Clinical trials: Congestive Heart Failure
Chronic Disease, Diabetes Mellitus
Social Risk Score, Clinical Decision Support Tool and Closed Loop Referral for Social Risk Screen and Referral
The overarching goal of this project is to leverage health information technology (HIT) to integrate available digital information on social needs to improve care for racial and ethnic minorities and socially disadvantaged…
- Conditions
- Chronic Disease, Diabetes Mellitus, Hypertension, Congestive Heart Failure
- Trial name
- NCT05574699
- Testing
- Social Risk Score and CDS Tool, Standard of Care
- Where
- 5 sites in United States
- Volunteers
- 251 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
End Stage Chronic Renal Failure, Congestive Heart Failure (CHF)
The FILTRATE Trial: High-Rate Ultrafiltration for Intravascular Congestion
The purpose of this study is to evaluate whether a personalized, high-rate fluid removal strategy guided by ultrasound is as safe and effective as the standard fluid removal rate for patients with advanced kidney disease who are…
- Conditions
- End Stage Chronic Renal Failure, Congestive Heart Failure (CHF), Intravascular Congestion, Fluid Overload
- Trial name
- FILTRATE (NCT07705269)
- Testing
- High-rate ultrafiltration, Standard fluid removal
- Where
- Mexico
- Volunteers
- 70 people
- Sponsor
- Universidad Autonoma de Nuevo Leon
Congestive Heart Failure(CHF), Pulmonary Edema
Evaluating the Use of Prehospital Lung Ultrasound in EMS: A Multicenter Pilot Study
The goal of this prospective nonrandomized study is to determine if prehospital lung ultrasound findings result in a change in patient management.
- Trial name
- NCT07549334
- Testing
- Pulmonary ultrasound
- Where
- 2 sites in United States
- Volunteers
- 1,000 people
- Sponsor
- Rutgers, The State University of New Jersey
Heart Failure and Reduced Ejection Fraction, Heart Failure Chronic
RELIEVE-HFrEF TRIAL: REducing Lung congestIon Symptoms Using the v-wavE Shunt in adVancEd Heart Failure With Reduced EF
This study will evaluate the V-Wave Ventura Interatrial shunt. The Shunt is a small, hourglass-shaped device implanted in the dividing wall (septum) between the right and left atria (top chambers) of the heart placed during a…
- Conditions
- Heart Failure and Reduced Ejection Fraction, Heart Failure Chronic, Heart Failure New York Heart Association Class III, Heart Failure Congestive
- Trial name
- RELIEVE-HFrEF (NCT07696975)
- Testing
- Implantation of the V-Wave Interatrial shunt
- Volunteers
- 250 people
- Sponsor
- V-Wave Ltd
Heart Failure, Congestive Heart Failure
Care Transitions App for Patients With Multiple Chronic Conditions
The objective of this study is to widely implement and evaluate the Care Transitions App in a randomized controlled trial. The app the investigators designed for patients with multiple chronic conditions has four envisioned…
- Conditions
- Heart Failure, Congestive Heart Failure, Diabetes, Diabetes Mellitus
- Trial name
- NCT06051058
- Testing
- Care Transitions App
- Where
- United States
- Volunteers
- 798 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
CHF - Congestive Heart Failure, COPD
Transitional Care Model Evaluation 2020
The study is a randomized controlled trial to estimate the effects of the transitional care model (TCM) on hospital admissions and patients' experience during the year following the patient's qualifying discharge.
- Conditions
- CHF - Congestive Heart Failure, COPD, Pneumonia
- Trial name
- TCM2020 (NCT04212962)
- Testing
- Transitional care model (TCM), Usual care
- Where
- United States
- Volunteers
- 962 people
- Sponsor
- Mathematica Policy Research, Inc.
Congestive Heart Failure Treated, Myocardial Infarction (MI)
Health Coaching for Patients With Cardiovascular Disease
For patients discharged with a diagnosis of cardiovascular disease coronary artery disease resulting in myocardial infarction and/or congestive heart failure, this study will evaluate if the addition of 12 virtual health coaching…
- Conditions
- Congestive Heart Failure Treated, Myocardial Infarction (MI), Coronary Artery Disease, Congestive Heart Failure Chronic
- Trial name
- NCT06904144
- Testing
- Health Coaching
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Ohio State University
Heart Failure, Congestive, Renal Failure Acute Chronic
Effect of a Focused Point-of-care Ultrasonography Screening Protocol in Hospitalized Patients
This research project aims to establish a real-time focused ultrasound examination protocol for routine assessment of hospitalized patients, including evaluations of the inferior vena cava (IVC), pericardial effusion…
- Conditions
- Heart Failure, Congestive, Renal Failure Acute Chronic, Liver Cirrhosis, Sepsis
- Trial name
- NCT07656428
- Where
- Taiwan
- Volunteers
- 9,000 people
- Sponsor
- National Taiwan University Hospital
Congestive Heart Failure
Plasma ExtrAcellular RNAs and Biomarkers of Heart FaiLure During Decongestion: PEARL-HF Study
The primary objective is to measure the association between extracellular RNA (ex-RNA) levels in plasma in patients receiving aggressive outpatient therapy for CHF with (1) cardiac remodeling and (2) cardiovascular events.
- Trial name
- PEARL-HF (NCT02632656)
- Testing
- Monitoring on heart failure therapy
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- Massachusetts General Hospital
Congestive Heart Failure, Congestive Heart Failure(CHF)
Palliative Care for People With HF
Imagine having heart failure, a condition where the heart struggles to pump blood, making daily life hard. People with heart failure often don't feel well and end up going to the hospital a lot.
