Clinical trials: Congestive Heart Failure, completed
Atrial Fibrillation, Heart Failure
Effectiveness of Oral Anticoagulants in Elderly Patients With Non-Valvular Atrial Fibrillation and Heart Failure
Observational study of elderly individuals diagnosed with Non-Valvular Atrial Fibrillation and Heart Failure who are beginning oral blood thinners
- Trial name
- NCT03508271
- Testing
- Non-Interventional
- Where
- United States
- Volunteers
- 60,000 people
- Sponsor
- Bristol-Myers Squibb
Congestive Heart Failure, Heart Failure
Insulin Resistance : Heart Failure
Whether insulin resistance common among Chronic Heart Failure (CHF) patients in Tayside and identify factors associated with insulin resistance in CHF.
- Trial name
- NCT00486967
- Where
- United Kingdom
- Volunteers
- 147 people, healthy volunteers welcome
- Sponsor
- University of Dundee
Acute Heart Failure
Sodium NItroPrusside Treatment in Acute Heart Failure
The primary objective of this multicentric observational retrospective study is to assess the efficacy and safety of SNP as part of the treatment regimen of AHF patients and to identify predictors of efficacy.
- Trial name
- SNIP-AHF (NCT05027360)
- Testing
- SNP - Sodium Nitroprusside
- Where
- Italy
- Volunteers
- 200 people
- Sponsor
- Niguarda Hospital
Neoplasms, Pulmonary Disease, Chronic Obstructive
Outlook: An Intervention to Improve Quality of Life in Serious Illness
This study will demonstrate whether an end-of-life preparation and completion intervention reduces anxiety, depression, pain and other symptoms and improves functional status, spiritual well-being, and quality of life.
- Conditions
- Neoplasms, Pulmonary Disease, Chronic Obstructive, Heart Failure, Renal Disease
- Trial name
- NCT00939146
- Testing
- Outlook Attention Control, Outlook Intervention
- Where
- United States
- Volunteers
- 154 people
- Sponsor
- Duke University
Heart Failure
Efficacy of the PEAC-IC: a Randomized Controlled Clinical Trial
A randomized parallel single-center clinical trial, blinded for the evaluation of the outcomes and statistical analysis. The current hypothesis is that PEAC-IC will improve self-care behavior, knowledge about heart failure…
- Trial name
- PEAC-IC (NCT05081414)
- Testing
- Program for Teaching Self-Care in HF (PEAC-IC)
- Where
- Brazil
- Volunteers
- 56 people
- Sponsor
- University of Sao Paulo
Heart Failure
Dose Proportionality Study With BAY94-8862 IR (Immediate Release) Tablets
This study should estimate the dose proportionality of BAY94-8862 IR tablets.
- Trial name
- NCT01687920
- Testing
- BAY94-8862 (1.25mg), BAY94-8862 (2.5mg), BAY94-8862 (5mg)
- Where
- Germany
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Bayer
Heart Failure
EMPagliflozin outcomE tRial in Patients With chrOnic heaRt Failure With Preserved Ejection Fraction (EMPEROR-Preserved)
This is a study in adults with chronic heart failure. People with chronic heart failure may need to be hospitalised for their condition. Some people with chronic heart failure may eventually die from their condition.
- Trial name
- NCT03057951
- Testing
- Empagliflozin
- Where
- 619 sites in United States, Argentina and 21 more
- Volunteers
- 5,988 people
- Sponsor
- Boehringer Ingelheim
Heart Failure
Comparative Effects of Aerobic Exercises, Resistance Training and Combined Training on Heart Failure Patients
To compare the effectiveness of aerobic training and resistance training and combined training on heart failure patients.
- Trial name
- NCT04937231
- Testing
- Aerobic exercises, Resistance exercises, Combined training
- Where
- Pakistan
- Volunteers
- 92 people
- Sponsor
- Riphah International University
Heart Failure, Mitral Regurgitation
Montreal Safety and Efficacy of the Percutaneous Transvenous Mitral Annuloplasty Device
Reduction in mitral regurgitation due to safe placement of a PTMA device in the coronary sinus.
- Trial name
- PTOLEMY (NCT00571610)
- Testing
- PTMA (Percutaneous Transvenous Mitral Annuloplasty) Implant
- Where
- Canada
- Volunteers
- 5 people
- Sponsor
- Viacor
Congestive Heart Failure
A Clinical Study Assessing the Potential of Piboserod for the Treatment of Heart Failure
The purpose of this study is to determine whether piboserod, a serotonin-4 receptor antagonist, is effective for the treatment of patients with congestive heart failure.
