Clinical trials: Congestive Heart Failure(CHF)
Lymphedema, Lower Limb, Lymphedema
Detecting the Undetected: Heart Failure Screening at the Lymphoedema Point of Care
Heart failure affects more people than the four most common cancers combined. When identified early, management is more straightforward, preventing complications, hospitalisations, and fatalities.
- Conditions
- Lymphedema, Lower Limb, Lymphedema, Heart Failure, Heart Failure (for Example, Fluid Overload)
- Trial name
- NCT07498868
- Where
- United Kingdom
- Volunteers
- 618 people
- Sponsor
- Swansea Bay University Health Board
Diabetes, Heart Failure
Multipolar CRT-d and Diabetes
Background: Type 2 Diabetes Mellitus (T2DM) is a multi factorial disease, affecting clinical outcomes in failing heart (HF) patients treated by Cardiac Resynchronization Therapy with a defibrillator (CRT-d).
- Conditions
- Diabetes, Heart Failure, Heart Failure NYHA Class II, Heart Failure NYHA Class III
- Trial name
- NCT03095196
- Testing
- Multipolar CRT-d, plus conventional drug therapy for HF., Bipolar CRT-d, plus conventional drug therapy for HF., HF drugs
- Volunteers
- 190 people
- Sponsor
- Celestino Sardu
Arthritis, Cancer
MoveStrong at Home: A Feasibility Study of a Model for Remote Delivery of Functional Strength and Balance Training Combined With Nutrition Education for Older Pre-frail Adults.
Sufficient muscle strength helps to get out of a chair and can prevent falls. Up to 30% of older adults experience age-related loss of muscle strength, which can lead to frailty and health instability.
- Conditions
- Arthritis, Cancer, Cardiovascular Diseases, Chronic Lung Disease
- Trial name
- NCT04663685
- Testing
- Exercise program, Nutrition education
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- University of Waterloo
Heart Failure
Outcomes of Patients With Heart Failure Hospitalized in an Internal Medicine Unit
In 2018, the investigators evaluated the treatment of 236 patients with heart failure (with preserved or reduced ejection fraction) before and after hospitalization in our internal medicine unit (from 2016 to 2017).
- Trial name
- NCT04845126
- Where
- France
- Volunteers
- 236 people
- Sponsor
- University Hospital, Montpellier
Advanced Heart Failure, Left Ventricular Assist Device Implantation
GDF-15 and Early Outcomes After LVAD Implantation
This observational study aims to investigate the association between preoperative GDF-15 levels and early postoperative outcomes in patients undergoing left ventricular assist device (LVAD) implantation.
- Trial name
- LVAD-GDF15 (NCT07497308)
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people
- Sponsor
- Akdeniz University
Heart Failure
Effect of Non-invasive Neurostimulation on Variability OF HEART RATE IN PATIENTS WITH HEART FAILURE.
This study is a clinical trial, and may also be referred to as a "before and after" study, in which all subjects receive the same treatment and their condition is checked before initiation and after various times of treatment.
- Trial name
- HD-tDCS (NCT05944874)
- Testing
- high definition transcranial direct current stimulation
- Where
- Brazil
- Volunteers
- 30 people
- Sponsor
- Federal University of Paraíba
Heart Failure Preserved Ejection Fraction
Coronary Sinus Reducer For The Management Of Symptomatic Heart Failure
The purpose of this study is to evaluate the efficacy of CS Reducer implantation in patients with HFpEF and CMD on left ventricular filling pressures, specifically invasive measurement of PAWP during standardized exercise.
- Trial name
- NCT07057323
- Testing
- Coronary Sinus Reducer
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- Mayo Clinic
Heart Failure
Trial of a Tailored Message Program to Implement CHF Guidelines
Congestive heart failure is a serious health problem in the United States and is associated with excessive morbidity and mortality. Several classes of medications have been shown to improve mortality in patients with CHF.
- Trial name
- NCT00013026
- Testing
- CHF Self-management Education (Web-based Education)
- Where
- United States
- Volunteers
- 700 people, healthy volunteers welcome
- Sponsor
- US Department of Veterans Affairs
Congestive Heart Failure
External Sensors for remoTe MoniToring of Heart Failure Patients With Implantable Defibrillators
This study has been designed to describe the use of Remote Patient Management (RPM) systems equipped with sensors for the measurement of weight and blood pressure in an Italian health care setting, verifying their efficacy and…
- Trial name
- ESTIMATE-HF (NCT02147340)
- Where
- Italy
- Volunteers
- 186 people
- Sponsor
- Maurizio Eugenio Landolina
Chronic Heart Failure
SPECT-based Prediction and Evaluation of CRT Efficacy in CHF
This study evaluates the state of the cardiac sympathetic activity and the severity of ventricular dyssynchrony in chronic heart failure patients and assesses the capabilities of radionuclide indication methods in determining the…
- Trial name
- MIBGinCRT (NCT03667989)
- Testing
- Assessment of cardiac sympathetic innervation by 123I-MIBG
- Where
- Russia
- Volunteers
- 60 people
- Sponsor
- Tomsk National Research Medical Center of the Russian Academy of Sciences
Heart Failure
Impella Pump Return Study to Analyze Deposits and Biomaterial in Used Pumps
Analysis of cell and protein deposits on the Impella Heart Pump.
