Clinical trials: Congestive Heart Failure(CHF)
Heart Failure With Preserved Ejection Fraction, Cardiovascular Morbidity
Arterial Stiffening as a Predictor for Diastolic Cardiac Dysfunction and HFpEF
Patients at risk for developing heart failure with preserved ejection fraction (HFpEF) will undergo a structured clinical assessment, transthoracic echocardiography and pulse-wave analysis to investigate the association of…
- Trial name
- ARTSPREDICTION (NCT06208007)
- Where
- Germany
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University Medical Center Goettingen
Acute Decompensated Heart Failure
Effect of Providing Education and Patient's Inferior Vena Cava Ultrasound Images on Adherence to a Heart Failure Regimen
Heart failure is a common, costly, and disabling condition characterized by recurrent exacerbations. Episodes of acute decompensated heart failure (ADHF) account for the largest proportion of admissions and 30-day readmissions to…
- Trial name
- NCT03488979
- Testing
- educational interventional group
- Volunteers
- 100 people
- Sponsor
- Johns Hopkins University
Heart Failure
Effect of Flozin (dapagliflozin) Administration on Myocardial and Peripheral Vascular Remodeling
The aim of this study is to assess the effect of treatment with flozin (dapagliflozin 10mg once a day) on haemodynamic parameters and myocardial and peripheral vascular remodeling in patients with NYHA class II-III heart failure.
- Trial name
- DAPA-REMO (NCT06679179)
- Where
- Poland
- Volunteers
- 50 people
- Sponsor
- Poznan University of Medical Sciences
Duchenne Muscular Dystrophy
Wearable Technology to Evaluate Hyperglycemia and HRV in DMD
Duchenne muscular dystrophy (DMD) is an X-linked disorder that causes muscle wasting, cardiopulmonary failure, and premature death.
- Trial name
- NCT06124196
- Testing
- wearable technology
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Heart Failure, Decompensated Heart Failure
Monocyte Phenotypic Changes in Heart Failure
There are many treatments that can improve how long and how well people live with heart failure when they are outside the hospital.
- Trial name
- NCT02997462
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Cardiomyopathies, Heart Failure
Inflammatory Cardiomyopathy Baseline Cohort (SFB/TR19)
cohort of cardiomyopathy patients (suspected or validated inflammatory cardiomyopathy) recruited at baseline by the SFB-TR19 project.
- Trial name
- SFB/TR19 (NCT02970227)
- Testing
- Observation
- Where
- Germany
- Volunteers
- 920 people
- Sponsor
- University Medicine Greifswald
Chronic Heart Failure
VItamiN D treatIng Chronic heArT Failure (the Effect of Vitamin D Supplementation in Patients With Heart Failure)
VINDICATE 2 will be a randomised, placebo-controlled, parallel group, double-blind study of vitamin D versus placebo in otherwise optimally-managed patients with CHF due to LVSD and vitamin D deficiency (<50nmol/L).
- Trial name
- VINDICATE2 (NCT03416361)
- Testing
- 4000IU Vitamin D3
- Where
- United Kingdom
- Volunteers
- 1,253 people
- Sponsor
- University of Leeds
Heart Failure NYHA Class II, Heart Failure NYHA Class III
CardioMEMS HF System Real-World Evidence Post-Approval Study
The purpose of this post-approval study (PAS) is to evaluate the long-term safety and effectiveness of the CardioMEMS™ HF System using real-world evidence (RWE) methods.
- Trial name
- NCT06306573
- Testing
- CardioMEMS HF System
- Where
- United States
- Volunteers
- 2,500 people
- Sponsor
- Abbott Medical Devices
Decompensated Heart Failure, Hyponatremia
Regional Tolvaptan Registry
Low blood sodium is a common observation in patients presenting with heart failure and is associated with increased mortality, prolonged hospital stay, and repeat hospital visits.
- Trial name
- Tolvaptan (NCT02666651)
- Testing
- Tolvaptan, No intervention
- Where
- Canada
- Volunteers
- 25 people
- Sponsor
- Cardiology Research UBC
Heart Disease, Heart Failure
Investigating Systemic and Local Vascular Responses to Apelin in the Context of Renin-angiotensin Upregulation
The apelin-APJ system is a relatively new discovery. It has generated interest in part due to it's apparent ability to counteract the renin-angiotensin system, which is frequently overactive in many cardiovascular disease.
