Clinical trials: Congestive Heart Failure Acute
Acute Heart Failure (AHF), Cardiogenic Shock
Prolonged Nasogastric Administration of Ketones in Decompensated Heart Failure
This study will evaluate the feasibility and safety of achieving therapeutic concentrations of beta-hydroxybutyrate using continuous infusion of D-beta-hydroxybutyrate monoester administered via a nasogastric tube in patients…
- Conditions
- Acute Heart Failure (AHF), Cardiogenic Shock, Heart Failure, Ketones
- Trial name
- KADHEF-2 (NCT07527156)
- Testing
- Ketone Monoester (KE)
- Where
- Czechia
- Volunteers
- 12 people
- Sponsor
- Institute for Clinical and Experimental Medicine
Acute Decompensated Heart Failure
Pharmacokinetics of Bisoprolol and SGLT2i in Acutely Decompensated Heart Failure
The pharmacokinetics (PK) and pharmacodynamics (PD) of bisoprolol and sodium-glucose co-transporter-2 inhibitors (SGLT2i, dapagliflozin and empagliflozin) in patients with acutely decompensated heart failure (ADHF), compared to…
- Trial name
- BISO-ADHF (NCT06453577)
- Testing
- Recompensation (guideline directed medical therapy)
- Where
- Germany
- Volunteers
- 33 people
- Sponsor
- Universität des Saarlandes
Heart Failure, Decompensated Heart Failure
A Prospective, Observational, Single Centre Study to Assess the Feasibility of the Data Harvested by the Acorai Intracardiac Pressure Monitoring (ICPM) System in Predicting Prognosis in Patients Discharged From Hospital After Treatment for Acute Decompensated Heart Failure
Acorai is developing the Acorai Heart Monitor, a handheld electronic device for monitoring pressures inside the heart in a non-invasive manner, by placing the device on the chest of a patient.
- Trial name
- NCT06397833
- Testing
- Acorai ICPM system
- Where
- United Kingdom
- Volunteers
- 150 people
- Sponsor
- Royal Brompton & Harefield NHS Foundation Trust
Heart Failure, Acute Coronary Syndrome
Platform Therapeutic Education in Heart Failure and Coronary Disease
A first therapeutic education is given before patient's discharge at the hospital, then a dedicated nurse follows patients through the phone,regularly according to patients' needs, continues to give advise on risk factors…
- Conditions
- Heart Failure, Acute Coronary Syndrome, Coronary Bypass Graft Stenosis of Native Artery Graft
- Trial name
- METISCARDIO (NCT01869452)
- Testing
- therapeutic education
- Where
- 4 sites in France
- Volunteers
- 555 people
- Sponsor
- Resicard
Heart Failure; With Decompensation, Heart Failure，Congestive
Telemonitoring of Patients Admitted in Hospital at Home With Acute Decompensated Heart Failure - Pilot Study
"La Casa nel Parco" (CANP) Project is a multidisciplinary project funded by the European Union and Regione Piemonte aimed to explore innovative technology application in the care of older subjects.
- Conditions
- Heart Failure; With Decompensation, Heart Failure，Congestive, Heart Failure Acute
- Trial name
- MONTEROSA (NCT04403659)
- Testing
- Telemedicine/telemonitoring (TM) suite
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- A.O.U. Città della Salute e della Scienza
Chronic Heart Failure
Snapshot Evaluation of Acute and Chronic Heart Failure in Real Life in Turkey
This study, which will be conducted at 23 sites representing the determined NUTS-1 regions in Turkey, in which all patients who were admitted to clinic or were hospitalized with Heart Failure (Acute or Chronic) diagnosis will be…
- Trial name
- SELFIE-TR (NCT02578225)
- Testing
- Non interventional study
- Where
- 23 sites in Turkey (Türkiye)
- Volunteers
- 1,054 people
- Sponsor
- Prof. Dr. Mehmet Birhan Yılmaz
Heart Failure, Heart Failure Acute
Lesser Poland Cracovian Heart Failure Registry
The goal of Lesser Poland Cracovian Heart Failure Registry (LECRA-HF) is to expand the knowledge about acute heart failure (AHF) and its long-term prognosis.
- Trial name
- LECRA-HF (NCT05746923)
- Where
- Poland
- Volunteers
- 2,500 people
- Sponsor
- Jagiellonian University
Obstructive Sleep Apnea, Heart Failure; With Decompensation
Sleep Disordered Breathing in Acute Congestive Heart Failure
The goal of this study is to determine if sleep disordered breathing results in a measurable degree of overnight myocardial stress/injury in patients with acutely decompensated congestive heart failure.
- Trial name
- NCT03804827
- Where
- 2 sites in United States
- Volunteers
- 19 people
- Sponsor
- University of California, San Diego
Heart Failure, Acute Decompensated Heart Failure
Early Discharge With Subcutaneous Furosemide Versus Standard Care in Acute Heart Failure
This will be a prospective, cluster-randomized, crossover, non-inferiority trial of 250 participants within 48 hours of an inpatient admission for heart failure or emergency department presentation for heart failure with plans…
- Trial name
- NCT07018297
- Testing
- Early Discharge with Lasix® ONYU (furosemide injection, for subcutaneous use) using SQIN-Infusor
- Where
- 2 sites in United States
- Volunteers
- 250 people
- Sponsor
- University of Texas Southwestern Medical Center
Acute Heart Failure, COPD Exacerbation
Valsalva Manœuvre in the Diagnosis of Left Ventricular Failure in Chronic Obstructive Pulmonary Disease Exacerbation
Left ventricular failure (LVF) is a common cause of acute exacerbation of chronic obstructive pulmonary disease (AECOPD). This association is frequently underestimated with regard to the difficulty of clinical diagnosis .
