Clinical trials: Congestive Heart Failure(CHF)
Rehabilitation After Heart Failure
Rehabilitative Care to Patients With Heart Failure
Hypothesis and objectives of the study Systematic preparation of rehabilitation plan for rehabilitation in Phase III based on identification of self-care behavior patients with heart failure in NYHA class II and III, leading to…
- Trial name
- NCT01239667
- Testing
- Individual oriented planning of the rehabilitation program for patients with heart failure
- Where
- Denmark
- Volunteers
- 194 people
- Sponsor
- University College Absalon
Heart Failure, Congestive
BNP Testing in Patients With SOB on Presentation to ED
A trial to examine whether a new heart failure blood test can improve the outcome of patients presenting to the Emergency Department with shortness of breath.
- Trial name
- NCT00163709
- Testing
- BNP test
- Where
- Australia
- Volunteers
- 600 people
- Sponsor
- Bayside Health
Heart Failure With Normal Ejection Fraction
The Heart Failure With Preserved Ejection Fraction (HFpEF) Pathophysiology Study.
The study addresses the hypothesis that a gradual build-up in arterial resistance and microvascular endothelial dysfunction due to common comorbidities such as hypertension and diabetes mellitus, on top of age related vascular…
- Trial name
- IDENTIFY-HF (NCT03186833)
- Testing
- no intervention
- Where
- United Kingdom
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- University Hospitals Coventry and Warwickshire NHS Trust
Right Heart Failure
Accelerated LBBP for Patients With RHF and Severe TR
This study is a prospective, single-arm, target value clinical trial. We plan to prospectively enroll and follow 24 patients across three centers nationwide who have a low baseline heart rate (HR ≤ 60 bpm), meet the indication…
- Trial name
- ARCP (NCT07470047)
- Testing
- permanent pacemaker implantation
- Where
- 3 sites in China
- Volunteers
- 24 people
- Sponsor
- Shanghai Zhongshan Hospital
Heart Failure, Anemia
Iron Supplementation in Heart Failure Patients With Anemia: The IRON-HF Study
Anemia has been demonstrated to be a common finding in patients with heart failure (HF). Previous studies in hospitalized patients with HF have found a prevalence of anemia ranging from 15% to 63%.
- Trial name
- NCT00386126
- Testing
- Iron Sucrose IV 200mg, once a week, for 5 weeks, Ferrous sulfate 200mg PO TID, for 8 weeks
- Where
- Brazil
- Volunteers
- 117 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Heart Failure With Preserved Ejection Fraction, Cardiovascular Diseases
Staging Heart Failure With Preserved Ejection Fraction
Heart failure with preserved ejection fraction (HFpEF) is considered a systemic condition in which the prevalence of cardiovascular, metabolic, pulmonary and renal conditions determine the extent of cardiac involvement.
- Conditions
- Heart Failure With Preserved Ejection Fraction, Cardiovascular Diseases, Heart Failure
- Trial name
- StageHFpEF (NCT06931015)
- Testing
- No interventions
- Where
- Russia
- Volunteers
- 700 people
- Sponsor
- I.M. Sechenov First Moscow State Medical University
Heart Failure, Atrial Fibrillation
Mascot Study: Management of Atrial Fibrillation (AF) Suppression in AF-Heart Failure (HF) COmorbidity Therapy
The purpose of this study is to evaluate whether adding AF Suppression™ to cardiac resynchronization therapy (CRT) improves the prognosis of heart failure patients benefiting from cardiac resynchronization therapy.
- Conditions
- Heart Failure, Atrial Fibrillation, Ventricular Dysfunction
- Trial name
- MASCOT (NCT00187252)
- Testing
- Atrial Overdrive Pacing
- Where
- Italy
- Volunteers
- 380 people
- Sponsor
- Abbott Medical Devices
Heart Failure With Preserved Ejection Fraction
Ketogenic Diet vs Mixed Diet in Patients With Heart Failure
This study is being done to evaluate the effects of a low carbohydrate ketogenic diet (KD) versus a low-fat diet (MD) on exercise tolerance in participants with heart failure with normal pumping function and diabetes or…
- Trial name
- NCT06081543
- Testing
- Ketogenic diet, Low-fat Mixed diet
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Ohio State University
Dyspnea, Paroxysmal, Heart Failure, Left Sided
Management of Cardiogenic Pulmonary Edema (RENAU-OAP)
The prevalence of heart failure is estimated to 2.3 percent of the adult population and strongly increases with age, according to french disability-health surveys.
- Trial name
- RENAU-OAP (NCT03148847)
- Testing
- Baseline care, Referential's dissemination
- Where
- France
- Volunteers
- 859 people
- Sponsor
- Centre Hospitalier Annecy Genevois
Heart Failure, Congestive
HEAL-HF: A Cardiac Resynchronization Therapy (CRT) Outcomes Study
The literature shows that approximately 40% of individuals who receive a cardiac resynchronization therapy (CRT) device for symptomatic congestive heart failure (CHF) do not have a clinical benefit from the device.
