Clinical trials: Congestive Cardiac Failure
Heart Failure, Congestive
The Effect of Alfa-Adrenergic Receptor Blockade on Insulin-Stimulated Forearm Glucose Uptake and Metabolism in Chronic Heart Failure
The activity of the sympathetic nervous system seems to influence the uptake (and handling) of glucose by the skeletal muscle of the forearm.
- Trial name
- NCT00132106
- Testing
- phentolamine
- Where
- Netherlands
- Sponsor
- Radboud University Medical Center
Congestive Heart Failure, Angina Pectoris
Randomized Controlled Trial of Health Care to Elderly Patients.
To study the efficacy of multicomponent treatment and care for patients with acute illness or deterioration of a chronic disease at a nursing home in primary health care compared to traditional treatment at hospital.
- Conditions
- Congestive Heart Failure, Angina Pectoris, Asthma, Pneumonia
- Trial name
- NCT00235404
- Testing
- Multicomponent treatment, usual care
- Where
- Norway
- Volunteers
- 142 people
- Sponsor
- Norwegian University of Science and Technology
Dyspnea, Peripheral Edema
NT-proBNP and New Biomarkers in Patients With Dyspnea and/or Peripheral Edema
The objectives of this study are to: Evaluate the sensitivity and specificity of NT-proBNP (N-terminal prohormone brain natriuretic peptide) and new biomarker measurements for the diagnosis of heart failure in patients with acute…
- Trial name
- MANPRO (NCT00143793)
- Where
- Germany
- Volunteers
- 400 people
- Sponsor
- Universitätsmedizin Mannheim
Covid19, Acute Cor Pulmonale
Cardiac Performance in Mechanically Ventilated COVID-19 Patients
Although COVID-19 affects primarily the respiratory system, several studies have shown evidence of cardiovascular alterations. Increased troponin levels were observed in a significant proportion of patients and this alteration…
- Conditions
- Covid19, Acute Cor Pulmonale, Cardiac Failure
- Trial name
- NCT04628195
- Where
- Chile
- Volunteers
- 100 people
- Sponsor
- Pontificia Universidad Catolica de Chile
Heart Failure，Congestive
Home BIA Management System in Patients With Heart Failure
This study is a prospective, multi-center, open label, randomized clinical trial conducted in the republic of Korea. The objective of this study is to evaluate the efficacy and safety of the treatment using home bioelectrical…
- Trial name
- NCT05177081
- Testing
- Preemptive management using home BIA monitoring system
- Where
- 2 sites in South Korea
- Volunteers
- 40 people
- Sponsor
- Korea University Guro Hospital
Myocardial Ischemia, Congestive Heart Failure
Stem Cell Study for Patients With Heart Failure
The purpose of this study is to determine if cell therapy with your own cells (autologous cells) delivered with a catheter to regions of the heart with poor blood flow will be safe and if it will improve your ejection fraction…
- Conditions
- Myocardial Ischemia, Congestive Heart Failure, Cardiovascular Disease
- Trial name
- NCT00346177
- Testing
- Autologous Stem Cells
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Losordo, Douglas, M.D.
Congestive Heart Failure
Preoperative Significant Clinical Findings Using Focused Ultrasound Examination
The purpose of this study is to determine whether a focused ultrasound examination for the heart, lungs and abdomen, preformed by a trained anesthesiologist, can reveal significant clinical findings in elderly patients before…
- Trial name
- NCT02824692
- Testing
- heart lungs and abdomen ultrasound
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Rambam Health Care Campus
Congestive Heart Failure
Study to Evaluate Cardiac Hemodynamics and Safety of SLV320 in Subjects With Congestive Heart Failure
The study is a randomized, placebo controlled, multi-center, single dose study to evaluate cardiac hemodynamics and safety of iv SLV320 in 110 subjects with congestive heart failure requiring diuretic treatment.
- Trial name
- NCT00160134
- Testing
- SLV320
- Where
- Germany
- Sponsor
- Solvay Pharmaceuticals
Congestive Heart Failure, Chronic Obstructive Pulmonary Disease
Patient Oriented Discharge Summary Impact Study
Improving the patient experience has become a major focus of quality improvement efforts in Ontario and in health systems worldwide.
- Conditions
- Congestive Heart Failure, Chronic Obstructive Pulmonary Disease, Pneumonia, Hip Fracture
- Trial name
- PODS (NCT02673892)
- Testing
- Patient Oriented Discharge Summary
- Where
- Canada
- Volunteers
- 581 people
- Sponsor
- University Health Network, Toronto
Heart Failure, Congestive
Skeletal Muscle Dysfunction in Heart Failure
Patients suffering from congestive heart failure report reduced exercise capacity. This skeletal muscle dysfunction is also detectable when using small muscle groups which should not put any demand on the heart.
