Clinical trials: Congestive Heart Failure, completed
Chronic Heart Failure
Study to Investigate the Effects of Vitamin D Administration on Plasma Renin Activity in Patients With Stable Chronic Heart Failure
The renin-angiotensin system (RAS) is a regulatory system that plays an essential role in patients with chronic heart failure (CHF).
- Trial name
- VitD-CHF (NCT01092130)
- Testing
- Vitamin D
- Where
- Netherlands
- Volunteers
- 101 people
- Sponsor
- University Medical Center Groningen
Heart Failure
Clinical Performance Evaluation of AQT90 FLEX BNP and NT-proBNP
The AQT90 FLEX B-type Natriuretic Peptide (BNP) and N-terminal pro B-type natriuretic peptide (NT-proBNP) Tests are in vitro diagnostic assays intended as an aid in the diagnosis and assessment of the severity of heart failure in…
- Trial name
- NCT01808872
- Where
- United States
- Volunteers
- 569 people
- Sponsor
- Radiometer Medical ApS
Heart Failure
Pilot and Feasibility Study of a MAWDS (Medications, Activity, Weight, Diet and Symptoms) Heart Failure Mobile Platform
The purpose of this study is to create a smartphone app that delivers the educational content of the current Intermountain MAWDS* program and allows patients to enter and track their MAWDS data within the app; and to determine if…
- Trial name
- iMAWDS (NCT03294512)
- Testing
- MAWDS data entry on app
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Intermountain Health Care, Inc.
Shock, Cardiogenic, Heart Failure
Effects of Pyruvate in Patients With Cardiogenic Shock and Intra-aortic Balloon Counterpulsation
Pyruvate is an intermediate of energy metabolism and was shown to possess pronounced positive inotropic effects in vitro and in vivo without altering myocardial oxygen consumption.
- Conditions
- Shock, Cardiogenic, Heart Failure, Acute Myocardial Infarction
- Trial name
- NCT00604331
- Testing
- Pyruvate
- Where
- Germany
- Volunteers
- 8 people
- Sponsor
- Herzzentrum Goettingen
Hyponatremia
THE BALANCE Study: Treatment of Hyponatremia Based on Lixivaptan in NYHA Class III/IV Cardiac Patient Evaluation
The purpose of this study is to determine the safety and efficacy of lixivaptan in the treatment of hyponatremia in patients with congestive heart failure.
- Trial name
- NCT00578695
- Testing
- lixivaptan
- Where
- 287 sites in United States, Argentina and 13 more
- Volunteers
- 652 people
- Sponsor
- CardioKine Inc.
Ventricular Fibrillation, Ventricular Tachycardia
SD01 Registry (SD01 ICD Lead)
This registry is designed to gather further evidence, in addition to the SD01 Master Study, for the safety and efficacy of the SD01 ICD lead.
- Conditions
- Ventricular Fibrillation, Ventricular Tachycardia, Heart Failure
- Trial name
- SD01 Registry (NCT02014675)
- Testing
- SD01 ICD lead
- Where
- 10 sites in Germany
- Volunteers
- 280 people
- Sponsor
- Biotronik SE & Co. KG
Heart Failure, Patient
Web-based Training and Telephone Follow-up of Patients With Heart Failure: Randomized Controlled Trial
Web-based training and telephone monitoring have an effect on reducing symptom burden in patients with heart failure. Web-based training and telephone monitoring have an effect on improving the quality of life of patients with…
- Conditions
- Heart Failure, Patient, Quality of Life, Symptoms
- Trial name
- NCT04210167
- Testing
- web-based training and telephone monitoring
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Akdeniz University
Heart Failure
Cardiac Resynchronization Therapy Defibrillator Based Impedance Monitoring Study
The intent of this feasibility study is to collect and analyze intra-thoracic impedance measurements from a CRT-D device in a heart failure population.
- Trial name
- NCT00500838
- Testing
- Transthoracic Impedance
- Where
- 4 sites in United States
- Volunteers
- 75 people
- Sponsor
- Abbott Medical Devices
Chronic Patients, Heart Failure
Multicenter Trial for the Validation of Vitalera Platform
Vitalera has implemented a cloud platform for the telemonitoring of chronic patients through portable medical devices and an alarm-based system that issues health alerts when a patient's biomedical measurement is outside a…
- Trial name
- VAL-HIC (NCT05825755)
- Testing
- vitalera telemonitoring platform
- Where
- 10 sites in Spain
- Volunteers
- 97 people
- Sponsor
- humanITcare
Heart Failure, Congestive
Telemonitoring in Patients With Heart Failure
The purpose of this study is to investigate if telemonitoring results in a decrease in hospital admissions, with equal quality of care defined as mortality, quality of life and unplanned visits with caregivers.
