Clinical trials: Congestive Heart Failure, completed
Heart Failure
Effect of a Virtually Implemented Cardiac Rehabilitation Program
A clinical trial investigating the effects of a virtually implemented home-based cardiac rehab program with real-time, video based exercise supervision and vitals monitoring.
- Trial name
- VIRT-CR (NCT05201976)
- Testing
- Virtually administered Cardiac Rehab program, Standard of Care in person Cardiac Rehab Program
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- University of Pennsylvania
Heart Failure
Heart Failure Re-admission Risk Estimation Using NICaS System With Comparison to Serum BNP Levels
HF represents a major burden in the developed world. Mortality and rehospitalization rates post-discharge in patients admitted with HF may be as high as 15%-30% within 60-90 days, respectively.
- Trial name
- NCT01765335
- Testing
- NICaS system
- Where
- Israel
- Volunteers
- 20 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Heart Failure, Cohort Study
Observational Usage and Efficacy Study of Candesartan in Heart Failure Treatment in France
The purpose of this study is to describe the way candesartan is used in heart failure treatment in France (treatment initiation and monitoring), treatment stops occurrence and reasons for and patients clinical evolution
- Trial name
- SISTOLA (NCT00679640)
- Testing
- Candesartan
- Where
- 103 sites in France
- Volunteers
- 450 people
- Sponsor
- AstraZeneca
Heart Failure, Atrial Fibrillation
CONTAK RENEWAL 3 AVT
The RENEWAL 3 AVT device is designed to treat patients suffering from HF, with a history of or at risk of developing atrial and ventricular arrhythmias
- Trial name
- NCT00158977
- Testing
- CONTAK RENEWAL 3 AVT
- Where
- United States
- Volunteers
- 73 people
- Sponsor
- Boston Scientific Corporation
Heart Failure, Ventricular Arrhythmias and Cardiac Arrest
Effects of Upgrading From Right Ventricular Pacing to Cardiac Resynchronization Therapy and Comparison With Dual-Chamber Defibrillator
Patients who consecutively underwent de novo CRT implantation, CRT upgrade, and DDDR ICD implantation at the Cardiology Clinic of Bursa Postgraduate Hospital between January 2019 and December 2023 according to the European…
- Trial name
- NCT07077928
- Testing
- Pacemaker upgrade
- Where
- Turkey (Türkiye)
- Volunteers
- 307 people
- Sponsor
- Bursa Postgraduate Hospital
Heart Failure
A Study to Observe Treatment Patterns in Patients in Colombia Who Have Heart Failure
Researchers want to learn more about the treatments doctors choose to treat heart failure. Heart failure means the heart isn't pumping as well as it should be.
- Trial name
- HEATCO (NCT05036967)
- Testing
- HF medication
- Where
- Colombia
- Volunteers
- 1,000 people
- Sponsor
- Bayer
Heart Failure, Diastolic
Mechanisms of Exercise Intolerance in Heart Failure With Preserved Ejection Fraction
The global objective of this study is to determine the mechanisms of exercise intolerance and dyspnea on exertion (DOE) in patients with HFpEF and based on this pathophysiology, test whether specific exercise training programs…
- Trial name
- NCT04068844
- Testing
- Exercise training
- Where
- United States
- Volunteers
- 93 people
- Sponsor
- University of Texas Southwestern Medical Center
Cardiovascular Disease
Absolute Bioavailability and ADME Study of [14C]AZD9977 in Healthy Male Subjects
Study to Assess the Absorption, Metabolism, and Excretion of [14C]AZD9977 after a Single-Dose Oral Administration
- Trial name
- NCT04686591
- Testing
- AZD9977 capsule 50 mg, [14C]AZD9977 Solution for Infusion, 20 µg/mL (NMT 37.0 kBq/5 mL), [14C]AZD9977 Oral Suspension, 100 mg (NMT 9.9 MBq)
- Where
- United Kingdom
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Congestive Heart Failure
Safety and Efficacy Study of Carvedilol to Treat Children With Congestive Heart Failure
The purpose of this study is to determine whether a new medicine, called carvedilol, improves symptoms and heart function in children who have congestive heart failure (diminished function of their heart muscle that pumps blood…
- Trial name
- NCT00052026
- Testing
- carvedilol
- Where
- 21 sites in United States
- Volunteers
- 161 people
- Sponsor
- Shaddy, Robert, M.D.
Heart Failure, Systolic, Heart Failure, Diastolic
Physiological Signals, Activity and Posture for Surface Mounted Insertable Cardiac Monitor in Heart Failure Study
To characterize the physiological signals collected from a Wearable Cardiac Monitor (WCM) prototype device in subjects with heart failure and preserved ejection fraction (HFpEF) and compare against signals from subjects with…
- Trial name
- HAPI-HF (NCT04112576)
- Testing
- Wearable cardiac monitor
- Where
- 3 sites in United States, Singapore and 1 more
- Volunteers
- 100 people
- Sponsor
- Boston Scientific Corporation
Hypertension, Diabetes Mellitus, Type 2
ENCOMPASS: Expansion Study B, RCT
Some patients living with multiple long-term health conditions have difficulty accessing the services they need, despite available primary care and community resources.