- Trial name
- NCT00156234
- Testing
- One-knee extension ergometer
- Where
- 2 sites in Norway
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Ullevaal University Hospital
Heart Failure
Congestive Heart Failure Outreach Program
Heart failure is a very common condition and is one of the main reasons people are admitted to hospital. There are many things people with heart failure can do to manage their condition at home.
- Trial name
- COPE (NCT00371085)
- Testing
- education
- Where
- Canada
- Volunteers
- 539 people
- Sponsor
- University of Alberta
Heart Failure, Heart Transplantation
Medical Care Versus Ventricular Assist Device for the Management of End-stage Heart Failure (MEVADE)
End-stage heart failure (ESHF) represents a major burden in terms of quality of life, mortality and costs. The current practice in France is to treat patients with ESHF by a combination of drugs and lifestyle interventions before…
- Conditions
- Heart Failure, Heart Transplantation, Heart-Assist Devices
- Trial name
- MEVADE (NCT03105726)
- Volunteers
- 224 people
- Sponsor
- Joe Elie Salem
Congestive Heart Failure
Echocardiography and Peak Endocardial Acceleration (PEA) Measurements in Cardiac Resynchronization Therapy (CRT)
This study used an external endocardial acceleration sensor (sonR sensor), placed on the patient's chest, to time the closure of aortic and mitral valves, and compared its performance with echocardiography.
- Trial name
- NCT01066078
- Testing
- Echocardiography and SonR recording
- Where
- 4 sites in France
- Volunteers
- 216 people
- Sponsor
- LivaNova
Myocardial Ischemia, Heart Failure, Congestive
Stem Cell Therapy in Chronic Ischemic Heart Failure
The purpose of this study is to determine whether intracoronary bone marrow transplantation can improve left ventricular ejection fraction in patients with severe ischemic heart failure and no other option for standard therapies…
- Trial name
- NCT00235417
- Testing
- Bone marrow transplantation
- Where
- Denmark
- Volunteers
- 35 people
- Sponsor
- Odense University Hospital
Heart Failure, Congestive
PREVENT-HF: Prevention of Heart Failure Events With Impedance Cardiography Testing
The purpose of this study is to determine whether outpatient therapeutic management guided by impedance cardiography (ICG), in addition to standard clinical assessment, will result in a longer time in days to the first heart…
- Trial name
- NCT00409916
- Testing
- BioZ Dx
- Where
- 3 sites in United States
- Volunteers
- 500 people
- Sponsor
- CardioDynamics
Sudden Cardiac Death, Arrhythmias
Genetic Risk Assessment of Defibrillator Events
Arrhythmias remain a major health problem, causing at least 250,000 deaths annually in the United States. Pharmacological treatments often do more harm than good, and device therapies are limited by high cost and effects on…
- Conditions
- Sudden Cardiac Death, Arrhythmias, Congestive Heart Failure, Cardiomyopathy
- Trial name
- GRADE (NCT02045043)
- Where
- 6 sites in United States
- Volunteers
- 1,807 people
- Sponsor
- University of Iowa
Congestive Heart Failure
Autonomic Regulation Therapy in Heart Failure With Preserved Ejection Fraction
The ANTHEM-HFpEF Study is designed to demonstrate the safety and efficacy of vagus nerve stimulation (VNS) with the Cyberonics VNS Therapy System for the treatment of subjects with symptomatic heart failure with preserved and…
- Trial name
- NCT03163030
- Testing
- Vagus Nerve Stimulation (VNS)
- Where
- India
- Volunteers
- 52 people
- Sponsor
- Cyberonics, Inc.
Heart Failure, Congestive
PET Scan to Determine Areas of Blood Flow and Activity in the Hearts of Patients With Heart Disease Taking Beta-Blockers
The human heart is divided into four chambers. One of the four chambers, the left ventricle, is the chamber mainly responsible for pumping blood out of the heart into the circulation.
- Trial name
- NCT00001402
- Testing
- PET scan
- Where
- United States
- Volunteers
- 130 people
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Acute Decompensated Heart Failure
IC14 for Treatment of Acute Decompensated Heart Failure
The goal of this clinical trial is to learn if drug atibuclimab (IC14) works to treat adults hospitalized with acute decompensated heart failure (ADHF). It will also learn about the safety of IC14.
- Trial name
- NCT06556810
- Testing
- Atibuclimab (IC14)
- Where
- 2 sites in United States
- Volunteers
- 10 people
- Sponsor
- Implicit Bioscience
Congestive Heart Failure, Metastatic Cancer
Advance Care Planning in the Emergency Department
This is a two-armed, parallel-design, pre-/post-intervention assessment study. The investigators will conduct a randomized controlled trial for ED GOAL on a cohort of 120 older adults with serious illness to collect…
- Conditions
- Congestive Heart Failure, Metastatic Cancer, Chronic Kidney Disease Requiring Chronic Dialysis, Chronic Obstructive Pulmonary Disease
- Trial name
- NCT05209880
- Testing
- ED GOAL
- Where
- United States
- Volunteers
- 141 people
- Sponsor
- Brigham and Women's Hospital