- Trial name
- NCT00421746
- Testing
- Piboserod
- Where
- 17 sites in Denmark, Norway and 1 more
- Volunteers
- 137 people
- Sponsor
- Bio-Medisinsk Innovasjon
Heart Failure
Leadless Electrocardiogram (ECG) Evaluation Study
The leadless electrocardiogram (LECG) is a new technology incorporated into the Consulta CRT-P to obtain an ECG signal from the Consulta CRT-P similar to a surface ECG obtained from the device programmer (PECG) or an external ECG…
- Trial name
- LECG (NCT01297283)
- Testing
- LECG first, Programmer ECG first
- Where
- France
- Volunteers
- 195 people
- Sponsor
- Medtronic Cardiac Rhythm and Heart Failure
Acute Heart Failure
Study of Safety, Tolerability and Pharmacokinetics of Serelaxin in Japanese Acute Heart Failure (AHF) Patients
This is a multicenter, randomized, double-blind, placebo-controlled study to assess safety, tolerability and pharmacokinetics and to explore efficacy of IV infusion of 10 µg/kg/day and 30 µg/kg/day serelaxin for 48 hours compared…
- Trial name
- NCT02002702
- Testing
- Serelaxin
- Where
- 15 sites in Japan
- Volunteers
- 46 people
- Sponsor
- Novartis Pharmaceuticals
Heart Failure, Systolic, Iron Deficiency
Intravenous Iron in paTients With Heart failURe and Reduced Ejection fracTion (HFREF) pLus Iron dEficiency
Effects of ferric carboxymaltose single HD (1000 mg) infusion upon FGF23 in patients with isolated HFREF compared to patients with HFREF+CKD (all pts with iron deficiency).
- Trial name
- Iron Turtle (NCT03079518)
- Testing
- Ferric Carboxymaltose, blood withdrawal
- Where
- Germany
- Volunteers
- 23 people
- Sponsor
- RWTH Aachen University
Heart Failure
C-Pulse IDE Feasibility Study- A Heart Assist System
The C-Pulse Feasibility Study is evaluating the safety and performance of a new product for the treatment of heart failure. The product is designed to help reduce the symptoms of heart failure and help patients function better…
- Trial name
- NCT00815880
- Testing
- C-Pulse™ (Implantable Counterpulsation Therapy)
- Where
- 6 sites in United States
- Volunteers
- 21 people
- Sponsor
- Nuwellis, Inc.
Chronic Heart Failure
Influence of Exercise Therapy on Insulin Resistance in Patients With Heart Failure
The purpose of this study is to investigate the effects of a combined training programme on insulin resistance, exercise tolerance, muscle strength, body composition and cardiac function in chronic heart failure patients.
- Trial name
- NCT02000479
- Testing
- training
- Volunteers
- 29 people
- Sponsor
- Hasselt University
Heart Failure
Sensor-controlled Digital Game for Heart Failure Self-management
This study evaluates a sensor-controlled digital game (SCDG) to motivate self-management behaviors of weight monitoring and physical activity in older adults with heart failure (HF).
- Trial name
- NCT03947983
- Testing
- Sensor-controlled digital game (SCDG), Sensor Only
- Where
- 2 sites in United States
- Volunteers
- 38 people
- Sponsor
- University of Texas at Austin
Heart Failure
Warfarin and Antiplatelet Therapy in Chronic Heart Failure
Whether patients with chronic heart failure (CHF) should be anticoagulated is one of the oldest unresolved questions in cardiovascular therapeutics.
- Trial name
- NCT00007683
- Testing
- Warfarin titrated to an INR of 2.5-3.0, Aspirin, Clopidogrel 75
- Where
- 134 sites in United States, Canada and 1 more
- Volunteers
- 1,587 people
- Sponsor
- US Department of Veterans Affairs
Heart Failure
A Phase 1 Trial to Determine Dosimetry, Biodistribution and Safety of LMI 1195-101 in Healthy Subjects and Patients With Heart Failure
The purpose of this clinical study is to estimate the safety and radiation dosimetry of a single dose of LMI1195 in healthy subjects and heart failure patients undergoing positron emission tomography (PET)
- Trial name
- NCT00891241
- Testing
- LMI 1195-101
- Where
- 2 sites in United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Lantheus Medical Imaging
Cardiovascular Diseases, Heart Diseases
Epidemiology of Depression and Heart Failure in Aging
To understand how depression leads to congestive heart failure (CHF) in older adults.
- Conditions
- Cardiovascular Diseases, Heart Diseases, Heart Failure, Heart Failure, Congestive
- Trial name
- NCT00241761
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Heart Failure, Defibrillators, Implantable
Precision Event Monitoring for Patients With Heart Failure Using HeartLogic
The goal of the PREEMPT-HF study is to collect device and clinical event data to evaluate extended applications of the HeartLogic Heart Failure Diagnostic (HeartLogic) in a broad spectrum of heart failure patients with an…
- Conditions
- Heart Failure, Defibrillators, Implantable, Monitoring, Physiologic, Cardiac Resynchronization Therapy
- Trial name
- PREEMPT-HF (NCT03579641)
- Testing
- HeartLogic Sensors
- Where
- 88 sites in United States, Australia and 11 more
- Volunteers
- 2,184 people
- Sponsor
- Boston Scientific Corporation
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