Clinical trials: Congestion, Nasal
Cough, Sore Throat
A Study to Evaluate the Efficacy and Safety of IV Peramivir in Addition to Standard of Care Compared to Standard of Care Alone in Adults and Adolescents Who Are Hospitalized Due to Influenza
A Phase 3, multicenter, randomized, double-blind, controlled study to evaluate the efficacy and safety of peramivir administered intravenously in addition to standard of care compared to standard of care alone in adults and…
- Conditions
- Cough, Sore Throat, Nasal Congestion, Headache
- Trial name
- NCT00958776
- Testing
- Peramivir+SOC
- Where
- 196 sites in United States, Argentina and 21 more
- Volunteers
- 405 people
- Sponsor
- BioCryst Pharmaceuticals
Allergic Rhinitis, Allergic Conjunctivitis
Demonstration of Equivalence and Early Onset of a Novel Anti-allergic Nasal Spray Compared to Marketed Nasal Spray
Intranasal corticosteroids are accepted as safe and effective first-line therapy for allergic rhinitis, especially in treatment of persistent symptoms.
- Conditions
- Allergic Rhinitis, Allergic Conjunctivitis, Hayfever
- Trial name
- NCT03755557
- Testing
- Rhinocort, Budesolv
- Where
- Austria
- Volunteers
- 82 people
- Sponsor
- Marinomed Biotech AG
Nasal Congestion, Common Cold
Post-market Clinical Follow-up Study of an Isotonic Saline Solution for the Relief of Nasal Congestion in Infants and Toddlers
The goal of this observational post-market clinical follow-up study is to evaluate the safety and performance of the CE-marked nasal spray for the relief of nasal congestion in infants and toddlers aged 6 to 48 months at day 5…
- Conditions
- Nasal Congestion, Common Cold, Allergic Rhinitis, Rhinosinusitis
- Trial name
- NASBY (NCT07257224)
- Testing
- Quinton Medical Nasal Health Baby®
- Where
- 2 sites in Spain
- Volunteers
- 83 people
- Sponsor
- Laboratoires Quinton International S.L.
Nasal Congestion
Study on Hypertonic Saline Nasal Spray
Phytosun decongestant nasal spray is a class I medical device registered in the European Union for the treatment of nasal congestion. The spray contains hypertonic seawater and essential oils.
- Trial name
- PhytosunDecon (NCT02100605)
- Testing
- Phytosun, decongestant, nasal spray
- Where
- United Kingdom
- Volunteers
- 50 people
- Sponsor
- Omega Pharma
Nasal Congestion Associated With the Common Cold
A Multicenter Study of Pseudoephedrine for the Temporary Relief of Nasal Congestion in Children With the Common Cold
This study is designed to confirm the effectiveness of single-ingredient pseudoephedrine in children for the temporary relief of nasal congestion due to the common cold, an indication described under 21 CFR 341.80(b)(1).
- Trial name
- NCT01744106
- Testing
- pseudoephedrine hydrochloride 30 mg tablets
- Where
- 11 sites in United States
- Volunteers
- 565 people
- Sponsor
- Perrigo Company
Seasonal Allergic Rhinitis
Study of the Effect of SCH 900538 on Congestion in Subjects With Seasonal Allergic Rhinitis (Study P05031)(COMPLETED)
This study is to evaluate the effectiveness of a new drug on congestion in subjects with seasonal allergic rhinitis. This effect will be compared to placebo and to the decongestant, pseudoephedrine.
- Trial name
- NCT00673062
- Testing
- SCH 900538, Pseudoephedrine
- Volunteers
- 265 people
- Sponsor
- Merck Sharp & Dohme LLC
Congestion, Nasal
A Pivotal Study to Assess the Effectiveness of Nasal Dilator (Breathe Right Nasal Strips)
This randomized, double-blind, parallel group, placebo-controlled study assessed subjective measures of nasal airway breathing immediately after application in the morning upon awakening after use of breathe right nasal strips…
- Trial name
- NCT03549130
- Testing
- Breathe Right Tan (small/medium) nasal strips
- Where
- 2 sites in United States
- Volunteers
- 130 people
- Sponsor
- GlaxoSmithKline
Seasonal Allergic Rhinitis
4"S" - Seasonal Symptoms Suppression Study
ASIT naïve patients sensitized to grass pollens will be recruited for the study. All of them will be instructed to treat bothersome in-season symptoms when they appear (on as needed, pro re nata basis) with rescue medication.
- Trial name
- 4"S" (NCT02557269)
- Testing
- Xylometazoline - intranasal application, Azelastine - intranasal application, Mometasone furoate - intranasal application
- Where
- Bulgaria
- Volunteers
- 60 people
- Sponsor
- Association Asthma, Bulgaria
Allergic Rhinitis, Tachyphylaxis
Preventing Tolerance to Oxymetazoline in Allergic Rhinitis
The investigators wish to evaluate the effects of decongestants like oxymetazoline and the lessening of this effect with time called 'tolerance'.
