34 people
- Sponsor
- LEO Pharma
Congenital Ichthyosis
A Safety and Tolerability Study of Topical PAT-001 in Congenital Ichthyosis
Congenital ichthyosis (CI) is a large, heterogeneous family of inherited skin disorders of cornification resulting from an abnormality of skin keratinization, such as scaling and thickening of the skin.
- Trial name
- NCT02864082
- Testing
- PAT-001, 0.1%, PAT-001, 0.2%, Vehicle for PAT-001 0.1%
- Where
- 5 sites in United States
- Volunteers
- 19 people
- Sponsor
- Patagonia Pharmaceuticals, LLC
TGM-1 Related Autosomal Recessive Congenital Ichthyosis
Topical KB105 Gene Therapy for the Treatment of TGM1-deficient Autosomal Recessive Congenital Ichthyosis (ARCI)
This study is an intra-patient comparison of KB105 and placebo-administered Target Areas. The primary objectives of this study are to evaluate safety and Investigator Global Assessment (IGA) scale improvement of topically…
- Trial name
- NCT04047732
- Testing
- KB105
- Where
- 2 sites in United States
- Volunteers
- 6 people
- Sponsor
- Krystal Biotech, Inc.