Clinical trials: Congestive Heart Failure, completed
Heart Failure, Health Education
Heart Failure and Therapeutic Education
This study looks at whether a special program called the Heart Failure Therapeutic Education Unit (UTIC) helps reduce hospital stays for people with heart failure.
- Conditions
- Heart Failure, Health Education, Diet, Sodium-Restricted, Disease Management
- Trial name
- NCT07006350
- Where
- France
- Volunteers
- 104 people
- Sponsor
- Centre Hospitalier de Gonesse
Breast Cancer Female, Heart Failure
Prevention of Cardiac Dysfunction During Breast Cancer Therapy
Breast cancer is the most common cancer among women. The modern post-surgery treatment with chemotherapy, immunotherapy, radiation and hormone therapy has improved the overall 5-years survival drastically.
- Trial name
- PRADAII (NCT03760588)
- Testing
- Sacubitril/valsartan
- Where
- 4 sites in Norway
- Volunteers
- 138 people
- Sponsor
- Torbjorn Omland
Heart Failure, Mitral Valve Insufficiency
The CorCinch - Functional Mitral Valve Regurgitation (FMR) Study
This is a multi-center, non-randomized, prospective Early Feasibility Study to evaluate the AccuCinch® Ventricular Restoration System in patients with symptomatic heart failure and concomitant functional mitral regurgitation that…
- Conditions
- Heart Failure, Mitral Valve Insufficiency, Cardiomyopathies
- Trial name
- NCT02806570
- Testing
- Mitral valve repair
- Where
- 16 sites in United States
- Volunteers
- 35 people
- Sponsor
- Ancora Heart, Inc.
Heart Failure
Canadian e-Platform to Promote Behavioral Self-Management in Chronic Heart Failure: CHF-CePPORT
Chronic Heart Failure (CHF) is a growing public health issue in Canada. Hospital re-admission within 1-year after diagnosis is 25-40%, and the 5-year rate of CHF death is 50%.
- Trial name
- CHF-CePPORT (NCT01864369)
- Testing
- eCounseling + Usual Care
- Where
- 3 sites in Canada
- Volunteers
- 248 people
- Sponsor
- University Health Network, Toronto
Anthracyclines-Induced Cardiotoxicity, Cardiotoxicity
Dapagliflozin to Prevent Anthracycline-Induced Cardiotoxicity
Anthracyclines, such as doxorubicin, are effective anticancer agents but may cause dose-dependent cardiac injury, including early changes in left ventricular function and cardiac biomarkers.
- Trial name
- DAPA-AIC (NCT06888505)
- Testing
- Dapagliflozin (Forxiga)
- Where
- Iraq
- Volunteers
- 94 people
- Sponsor
- Hawler Medical University
Cardiomyopathy, Heart Failure
International T1 Multicentre CMR Outcome Study
Myocardial fibrosis is the fundamental substrate for the development of heart failure. Cardiovascular magnetic resonance (CMR) allows non-invasive assessment of myocardial fibrosis based on late gadolinium enhancement (LGE) and…
- Conditions
- Cardiomyopathy, Heart Failure, Coronary Artery Disease, Chronic Kidney Diseases
- Trial name
- T1-CMR (NCT02407197)
- Where
- 4 sites in Australia, Germany and 1 more
- Volunteers
- 1,629 people
- Sponsor
- King's College London
Acute Heart Failure
Parameters of Cardiac Indices on the Ultrasonic Cardiac Output Monitor As Potential Indicators for Predicting the Achievement of Ultrafiltration Endpoint for Acute Heart Failure Treatment
Background: The feasibility of the ultrasonic cardiac output monitor (USCOM)applying for determining ultrafiltration (UF) endpoints during acute heart failure (AHF) treatments was evaluated.
- Trial name
- NCT06533124
- Testing
- The ultrasonic cardiac output monitor 1A system (USCOM Ltd., Sydney, Australia) is a non-invasive Doppler stroke volume (SV) technique derived from echocardiography.
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Shanghai Tong Ren Hospital
Heart Failure, Self Care
The Turkish Validity-Reliability Study of the European Heart Failure Self-Care Behavior Scale-Caregivers Version
The aim of this study was to evaluate the translation, cross-cultural fit, and psychometric properties of the European Heart Failure Self-Care Behavior Questionnaire for Caregivers.
- Trial name
- NCT05420688
- Testing
- Heart Failure Group
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Harran University
Heart Failure, Diastolic, Obesity
Exercise Intolerance in Elderly Patients With Diastolic Heart Failure
The purpose of this study is to examine the effects of weight loss via hypocaloric diet, aerobic exercise training, combined hypocaloric diet and exercise training, and attention control in patients with heart failure and a…
- Trial name
- SECRET (NCT00959660)
- Testing
- Exercise, Dietary Intervention, Diet and exercise
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Wake Forest University
Heart Failure, Reduced Ejection Fraction
Study on the Effects of Sacubitril/Valsartan on Physical Activity and Sleep in Heart Failure With Reduced Ejection Fraction Patients.