- Conditions
- Hypertension, Diabetes Mellitus, Type 2, Chronic Kidney Diseases, Ischemic Heart Disease
- Trial name
- ENCOMPASS (NCT04790617)
- Testing
- Community Health Navigator Program
- Where
- Canada
- Volunteers
- 183 people
- Sponsor
- University of Calgary
Heart Failure, Diabetes Mellitus
DPP-4 Inhibitor and Serum BNP Level of Diabetic Patients With Congestive Heart Failure
We thought to investigate the influence of DPP-4 inhibitor on the serum BNP level of diabetic patients with congestive heart failure. This study consists of two protocols.
- Trial name
- NCT02312427
- Testing
- Suspending DPP-4 inhibitor, in outpatient service, Starting DPP-4 inhibitor after treatment of heart failure, Suspending DPP-4 inhibitor after treatment of heart failure
- Where
- Japan
- Volunteers
- 10 people
- Sponsor
- Mitsui Memorial Hospital
Chronic Heart Failure
Hawthorn Extract Randomized Blinded Chronic Heart Failure (HERB CHF) Trial
To determine the effect of hawthorn extract 450 mg bid vs. placebo, in addition to standard medical therapy in ambulatory patients with NYHA class II to IV chronic heart failure on submaximal exercise as measured by the 6-minute…
- Trial name
- NCT00343902
- Testing
- Crataegus Special Extract WS 1442
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- National Center for Complementary and Integrative Health (NCCIH)
Cardiorenal Syndrome, Acute Decompensated Heart Failure
Biomonitoring and Cardiorenal Syndrome in Heart Failure(BIONICS-HF) Trial
The purpose of this study is to evaluate the ability of a non-invasive monitor that measures how much fluid is in the body as well as various blood tests for their ability to predict worsening kidney function in patients with…
- Trial name
- BIONICS-HF (NCT01570153)
- Where
- 2 sites in United States, Italy
- Volunteers
- 100 people
- Sponsor
- Massachusetts General Hospital
Heart Failure
Role of Sacubitril/Valsartan in Improving Provider Performance in Managing Heart Failure Under Medicare Alternative Payment Models
This study evaluated the association between sacubitril/valsartan utilization and HF patients' Part A \& B expenditures within the reimbursement framework of BPCI and MSSP, and identified BPCI/MSSP participants with the greatest…
- Trial name
- NCT05096039
- Testing
- Sacubitril/valsartan, ACEI or ARB and no sacubitril/valsartan
- Where
- United States
- Volunteers
- 1,614,719 people
- Sponsor
- Novartis Pharmaceuticals
Heart Failure
Right Ventricular Function and Exercise Capacity in Patients With Continuous-flow Left Ventricular Assist Devices
Exercise capacity in continous-flow left ventricular assist device (CF-LVAD) patients remains severely reduced post-implant. While the effect of right ventricular (RV) failure early after pump implantation, and its effect on…
- Trial name
- NCT02658136
- Testing
- Cardiac Computed tomography
- Where
- Denmark
- Volunteers
- 15 people
- Sponsor
- Finn Gustafsson
Chronic Heart Failure
Left Bundle Branch Pacing Versus Biventricular Pacing for Cardiac Resynchronization Therapy
The present study will recruit 40 symptomatic heart failure patients with left ventricular ejection fraction (LVEF) below 35% and complete left bundle branch block(QRSd≥130 ms).
- Trial name
- LBBP-RESYNC (NCT04110431)
- Testing
- Left bundle branch pacing, Biventricular pacing
- Where
- 2 sites in China
- Volunteers
- 40 people
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
Chronic Heart Failure
Telemedical Interventional Management in Heart Failure II
Superiority of additional Remote Patient Management (RPM) in patients with chronic heart failure (CHF) in comparison to usual care in terms of, e.g.: days lost due to unplanned cardiovascular hospitalization or death all-cause…
- Trial name
- TIM-HF2 (NCT01878630)
- Testing
- Remote Patient Management, Usual Care
- Where
- 109 sites in Germany
- Volunteers
- 1,571 people
- Sponsor
- Charite University, Berlin, Germany
Heart Failure
A Strategy of Home Telehealth for Management of Congestive Heart Failure(STARTEL)
To demonstrate the safety, feasibility, quality of life, primary caregiver satisfaction, and cost effectiveness of integrated Home Telehealth care versus standard care in a heart failure clinic.
- Trial name
- NCT00247000
- Testing
- Routine Care in a HF clinic vs Home Telehealth Care for HF
- Where
- Canada
- Volunteers
- 150 people
- Sponsor
- Nova Scotia Health Authority
Chronic Heart Failure, Reconditioning to Effort
Evaluation of the Effects of Eccentric Muscle Training Versus Conventional Concentric Training in Chronic Heart Failure
This is a single-centre open randomized parallel-group study. Patients will be selected at random to be included in group 1: eccentric rehabilitation or group 2: conventional rehabilitation.
- Trial name
- NCT02046707
- Testing
- initial evaluation, Period of cardiac rehabilitation, final evaluation
- Where
- France
- Volunteers
- 71 people
- Sponsor
- Centre Hospitalier Universitaire Dijon
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