- Trial name
- TEHAF2 (NCT00502255)
- Testing
- Health Buddy system, Telemonitoring in patients with heart failure
- Where
- 3 sites in Netherlands
- Volunteers
- 382 people
- Sponsor
- Maastricht University Medical Center
Heart Failure With Preserved Ejection Fraction
Efficacy and Safety of LCZ696 Compared to Valsartan, on Morbidity and Mortality in Heart Failure Patients With Preserved Ejection Fraction
The purpose of this study was to evaluate the effect of LCZ696 compared to valsartan in the reduction of cardiovascular death and heart failure(HF) hospitalizations in patients with HF with preserved ejection fraction.
- Trial name
- PARAGON-HF (NCT01920711)
- Testing
- LCZ696, Valsartan
- Where
- 715 sites in United States, Argentina and 41 more
- Volunteers
- 4,822 people
- Sponsor
- Novartis Pharmaceuticals
Congestive Heart Failure, Cardiomyopathy
Cardiac Hormone Replacement With Brain Natriuretic Peptide (BNP) in Heart Failure
The purpose of this study is to determine the effects of subcutaneous injection of Human BNP (nesiritide), a hormone produced by the heart, on the pumping ability of the heart, kidney function, and hormonal function in persons…
- Trial name
- SubqBNP (NCT00252187)
- Testing
- B-type Natriuretic Peptide (BNP)
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Horng Chen
Heart Failure With Preserved Ejection Fraction, Beta Blocker
Carvedilol in HF With Preserved EF
Beta-blockers improve clinical outcomes in heart failure and reduced ejection fraction (HFrEF); but not in those with preserved EF.
- Conditions
- Heart Failure With Preserved Ejection Fraction, Beta Blocker, Myocardial Strain
- Trial name
- NCT05553314
- Testing
- Carvedilol
- Where
- 2 sites in South Korea
- Volunteers
- 63 people
- Sponsor
- Seoul National University Bundang Hospital
Heart Failure
Aspirin Withdrawal in Non-ischaemic Cardiomyopathy Study
Heart failure (cardiomyopathy) is a chronic condition in which the heart fails to function as a pump to move blood around the body.
- Trial name
- NCT01534026
- Testing
- Aspirin, withdrawal of aspirin
- Where
- Australia
- Volunteers
- 12 people
- Sponsor
- The Alfred
Heart Failure
Provider Notification for High B-type Natriuretic Peptide Values
This proposal examines use of a clinical reminder to the primary provider of patient with a high B type natriuretic peptide but no prior imaging.
- Trial name
- NCT01734135
- Testing
- Clinical Reminder
- Where
- United States
- Volunteers
- 115 people
- Sponsor
- VA Palo Alto Health Care System
Heart Failure, Atrial Fibrillation
Cardiac Resynchronisation Therapy and AV Nodal Ablation Trial in Atrial Fibrillation Patients (CAAN-AF)
Cardiac resynchronization therapy (CRT) is a treatment for heart failure in patients who also suffer from ventricular dyssynchrony, a form of uncoordinated contraction of the ventricle (lower pumping chamber of the heart).
- Trial name
- CAAN-AF (NCT01522898)
- Testing
- AV nodal ablation, Medical Ventricular Rate Control
- Where
- 33 sites in Australia, Germany and 3 more
- Volunteers
- 145 people
- Sponsor
- University of Adelaide
Heart Failure
Assessment of Digital Consultations on Clinical Impact and Efficiency
Healthcare workers have a high workload as compared to other sectors and this burden is projected to increase due to an aging society.
- Trial name
- ADMINISTER (NCT05413447)
- Testing
- Digital consult
- Where
- 5 sites in Netherlands
- Volunteers
- 150 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Congestive Heart Failure
Validating PROMIS Instruments in Congestive Heart Failure Patients Receiving a Heart Transplant
The Patient-Reported Outcomes Measurement Information System (PROMIS) is an NIH Roadmap initiative to develop a computerized system measuring patient-reported outcomes in respondents with a wide range of chronic diseases and…
- Trial name
- NCT00783848
- Where
- 2 sites in United States
- Volunteers
- 58 people
- Sponsor
- Duke University
Congestive Heart Failure
Extracorporeal Shockwave Myocardial Revascularization (ESMR) Therapy For The Treatment of Chronic Heart Failure
Evaluation of non-invasive treatment modality, using low-intensity extracorporeal shockwaves for treatment of subjects diagnosed with Congestive Heart Failure, with ischemic etiology.
- Trial name
- NCT01251185
- Testing
- Cardiospec
- Where
- Israel
- Volunteers
- 9 people
- Sponsor
- Medispec
Arrhythmia, Cardiovascular Diseases
Diagnostic Investigation of Sudden Cardiac Event Risk
The overall objective of the DISCERN study is to develop and validate a genomic diagnostic assay to identify patients at increased risk for lethal ventricular arrhythmias and sudden cardiac death (SCD).
- Conditions
- Arrhythmia, Cardiovascular Diseases, Heart Failure, CVD
- Trial name
- DISCERN (NCT00500708)
- Where
- 8 sites in United States
- Volunteers
- 1,564 people
- Sponsor
- CardioDx
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