Clinical trials: Congestive Heart Failure, completed
Locally Advanced Cancer, Metastatic Cancer
Identification of In-hospital Patients in Need of Palliative Care Using a New Simplified Screening Tool
Every day many patients affected by chronic life-limiting illnesses are admitted into Internal Medicine wards, coming from the Emergency Department.
- Conditions
- Locally Advanced Cancer, Metastatic Cancer, Chronic Respiratory Failure, Chronic Heart Failure
- Trial name
- SST2017 (NCT04143230)
- Testing
- Screening for PC by means of two different screening tools
- Where
- Italy
- Volunteers
- 660 people
- Sponsor
- A.O.U. Città della Salute e della Scienza
Heart Failure, Congestive
Reversal of Ventricular Remodeling With Toprol-XL
The purpose of this study is to determine whether treatment with Toprol-XL for 12 months in asymptomatic heart failure subjects will improve their heart structure and thus prevent the progression to symptomatic disease.
- Trial name
- NCT00038077
- Testing
- Seloken ZOK/Toprol-XL
- Where
- 44 sites in United States
- Volunteers
- 300 people
- Sponsor
- AstraZeneca
Congestive Heart Failure
Breathing Relaxation Exercise Heart Failure
The aim of the study is to determine the effect of breathing and relaxation exercises on dyspnea, fatigue and self-care level in heart failure patients.
- Trial name
- NCT05905627
- Testing
- exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 65 people
- Sponsor
- University of Yalova
Diabetes Mellitus, Type 2, Cardiovascular Diseases
A Study for Comparison of Canagliflozin Versus Alternative Antihyperglycemic Treatments on Risk of Heart Failure Hospitalization and Amputation for Participants With Type 2 Diabetes Mellitus and the Subpopulation With Established Cardiovascular Disease
The primary purpose of study is to estimate the incidence and comparative effect on health outcomes: 1) hospitalization for heart failure, 2) below knee lower extremity amputation.
- Trial name
- NCT03492580
- Testing
- Canagliflozin, Empagliflozin, Dapagliflozin
- Where
- United States
- Volunteers
- 714,582 people
- Sponsor
- Janssen Research & Development, LLC
Heart Failure
Effects of Implementing a High Potassium Diet in Heart Failure Patients
This study evaluates the safety and physiologic effects of increasing dietary potassium intake in individuals with heart failure.
- Trial name
- NCT03059680
- Testing
- High potassium diet
- Volunteers
- 30 people
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Diabetes, Heart Failure
Multipolar CRT-d and Diabetes
Background: Type 2 Diabetes Mellitus (T2DM) is a multi factorial disease, affecting clinical outcomes in failing heart (HF) patients treated by Cardiac Resynchronization Therapy with a defibrillator (CRT-d).
- Conditions
- Diabetes, Heart Failure, Heart Failure NYHA Class II, Heart Failure NYHA Class III
- Trial name
- NCT03095196
- Testing
- Multipolar CRT-d, plus conventional drug therapy for HF., Bipolar CRT-d, plus conventional drug therapy for HF., HF drugs
- Volunteers
- 190 people
- Sponsor
- Celestino Sardu
Coronary Arteriosclerosis, Heart Failure, Congestive
Evaluation of Myocardial Viability by Means of Low-dose Dobutamine Gated SPECT (the DOGS Study)
Viability assessment remains a clinical challenge in patient with coronary artery disease and left ventricular dysfunction. Several imaging modalities are available for evaluating myocardial viability, based either on perfusion…
- Conditions
- Coronary Arteriosclerosis, Heart Failure, Congestive, Myocardial Infarction, Myocardial Ischemia
- Trial name
- NCT00213746
- Where
- 8 sites in Belgium, France
- Volunteers
- 75 people
- Sponsor
- University Hospital, Rouen
Heart Failure; With Decompensation
Dynamic Thoracic Impedance as a Marker for Heart Failure Decompensation
This pilot study proposes to perform measurements of approved thoracic impedance technology that will help answer questions in patients with decompensated heart failure.
- Trial name
- NCT02134379
- Testing
- Medtronic ICDs, CRT-Ds, and CRT-Ps
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Charles Porter, MD
Heart Failure
Cardiac Resynchronization Therapy (CRT) Efficacy Study
The aim of this research study is the invasive evaluation of CR therapy efficacy in patients treated with an InSync Sentry device using an external monitoring device to obtain important cardiac parameters.
- Trial name
- NCT00822146
- Testing
- CRT
- Where
- Germany
- Volunteers
- 9 people
- Sponsor
- Medtronic Cardiac Rhythm and Heart Failure
Heart Failure, Ventricular Dysfunction
B-Left HF: Biventricular Versus Left Univentricular Pacing With Implantable Cardiac Defibrillator (ICD) Back-Up in Heart Failure Patients
The purpose of this study is to demonstrate that biventricular pacing (BiV) and left univentricular (left ventricular [LV] only) pacing are safe and effective for cardiac resynchronization therapy in heart failure patients…
- Conditions
- Heart Failure, Ventricular Dysfunction, Heart Diseases
- Trial name
- NCT00187213
- Testing
- Cardiac Resynchronization Therapy
- Where
- France
- Sponsor
- Abbott Medical Devices
Heart Failure
Heart Failure Evaluation Study
Heart failure (HF) is a highly prevalent conditions that impose a significant burden to the patients, the hospital and the healthcare system. In Hong Kong, HF was one of the commonest causes of hospitalization and death.