- Conditions
- Congestive Heart Failure, Congestive Heart Failure(CHF), Congestive Heart Failure (CHF), Congestive Heart Failure Chronic
- Trial name
- NCT07356843
- Testing
- ADAPT
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Indiana University
Heart Failure，Congestive, Mental Health (Depression)
Evaluation of Nurse-led Integrated Care of Complex Patients Facilitated By Telemonitoring: The SMaRT Study
In Canada, 3 out of 4 Canadians aged 65 and older have at least one chronic condition, while 1 in 4 seniors reported having three or more.
- Conditions
- Heart Failure，Congestive, Mental Health (Depression), Diabetes Mellitus, Chronic Obstructive Pulmonary Disease
- Trial name
- NCT05543720
- Testing
- Medly
- Where
- 4 sites in Canada
- Volunteers
- 350 people
- Sponsor
- University Health Network, Toronto
Pneumonia, Syncope
Quasi-Randomized Evaluation of the UCLA Next Day Clinic (NDC)
The Next Day Clinic (NDC) is a quality improvement initiative that will be launched and operated by UCLA Health starting July 22, 2024. Its goals are to improve patient care and safety and to maximize cost effectiveness.
- Conditions
- Pneumonia, Syncope, Congestive Heart Failure, Cellulitis
- Trial name
- NDC (NCT06526884)
- Testing
- Next Day Clinic
- Where
- United States
- Volunteers
- 570 people
- Sponsor
- University of California, Los Angeles
CHF - Congestive Heart Failure
A Prospective, Randomized, Blind, Controlled Multicenter Clinical Study Comparing the Effectiveness of Preventive Ventricular Arrhythmia Ablation on the Prognosis After Left Ventricular Assist Device (LVAD) Surgery.
To compare the preventive effect of preventive ventricular arrhythmia ablation on the composite events 30 days after surgery in the study population.
- Trial name
- PAVA-LVAD (NCT07589738)
- Testing
- preventive ablation group
- Where
- China
- Volunteers
- 90 people
- Sponsor
- The First Affiliated Hospital of Anhui Medical University
Pediatric Congestive Heart Failure, Congestive Heart Failure
A Clinical Study Used to Estimate Central Venous Pressure Non-invasively Using Occlusion Pressure
The purpose of this study is to collect different measurements using a method called peripheral venous pressure (PVP). PVP checks the pressure in the veins in the arms or legs.
- Trial name
- CV-PRO (NCT07583680)
- Volunteers
- 30 people
- Sponsor
- Le Bonheur Children's Hospital
Heart Failure With Reduced Ejection Fraction (HFrEF), Congestive Heart Failure(CHF)
BIOmarker Based Diagnostic TOOLkit to Personalize Pharmacological Approaches in Congestive Heart Failure
This retrospective study will take advantage of an existing EU-funded dataset, the BIOlogy Study to TAilored Treatment in Chronic Heart Failure (BIOSTAT-CHF), which was designed to identify biomarkers related to the response to…
- Trial name
- NCT07470554
- Where
- Italy
- Volunteers
- 4,254 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Heart Transplant Failure and Rejection, Heart Failure
HEARTBiT: Multi-Marker Blood Test for Acute Cardiac Transplant Rejection
Heart transplantation is a life saving therapy for people with end stage heart failure. Acute rejection, a process where the immune system recognizes the transplanted heart as foreign and mounts a response against it, remains a…
- Conditions
- Heart Transplant Failure and Rejection, Heart Failure, Heart Diseases, Heart Failure，Congestive
- Trial name
- HEARTBiT (NCT03575910)
- Where
- 4 sites in United States, Canada
- Volunteers
- 196 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Heart Disease, Congestive Heart Failure
Resynchronization/Defibrillation for Ambulatory Heart Failure Trial in Patients With Permanent Atrial Fibrillation
Atrial fibrillation (AF) and heart failure (HF) are two common heart conditions that are encountered with an increase in death and suffering.
- Conditions
- Heart Disease, Congestive Heart Failure, Atrial Fibrillation
- Trial name
- RAFT-PermAF (NCT01994252)
- Testing
- Optimal Medical therapy plus ICD, Optimal Medical therapy plus CRT/ICD
- Where
- 15 sites in Canada
- Volunteers
- 200 people
- Sponsor
- Ottawa Heart Institute Research Corporation
Congestive Heart Failure(CHF), Pleural Effusion Due to Congestive Heart Failure
DRAIN: DRainage in Acute Decompensated Heart faIlure With Pleural effusioNs
The goal of this study is to assess if removal of fluid around the lungs (pleural effusion) by a routine procedure called as thoracentesis is helpful to decrease shortness of breath in hospitalized patients with congestive heart…
- Trial name
- DRAIN-IT (NCT07419360)
- Testing
- Thoracentesis
- Where
- United States
- Volunteers
- 216 people
- Sponsor
- Albany Medical College
Pulmonary Hypertension, Congestive Heart Failure(CHF)
Observational Study of Patients Undergoing Diagnostic Right Heart Catheterization
The objective of this observational pilot study is to collect HemoCept device data from subjects undergoing diagnostic right heart catheterization (RHC) procedures.
- Conditions
- Pulmonary Hypertension, Congestive Heart Failure(CHF), Valve Disease, Heart
- Trial name
- NCT07224906
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- HemoCept Inc.
Acute on Chronic Systolic Congestive Heart Failure, Cardiorenal Syndrome
Feasibility of the SCD in Cardiorenal Syndrome Patients Awaiting LVAD
Cardiovascular disease is the leading cause of mortality in the US, accounting for 45% of all deaths. Chronic Heart Failure (CHF) is now understood to be a multi-system disease process involving not only the cardiovascular system…
- Trial name
- NEUTRALIZE-CRS (NCT03836482)
- Testing
- Selective Cytopheretic Device
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- SeaStar Medical