- Conditions
- Allergic Rhinitis, Tachyphylaxis, Rhinitis Medicamentosa
- Trial name
- NCT00846326
- Testing
- oxymetazoline-fluticasone propionate, Oxymetazoline
- Where
- 2 sites in United Kingdom
- Sponsor
- Brian J Lipworth
Rhinitis, Allergic, Perennial
LEADER (LEvocetirizine And DEsloratadine in Allergic Rhinitis)
Two weeks study to evaluate the efficacy and safety of Levocetirizine and Desloratadine in patients suffering from Allergic Rhinitis (AR)
- Trial name
- NCT00160589
- Testing
- Levocetirizine
- Volunteers
- 729 people
- Sponsor
- UCB Pharma
Atopic Rhinitis, Atopic Asthma
Vibroacoustic Therapy With Oscillating Positive Expiratory Pressure in the Treatment of Nasal Congestion
This is a prospective study. It enrolls subjects with allergic rhinitis, with or without asthma, who have nasal congestion as the main symptom and meet the inclusion criteria, aiming to evaluate the efficacy and safety of…
- Trial name
- VAT (NCT07114107)
- Testing
- VPAT (Vibratory Positive Pressure Therapeutic Apparatus）, basic medications (antihistamines, mometasone furoate nasal spray, ICS-LABA, OPEP（Oscillating Positive Expiratory Pressure device）
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Nasal Congestion and Inflammations
Sonu Nasal Congestion Relief Study in Patients Suffering From Moderate to Severe Nasal Congestion
To demonstrate the safety and effectiveness of Sonu for the treatment of patients suffering from moderate to severe nasal congestion.
- Trial name
- SCORE (NCT05821842)
- Testing
- Sonu
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- Third Wave Therapeutics
Nasal Congestion
Market Potential of Carbon Dioxide Nasal Spray
Carbon dioxide (CO2) is a naturally occurring gas that readily diffuses across body tissues and membranes. Data from earlier clinical studies conducted in 975 subjects with allergic rhinitis have shown that nasally administered…
- Trial name
- NCT02113449
- Testing
- Carbon Dioxide
- Where
- 4 sites in United States
- Volunteers
- 147 people
- Sponsor
- GlaxoSmithKline
Nasal Congestion
A Nasal Spray for Relief of Nasal Congestion in Infants and Toddlers With Common Cold
The study will evaluate the safety and efficacy of the study medical device plus standard of care versus standard of care in subjects between 3 and 48 months (inclusive) presenting symptoms of a common cold.
- Trial name
- NCT05365789
- Testing
- Blocked Nose Baby nasal spray, Standard of care
- Where
- Poland
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Church & Dwight Company, Inc.
Nasal Congestion
Efficacy and Safety of Pediatric Drugs in Nasal Congestion
The purpose of this study is to evaluate the efficacy of the Naridrin in improving nasal congestion.
- Trial name
- NCT02601235
- Testing
- Naridrin, Afrin
- Where
- Brazil
- Volunteers
- 292 people
- Sponsor
- EMS
Sleep Disorders, Congestion, Nasal
Exploratory Subjective Sleep Study of a Prototype Nasal Dilator
The purpose of this exploratory study is to evaluate the subjective measures of congestion and sleep quality in subjects who suffer from chronic nasal congestion and report trouble with their sleep.
- Trial name
- NCT01122849
- Testing
- Prototype Nasal Dilator, Marketed Nasal Strip
- Where
- 2 sites in United States
- Volunteers
- 61 people
- Sponsor
- GlaxoSmithKline
Allergic Rhinitis
Acupuncture for Nasal Congestion in Allergic Rhinitis
Allergic rhinitis (AR) is a disorder that affects more than 500 million people worldwide. Nasal congestion is one of the most general and bothersome symptoms in rhinitis, which impacts the quality of life (QOL).
- Trial name
- ANCAR (NCT05709977)
- Testing
- Acupuncture, Antihistamine nasal spray
- Where
- Netherlands
- Volunteers
- 11 people
- Sponsor
- Johanna Maria Vermeulen
Health Knowledge, Attitudes, Practice, Sneezing
"Anticipatory Guidance in the Nursery and Its Impact on Non-urgent Emergency Department Visits"
Kennedy et al, in a study of pediatric Emergency Department (ED) use by newborns less than 14 days of age, revealed that half of all visits in this population were non-acute problems.
- Conditions
- Health Knowledge, Attitudes, Practice, Sneezing, Constipation, Nasal Congestion and Inflammations
- Trial name
- NCT01859065
- Testing
- Intensified anticipatory guidance, Routine
- Where
- United States
- Volunteers
- 323 people, healthy volunteers welcome
- Sponsor
- Bronx-Lebanon Hospital Center Health Care System
Itching, Runny Nose
Efficacy and Safety of Auricular Acupressure in Treating Allergic Rhinitis
Allergic rhinitis (AR) is a global health problem affecting approximately 10% to 40% of the population worldwide, with an increasing trend. It significantly impacts health and quality of life.
- Conditions
- Itching, Runny Nose, Sneezing, Nasal Congestion
- Trial name
- NCT06323304
- Testing
- Auricular acupressure, Standard treatment
- Where
- Vietnam
- Volunteers
- 90 people
- Sponsor
- University of Medicine and Pharmacy at Ho Chi Minh City
Covid19, Nasopharyngitis
BNO 1030 Extract (Imupret) in the Treatment of Mild Forms of COVID-19
According to WHO (World Health Organisation) data, about 40% of patients with COVID-19 (Corona Virus SARS-CoV-2) have a mild course of the disease, namely, cases of mild course are of great danger from the point of view of the…
- Conditions
- Covid19, Nasopharyngitis, Anosmia, Fever
- Trial name
- NCT04797936
- Testing
- BNO 1030, Standard care
- Where
- Ukraine
- Volunteers
- 133 people
- Sponsor
- Ivano-Frankivsk National Medical University