Clinical trials: Congestive Heart Failure(CHF)
Heart Failure, Heart Failure, Systolic
Pharmacist-Assisted Titration of Rx to Implement Optimal Medical Therapy for Heart Failure
Many Veterans who are hospitalized with heart failure do not receive all the recommended heart medications at the right doses before they leave the hospital or in the weeks following discharge.
- Trial name
- PATRIOT-HF (NCT07714239)
- Testing
- Pharmacist/Cardiologist Virtual Team Digital Consultation
- Where
- United States
- Volunteers
- 585 people
- Sponsor
- VA Office of Research and Development
Diabete Mellitus, Heart Failure
Effect of Empagliflozin 10 vs 25 mg on LV Remodeling in Diabetic Patients With Anterior STEMI With Reduced LVEF
This study is investigating how the medication Empagliflozin affects the heart's structure and function in patients with heart disease.
- Conditions
- Diabete Mellitus, Heart Failure, Remodeling, Left Ventricle
- Trial name
- EMPA-DMMI (NCT07169981)
- Testing
- Empagliflozin 10 MG [Jardiance], empagliflozin (Jardiance) 25 mg
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Ain Shams University
Heart Failure
Predischarge Initiation of Ivabradine in the Management of Heart Failure (PRIME-HF)
The PRIME-HF study is a multi-center, patient-level, randomized, open-label study of approximately 450 patients with reduced (left ventricular ejection fraction) LVEF of ≤ 35% and heart-rate ≥70 beats per minute (bpm) who are…
- Trial name
- PRIME-HF (NCT02827500)
- Testing
- ivabradine, Usual Care
- Where
- 20 sites in United States
- Volunteers
- 104 people
- Sponsor
- Duke University
Heart Failure
Effect of Intra-session Exercise Modes Sequence on Ventricular Function in Patients With Chronic Heart Failure
The aim of this study was to investigate the effect of intra-session exercise modes sequence on ventricular function in patients with chronic heart failure.
- Trial name
- NCT06626542
- Testing
- resistance and aerobic training exercises
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Heart Failure
Mobile Integrated Health in Heart Failure
The purpose of this study is to compare how two different types of care after a hospitalization reduce hospital readmissions and symptom burden.
- Trial name
- NCT04662541
- Testing
- Mobile Integrated Health (MIH), Transitions of care coordinator (TOCC)
- Where
- 3 sites in United States
- Volunteers
- 2,005 people
- Sponsor
- Columbia University
Heart Failure
Evaluation of the Effect of Liposomal L-Arg and Vit C Integration on Mitochondrial Function in Patients With Heart Failure
Pilot study to assess the effect of L-Arg and Vit C liposomal supplementation on mitochondrial function in patients with heart failure, through analysis of the viability of mitochondria isolated from peripheral blood of…
- Trial name
- Mito-HF (NCT06044194)
- Testing
- L-arginine and liposomal vitamin C
- Where
- Italy
- Volunteers
- 56 people
- Sponsor
- Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
Heart Failure, Cardiomyopathies
Towards Understanding the Phenotype of Cardiovascular Disease in CKD - TRUE-Type-CKD Study
Premature cardiovascular disease (CVD) is the leading cause of death in patients with kidney disease (CKD). Excessive cardiac mortality is thought to be secondary to non-atherosclerotic processes, with left ventricular (LV)…
- Conditions
- Heart Failure, Cardiomyopathies, Chronic Kidney Diseases, Hypertrophy, Left Ventricular
- Trial name
- TRUE-TypeCKD (NCT03749551)
- Testing
- cardiac magnetic resonance (CMR) post haemodialysis
- Where
- Germany
- Volunteers
- 276 people
- Sponsor
- Johann Wolfgang Goethe University Hospital
Chronic Heart Failure
Computerized Guideline in Heart Failure: Implementation Process and Impact Evaluation
Objective: To assess the effectiveness of implementation process of an electronic Heart Failure guideline in primary care in the city of Barcelona.
- Trial name
- NCT00792402
- Where
- Spain
- Volunteers
- 13,008 people
- Sponsor
- Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina
Heart Failure With Reduced Ejection Fraction
VITAL - the Heart Failure With Reduced Ejection Fraction Sub-study
Heart failure affects over 1 million people in the United Kingdom. Approximately 50% have heart failure with reduced ejection fraction (HFrEF), a condition where the heart muscle does not contract properly.
- Trial name
- NCT06534151
- Testing
- CRT implantation
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- University College, London
Acute Heart Failure, Pulmonary Congestion
LUS in Acute Heart Failure Therapeutic Adaptation
Evaluate lung ultrasound aspect according to diuretics dosage evolution in patients hospitalized for acute heart failure.