- Trial name
- NCT00370526
- Testing
- Acute hemodynamic assessment using PV Loops (CD Leycom, The Netherlands) during LV lead placement
- Where
- 5 sites in United States, Canada and 1 more
- Volunteers
- 100 people
- Sponsor
- Stereotaxis
Heart Failure
Influence of Neurohormonal Blockade on Natriuresis in Heart Failure Patients
Heart failure is a condition that can affect a person's health and daily life. In this study, we aim to investigate how diuretic medications work and how they affect patients with heart failure.
- Trial name
- uGDMT (NCT07781826)
- Testing
- Neurohormonal blockade intensification
- Where
- Poland
- Volunteers
- 80 people
- Sponsor
- Wroclaw Medical University
ST Elevation Myocardial Infarction (STEMI), Coronary Artery Disease
Metformin to Reduce Heart Failure After Myocardial Infarction
The investigators will evaluate the effect of metformin therapy during 4 months in non-diabetic patients following ST-elevation myocardial infarction on left ventricular ejection fraction as measured with cardiac magnetic…
- Conditions
- ST Elevation Myocardial Infarction (STEMI), Coronary Artery Disease, Heart Failure, Diabetes
- Trial name
- GIPS-III (NCT01217307)
- Testing
- Metformin
- Where
- Netherlands
- Volunteers
- 380 people
- Sponsor
- University Medical Center Groningen
Heart Failure, Kidney Failure
New Biomarkers in Heart- and Renal Failure
In this study, prognostically relevant biomarkers for cardiovascular / renal insufficiencies will be clinically evaluated, to improve the course of assessment of such disease and to gain new insights into the typical course of…
- Trial name
- IM19 Register (NCT02830464)
- Where
- Germany
- Volunteers
- 500 people
- Sponsor
- RWTH Aachen University
Heart Failure With Preserved Ejection Fraction, Healthy
Understanding the Mechanisms of Diastolic Dysfunction
Heart failure is a clinical syndrome marked by breathlessness, even at low levels of exertion, general fatigue, and fluid retention and is estimated to affect 5.1 million people in the United States.
- Trial name
- NCT03340233
- Testing
- MRI (cardiac) off-label use gadolinium contrast (IND exempt), MRI (cardiac)
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Heart Failure, ESKD
Study of Diastolic Dysfunction in ESKD in Hemodialysis Patient
To Asses the prevalence , pattern , and severity of diastolic dysfunction in patients ESKD undergoing regular dialysis and to investigate its correlation with clinical parameters dialysis-related factors and echocardiographic…
- Conditions
- Heart Failure, ESKD, Hemodialysis Patients
- Trial name
- NCT07180888
- Testing
- Echocardiography, Echocardiographic assessment of diastolic dysfunction
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Sohag University
Acute Heart Failure
Effect of Short-term Prednisone Therapy on C-reactive Protein in Patients With Acute Heart Failure
This is a multicenter, parallel-group, randomized, open-label, controlled trial. Patients with a diagnosis of acute heart failure (AHF) in the emergency department (ED) or after emergency presentation to hospital will be screened…
- Trial name
- CORTAHF (NCT05916586)
- Testing
- Prednisone
- Where
- 3 sites in Armenia
- Volunteers
- 101 people
- Sponsor
- Heart Initiative
Heart Failure Acute, Heart Failure
Cardiac Output Autonomic Stimulation Therapy for Heart Failure - Hemodynamic Effects
A single-arm study to observe NeuroTronik Cardiac Autonomic Nerve Stimulation (CANS) Therapy System hemodynamic and other physiologic effects.
- Trial name
- COAST-HF FX (NCT03542123)
- Testing
- NeuroTronik CANS Therapy® System
- Where
- Paraguay
- Volunteers
- 30 people
- Sponsor
- NeuroTronik Inc.
Cardiac Failure, Low Cardiac Output Syndrome
Landiolol in Mitral Valve Surgery
Chronic mitral regurgitation is the most common valvular abnormality worldwide, it occurs in 10% of the general population and its prevalence increases with age.
- Trial name
- LUNA (NCT06793670)
- Testing
- Landiolol
- Where
- 13 sites in Italy
- Volunteers
- 1,500 people
- Sponsor
- Università Vita-Salute San Raffaele
Heart Failure
A Trial to Study Neladenoson Bialanate Over 20 Weeks in Patients With Chronic Heart Failure With Reduced Ejection Fraction
The objective of the study is to find the optimal dose of once daily oral neladenoson bialanate (BAY 1067197) when given in addition to standard therapy for heart failure with reduced ejection fraction (HFrEF).
- Trial name
- PANTHEON (NCT02992288)
- Testing
- Neladenoson bialanate (BAY1067197)
- Where
- 75 sites in United States, Belgium and 9 more
- Volunteers
- 427 people
- Sponsor
- Bayer
Chagas Cardiomyopathy, Chronic Heart Failure
Chagas Cardiomyopathy Bisoprolol Intervention Study: Charity
Chagas disease (CD) is the major cause of disability secondary to tropical diseases in young adults from Latin America. In this region 20 million people are currently infected by T. cruzi, the etiologic agent for CD.
- Trial name
- NCT00323973
- Testing
- Bisoprolol
- Where
- Colombia
- Volunteers
- 500 people
- Sponsor
- Fundación Cardiovascular de Colombia
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.