- Trial name
- NCT01619540
- Testing
- Valsalva maneuver
- Where
- 4 sites in Tunisia
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of Monastir
Heart Failure, Acute Decompensated Heart Failure
Feasibility Study to Support Cardiorenal Function in Acute Decompensated Heart Failure With Diuretic Resistance
Evaluation of the safety and efficacy of the ModulHeart System in patients hospitalized with acute decompensated heart failure (ADHF) and diuretic resistance
- Conditions
- Heart Failure, Acute Decompensated Heart Failure, Cardiorenal Syndrome, Heart Failure, Congestive
- Trial name
- NCT06174623
- Testing
- ModulHeart Support
- Where
- 5 sites in Australia, Georgia
- Volunteers
- 5 people
- Sponsor
- Puzzle Medical Devices Inc.
Heart Failure, Acute Heart Failure
Acetazolamide in Patients With Acute Heart Failure
Introduction: Recent studies have suggested that the use of acetazolamide may assist in the vol- ume management of patients with decompensated heart failure (HF).
- Trial name
- ACETA (NCT03720288)
- Testing
- Acetazolamide
- Where
- Brazil
- Volunteers
- 90 people
- Sponsor
- University of Sao Paulo General Hospital
Heart Diseases, Heart Valve Diseases
Acute Kidney Injury After Cardiac Surgery
The study aims to identify the Following: - 1. incidence and mortality of cardiac Surgery associated -AKI based on the new consensus diagnostic systems of KDIGO (Kidney Disease Improving Global Outcomes). 2.
- Conditions
- Heart Diseases, Heart Valve Diseases, Heart Shock, Cardiac Disease
- Trial name
- NCT05079724
- Testing
- Cardiac Surgery
- Volunteers
- 200 people
- Sponsor
- Assiut University
Dyspnea, Heart Failure
The Triple A Initiative Study ("Aktionsbündnis Akute Atemnot")
Acute dyspnea is a common chief complaint of patients presenting to the emergency department. Patients with acute dyspnea display a high mortality rate.
- Trial name
- NCT02049853
- Testing
- NTproBNP measurement with point of care device "Cobash232" in the POCT group
- Where
- 6 sites in Germany
- Volunteers
- 67 people
- Sponsor
- Prof. Dr. Michael Christ
Heart Failure Acute
Pragmatic Urinary Sodium-based Treatment algoritHm in Acute Heart Failure
Administration of loop diuretics to achieve decongestion is the current cornerstone of therapy for acute heart failure. Unfortunately, there is a lack of evidence of how to guide diuretic treatment.
- Trial name
- PUSH-AHF (NCT04606927)
- Testing
- Natriuresis
- Where
- Netherlands
- Volunteers
- 310 people
- Sponsor
- University Medical Center Groningen
Heart Failure
Balance and Executive Function in Middle-age and Older Patients With Heart Failure in Post-Acute Care Program
This trial is a single-center clinical trial in Taiwan with an expected enrollment of 60 people in Taiwan. The purpose of this trial is to compare the performance of middle-aged and elderly patients with subacute heart failure…
- Trial name
- NCT06463496
- Where
- Taiwan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Chang Chia-Jung
Acute Kidney Injury, Renal Insufficiency, Chronic
Acute Kidney Injury Genomics and Biomarkers in TAVR Study
In the last decade, transcatheter aortic valve replacement (TAVR) has become an increasingly utilized alternative procedure for replacing a stenotic aortic valve.
- Conditions
- Acute Kidney Injury, Renal Insufficiency, Chronic, Heart Failure, Myocardial Infarction
- Trial name
- NCT02791880
- Testing
- Transcatheter Aortic Valve Replacement
- Where
- 3 sites in United States
- Volunteers
- 61 people
- Sponsor
- University of Texas Southwestern Medical Center
Heart Failure, Myocardial Infarction
Evaluation of the Safety and Efficacy of Using Insulin-like Growth Factor-1 in Patients With a Heart Attack
When a patient has a heart attack, a blockage occurs in a coronary artery that delivers oxygen to the heart muscle. The heart muscle may weaken, causing heart failure.
- Trial name
- RESUS-AMI (NCT01438086)
- Testing
- mecasermin, 0.9% sodium chloride injection
- Where
- 2 sites in Ireland, Netherlands
- Volunteers
- 47 people
- Sponsor
- University College Cork
Hypertension, Pulmonary, Ventricular Dysfunction, Left
A Study to Test the Effects of Riociguat in Patients With Pulmonary Hypertension Associated With Left Ventricular Diastolic Dysfunction
The aim of this study is to assess whether single oral doses of Riociguat safely improve the cardiovascular function in patients with pulmonary hypertension associated with left ventricular diastolic dysfunction
- Trial name
- DILATE (NCT01172756)
- Testing
- Riociguat (BAY63-2521)
- Where
- 7 sites in Austria, Czechia and 1 more
- Volunteers
- 39 people
- Sponsor
- Bayer
Acute Heart Failure, Acute Renal Failure
Recombinant BNP on Heart and Renal Function in Acute Heart Failure
The purpose of this study is to evaluate the efficacy and safety of recombinant human B-type natriuretic peptide (rhBNP) on heart and renal function in patients with acute decompensated heart failure (ADHF) and acute renal injury…
- Trial name
- NCT01625403
- Testing
- rhBNP, standard of care
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Shanghai Chest Hospital