- Conditions
- Heart Disease, Heart Failure, Vasodilatation
- Trial name
- NCT00901719
- Testing
- Apelin, Acetylcholine, Sodium nitroprusside
- Where
- United Kingdom
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Edinburgh
Diabetes, Asthma
Integrated Care (IC) Models for Patient-Centered Outcomes
Multiple chronic conditions (MCC) are widely recognized as the U.S. public health challenge of the 21st century. These physical and behavioral health conditions take a large toll on those living with chronic diseases, including…
- Conditions
- Diabetes, Asthma, Chronic Obstructive Pulmonary Disease, Hypertension
- Trial name
- IC (NCT03451630)
- Testing
- High-Touch, High-Tech, Optimal Discharge Planning
- Where
- United States
- Volunteers
- 1,400 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Heart Failure
Heart Failure Treatment Pattern Analysis of HF Patients in HF Centers and Non-HF Centers in China
This is a retrospective, researcher-initiated, database-based study that will retrospectively observe the treatment and medication patterns of about 22,500 patients with heart failure from 25 heart failure centers and 25…
- Trial name
- NCT06099028
- Testing
- no intervention
- Where
- China
- Volunteers
- 22,500 people
- Sponsor
- Peking University First Hospital
Heart Failure With Preserved Ejection Fraction
The Impact of Exercise Training on Functional Capacity in Heart Failure
The purpose of this study is to determine whether exercise training will improve functional capacity in patients with heart failure and preserved ejection fraction.
- Trial name
- NCT01288365
- Testing
- Exercise training
- Where
- Israel
- Volunteers
- 80 people
- Sponsor
- Meir Medical Center
Malignant Neoplasm, Leukemia, Lymphocytic, Chronic, B-Cell
Project to Improve Communication About Serious Illness - Pilot Study
This two-year pilot study will test whether a one-page "Jumpstart Form" will affect goals-of-care discussions in the hospital. This form will be provided to clinicians and will include patient-specific information about…
- Conditions
- Malignant Neoplasm, Leukemia, Lymphocytic, Chronic, B-Cell, Lung Disease Chronic, Congestive Heart Failure
- Trial name
- PICSI-P (NCT03746392)
- Testing
- Jumpstart Intervention
- Where
- 2 sites in United States
- Volunteers
- 150 people
- Sponsor
- University of Washington
Heart Failure
Feasibility of Cardiac Rehabilitation in Patients With Heart Failure at the Moi Teaching and Referral Hospital
This is a study to find out whether cardiac rehabilitation is feasible in Western Kenya. This study will test whether cardiac rehabilitation is feasible by measuring how many participants are able to follow and complete two…
- Trial name
- FCR-HF (NCT02795936)
- Testing
- Cardiac rehabilitation
- Where
- Kenya
- Volunteers
- 100 people
- Sponsor
- Duke University
Transthyretin Amyloid Cardiomyopathy (ATTR CM)
CLEOPATTRA: A Research Study to Look at the Effects of Treatment With a Medicine Called Coramitug (NNC6019-0001) in People With Heart Failure Due to Transthyretin Amyloid (ATTR) Amyloidosis
This study will find out if a new medicine called NNC6019-0001 can help reduce the risk of heart-related death and illness in participants with a condition called transthyretin amyloid cardiomyopathy (ATTR-CM), which affects the…
- Trial name
- CLEOPATTRA (NCT07207811)
- Testing
- NNC6019-0001
- Where
- 299 sites in United States, Argentina and 18 more
- Volunteers
- 1,280 people
- Sponsor
- Novo Nordisk A/S
Kidney Transplant; Complications
The EFfect of FinErenone in Kidney TransplantiOn Recipients: The EFFEKTOR Study
EFFEKTOR is a vanguard, multicenter, phase 2 randomized, double blinded, placebo controlled clinical trial to determine the feasibility, tolerability, safety, and efficacy of finerenone in kidney transplant recipients (KTRs).
- Trial name
- NCT06059664
- Testing
- Finerenone Oral Tablet
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of North Carolina, Chapel Hill
Heart Failure
Clinical Performance Evaluation of AQT90 FLEX BNP and NT-proBNP
The AQT90 FLEX B-type Natriuretic Peptide (BNP) and N-terminal pro B-type natriuretic peptide (NT-proBNP) Tests are in vitro diagnostic assays intended as an aid in the diagnosis and assessment of the severity of heart failure in…
- Trial name
- NCT01808872
- Where
- United States
- Volunteers
- 569 people
- Sponsor
- Radiometer Medical ApS
Coronary Artery Disease, Congestive Heart Failure
Prognostic Indicators as Provided by the EPIC ClearView
The objective of this study is to determine whether the finger tip images captured by the EPIC ClearView device, when analyzed via the ClearView software, produce a Response Scale that characterizes trends consistent with known…
- Conditions
- Coronary Artery Disease, Congestive Heart Failure, Valvular Heart Disease, Atrial Fibrillation
- Trial name
- GBMC (NCT01476995)
- Where
- United States
- Volunteers
- 353 people, healthy volunteers welcome
- Sponsor
- Epic Research & Diagnostics, Inc.
Heart Failure
Cardiac Rehabilitation in Patients With Continuous Flow Left Ventricular Assist Devices:Rehab VAD Trial
Cardiac rehabilitation programs improve mortality, functional capacity, and quality of life, for a variety of patients with heart disease.
- Trial name
- RehabVAD (NCT01584895)
- Testing
- Cardiac Rehabilitation
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Henry Ford Health System
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.