- Trial name
- NCT05583513
- Testing
- MLHFQ (Minnesota Living with Heart Failure Questionnaire), KCCQ (the Kansas City Cardiomyopathy Questionnaire)
- Where
- Hong Kong
- Volunteers
- 500 people
- Sponsor
- Chinese University of Hong Kong
Kidney Failure, Chronic, Kidney Failure, Acute
Sodium Chloride and Contrast Nephropathy
This phase II, open, non-inferiority, randomized and controlled clinical trial is aimed to ascertain the incidence of contrast nephropathy in outpatients undergoing CT scan with contrast.
- Conditions
- Kidney Failure, Chronic, Kidney Failure, Acute, Heart Failure, Diabetes
- Trial name
- PNIC-Na (NCT03476460)
- Testing
- Oral sodium chloride, Intravenous sodium chloride
- Where
- Spain
- Volunteers
- 271 people
- Sponsor
- Hospital Universitario Ramon y Cajal
Heart Failure
Antiremodeling Effect Of Aldosterone Receptors Blockade With Canrenone In Mild Chronic Heart Failure. AREA IN-CHF Study
The RALES study has shown that spironolactone reduces the risk of morbidity and mortality both from progressive heart failure and sudden death, in patients with NYHA III or IV heart failure.
- Trial name
- NCT00403910
- Testing
- Canrenone
- Where
- 45 sites in Italy
- Volunteers
- 500 people
- Sponsor
- Heart Care Foundation
Heart Failure
REDUCE LAP-HF TRIAL
The objective of this clinical study is to evaluate the safety and performance of the IASD System II in the treatment of heart failure patients with elevated left atrial pressure, who remain symptomatic despite appropriate…
- Trial name
- REDUCE LAP-HF (NCT01913613)
- Testing
- IASD
- Where
- 26 sites in Australia, Austria and 9 more
- Volunteers
- 64 people
- Sponsor
- Corvia Medical
Acute Decompensated Heart Failure
Point Of Care With Serial NT-proBNP Measurement in Patients With Acute Decompensation of Heart Failure
The goal of this study is to explore whether the availability of serial NT-proBNP measurements together with safety parameters such as electrolytes and creatinine may influence treatment decision in patients with acute…
- Trial name
- NCT04471610
- Testing
- Serial measurements of NT-pro BNP, potassium, sodium, and creatinine every second business day
- Where
- Switzerland
- Volunteers
- 52 people
- Sponsor
- Prof. Dr. Jörg Leuppi
Heart Failure
Improvement of a Digital Health Platform for Remote Monitoring of Patients With Heart Failure
In the present project, we propose to run an observational study in order to create a huge dataset with telemonitoring data from heart failure (HF) patients.
- Trial name
- DHEART (NCT05708846)
- Testing
- Telemonitoring
- Where
- 7 sites in Romania, Spain
- Volunteers
- 154 people
- Sponsor
- humanITcare
Acute Decompensated Heart Failure
Assessment of Biomarkers and Cardiorenal Syndrome in Acute Decompensated Heart Failure With Vasodilator Therapy
The purpose of this study is to determine whether Nesiritide is more effective than nitroglycerin in modifying inflammatory and neurohormonal biomarkers without renal toxicity when proper infusion duration is administered.
- Trial name
- ABC-HFT (NCT00842023)
- Testing
- Nesiritide, Nitroglycerin
- Where
- United States
- Volunteers
- 89 people
- Sponsor
- Western University of Health Sciences
Cardiovascular Diseases, Coronary Disease
Dobutamine Echocardiography In Patients With Ischemic Heart Failure Evaluated for Revascularization
To define the role of the assessment of myocardial viability with dobutamine echocardiography (DE) in the clinical evaluation and selection of the best treatment for a high-risk subset of patients with coronary artery disease.
- Conditions
- Cardiovascular Diseases, Coronary Disease, Heart Failure, Heart Failure, Congestive
- Trial name
- DECIPHER (NCT00074724)
- Testing
- Coronary Artery Bypass, Modern medical management, Dobutamine echocardiography
- Volunteers
- 319 people
- Sponsor
- Medstar Health Research Institute
Decompensated Heart Failure
Mechanism and Effects of Manipulating Chloride Homeostasis in Stable Heart Failure
This study is designed to investigate the quantitative effects of sodium-free chloride supplementation on electrolyte balance, volume status, and sodium avidity in stable heart failure patients in a highly controlled environment.
- Trial name
- NCT03440970
- Testing
- Lysine Chloride
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Yale University
Heart Failure, Heart Failure With Preserved Ejection Fraction (HFPEF)
Sodium-Glucose Cotransporter 2 Inhibitor Use in a National Heart Failure Telemonitoring Program
This observational cohort study evaluates temporal trends and determinants of sodium-glucose cotransporter 2 inhibitor (SGLT2i) prescriptions among adults with chronic heart failure enrolled in a nationwide remote monitoring…
- Conditions
- Heart Failure, Heart Failure With Preserved Ejection Fraction (HFPEF), Heart Failure With Reduced Ejection Fraction, Heart Failure With Mildly Reduced Ejection Fraction (HFmrEF)
- Trial name
- REMOTE-HF (NCT07022379)
- Testing
- SGLT2 Inhibitor Use
- Where
- France
- Volunteers
- 13,660 people
- Sponsor
- Satelia
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