- Trial name
- NCT06765226
- Where
- 7 sites in Germany
- Volunteers
- 200 people
- Sponsor
- Abiomed Inc.
Heart Failure
Dapagliflozin in Diabetic Patients (Type 2) With Decompensated Heart Failure
We hypothesize that Dapagliflozin could improve the diuretic response in diabetic patients with acute decompensated heart failure owing to its diuretic effect in addition to improvement of blood glucose level without remarkable…
- Trial name
- NCT04385589
- Testing
- Dapagliflozin, insulin
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Assiut University
Heart Failure
Empagliflozin on Patients With Preserved Heart Failure
The proposed research in this application will investigate the effect of empagliflozin on cardiac remodeling in patients with heart failure with preserved ejection fraction.
- Trial name
- NCT07112274
- Testing
- Empagliflozin 10 MG
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Damanhour University
Congestive Heart Failure
Correlation of Intrathoracic Impedance Measures With Blood Plasma Volume in Congestive Heart Failure
Congestive heart failure is a condition in which the heart is weakened and is unable to pump enough blood to the organs of the body to meet the demands of the body.
- Trial name
- Optivol (NCT00603213)
- Testing
- Blood Volume Analysis, Echocardiogram
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Medical University of South Carolina
Heart Failure
Ivabradine in Patients With an Unsatisfactory Percentage of Cardiac Resynchronization Therapy
The purpose of this study is to determine the role of ivabradine in cardiac resynchronization recipients with an unsatisfactory percentage biventricular pacing.
- Trial name
- IvaCRT (NCT02166060)
- Testing
- Ivabradine
- Where
- Poland
- Volunteers
- 60 people
- Sponsor
- Medical University of Warsaw
Ventricular Tachycardia
Exercise Training in ICD Recipients; Effect on Therapy Delivered, Depression and Anxiety
Interventional study in patients with ICD. Controlled, open intervention with exercise training. Assessment of changes in physiological and psychological parameters.
- Trial name
- ETHIC (NCT01038960)
- Testing
- Exercise training
- Where
- Norway
- Volunteers
- 40 people
- Sponsor
- Helse Stavanger HF
Chronic Heart Failure With Reduced Systolic Function
Dapagliflozin Effect on Symptoms and Biomarkers in Patients With Heart Failure
The primary purpose of this study is to evaluate the impact of dapagliflozin, as compared with placebo, on heart failure disease-specific biomarkers, symptoms, health status, and quality of life in patients with chronic heart…
- Trial name
- DEFINE-HF (NCT02653482)
- Testing
- Dapagliflozin
- Where
- 25 sites in United States
- Volunteers
- 263 people
- Sponsor
- Saint Luke's Health System
Heart Failure, Coronary Artery Disease
Maximal Leg Press Strength Training Study for Coronary Artery Disease Patients
Maximal strength training has been shown to increase muscular strength, muscular volume and work economy. An 8 week maximal leg press training regime will be conducted on cardiac heart failure patients to evaluate whether they…
- Trial name
- NCT00184457
- Testing
- Strength training intervention
- Where
- Norway
- Volunteers
- 12 people
- Sponsor
- Norwegian University of Science and Technology
Heart Failure
Sound Heart Spiritual Combined With Dhikr for Patients With Heart Failure
Heart failure can cause persistent fatigue, impaired quality of life, and spiritual distress. This interventional study will evaluate a 12-week Sound Heart Spiritual intervention combined with dhikr (SHS-Zikir) among Muslim…
- Trial name
- SHS-ZIKIR (NCT07795632)
- Testing
- Sound Heart Spiritual Intervention Combined With Dhikr
- Volunteers
- 60 people
- Sponsor
- Risqi Wahyu Susanti
Empagliflozin in Cardiorenal Syndrome Type 1
The Treatment Effects of Empagliflozin on Renal Outcomes in Cardiorenal Syndrome Type 1
Effects of Empagliflozin compared with placebo in cardiorenal syndrome type 1, evaluated by MAKE30.
- Trial name
- TREAT-CRS (NCT06030843)
- Testing
- Empagliflozin 10 MG
- Where
- Thailand
- Volunteers
- 200 people
- Sponsor
- Chulalongkorn University
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