- Trial name
- EPPICA (NCT04633629)
- Testing
- Lung ultrasound
- Volunteers
- 94 people
- Sponsor
- University Hospital, Grenoble
Heart Failure, Chronic Heart Failure
Relationships and Differences Analysis in Heart Failure
This study characterizes heart failure patients who attended the University Hospital Würzburg. The primary aim is a better understanding of the relationships and differences between the subgroups HFrEF (EF < 40%), HFmrEF (EF…
- Conditions
- Heart Failure, Chronic Heart Failure, Chronic Heart Disease
- Trial name
- REDEAL-HF (NCT03966729)
- Testing
- Time (outcome)
- Where
- Germany
- Volunteers
- 3,000 people
- Sponsor
- Wuerzburg University Hospital
Heart Failure New York Heart Association Class III, Heart Failure New York Heart Association Class IV
Levosimendan In Ambulatory Heart Failure Patients
The objective of the study is to determine the efficacy of repeated infusions of levosimendan in the group of outpatients with advanced systolic heart failure (HF).
- Conditions
- Heart Failure New York Heart Association Class III, Heart Failure New York Heart Association Class IV, Heart Failure, Systolic, Heart Failure With Reduced Ejection Fraction
- Trial name
- LEIA-HF (NCT04705337)
- Testing
- Levosimendan
- Where
- 14 sites in Poland
- Volunteers
- 70 people
- Sponsor
- Medical University of Bialystok
Diastolic Heart Failure
Validation of New Non-Invasive Parameters of Diastolic Suction in the Left Ventricle
It is known that, at the end of the cardiac ejection period, potential energy is stored in elastic fibers of the heart, which promotes the suction of blood from the atria during early filling.
- Trial name
- NCT02315859
- Where
- Switzerland
- Volunteers
- 40 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Heart Failure
Improving Risk Stratification of Emergency Department Patients With Acute Heart Failure
The primary goal is to build and test a previously developed and validated risk model and clinical decision support tool embedded within the electronic health record to improve risk stratification of emergency department (ED)…
- Trial name
- NCT06065761
- Testing
- Comprehensive ED heart failure management tool
- Where
- 21 sites in United States
- Volunteers
- 17,459 people
- Sponsor
- Kaiser Permanente
Heart Failure
Effects of Chocolate in Patients With Chronic Heart Failure
The aim of the present study is to investigate whether in patients with chronic heart failure endothelial dysfunction and baroreceptor function is altered by ingestion of a flavonoid-rich dark chocolate in comparison to placebo…
- Trial name
- NCT00538941
- Testing
- Nestlé Noir intense 40 grx2
- Where
- Switzerland
- Volunteers
- 22 people
- Sponsor
- University of Zurich
Heart Failure Attributable to Severe Tricuspid Regurgitation
TRICuspid Intervention in Heart Failure Trial
Aims: Tricuspid regurgitation (TR) is a detrimental disease frequently diagnosed in patients with right-sided heart failure (HF).
- Trial name
- TRIC-I-HF (NCT04634266)
- Testing
- Transcatheter tricuspid valve treatment (TTVT)
- Where
- 28 sites in Germany
- Volunteers
- 360 people
- Sponsor
- LMU Klinikum
Heart Failure
Patient Journey in Hospital With Heart Failure in Turkish Population
The purpose of this study is to compose a national database of the etiologies, clinical and demographic characteristics, using diagnostic tests, precipitating and risk factors, management of from intensive care unit or coronary…
- Trial name
- JournayHF-TR (NCT02487056)
- Testing
- Demographic and clinical characteristics, clinical history, symptoms and signs, initial emergency department evaluation, and subsequent inpatient management of HF patients
- Where
- Turkey (Türkiye)
- Volunteers
- 1,622 people
- Sponsor
- Ege University
Chronic Heart Failure
Exercise Improve Sympathetic Modulation in Chronic Heart Failure Patients
The purpose of this study is to verify the effects of exercise training on sympathetic modulation and arterial baroreflex control in patients with chronic heart failure.
- Trial name
- NCT02219451
- Testing
- exercise training
- Where
- Brazil
- Volunteers
- 26 people
- Sponsor
- University of Sao Paulo General Hospital
Congestive Heart Failure
THalidomide on Left ventricUlar Morphology aND Function in congEstive heaRt Failure
Several studies have shown that inflammation and matrix degradation have pathogenic effects on the myocardium by influencing heart contractility, inducing hypertrophy, degrading the matrix, or enhancing fibrosis, thus…
- Trial name
- THUNDER (NCT01640639)
- Testing
- Thalidomide
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- University of Roma La Sapienza
Heart Failure, Palliative Care
Promoting Palliative Care for People With Heart Failure
This project will develop and test a novel clinical decision support tool (CDS) that encourages timely referral to palliative care for people hospitalized with heart failure.
- Trial name
- P3HF (NCT06933875)
- Testing
- Clinical Decision Support Tool
- Where
- 2 sites in United States
- Volunteers
- 2,260 people
- Sponsor
- Yale University
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