The purpose of this study was to investigate the effects of initiation of sacubitril/valsartan vs enalapril treatment on objective measures of both waking activity and sleep in subjects with heart failure with reduced ejection…
- Trial name
- AWAKE-HF (NCT02970669)
- Testing
- sacubitril/valsartan (LCZ696), enalapril
- Where
- 23 sites in United States
- Volunteers
- 140 people
- Sponsor
- Novartis Pharmaceuticals
Heart Failure
A Telerehabilitation Intervention for People With Heart Failure and Chronic Fatigue
This study compares the effectiveness of a 6-week Energy Conservation + Problem Solving Therapy Intervention to Health Education Intervention for reducing the fatigue impact and fatigue level and improving the level of…
- Trial name
- NCT03820674
- Testing
- Energy Conservation plus Problem Solving Therapy, Health Education Intervention
- Volunteers
- 23 people
- Sponsor
- East Carolina University
Heart Failure
The Effect of Glucagon-Like Peptide-1 (GLP-1) on Pulmonary Vascular Resistance (PVR) in Patients With Heart Failure
This study aims to assess the effect of glucagon-like peptide-1 on cardiac output and transpulmonary gradient in patients undergoing right heart catheterisation for clinical reasons.
- Trial name
- NCT02129179
- Testing
- Glucagon-Like Peptide 1
- Where
- United Kingdom
- Volunteers
- 10 people
- Sponsor
- Papworth Hospital NHS Foundation Trust
Refractory Heart Failure, Chronic Kidney Disease
The Role of Peritoneal Dialysis in Patients With Refractory Heart Failure and Chronic Kidney Disease
In patients with advanced heart failure (HF), systemic congestion is the main indication for hospitalization. Recent evidence has highlighted the role of fluid retention in the pathogenesis of renal dysfunction and subsequent…
- Trial name
- NCT01758627
- Testing
- Peritoneal dialysis (PD)
- Where
- South Korea
- Volunteers
- 7 people
- Sponsor
- Yonsei University
Dilated Cardiomyopathy
Effect of Rosuvastatin on Left Ventricular Remodeling
The purpose of this study is to examine the the effect of the HMG-CoA reductase inhibitor Rosuvastatin on left ventricular remodeling in patients with dilated cardiomyopathy.
- Trial name
- NCT00505154
- Testing
- Rosuvastatin
- Where
- Norway
- Volunteers
- 75 people
- Sponsor
- Oslo University Hospital
Heart Failure
Non-invasive Pressure-Volume Analysis (NIPVA)
If the heart fails to pump a sufficient amount of blood, it is crucial to know why in order to provide the best treatment. Pressure-volume analysis is the gold standard for evaluating the heart's pumping function.
- Trial name
- NIPVA (NCT01960894)
- Where
- United Kingdom
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Asymptomatic Left Ventricular Systolic Dysfunction (Disorder), Heart Failure
ECG AI-Guided Screening for Low Ejection Fraction
This is a randomized controlled trial (RCT) to test a novel artificial intelligence (AI)-enabled electrocardiogram (ECG)-based screening tool for improving the diagnosis and management of left ventricular systolic dysfunction.
- Trial name
- EAGLE (NCT04000087)
- Testing
- AI-enabled ECG-based Screening Tool
- Where
- United States
- Volunteers
- 358 people
- Sponsor
- Mayo Clinic
NYHA Class III Heart Failure
Wireless, Intermittent Monitoring of Right Heart Pressures in HF
The purpose of the trial is to evaluate the wireless monitoring of pulmonary artery pressure using the CardioMEMS HF Pressure Measurement System in adult subjects with NYHA Class III Heart Failure.
- Trial name
- NCT01162707
- Testing
- CardioMEMS HF Pressure Measurement System
- Where
- 4 sites in United States
- Volunteers
- 17 people
- Sponsor
- CardioMEMS
Heart Failure, Heart Failure, Diastolic
MyoMobile Study: App-based Activity Coaching in Patients with Heart Failure and Preserved Ejection Fraction
The MyoMobile study is a single-center, randomized, controlled three-armed cohort study with prospective data collection to investigate the effect of a personalized mobile health intervention compared to usual care on the…
- Trial name
- MyoMobile (NCT04940312)
- Testing
- App-based physical activity coaching, No Intervention: Observational Cohort, Intervention Group 1
- Where
- Germany
- Volunteers
- 193 people
- Sponsor
- Johannes Gutenberg University Mainz
Congestive Heart Failure
Post Approval Registry of Corox OTW, Endocardial, Left Ventricular Steroid Lead, Bipolar
The objective of this study is to confirm the long-term safety and reliability of the Corox OTW BP left ventricular (LV) pacing lead.
- Trial name
- CELESTIAL (NCT00810264)
- Testing
- CRT Therapy - LV Lead Registry
- Where
- 86 sites in United States
- Volunteers
- 2,499 people
- Sponsor
- Biotronik, Inc.
Heart Failure
Replication of the PARADIGM-HF Heart Failure Trial in Healthcare Claims Data.
Investigators are building an empirical evidence base for real world data through large-scale replication of randomized controlled trials.
- Trial name
- NCT04736433
- Testing
- ACE inhibitor, Sacubitril/Valsartan
- Where
- United States
- Volunteers
- 6,066 people
- Sponsor
- Brigham and Women's Hospital